42 results on '"Xiao-Hu Li"'
Search Results
2. FAST Detection of OH Emission in the Carbon-rich Planetary Nebula NGC 7027
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Xu-Jia Ouyang, Yong Zhang, Chuan-Peng Zhang, Peng Jiang, Jun-ichi Nakashima, Xi Chen, Hai-Hua Qiao, Xu-Ying Zhang, Hao-Min Sun, Xiao-Hu Li, and Albert Zijlstra
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Astrophysical masers ,Hydroxyl masers ,Planetary nebulae ,Circumstellar masers ,Astrophysics ,QB460-466 - Abstract
We present the first detection of the ground-state OH emission line at 1612 MHz toward the prototypical carbon-rich planetary nebula (PN) NGC 7027, utilizing the newly installed ultrawideband (UWB) receiver of the Five-hundred-meter Aperture Spherical radio Telescope (FAST). This emission is likely to originate from the interface of the neutral shell and the ionized region. The other three ground-state OH lines at 1665, 1667, and 1721 MHz are observed in absorption and have velocities well matched with that of HCO ^+ absorption. We infer that the OH absorption is from the outer shell of NGC 7027, although the possibility that they are associated with a foreground cloud cannot be completely ruled out. All the OH lines exhibit a single blueshifted component with respect to the central star. The formation of OH in carbon-rich environments might be via photodissociation-induced chemical processes. Our observations offer significant constraints for chemical simulations, and they underscore the potent capability of the UWB receiver of FAST to search for nascent PNe.
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- 2024
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3. Gout of feet and ankles in different disease durations: diagnostic value of single-source DECT and evaluation of urate deposition with a novel semi-quantitative DECT scoring system
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Jin Shang, Xiao-Hu Li, Shu-Qin Lu, Yi Shang, Lu-Lu Li, and Bin Liu
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Gout ,Dual-energy spectral CT ,Scoring method ,Disease duration ,Artifact ,Clinical trial ,Diseases of the musculoskeletal system ,RC925-935 ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Abstract Objectives To investigate the diagnostic performance of single-source dual-energy computed tomography (DECT) based on gemstone spectral imaging technology (including Discovery CT750HD and Revolution CT) in patients with suspected feet/ankles gouty arthritis, and evaluate the urate deposition with a novel semi-quantitative DECT scoring system. Methods A total of 196 patients were consecutively included. Feet and ankles were evaluated in all patients by single-source DECT scan. The 2015 EULAR/ACR criteria were used as the reference for the diagnosis of gout. The sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) of DECT for the diagnosis of gout in the early (≤1 year), middle (1–3 years), and late (> 3 years) disease durations were calculated. Besides, a novel semi-quantitative DECT scoring system was assessed for the measurement of urate deposition, and the correlation between the scores and the clinical and serological data were also evaluated. Moreover, the influences of artifacts on the diagnostic performance of DECT were also determined. Results The sensitivity, specificity, and AUC of DECT in 196 patients were 38.10, 96.43%, and 0.673 in the early-stage group; 62.96, 100.00%, and 0.815 in the middle-stage group; and 77.55, 87.50%, and 0.825 in the late-stage group, respectively. The overall diagnostic accuracies in the AUC of DECT (Discovery CT750HD and Revolution CT) in the middle and late stages of gout were higher than that in the early stage of gout. Besides, the monosodium urate crystals were deposited on the first metatarsophalangeal joints and ankles/midfeet. Age, the presence of tophus, bone erosion, and disease duration considerably affected the total urate score. No statistical difference in the positive detection of nail artifact, skin artifact, vascular calcification, and noise artifact was found between the case and control groups. Conclusion DECT (Discovery CT750HD and Revolution CT) showed promising diagnostic accuracy for the detection of urate crystal deposition in gout but had limited diagnostic sensitivity for short-stage gout. Longer disease duration, the presence of tophus, and bone erosion were associated with the urate crystal score system. The artifacts do not remarkably affect the diagnostic performance of DECT in gout.
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- 2021
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4. Manganese migration behavior in the RH vacuum process of manganese-containing steel
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Lei SONG, Min WANG, Xin LI, Zhen-bo GAO, Xiao-hu LI, and Yan-ping BAO
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rh vacuum treatment ,mn gasification ,splash ,nodulation ,step vacuum ,Mining engineering. Metallurgy ,TN1-997 ,Environmental engineering ,TA170-171 - Abstract
The Ruhrstahl Heraeus (RH) refining furnace is a piece of important secondary refining equipment that is widely used in the production of special steel owing to its high efficiency of degassing, decarburization, and de-intercalation. However, molten steel that has a high alloy content will encounter key problems in the vacuum treatment process, and the loss of volatile alloying elements in the molten steel is considerable, resulting in the nodulation of the molten steel vacuum splashing and secondary oxidation of the subsequent molten steel. To address the problems of elemental loss and vacuum splashing caused by manganese (Mn) gasification during the vacuum processing of manganese-containing steel using RH, the variation and migration behavior of Mn in molten steel under different vacuum treatment conditions of 120 t RH were examined. This study analyzed the relationship between manganese elemental loss and its volatilization and vacuum splattering, and it was verified in an anatomical experiment of the nodule at different positions inside the RH vacuum chamber. The results show that elemental Mn in the molten steel shows obvious loss during the vacuum process of RH, and the loss in the early stage of the vacuum process is the largest. The composition of manganese oxide in the nodule of the RH vacuum chamber is as high as 14%–70%, and the thermodynamic calculation results show that temperature, the content of Mn in the steel, and the degree of vacuum have a considerable influence on the volatilization behavior of Mn, which is the key influencing factor for manganese migration during the vacuum process. By improving the vacuum pressure drop mode, a stepwise vacuum is used to reduce the loss of elemental Mn from the original 2×10−4 to 1×10−4. The results have considerable significance for on-site production, and steel can be effectively restrained by improving the vacuum pressure drop mode. Additionally, the splashing and volatilization of liquid reduces the loss of the alloying element Mn.
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- 2020
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5. Salt responsive alternative splicing of a RING finger E3 ligase modulates the salt stress tolerance by fine-tuning the balance of COP9 signalosome subunit 5A.
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Yuan Zhou, Xiao-Hu Li, Qian-Huan Guo, Peng Liu, Ying Li, Chang-Ai Wu, Guo-Dong Yang, Jin-Guang Huang, Shi-Zhong Zhang, Cheng-Chao Zheng, and Kang Yan
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Genetics ,QH426-470 - Abstract
Increasing evidence points to the tight relationship between alternative splicing (AS) and the salt stress response in plants. However, the mechanisms linking these two phenomena remain unclear. In this study, we have found that Salt-Responsive Alternatively Spliced gene 1 (SRAS1), encoding a RING-Type E3 ligase, generates two splicing variants: SRAS1.1 and SRAS1.2, which exhibit opposing responses to salt stress. The salt stress-responsive AS event resulted in greater accumulation of SRAS1.1 and a lower level of SRAS1.2. Comprehensive phenotype analysis showed that overexpression of SRAS1.1 made the plants more tolerant to salt stress, whereas overexpression of SRAS1.2 made them more sensitive. In addition, we successfully identified the COP9 signalosome 5A (CSN5A) as the target of SRAS1. CSN5A is an essential player in the regulation of plant development and stress. The full-length SRAS1.1 promoted degradation of CSN5A by the 26S proteasome. By contrast, SRAS1.2 protected CSN5A by competing with SRAS1.1 on the same binding site. Thus, the salt stress-triggered AS controls the ratio of SRAS1.1/SRAS1.2 and switches on and off the degradation of CSN5A to balance the plant development and salt tolerance. Together, these results provide insights that salt-responsive AS acts as post-transcriptional regulation in mediating the function of E3 ligase.
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- 2021
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6. Supercritical CO2 Foaming of Radiation Cross-Linked Isotactic Polypropylene in the Presence of TAIC
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Chen-Guang Yang, Mou-Hua Wang, Ming-Xing Zhang, Xiao-Hu Li, Hong-Long Wang, Zhe Xing, Lin-Feng Ye, and Guo-Zhong Wu
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polypropylene ,TAIC ,radiation cross-linking ,supercritical carbon dioxide ,foaming ,Organic chemistry ,QD241-441 - Abstract
Since the maximum foaming temperature window is only about 4 °C for supercritical CO2 (scCO2) foaming of pristine polypropylene, it is important to raise the melt strength of polypropylene in order to more easily achieve scCO2 foaming. In this work, radiation cross-linked isotactic polypropylene, assisted by the addition of a polyfunctional monomer (triallylisocyanurate, TAIC), was employed in the scCO2 foaming process in order to understand the benefits of radiation cross-linking. Due to significantly enhanced melt strength and the decreased degree of crystallinity caused by cross-linking, the scCO2 foaming behavior of polypropylene was dramatically changed. The cell size distribution, cell diameter, cell density, volume expansion ratio, and foaming rate of radiation-cross-linked polypropylene under different foaming conditions were analyzed and compared. It was found that radiation cross-linking favors the foamability and formation of well-defined cell structures. The optimal absorbed dose with the addition of 2 wt % TAIC was 30 kGy. Additionally, the foaming temperature window was expanded to about 8 °C, making the handling of scCO2 foaming of isotactic polypropylene much easier.
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- 2016
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7. P‐114: A Method for Visualizing and Quantifying Color Differences using Relative Hue and Relative Color Concentration and its Application.
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Han-yan, SUN, Xiao-hu, LI, Wei-tao, CHEN, Xiao-peng, CUI, and Jian-guo, XING
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PROBLEM solving ,TEST methods ,PHOSPHORS ,VISUALIZATION ,STATISTICAL reliability - Abstract
This paper innovates a method for visualizing and quantifying color differences using relative hue and relative color concentration. Firstly, the relative hue and relative color concentration are proposed to solve the problem that conventional chromaticity parameters can't characterize color difference. Secondly, the color difference visualization and quantification method realized by weighting algorithm and VB programming can replace the conventional qualitative assessment by human eyes, which greatly improves the accuracy and repeatability. Finally, this paper takes the color difference problem of 2 a‐Si products as an example, and uses the method of this paper to test and analyze, and easily clarifies the cause of color difference as the uneven thickness of Panel SINx film layer and the slow settling rate of LED phosphor. Combined with principle analysis, optical simulation, and experimental verification, this paper finally proposes an improvement plan to solve the stubborn color difference problem of a‐Si products. [ABSTRACT FROM AUTHOR]
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- 2024
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8. The SnapShot Freeze Algorithm Improves Image Quality of Coronary Computed Tomography Angiography Using High-Resolution Wide-Detector CT.
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Xiao-Ying Zhao, Xiao-Hu Li, Jian Song, Bin Liu, and Xing-Wang Wu
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- 2019
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9. Gout of feet and ankles in different disease durations: diagnostic value of single-source DECT and evaluation of urate deposition with a novel semi-quantitative DECT scoring system
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Lu-Lu Li, Xiao-Hu Li, Yi Shang, Shu-Qin Lu, Bin Liu, and Jin Shang
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medicine.medical_specialty ,Scoring system ,Gout ,Metatarsophalangeal joints ,Scoring method ,Diseases of the musculoskeletal system ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Internal medicine ,medicine ,Humans ,Stage (cooking) ,Dual-energy spectral CT ,Disease duration ,030203 arthritis & rheumatology ,Receiver operating characteristic ,business.industry ,Arthritis, Gouty ,Tophus ,Digital Enhanced Cordless Telecommunications ,RC581-607 ,medicine.disease ,Uric Acid ,Clinical trial ,medicine.anatomical_structure ,RC925-935 ,Artifact ,Ankle ,Immunologic diseases. Allergy ,Nuclear medicine ,business ,Tomography, X-Ray Computed - Abstract
Objectives To investigate the diagnostic performance of single-source dual-energy computed tomography (DECT) based on gemstone spectral imaging technology (including Discovery CT750HD and Revolution CT) in patients with suspected feet/ankles gouty arthritis, and evaluate the urate deposition with a novel semi-quantitative DECT scoring system. Methods A total of 196 patients were consecutively included. Feet and ankles were evaluated in all patients by single-source DECT scan. The 2015 EULAR/ACR criteria were used as the reference for the diagnosis of gout. The sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) of DECT for the diagnosis of gout in the early (≤1 year), middle (1–3 years), and late (> 3 years) disease durations were calculated. Besides, a novel semi-quantitative DECT scoring system was assessed for the measurement of urate deposition, and the correlation between the scores and the clinical and serological data were also evaluated. Moreover, the influences of artifacts on the diagnostic performance of DECT were also determined. Results The sensitivity, specificity, and AUC of DECT in 196 patients were 38.10, 96.43%, and 0.673 in the early-stage group; 62.96, 100.00%, and 0.815 in the middle-stage group; and 77.55, 87.50%, and 0.825 in the late-stage group, respectively. The overall diagnostic accuracies in the AUC of DECT (Discovery CT750HD and Revolution CT) in the middle and late stages of gout were higher than that in the early stage of gout. Besides, the monosodium urate crystals were deposited on the first metatarsophalangeal joints and ankles/midfeet. Age, the presence of tophus, bone erosion, and disease duration considerably affected the total urate score. No statistical difference in the positive detection of nail artifact, skin artifact, vascular calcification, and noise artifact was found between the case and control groups. Conclusion DECT (Discovery CT750HD and Revolution CT) showed promising diagnostic accuracy for the detection of urate crystal deposition in gout but had limited diagnostic sensitivity for short-stage gout. Longer disease duration, the presence of tophus, and bone erosion were associated with the urate crystal score system. The artifacts do not remarkably affect the diagnostic performance of DECT in gout.
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- 2021
10. Enhanced refractory organics removal by
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Chao, Qu, Yan-Gang, Li, Shu-Juan, Meng, Xiao-Hu, Li, Shu-Jun, Zhang, and Da-Wei, Liang
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Recently, carbon nanotubes coated carbon black and polytetrafluoroethylene (CNTs-C/PTFE) gas diffusion electrode was used as an air-cathode in an electro-oxidation (EO) system for effectively generating hydrogen peroxide (H
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- 2022
11. Effect of surface H$_2$ on molecular hydrogen formation on interstellar grains
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Gang Zhao, Qiang Chang, Xia Zhang, Donghui Quan, Yong Zhang, and Xiao-Hu Li
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Space and Planetary Science ,Astrophysics of Galaxies (astro-ph.GA) ,FOS: Physical sciences ,Astronomy and Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We investigate how the existence of hydrogen molecules on grain surfaces may affect H$_2$ formation efficiency in diffuse and translucent clouds. Hydrogen molecules are able to reduce the desorption energy of H atoms on grain surfaces in models. The detailed microscopic Monte Carlo method is used to perform model simulations. We found that the impact of the existence of H$_2$ on H$_2$ formation efficiency strongly depends on the diffusion barriers of H$_2$ on grain surfaces. Diffuse cloud models that do not consider surface H$_2$ predict that H atom recombination efficiency is above 0.5 over a grain temperature (T) range 10 K and 14 K. The adopted H$_2$ diffusion barriers in diffuse cloud models that consider surface H$_2$ are 80$\%$ H$_2$ desorption energies so that H$_2$ can be trapped in stronger binding sites. Depending on model parameters, these diffuse cloud models predict that the recombination efficiency is between nearly 0 and 0.5 at 10 K $\leq$ T $\leq$ 14 K. Translucent cloud model results show that H$_2$ formation efficiency is not affected by the existence of surface H$_2$ if the adopted average H$_2$ diffusion barrier on grain surfaces is low (194 K) so that H$_2$ can diffuse rapidly on grain surfaces. However, the recombination efficiency can drop to below 0.002 at T $\geq$ 10 K if higher average H$_2$ diffusion barrier is used (255 K) in translucent cloud models., Comment: accepted for publication in MNRAS
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- 2022
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12. Enhanced Refractory Organics Removal by •Oh and 1o2 Generated in an Electro-Oxidation System with Cathodic Fenton-Like Reaction
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Chao Qu, Yan-gang Li, Shu-juan Meng, Xiao-hu Li, Shu-jun Zhang, and Da-wei Liang
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Environmental Engineering ,Health, Toxicology and Mutagenesis ,Environmental Chemistry ,Pollution ,Waste Management and Disposal - Published
- 2022
13. A Novel Dual-Layer Element for Wideband and Highly Efficient Transmitarray Antenna
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Xiao-Hu Li, Gang Zhao, Xin-Yun Wen, Xu-Hong Jiang, and Wei Wu
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- 2021
14. A Novel Magneto-Electric Dipole for Wideband Application
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Wei Wu, Rui Li, Hui Liu, and Xiao-Hu Li
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- 2021
15. Methyl jasmonate enhances rice tolerance to alkaline stress via the auxin pathway
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Chun-Lan Chen, Di Wu, Qian-Kun Li, Xiao-hu Liu, Xu-Guang Niu, Guo-Xian Zhang, Yong-Yong Zhang, Hui Zhang, and Chang-Jie Jiang
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Rice (Oryza sativa L.) ,Alkaline stress ,Methyl jasmonate (MeJA) ,Auxin ,Phytohormone ,Crosstalk ,Plant ecology ,QK900-989 - Abstract
Soil alkalization is a major challenge for global crop production. This study reveals a novel defense mechanism in rice seedlings against alkaline stress, involving methyl jasmonate (MeJA) and auxin pathways. Under alkaline stress (15 mM Na2CO3), rice seedlings exhibited elevated levels of endogenous MeJA and upregulation of JA-responsive genes. Pre-treatment with MeJA (50 µM) significantly improved seedling survival, growth, and mitigated root damage under alkaline stress. This treatment also upregulated genes associated with cell death suppression (OsBI1) and stress tolerance (OsJRL, OsNAC). Notably, MeJA pre-treatment increased auxin (indole-3-acetic acid, IAA) levels in roots, and upregulated genes involved in IAA synthesis (OASA1, OASA2) and auxin signaling (Aux/IAA, ARFs). Blocking auxin transport with N-1-naphthylphthalamic acid intensified root damage under alkaline stress and diminished the protective effect of MeJA. These results highlight the crucial role of MeJA-induced activation of auxin pathway in enhancing rice tolerance to alkaline stress, and provide valuable insights for developing strategies to improve crop resilience in alkaline soils.
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- 2024
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16. The SnapShot Freeze Algorithm Improves Image Quality of Coronary Computed Tomography Angiography Using High-Resolution Wide-Detector CT
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Xing-Wang Wu, Bin Liu, Xiao-Ying Zhao, Xiao-Hu Li, and Jian Song
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business.industry ,Computer science ,Image quality ,Detector ,Coronary computed tomography angiography ,Snapshot (computer storage) ,High resolution ,Health Informatics ,Radiology, Nuclear Medicine and imaging ,Computer vision ,Artificial intelligence ,business - Abstract
Objective: The aim of this study was to investigate the effect the motion-correction reconstruction algorithm SnapShot Freeze (SSF) on the diagnostic performance of coronary computed tomography angiography (CCTA) using high-resolution, wide-detector CT. Methods: CCTA was performed using an electrocardiography-triggered auto-gating protocol in 62 patients. All images were reconstructed using both standard algorithm and motioncorrection algorithm (SSF). According to the American Heart Association (AHA) guidelines for coronary angiography, the coronary artery was divided into 15 segments. The coronary artery segments were evaluated using a 4-point Likert scale to determine the image quality. Arteries with a score greater than 1 were further evaluated by two expert radiologists blinded to conditions. The diagnostic performance of SSF was compared in the patients with high heart rate (HR ≥ 75 beats per minute) compared to low HR (< 75 beats per minute). Results: At the segmental level, the Likert score for segments 1–4 and 6–14 were higher in SSF compared to standard algorithm (p < 0.05). The proportion of images that was improved by SSF was greater for the high HR systolic phase imaging (66.7%) than for the low HR diastolic phase imaging (34.3%, p < 0.05). Conclusion: The SSF algorithm improves coronary CTA images acquired using a 256-row wide detector CT, compared to standard algorithm, particularly in patients with high HR.
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- 2019
17. The MALATANG survey:dense gas and star formation from high-transition HCN and HCO+ maps of NGC 253
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Timothy A. Davis, Christine D. Wilson, Aeree Chung, Xue-Jian Jiang, Satoki Matsushita, Thomas R. Greve, Richard de Grijs, Mark G. Rawlings, C. Yang, Yinghe Zhao, Yu Gao, Zhi-Yu Zhang, David Eden, Jinhua He, Luis C. Ho, Daizhong Liu, Ming Zhu, Bumhyun Lee, Michał J. Michałowski, Nanase Harada, Malcolm J. Currie, Elias Brinks, Xiao-Hu Li, Masatoshi Imanishi, Yiping Ao, Yong Shi, Qinghua Tan, Matthew Smith, and Qian Jiao
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TRACERS ,FOS: Physical sciences ,Astrophysics ,Concentration indices ,01 natural sciences ,0103 physical sciences ,individual: NGC 253 [galaxies] ,NEARBY GALAXIES ,ISM [submillimetre] ,010303 astronomy & astrophysics ,NUCLEUS ,James Clerk Maxwell Telescope ,molecules [ISM] ,Physics ,NGC-253 ,ISM [galaxies] ,010308 nuclear & particles physics ,Star formation ,Spatially resolved ,Astronomy and Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Galaxy ,MOLECULAR GAS ,Stars ,Space and Planetary Science ,Astrophysics of Galaxies (astro-ph.GA) ,STARBURST ,LUMINOSITY ,star formation [galaxies] ,SPIRAL GALAXIES - Abstract
To study the high-transition dense-gas tracers and their relationships to the star formation of the inner $\sim$ 2 kpc circumnuclear region of NGC253, we present HCN $J=4-3$ and HCO$^+ J=4-3$ maps obtained with the James Clerk Maxwell Telescope (JCMT). With the spatially resolved data, we compute the concentration indices $r_{90}/r_{50}$ for the different tracers. HCN and HCO$^+$ 4-3 emission features tend to be centrally concentrated, which is in contrast to the shallower distribution of CO 1-0 and the stellar component. The dense-gas fraction ($f_\text{dense}$, traced by the velocity-integrated-intensity ratios of HCN/CO and HCO$^+$/CO) and the ratio $R_\text{31}$ (CO 3-2/1-0) decline towards larger galactocentric distances, but increase with higher SFR surface density. The radial variation and the large scatter of $f_\text{dense}$ and $R_\text{31}$ imply distinct physical conditions in different regions of the galactic disc. The relationships of $f_\text{dense}$ versus $\Sigma_\text{stellar}$, and SFE$_\text{dense}$ versus $\Sigma_\text{stellar}$ are explored. SFE$_\text{dense}$ increases with higher $\Sigma_\text{stellar}$ in this galaxy, which is inconsistent with previous work that used HCN 1-0 data. This implies that existing stellar components might have different effects on the high-$J$ HCN and HCO$^+$ than their low-$J$ emission. We also find that SFE$_\text{dense}$ seems to be decreasing with higher $f_\text{dense}$, which is consistent with previous works, and it suggests that the ability of the dense gas to form stars diminishes when the average density of the gas increases. This is expected in a scenario where only the regions with high-density contrast collapse and form stars., Comment: accepted to MNRAS
- Published
- 2020
18. Salt responsive alternative splicing of a RING finger E3 ligase modulates the salt stress tolerance by fine-tuning the balance of COP9 signalosome subunit 5A
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Jinguang Huang, Kang Yan, Xiao-Hu Li, Ying Li, Guodong Yang, Peng Liu, Shizhong Zhang, Chengchao Zheng, Changai Wu, Qian-Huan Guo, and Yuan Zhou
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Salinity ,Leaves ,Cancer Research ,Physiology ,Arabidopsis ,Plant Science ,QH426-470 ,Plant Reproduction ,Salt Stress ,Biochemistry ,Genetically Modified Plants ,Ligases ,Cell Signaling ,Plant Resistance to Abiotic Stress ,Seed Germination ,Gene expression ,Protein Isoforms ,Arabidopsis thaliana ,Genetics (clinical) ,Ecology ,biology ,Plant Anatomy ,Genetically Modified Organisms ,Eukaryota ,Plants ,Signaling Cascades ,Enzymes ,Cell biology ,Ubiquitin ligase ,medicine.anatomical_structure ,Experimental Organism Systems ,Plant Physiology ,RNA splicing ,Engineering and Technology ,Genetic Engineering ,Research Article ,Signal Transduction ,Biotechnology ,Ubiquitin-Protein Ligases ,Arabidopsis Thaliana ,Bioengineering ,Brassica ,Genes, Plant ,Research and Analysis Methods ,Stress Signaling Cascade ,Model Organisms ,Plant and Algal Models ,Plant-Environment Interactions ,Genetics ,Ring finger ,medicine ,Plant Defenses ,COP9 signalosome ,Molecular Biology ,Ecology, Evolution, Behavior and Systematics ,Arabidopsis Proteins ,COP9 Signalosome Complex ,Plant Ecology ,Ecology and Environmental Sciences ,Alternative splicing ,Organisms ,Biology and Life Sciences ,Proteins ,Cell Biology ,Plant Pathology ,biology.organism_classification ,Alternative Splicing ,Proteasome ,Seedlings ,Enzymology ,Animal Studies ,biology.protein ,Plant Biotechnology - Abstract
Increasing evidence points to the tight relationship between alternative splicing (AS) and the salt stress response in plants. However, the mechanisms linking these two phenomena remain unclear. In this study, we have found that Salt-Responsive Alternatively Spliced gene 1 (SRAS1), encoding a RING-Type E3 ligase, generates two splicing variants: SRAS1.1 and SRAS1.2, which exhibit opposing responses to salt stress. The salt stress-responsive AS event resulted in greater accumulation of SRAS1.1 and a lower level of SRAS1.2. Comprehensive phenotype analysis showed that overexpression of SRAS1.1 made the plants more tolerant to salt stress, whereas overexpression of SRAS1.2 made them more sensitive. In addition, we successfully identified the COP9 signalosome 5A (CSN5A) as the target of SRAS1. CSN5A is an essential player in the regulation of plant development and stress. The full-length SRAS1.1 promoted degradation of CSN5A by the 26S proteasome. By contrast, SRAS1.2 protected CSN5A by competing with SRAS1.1 on the same binding site. Thus, the salt stress-triggered AS controls the ratio of SRAS1.1/SRAS1.2 and switches on and off the degradation of CSN5A to balance the plant development and salt tolerance. Together, these results provide insights that salt-responsive AS acts as post-transcriptional regulation in mediating the function of E3 ligase., Author summary High salinity severely affects plant growth and development, impairing crop production worldwide. E3 ligase is a stress-responsive regulator through ubiquitin-proteasome system for selective protein degradation. The E3s are regulated by transcriptional regulation and post-translational modifications. Here, we have discovered that stress-responsive AS acts as a post-transcriptional regulation modulating the function of E3 ligases. Intriguingly, the truncated proteins generated by salt-responsive AS play opposite roles compared with the full-length E3 ligase. The truncated isoform losing key domain could not degrade the target protein, instead, it interacts and competes with the E3 ligase through binding the same domain of the targets. This finding contributes significantly to a deeper mechanistic understanding of how AS regulates the function of E3 ligase in response to salt stress.
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- 2021
19. On the encounter desorption of hydrogen atoms on an ice mantle
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Xia Zhang, Long-Fei Chen, Qiang Chang, Donghui Quan, Yang Lu, Qingkuan Meng, Xiao-Hu Li, and Xu-Li Zheng
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Physics ,Astrochemistry ,Hydrogen ,FOS: Physical sciences ,chemistry.chemical_element ,Astronomy and Astrophysics ,Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Mantle (geology) ,Astrophysics - Solar and Stellar Astrophysics ,chemistry ,Space and Planetary Science ,Chemical physics ,Astrophysics of Galaxies (astro-ph.GA) ,Desorption ,Solar and Stellar Astrophysics (astro-ph.SR) - Abstract
At low temperatures (10 K), hydrogen atoms can diffuse quickly on grain ice mantles and frequently encounter hydrogen molecules, which cover a notable fraction of grain surface. The desorption energy of H atoms on H2 substrates is much less than that on water ice. The H atom encounter desorption mechanism is adopted to study the enhanced desorption of H atoms on H2 substrates. Using a small reaction network, we show that the steady-state surface H abundances predicted by the rate equation model that includes H atom encounter desorption agree reasonably well with the results from the more rigorous microscopic Monte Carlo method. For a full gas-grain model, H atom encounter desorption can reduce surface H abundances. Therefore, if a model adopts the encounter desorption of H atoms, it becomes more difficult for hydrogenation products such as methanol to form, but it is easier for C, O and N atoms to bond with each other on grain surfaces., 11 pages, 6 figures, Accepted for publication in Research in Astronomy and Astrophysics (RAA)
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- 2021
20. Molecular mechanisms of synergistic induction of apoptosis by the combination therapy with hyperthermia and cisplatin in prostate cancer cells
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Yin-rui Lei, Xiangming Yan, Xiao-hu Li, Jian-fu Zhang, Yifeng Guo, Fang Guo, Bin Lan, and Shuai Gao
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Male ,0301 basic medicine ,Hot Temperature ,Time Factors ,Combination therapy ,Cell Survival ,medicine.medical_treatment ,Blotting, Western ,Cell ,Poly (ADP-Ribose) Polymerase-1 ,Biophysics ,Antineoplastic Agents ,Apoptosis ,Pharmacology ,Biochemistry ,Inhibitor of Apoptosis Proteins ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Cell Line, Tumor ,LNCaP ,medicine ,Animals ,Humans ,Molecular Biology ,Cell Proliferation ,Cisplatin ,Chemotherapy ,Dose-Response Relationship, Drug ,Caspase 3 ,business.industry ,Prostatic Neoplasms ,Cell Biology ,medicine.disease ,030104 developmental biology ,medicine.anatomical_structure ,Proto-Oncogene Proteins c-bcl-2 ,030220 oncology & carcinogenesis ,Signal transduction ,Apoptosis Regulatory Proteins ,business ,Signal Transduction ,medicine.drug - Abstract
Prostate Cancer has become the second leading cause of male cancer-related incidence and mortality in United States. Hyperthermia (HT) is known to serve as a powerful tool in treatment of prostate cancer in clinical. The combination treatment with HT and cisplatin has a synergistic effect to inhibit prostate cancer progression and demonstrates better clinical effectiveness than HT or chemotherapy alone. But molecular mechanisms of this phenomenon have not been illuminated clearly. In this study, we used MTS assay to examine cell viabilities of PC-3, LNCaP, DU-145 and RM-1 cells after treated by HT and cisplatin. Then colony formation of PC-3 and DU-145 cells after treated with HT and cisplatin were photographed. To investigate whether the combination therapy would enhance apoptosis of PC-3 and DU-145 cells, we used Western blot analysis to detect expression level of proteins on apoptosis-regulated signaling pathway in PC-3 and DU-145 cells. Our results showed that the combination treatment decreased cell viabilities and colony formation of prostate cancer cells in a dose-dependent manner and this combination therapy enhanced apoptosis of PC-3 and DU-145 cells via activation of Caspase-3 and cleavage of PARP. We also found that the combination therapy could down-regulate the anti-apoptotic Bcl-2 and IAP family proteins. At last, the combination therapy activated AMPKα-JNK signaling pathway and inhibited Akt-mTOR-p70s6k signaling pathway to promote apoptosis of PC-3 and DU-145 cells. In conclusion, this study clearly elucidated how the combination therapy with HT and cisplatin promoted apoptosis of prostate cancer cells in synergy.
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- 2016
21. Circumferential nonlocal effect on the buckling and vibration of nanotubes
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Xiao Hu Li, Chengyuan Wang, and Ying Luo
- Subjects
Physics ,SHELL model ,General Physics and Astronomy ,02 engineering and technology ,Radius ,021001 nanoscience & nanotechnology ,Aspect ratio (image) ,Vibration ,020303 mechanical engineering & transports ,Classical mechanics ,0203 mechanical engineering ,Buckling ,0210 nano-technology ,Nonlinear Sciences::Pattern Formation and Solitons ,Beam (structure) - Abstract
The nonlocal beam theories are widely used to study the mechanics of cylindrical nanotubes (NTs). The one-dimensional models however are unable to account for the nonlocal effect in the circumferential direction, which may substantially affect the applicability of the nonlocal beam models. To address the issue this letter examines the circumferential nonlocal effect (CNE) on the buckling and vibration of the NTs. Here the CNE is characterized by the difference between the nonlocal beam model considering the axial nonlocal effect only and the nonlocal shell model with both axial and circumferential nonlocal effects. The aspect ratio and radius-dependence of the CNE are calculated for the singlewall carbon NTs selected as a typical example. The results show that the CNE is substantial for the buckling and vibration of the NTs with small radius (e.g.
- Published
- 2016
22. A new data structure for accelerating kinetic Monte Carlo method
- Author
-
Hai-Long Zhang, Qiang Chang, Xu-Li Zheng, Donghui Quan, Olli Sipilä, and Xiao-Hu Li
- Subjects
Physics ,Space and Planetary Science ,Astronomy and Astrophysics ,Kinetic Monte Carlo ,Astrophysics ,Data structure ,Computational physics - Abstract
The kinetic Monte Carlo simulation is a rigorous numerical approach to study the chemistry on dust grains in cold dense interstellar clouds. By tracking every single reaction in chemical networks step by step, this approach produces more precise results than other approaches but takes too much computing time. Here we present a method of a new data structure, which is applicable to any physical conditions and chemical networks, to save computing time for the Monte Carlo algorithm. Using the improved structure, the calculating time is reduced by 80 percent compared with the linear structure when applied to the osu-2008 chemical network at 10 K. We investigate the effect of the encounter desorption in cold cores using the kinetic Monte Carlo model with an accelerating data structure. We found that the encounter desorption remarkably decreases the abundance of grain-surface H2 but slightly influences the abundances of other species on the grain.
- Published
- 2019
23. The MALATANG survey: The L GAS–L IR correlation on sub-kiloparsec scale in six nearby star-forming galaxies as traced by HCN J = 4 → 3 and HCO+ J = 4 → 3
- Author
-
Junfeng Wang, Hao Chen, Xue-Jian Jiang, Ashley Bemis, Joanna Bulger, Satoki Matsushita, Erik Rosolowsky, Sherry Yeh, Jianfa Wang, Harriet Parsons, Yong Shi, Bumhyun Lee, Jinhua He, Jianjie Qiu, David Eden, Qinghua Tan, C. Yang, Yinghe Zhao, Junzhi Wang, Scott Chapman, Michał J. Michałowski, Mark G. Rawlings, Walter Kieran Gear, Qian Jiao, Aeree Chung, Qiusheng Gu, Matthew Smith, Daizhong Liu, Kotaro Kohno, Thomas R. Greve, Xiao-Hu Li, Timothy A. Davis, Christine D. Wilson, Dimitra Rigopoulou, Richard de Grijs, Malcolm J. Currie, Yu Gao, Zhi-Yu Zhang, Elias Brinks, Ming Zhu, Luis C. Ho, Yiping Ao, Masatoshi Imanishi, Giulio Violino, Quang Nguyen-Luong, and Lijie Liu
- Subjects
Physics ,Luminous infrared galaxy ,Star formation ,Spatially resolved ,FOS: Physical sciences ,Astronomy and Astrophysics ,Quasar ,Astrophysics ,01 natural sciences ,Astrophysics - Astrophysics of Galaxies ,Flux ratio ,Galaxy ,Full width at half maximum ,Space and Planetary Science ,Astrophysics of Galaxies (astro-ph.GA) ,0103 physical sciences ,010306 general physics ,010303 astronomy & astrophysics ,James Clerk Maxwell Telescope ,QC ,QB - Abstract
We present HCN J=4-3 and HCO^+ J=4-3 maps of six nearby star-forming galaxies, NGC 253, NGC 1068, IC 342, M82, M83, and NGC 6946, obtained with the James Clerk Maxwell Telescope as part of the MALATANG survey. All galaxies were mapped in the central 2 arcmin $\times$ 2 arcmin region at 14 arcsec (FWHM) resolution (corresponding to linear scales of ~ 0.2-1.0 kpc). The L_IR-L'_dense relation, where the dense gas is traced by the HCN J=4-3 and the HCO^+ J=4-3 emission, measured in our sample of spatially-resolved galaxies is found to follow the linear correlation established globally in galaxies within the scatter. We find that the luminosity ratio, L_IR/L'_dense, shows systematic variations with L_IR within individual spatially resolved galaxies, whereas the galaxy-integrated ratios vary little. A rising trend is also found between L_IR/L'_dense ratio and the warm-dust temperature gauged by the 70 \mu m/100 \mu m flux ratio. We find the luminosity ratios of IR/HCN(4-3) and IR/HCO^+(4-3), which can be taken as a proxy for the efficiency of star formation in the dense molecular gas (SFE_dense), appears to be nearly independent of the dense-gas fraction (f_dense) for our sample of galaxies. The SFE of the total molecular gas (SFE_mol) is found to increase substantially with f_dense when combining our data with that on local (ultra)luminous infrared galaxies and high-z quasars. The mean L'_HCN(4-3)/L'_HCO^+(4-3) line ratio measured for the six targeted galaxies is 0.9+/-0.6. No significant correlation is found for the L'_HCN(4-3)/L'_HCO^+(4-3) ratio with the SFR as traced by L_IR, nor with the warm-dust temperature, for the different populations of galaxies., Comment: 29 pages, 12 figures, accepted for publication in ApJ
- Published
- 2018
24. Combination therapy with BH3 mimetic and hyperthermia tends to be more effective on anti-melanoma treatment
- Author
-
Xiao-hu Li, Xuefeng Wang, Bin Lan, Ganggang Zhang, Zhen Shi, Baowei Peng, and Fang Guo
- Subjects
0301 basic medicine ,MAPK/ERK pathway ,Hyperthermia ,Male ,Lung Neoplasms ,Skin Neoplasms ,Combination therapy ,Biophysics ,Melanoma, Experimental ,Apoptosis ,Biochemistry ,Inhibitor of Apoptosis Proteins ,03 medical and health sciences ,Mice ,0302 clinical medicine ,Biomimetics ,Cell Movement ,Cell Line, Tumor ,medicine ,Combined Modality Therapy ,Animals ,Humans ,Microwaves ,Molecular Biology ,Melanoma ,PI3K/AKT/mTOR pathway ,business.industry ,Gossypol ,Cell migration ,Cell Biology ,Hyperthermia, Induced ,medicine.disease ,Mice, Inbred C57BL ,030104 developmental biology ,030220 oncology & carcinogenesis ,Cancer research ,business ,BH3 Interacting Domain Death Agonist Protein ,Signal Transduction - Abstract
Malignant melanoma has shown increased incidence and high mortality rate in the last three decades. In this study, we investigated whether combination therapy with ch282-5 (a novel BH3 mimetic) and microwave hyperthermia could display synergistic antitumor effects against melanoma. Our results indicated that combination therapy reduced the viability and proliferation of melanoma cells. Through inhibiting the expression of anti-apoptotic proteins of Bcl-2 and IAP family and activating MAPK proteins, combined hyperthermia enhanced ch282-5-induced apoptosis. Combination therapy also synergistically disturbed the mTOR/p70S6k signaling pathway, which is important for cell survival and migration. Moreover, our results showed that combination therapy remarkably suppressed melanoma cell migration in vitro and significantly reduced experimental pulmonary metastasis in vivo. In conclusion, our results indicate that combination therapy with ch282-5 and hyperthermia has synergistic antitumor effects and provides a possible therapeutic strategy for advanced melanoma.
- Published
- 2018
25. Finite Element Analysis of Composite Shear Walls with Double Steel Plates and Filled Concrete for a Nuclear Island Structure under In-Plane Loading
- Author
-
Xiao-Hu Li, Xiao-Jun Li, Xiao-Hui Wang, and Fang-Fang Li
- Published
- 2017
26. Supercritical CO2 Foaming of Radiation Cross-Linked Isotactic Polypropylene in the Presence of TAIC
- Author
-
Honglong Wang, Zhe Xing, Guozhong Wu, Lin-Feng Ye, Mingxing Zhang, Xiao-Hu Li, Mouhua Wang, and Chenguang Yang
- Subjects
Materials science ,Polymers ,Pharmaceutical Science ,02 engineering and technology ,Radiation ,Polypropylenes ,010402 general chemistry ,01 natural sciences ,Article ,Analytical Chemistry ,Cell size ,lcsh:QD241-441 ,Crystallinity ,chemistry.chemical_compound ,supercritical carbon dioxide ,lcsh:Organic chemistry ,Tacticity ,Drug Discovery ,Cell density ,Polymer chemistry ,polypropylene ,TAIC ,radiation cross-linking ,foaming ,Cobalt Radioisotopes ,Physical and Theoretical Chemistry ,Polypropylene ,Organic Chemistry ,Temperature ,Carbon Dioxide ,021001 nanoscience & nanotechnology ,Supercritical fluid ,0104 chemical sciences ,Allyl Compounds ,Cross-Linking Reagents ,Monomer ,Chemical engineering ,chemistry ,Gamma Rays ,Chemistry (miscellaneous) ,Molecular Medicine ,0210 nano-technology - Abstract
Since the maximum foaming temperature window is only about 4 degrees C for supercritical CO2 (scCO(2)) foaming of pristine polypropylene, it is important to raise the melt strength of polypropylene in order to more easily achieve scCO(2) foaming. In this work, radiation cross-linked isotactic polypropylene, assisted by the addition of a polyfunctional monomer (triallylisocyanurate, TAIC), was employed in the scCO(2) foaming process in order to understand the benefits of radiation cross-linking. Due to significantly enhanced melt strength and the decreased degree of crystallinity caused by cross-linking, the scCO(2) foaming behavior of polypropylene was dramatically changed. The cell size distribution, cell diameter, cell density, volume expansion ratio, and foaming rate of radiation-cross-linked polypropylene under different foaming conditions were analyzed and compared. It was found that radiation cross-linking favors the foamability and formation of well-defined cell structures. The optimal absorbed dose with the addition of 2 wt % TAIC was 30 kGy. Additionally, the foaming temperature window was expanded to about 8 degrees C, making the handling of scCO(2) foaming of isotactic polypropylene much easier.
- Published
- 2016
- Full Text
- View/download PDF
27. Research progress on ocular biomarkers for the occurrence and progression of retinal vein occlusion
- Author
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Zhong-Yue Zhang, Xiao-Hu Liu, Li-Ping Wang, Jian-Qiang Xiao, and Guo-Ping Wang
- Subjects
retinal vein occlusion ,ocular biomarkers ,optical coherence tomography ,ischemia ,visual acuity ,Ophthalmology ,RE1-994 - Abstract
The second most prevalent retinal vascular disease after diabetic retinopathy(DR)is retinal vein occlusion(RVO). Ocular biomarkers, including disorganization of retinal inner layers(DRIL), paracentral acute middle maculopathy(PAMM), prominent middle limiting membrane(p-MLM), hyperreflective foci(HRF), subretinal fluid(SRF), ellipsoid zone(EZ), external limiting membrane(ELM), superficial capillary plexus(SCP), and deep capillary plexus(DCP), etc., are indicators or signs derived from auxiliary examinations that can anticipate the onset and progression of diseases as well as the final visual outcome, according to research published in recent years. In our study, we evaluated the ocular biomarkers of RVO in the hopes that these markers would offer a multifaceted picture of the onset and development of RVO, assist in determining the prognosis of RVO, provide a more thorough understanding of the disease and avoid the severe vision impairment of RVO.
- Published
- 2022
- Full Text
- View/download PDF
28. Sensing water in organic solvent using a polyurethane-silica hybrid membrane doped with a luminescent ruthenium complex
- Author
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Shihua Huang, Feng Teng, Hongshang Peng, Xiao-Hu Li, and Fangtian You
- Subjects
Materials science ,Annealing (metallurgy) ,Inorganic chemistry ,Doping ,chemistry.chemical_element ,Nanochemistry ,Analytical Chemistry ,Ruthenium ,chemistry.chemical_compound ,Membrane ,chemistry ,Acetone ,Luminescence ,Polyurethane - Abstract
We have prepared an ~1.4 μm thin hybrid film from polyurethane (PU) hydrogel and tetraethylorthosilicate (TEOS) by a sol–gel method, and have incorporated the red-luminescent ruthenium-tris-bipyridyl complex. At an optimized ratio of PU/TEOS (1.5:1; w/w) and annealing temperature (60 °C), the membrane sensor exhibits good capability to extract water from organic solvents but also can well retain the ruthenium dye. If contacted with water-containing organic solvents such as acetone or THF, both the luminescence intensity and wavelength change significantly. The response of luminescence intensity to the water fraction in organics is sigmoidal, which can be well fitted with a modified Stern-Volmer equation. The sensor works in the ranges of 0–6 % and 0–12 % (v/v) of water in acetone and THF, respectively, with detection limits of 0.13 % and 0.486 % (v/v).
- Published
- 2013
29. Simulation of Electric Power Fluctuate Affect Transformer Substation Bus Voltage Wave by PSASP
- Author
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Xu Yao, Yi Kang, Xiao Hu Li, Yin Li Cao, Hong Lei Xu, and Xue Shi Li
- Subjects
Engineering ,business.industry ,General Engineering ,Electrical engineering ,Distribution transformer ,Grid ,law.invention ,Electric power system ,Bus voltage ,Transmission line ,law ,Electric power ,business ,Transformer ,Voltage - Abstract
This paper listed the mathematic model of transmission line firstly, and PSASP was used to simulate the fluctuate voltage of transformer substation which affected by wind generate electric power capacity which combined to the grid changed and the power flow of XINJIANG sent into GANSU changed. At the end, the conclusion and construction of improve grid running state was presented.
- Published
- 2012
30. Experiment Research on Compressive Strength of Specified Density Steel Fiber Concrete
- Author
-
Xiao Hu Li, Yan Kun Zhang, Pan Zhang, and Zhen Lei Guo
- Subjects
Volume content ,Aggregate (composite) ,Materials science ,business.industry ,General Engineering ,Structural engineering ,Experimental research ,Specific strength ,Compressive strength ,Ultimate tensile strength ,Prism ,Fiber ,Composite material ,business - Abstract
Based on the experimental research, the prism compressive strength and cubic compressive strength of specified density steel fiber concrete are studied. Through regression analysis, the influence of type of steel fiber, volume content of the fiber and substitution ratio of lightweight aggregate is studied. According to the test results, the formula of prism compressive strength and cubic compressive strength is given.
- Published
- 2011
31. Experimental Research on Tensile Strength of Specified Density Steel Fiber Concrete
- Author
-
Xiao Hu Li, Pan Zhang, and Yan Kun Zhang
- Subjects
Volume content ,Materials science ,Aggregate (composite) ,business.industry ,General Engineering ,Structural engineering ,Experimental research ,Specific strength ,Compressive strength ,Ultimate tensile strength ,Fiber ,Composite material ,business ,Tensile testing - Abstract
Based on the experiment, the splitting tensile strength and axial tensile strength of specified density steel fiber concrete are studied. The influence of type of steel fiber, volume content of the fiber and substitution ratio of lightweight aggregate is analyzed. The relationship between splitting tensile strength and axial tensile strength of specified density steel fiber concrete is suggested.
- Published
- 2011
32. Characteristics of distribution and chemical speciation of heavy metals in environmental mediums around Jinchang mining city, Northwest China
- Author
-
Feng-You Chu, Zhong-Li Tang, Ling-Yuan Yang, and Xiao-Hu Li
- Subjects
Pollutant ,Global and Planetary Change ,Chemistry ,Extraction (chemistry) ,Soil Science ,Geology ,Contamination ,Pollution ,Tailings ,law.invention ,Metal ,Wastewater ,law ,visual_art ,Environmental chemistry ,Soil water ,visual_art.visual_art_medium ,Environmental Chemistry ,Atomic absorption spectroscopy ,Earth-Surface Processes ,Water Science and Technology - Abstract
Heavy metal contamination was the main environmental problem around the Jinchang Ni–Cu mine area of Gansu, Northwest China. The concentration of heavy metals (Cr, Cu, Ni, Pb, and Zn) in various environmental mediums around the Jinchang Ni–Cu mine area were analyzed using atomic absorption spectrometry (AAS). The different chemical speciation of heavy metals was extracted using BCR (European Community Bureau of Reference) sequential extraction procedure, and the concentration of chemical speciation of each heavy metal was measured by inductively coupled plasma-atomic emission spectrometry. The results showed that Cu and Ni were the most important heavy metal pollutants in various mediums including cultivated soils, dust on slagheap surfaces, tailings, and sediments in waste water drains. In the tailings and sediments, the concentrations of Ni were obviously higher than those of Cu, whereas, in the soil and dust, the concentrations of Cu were higher than those of Ni. Analysis of chemical speciation indicated that Cr and Zn were mainly in residual fraction; Cu was mainly in oxidizable fraction; Ni was mainly in reducible fraction and acid soluble fraction; and Pb was mainly in reducible fraction and residual fraction. The extent of contamination of various environmental mediums was different because the heavy metals were derived from different sources. Furthermore, the mobility of various heavy metals was different because of the different distribution of chemical speciation.
- Published
- 2010
33. Cassiterite U-Pb dating and micro-XRF analysis constraint on the formation of Xinlu Sn-Zn deposit, South China
- Author
-
Chang-Hao Xiao, Ping-Ping Yu, Xiao-Hu Liu, Xiang-Chong Liu, Yan-Wen Tang, Wen-Lei Wang, and Yu Zhang
- Subjects
micro-XRF ,Xinlu deposit ,Nanling Sn-W belt ,South China ,Paleo-Pacific ,cassiterite U-Pb geochronology ,Science - Abstract
This study presents rock slab and thin section reflection mapping, element mapping by Micro-XRF (μ-XRF) analysis, and in situ cassiterite U-Pb laser ablation-inductively coupled plasma mass spectrometer (LA-ICP-MS) ages of the Xinlu Sn-Zn deposit, Nanling Sn-W belt, South China. The new results provided constraints on the age and processes of Sn mineralization and thus further discussed the role of the Paleo-Pacific plate in the formation of Sn-W mineralization in the Nanling Sn-W belt. Based on mineralogy and μ-XRF analysis, four mineralization episodes are distinguished in the Baimianshan segment, Xinlu deposit, including 1) prograde skarn stage characterized by the mineral assemblages of garnet, pyroxene, marble, hornfels; 2) retrograde skarn-sulfide composed of massive pyrrhotite, sphalerite with parts of epidote, cassiterite; 3) quartz sulfide vein stage consisting of arsenopyrite, pyrite, quartz, and 4) barren calcite crosscutting the former episodes. The time of retrograde skarn-sulfide mineralization is dated by LA-ICP-MS cassiterite U-Pb at 168.7 ± 1.3 Ma. These U-Pb ages, combined with previous geochronological studies, support one Sn mineralization event associated with the 159.5–168.7 Ma magmatism in the Guposhan-Huashan district. The Xinlu Sn-Zn mineralization and the Middle-Late Jurassic Sn-W mineralization in the Nanling belt, South China is genetically related to asthenospheric upwelling and crust-mantle interaction caused by the subduction of the Paleo-Pacific plate. Our results demonstrate that thin section reflection and μ-XRF element mapping are powerful tools for determining paragenesis in ore deposits and are highly effective to guide the selection of analytical positions for cassiterite U-Pb dating. This method may also be applicable to in-situ geochronology of other minerals.
- Published
- 2023
- Full Text
- View/download PDF
34. Correlation between CT attenuation value and iodine concentration in vitro: discrepancy between gemstone spectral imaging on single-source dual-energy CT and traditional polychromatic X-ray imaging
- Author
-
Le, Wang, Bin, Liu, Xing-Wang, Wu, Jie, Wang, Yong, Zhou, Wan-Qin, Wang, Xiao-Hong, Zhu, Yong-Qiang, Yu, Xiao-Hu, Li, Shuai, Zhang, and Yun, Shen
- Subjects
Radiographic Image Enhancement ,Phantoms, Imaging ,X-Ray Film ,Statistics as Topic ,Contrast Media ,Humans ,Radiographic Image Interpretation, Computer-Assisted ,Reproducibility of Results ,Tomography, X-Ray Computed ,Sensitivity and Specificity ,Algorithms ,Iodine - Abstract
To assess the relation between CT attenuation value and iodine concentration in vitro, using gemstone spectral imaging (GSI) with single-source dual-energy CT and traditional polychromatic X-ray imaging (TPXI), respectively.A polypropylene phantom with eight test tubes in which iodine concentrations of solution were 0.4, 0.7, 2, 5, 10, 20, 30 and 50 mg/mL underwent GSI and traditional polychromatic X-ray scans (80, 100, 120 and 140 kV(p)), using single-source dual-energy spectral CT (Discovery CT750HD; GE Healthcare Technologies, Milwaukee, WI, USA) at the same tube speed of 0.8 s/rotation. All spectral imaging data were analysed with GSI viewer to obtain monochromatic images (50-140 keV, interval of 10 keV). Computed tomography attenuation values of iodine solution were measured with the same size of regions of interest and at the exact same level for both monochromatic and polychromatic images. The relation between CT attenuation value and iodine concentration was examined.A linear correlation was found between CT attenuation value and iodine concentration for both monochromatic and polychromatic images. Moreover, the fitting coefficients for CT attenuation values and iodine concentrations were closer to one with GSI (r(2) = 0.99824-0.99996) than that with TPXI (r(2) = 0.99640-0.99736).Owing to the better correlation coefficients between CT attenuation value and iodine concentration, GSI may be a preferred method for quantitative measurement compared with TPXI.
- Published
- 2012
35. Wind Power Prediction Considering the Layout of the Wind Turbines and Wind Direction
- Author
-
Xiao-Hu Li, Guan Tieying, Tianqi Liu, Zhen-Huan Chen, Wang Fujun, and Xiang Chen
- Subjects
Wind power ,Meteorology ,business.industry ,Astrophysics::High Energy Astrophysical Phenomena ,Crew ,Wind direction ,Wind speed ,Power (physics) ,Term (time) ,Wind profile power law ,Physics::Space Physics ,Astrophysics::Solar and Stellar Astrophysics ,Environmental science ,Power output ,business ,Physics::Atmospheric and Oceanic Physics ,Marine engineering - Abstract
It Points out that when the wind farms are undertaking the short-term forecast , wind power will be all crew for a machine to equivalent the whole prediction of the deficiencies, and through the forecast of the contrast, it proves the influence of the overall prediction power according to the units in different layouts .Considering the wind power prediction ,the established prediction model of wind farms super short term is be tested by the example,which improves that wind speed has greater influence on the overall power output and it is important to predict the wind direction when predict the speed in order to improve the prediction precision of power .
- Published
- 2012
36. [Study on electroporation of rare Actinomycete Micromonospora sp. 40027 with Streptomyces plasmid pSET152]
- Author
-
Xiao-hu, Li, Ci-fan, Long, Xiu-fen, Zhou, and Zi-xin, Deng
- Subjects
Electroporation ,Transformation, Bacterial ,Micromonospora ,Soil Microbiology ,Plasmids - Abstract
Electroporation of Micromonospora sp. 40027 isolated from soil was studied with Streptomyces plasmid pSET152, an integrative vector commonly used in Streptomyces genetic manipulation. Transformant was not obtained by electroporation with germinated spores of Micromonospora sp. 40027 as recipient, but plasmid pSET152 can be electroporated into the fresh mycelium of Micromonospora sp. 40027, and the highest electroporation efficiency was yielded under the electric field strength of 13kV/cm. Plasmid stability experiment and southern blot showed that pSET152 could stably exist in the Micromonospora sp. 40027, and was integrated into its chromosome via the attP site, originated from Streptomyces phage phiC31. These data suggested that plasmid pSET152 was successfully electroporated into Micromonospora, and that the integrase gene and attP site of Streptomyces phage phiC31 could play the same role in Micromonospora.
- Published
- 2007
37. [Epidemiological study on injuries among children in Beijing]
- Author
-
Guang, Zeng, Yu-tian, Geng, Rui-wei, Jing, Xiao-hu, Li, Shu-quan, Qu, Lan-ping, Li, Ai-hua, Hao, Min, Yuan, and Michael, Linnan
- Subjects
Male ,China ,Risk Factors ,Child, Preschool ,Humans ,Infant ,Wounds and Injuries ,Female ,Morbidity ,Child - Abstract
To explore the morbidity, burdens caused and risk factors of injuries among children and to provide information for policy making on prevention.By PPS sampling method, we selected 28 000 households in Beijing and using a questionnaire developed by UNICEF, TASC and China CDC.The morbidity of child injury in Beijing was 2.25%, higher than that of adults (1.56%) with 6-9 year group the highest (2.83% ). The morbidity of boys was 3.04% higher than that of girls (1.37%). Among the 7 death cases, 3 were caused by injury(2 RTA, 1 drowning). The three leading causes of injuries were fall, animal bite and road traffic accident in children. Among children aged 0-5 years, fall, animal and burn/machine injuries were the leading causes. Among children aged 0-5 years, the leading causes were hurt by animals, fall and RTA with the leading causes as fall, sprain and RTA. The average medical cost of injury cases was 1617.57 Yuan. There were 3500 children (injured orphan) whose parents were injured leading to death or disability in Beijing in 2003.Injury was the leading cause of child deaths in Beijing with children of 6-9 years old having the highest morbidity with RTA the most severe type of injuries in Beijing which affects both children and their parents.
- Published
- 2007
38. Dependence of Switching Current Distribution of a Current-Biased Josephson Junction on Microwave Frequency
- Author
-
Peiheng Wu, Jiquan Zhai, Guo-Zhu Sun, Jianxin Shi, Weiwei Xu, Yongchao Li, Xiao-Hu Li, and Yu Zhou
- Subjects
Pi Josephson junction ,Josephson effect ,Physics ,Condensed matter physics ,Condensed Matter::Superconductivity ,Excited state ,Master equation ,Range (statistics) ,General Physics and Astronomy ,Biasing ,Current (fluid) ,Quantum - Abstract
We investigate the distribution of the switching current of a current-biased Josephson junction (CBJJ) and its dependence on the microwave frequency using two theoretical methods, one of which is the quantum trajectory method and the other is the master equation method. Both the methods show that the distribution of the switching current of CBJJ will exhibit double peaks in a certain range of microwave frequency if proper microwave power is given, and the gap between the two peaks will increase with the microwave frequency. The obtained results can be used to identify the energy difference of the ground and first excited states in a Josephson junction for any bias current.
- Published
- 2015
39. Supercritical CO2 Foaming of Radiation Cross-Linked Isotactic Polypropylene in the Presence of TAIC.
- Author
-
Chen-Guang Yang, Mou-Hua Wang, Ming-Xing Zhang, Xiao-Hu Li, Hong-Long Wang, Zhe Xing, Lin-Feng Ye, and Guo-Zhong Wu
- Subjects
POLYPROPYLENE ,SURFACE active agents ,MONOMERS ,CRYSTALLINITY ,CELL size - Abstract
Since the maximum foaming temperature window is only about 4 °C for supercritical CO
2 (sc CO2 ) foaming of pristine polypropylene, it is important to raise the melt strength of polypropylene in order to more easily achievesc CO2 foaming. In this work, radiation cross-linked isotactic polypropylene, assisted by the addition of a polyfunctional monomer (triallylisocyanurate, TAIC), was employed in thesc CO2 foaming process in order to understand the benefits of radiation cross-linking. Due to significantly enhanced melt strength and the decreased degree of crystallinity caused by cross-linking, thesc CO2 foaming behavior of polypropylene was dramatically changed. The cell size distribution, cell diameter, cell density, volume expansion ratio, and foaming rate of radiation-cross-linked polypropylene under different foaming conditions were analyzed and compared. It was found that radiation cross-linking favors the foamability and formation of well-defined cell structures. The optimal absorbed dose with the addition of 2 wt % TAIC was 30 kGy. Additionally, the foaming temperature window was expanded to about 8 °C, making the handling ofsc CO2 foaming of isotactic polypropylene much easier. [ABSTRACT FROM AUTHOR]- Published
- 2016
- Full Text
- View/download PDF
40. [Efficacy of imatinib mesylate, a specific inhibitor of BCR/ABL tyrosine kinase, on chronic myeloid leukemia in blast phase]
- Author
-
Guo-Cai, Zhang, Dong, Zheng, Qun-Hua, Li, Xiao-Hu, Li, Cheng-Cai, Cai, Shao-Kai, Luo, Juan, Li, Ai-Hua, Peng, Xiu-Zhen, Tong, En-Xun, Tan, and Wen-De, Hong
- Subjects
Adult ,Male ,Adolescent ,Remission Induction ,Fusion Proteins, bcr-abl ,Antineoplastic Agents ,Middle Aged ,Protein-Tyrosine Kinases ,Piperazines ,Survival Rate ,Pyrimidines ,Drug Resistance, Neoplasm ,Recurrence ,Leukemia, Myelogenous, Chronic, BCR-ABL Positive ,Benzamides ,Imatinib Mesylate ,Humans ,Female ,Blast Crisis ,Aged - Abstract
Chronic myeloid leukemia (CML) in blast phase is refractory with a poor prognosis. This study was to evaluate efficacy of imatinib mesylate, a specific inhibitor of BCR/ABL tyrosine kinase, on CML in blast phase.Nineteen patients with CML in blast phase (imatinib treatment group) received induction of cytarabine-based standard chemotherapy for 2 cycles, and 400 mg/d of imatinib mesylate for 4 weeks. Patients with no remission received 600 mg/d of imatinib mesylate for another 8 weeks. Treatment of 600 mg/d of imatinib mesylate was maintained if it showed effects after 8 weeks, otherwise it would be stopped. Twenty-two patients with CML in blast phase (historical control group) received inducement of cytarabine-based chemotherapy for 2 cycles, and other regimens of consolidation or continuous induction.Sixteen patients of imatinib treatment group achieved no hematologic remission after induction. After treated with imatinib mesylate, 6 of 16 (38%) achieved hematologic complete remission (CHR), and major cytogenetic response; 2 of 16(13%) achieved hematologic partial remission (PHR); 1 of 16 (6%) returned to chronic phase with minor cytogenetic response. Total hematologic response rate of imatinib treatment group was 57%; 1-year survival rate was 38% (6/16). Eighteen patients of historical control group achieved no hematologic remission after inducement. After treated with other regimens, 2 (11%) achieved CHR, and 1 (6%) achieved PHR. Total hematologic response rate of historical control group was 17%; 1-year survival rate was 6%(1/18), significantly lower than that of imatinib treatment group (P0.05).Imatinib mesylate may have anti-leukemic activity, and prolong survival time of patients with CML in blast phase. But problems of tumor relapse, and drug resistance are still present.
- Published
- 2004
41. A new data structure for accelerating kinetic Monte Carlo method.
- Author
-
Xu-Li Zheng, Dong-Hui Quan, Hai-Long Zhang, Xiao-Hu Li, Qiang Chang, and Olli Sipilä
- Published
- 2019
- Full Text
- View/download PDF
42. A Kinematic Analysis on Buffering Technique in Taking-off Process of Chinese elite High Jumper Huang Haiqiang.
- Author
-
Hui-ju Pan, Xiao-hu Li, Xu-jiang Mao, and Wen-hai Shi
- Abstract
The article presents a study which examines the kinematics behind the buffering technique in taking-off process of Chinese elite high jumper Huang Haiqiang. The study was undertaken with the use of two cameras to shoot the activities of the athlete which were analyzed by SIMI software from Germany. Results show that buffering is lighter with13.24 inches knee angle at maximum buffering time. It notes that there is a disparity in Y velocities of the jump leg at taking-off.
- Published
- 2009
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