Search

Qian Xu,1 Kang Wu,2 Yi Yang,2 Rui Chang,1 Hua Qiu,2 Yingying Wang,1 Tao Lin,2 Chaowei Fu,1 Yue Chen,3 Na Wang,1 Xiaonan Ruan2 1School of Public Health, Fudan University, Pudong Preventive Medicine Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China; 2Pudong New Area Center for Disease Control and Prevention, Pudong Preventive Medicine Research Institute of Fudan University, Shanghai, 200136, People’s Republic of China; 3School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, CanadaCorrespondence: Na WangSchool of Public Health, Fudan University, Pudong Preventive Medicine Research Institute of Fudan University, No. 130, Dongan Road, Xuhui District, Shanghai, 200032, People’s Republic of ChinaTel/Fax +86 21-54237455Email na.wang@fudan.edu.cnXiaonan RuanPudong New Area Center for Disease Control and Prevention, Shanghai, 200136, People’s Republic of ChinaTel/Fax +86 21-50342409Email xnruan@pdcsc.sh.cnPurpose: Poor sleep quality and pain were common and had been proved as an important influenced factor of quality of life for patients with COPD. The association of sleep quality with pain has been observed in other population but remains unclear in mild patients with COPD from a community setting.Methods: A cross-sectional study was conducted to include eligible mild patients with COPD in Pudong New District of Shanghai. A structured questionnaire was used to collect general and clinical information for the patients. The Chinese version of Pittsburgh Sleep Quality Index (PSQI) and the short form of McGill Pain Questionnaire (SF-MPQ) was used to assess sleep quality and intensity of pain. Logistic regression was performed to test the association between sleeping quality and pain intensity.Results: Two hundred and sixty-four patients with COPD, with an average age of 64 years (SD 5.78 years), were enrolled, and of 52% were women. Seventy-one (26.9%) participants reported at least one exacerbation during the past year. About 28.2% of the patients were classified as having poor sleep quality. Sleep quality was significantly associated with PRI score (adjusted odds ratio (ORad)=2.16, 95% CI: 1.16– 4.00) and PPI rank (ORad=1.90, 95% CI: 1.08– 3.34). People with daytime disturbance were more likely to have pain (ORad =2.03, 95% CI: 1.18– 3.50).Conclusion: Poor sleep quality was common in mild patients with COPD in community and was associated with higher pain intensity. Pain may involve an impairment of sleep quality.Keywords: sleep, pain, chronic obstructive pulmonary disease, Pittsburgh sleep quality index, SF-MPQ

What is already known on this topic? The morbidity and mortality of chronic obstructive pulmonary disease (COPD) is associated with adverse weather and air pollution. However, COPD patients are not able to be alerted in advance of high risk environments. What is added by this report? This prospective controlled trial conducted in Pudong New Area of Shanghai from October 2019 to April 2020 provided evidence of COPD risk forecasting service on the reductions in visits and costs of COPD patients in outpatient and emergency departments in China for the first time. What are the implications for public health practice? This study suggests that COPD risk forecasting service could be integrated into existing COPD management in public health to improve the health and economic outcomes.

The Australian tortoise beetle Trachymela sloanei (Coleoptera: Chrysomelidae: Chrysomelinae), an invasive pest of several species of Eucalyptus has been reported for the first time in Asia. It was first detected in Shenzhen, China where it has become established. Currently, T. sloanei is not a destructive forest pest in Shenzhen. Pupae and adults were frequently found infected by an unknown fungus.

BACKGROUND Chronic obstructive pulmonary disease (COPD) is a serious disease with impaired quality of life (QoL). Few studies have focused on the QoL for mild COPD patients in Chinese urban communities. This study aimed to evaluate the QoL and explore its associated factors among patients with mild COPD in Shanghai. METHODS A cross-sectional survey of 275 mild COPD patients was conducted in 6 communities of Pudong New Area in Shanghai, China, in 2016. Data on socioeconomic and health conditions were acquired through a face-to-face interview and a physical examination. EuroQoL five-dimension questionnaire (EQ-5D)- Chinese version was applied to evaluate their QoL. Logistic regression was used to estimate odds ratios (ORs) and their 95% CI for risk factors associated with QoL. RESULTS Among 275 subjects, the overall visual analog scale score and utility of QoL were 70.6 and 0.889, respectively. Logistic regression analysis indicated that exacerbation in recent year were negatively associated with the top 25% utility of QoL (OR =2.02, 95% CI: 1.03-3.97), and the worse exercise capacity (distance of 6-minute walking test

Most previous studies on sleep duration and cardio-cerebral vascular disease (CCVD) association have not adequately controlled for many confounders. The current study prospectively examined the association of sleep duration with CCVD prevalence in a Chinese community population; cardiovascular risk factors, chronic diseases, and sleep quality were taken into consideration.A cross-sectional study conducted in Pudong New Area of Shanghai, China. Through three-stage sampling, 10,657 adults aged ≥15 years were randomly selected. Self-reported sleep duration and CCVD prevalence were obtained using a structured questionnaire. Medical records of the subjects were reviewed by investigators for further confirmation. Relationships between sleep duration and CCVD prevalence were examined using logistic regression models.Compared to midrange sleep duration (7 h), the multivariate-adjusted OR of CCVD prevalence was 1.550 (95% CI 1.192-2.017) for sleeping 5 h, 1.427 (95% CI 0.983-2.072) for sleeping5 h. A similar situation also prevailed in coronary heart disease (CHD) prevalence: the multivariate-adjusted OR of stroke prevalence was 2.130 (95% CI 1.338-3.389) for sleeping9 h. In an analysis stratified by sex, participants with a long sleep duration (9 h) demonstrated significantly increased prevalence (OR = 3.623, 95% CI 1.862-7.052) for stroke only in men.The relationship between extreme sleep durations and CCVD were influenced by sex in a Chinese community population. Further studies are needed to investigate the mechanisms of the association between extreme sleep duration and CCVD, as well as sex-specificity in the relationship.

Interarm blood pressure difference (IAD) is a risk factor for peripheral artery disease and cardio-cerebral vascular disease (CCVD). The current study examines the association of IAD with stroke and coronary heart disease in a Chinese community. A cross-sectional study was conducted in Pudong New Area in Shanghai, China. A total of 10 657 residents aged 15 years and older were randomly selected through three-stage sampling. Volunteers had systolic and diastolic blood pressure (BP) measured in both arms at recruitment, and IAD was defined in both arms as the absolute difference in BP. Medical records of study participants were reviewed by investigators to confirm measurements. Logistic regression models were used to assess the association between systolic interarm blood pressure difference (sIAD) and diastolic interarm blood pressure difference (dIAD) with stroke and coronary heart disease. Compared with dIAD

Background Chronic obstructive pulmonary disease (COPD) is a serious disease frequently accompanied by anxiety and depression. Few studies have focused on anxiety and depression for mild COPD patients in China. This study aimed to assess the prevalence and associated factors for anxiety and depression among patients with mild COPD in urban communities. Methods A cross-sectional survey of 275 mild COPD patients was conducted in 6 communities randomly sampled from Pudong New Area of Shanghai, China, in 2016. Data on socioeconomic factors and health conditions were acquired through a face-to-face interview as well as a physical examination. The Hospital Anxiety and Depression Scale (HAD) and EQ-5D visual analogue (EQ-5Dvas) were applied to evaluate their mental health and quality of life, respectively. Logistic regression model was used to estimate adjusted odds ratios (aORs) and their 95% confidential intervals (CI) for risk factors associated with anxiety or depression. Results Among 275 subjects, 8.1% had anxiety and 13.4% had depression. Logistic regression analysis indicated that female patients were more likely to suffer from anxiety than male patients (aOR = 6.41, 95% CI:1.73-23.80). Poor health status (EQ-5Dvas score

The questionnaire for COPD patients in communities of Pudong District, Shanghai. The questionnaire covered on data of geographic, socioeconomic, lifestyle and occupational exposure factors, and COPD and comorbidities. (PDF 288 kb)

The article's abstract is no available.

Tian Xiao,1,* Xianfeng Zhou,2,* Yun He,1 Yue Chen,3 Hua Qiu,2 Sheng Zhang,1 Xianglin Wei,1 Kang Wu,2 Xiaonan Ruan,2 Na Wang,1 Chaowei Fu1 1Department of Epidemiology, School of Public Health, Key Laboratory of Public Health Safety, Pudong Institute of Preventive Medicine, Fudan University, 2Department of Chronic Disease, Pudong New Area Center for Disease Control and Prevention, Shanghai, China; 3School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada *These authors contributed equally to this work. Background: Chronic obstructive pulmonary disease (COPD) is a great public health burden worldwide. Few studies have focused on pain problems in patients with mild and moderate COPD in Chinese community settings. Methods: A cross-sectional study of 283 patients with mild and moderate COPD was conducted in six communities that were randomly sampled in Pudong New Area of Shanghai, China, in 2016. A face-to-face interview was conducted to collect data on personal characteristics and health conditions. The short form McGill Pain Questionnaire and the COPD assessment test (CAT) were applied to evaluate pain problems and health status, respectively. Results: Among 283 subjects, more than one third (37%) had pain problems indicated by the present pain intensity (PPI) scale. COPD patients aged

ObjectiveDietary fibre has been linked to lower levels of glycosylated haemoglobin A1c (HbA1c) among diabetes patients. The present study aimed to evaluate the long-term effect of dietary fibre on HbA1c levels among Chinese patients with type 2 diabetes mellitus.DesignTwo cross-sectional surveys were conducted in 2006 and 2011, with the second one being a repeat survey on a sub-sample from the initial one. In both surveys, an in-person interview was conducted to collect information on demographic characteristics and lifestyles following a similar protocol. Dietary intake was assessed with a validated FFQ. Anthropometric measures and biochemical assays were performed at the interview.SettingCommunities in Pudong New Area of Shanghai, China.SubjectsChinese patients (n 934) with type 2 diabetes mellitus.ResultsAn inverse association was observed between dietary fibre and glycaemic status indicated by HbA1c level in both surveys, although it was significant only in the first survey. Among 497 patients participating in both surveys, dietary fibre intake at the first survey was inversely associated with uncontrolled glycaemic status at the second survey, with adjusted odds ratios across the tertiles of intake being 1·00, 0·72 (95 % CI 0·43, 1·21) and 0·58 (95 % CI 0·34, 0·99; Ptrend = 0·048). The change in fibre intake was slightly associated with glycaemic status, with each increase in tertile scores of intake linked to a 0·138 % (β = −0·138; 95 % CI −0·002, 0·278) decrease in HbA1c value and a 19 % (OR = 0·81; 95 % CI 0·65, 1·02) reduced risk of uncontrolled glycaemic status at the second survey.ConclusionsDietary fibre may have a long-term beneficial effect on HbA1c level among Chinese diabetes patients.

In this paper, the impact of high mobility on the constant envelope (CE) precoded multi-user massive multiple-input multiple-output (MIMO) systems is analyzed. We derive a closed-form expression for the achievable ergodic information rate taking into account the impact of channel estimation error due to high mobility. The system performance is evaluated in terms of both achievable ergodic per-user information rate and bit-error-rate (BER) by numerical simulations. The performance of systems with various configurations is presented, which shows that channel estimation error caused by high mobility degrades the performance and increasing ratio of base station (BS) antennas to users reduces the degradation of performance.

Dietary fibre intake has been suggested to reduce blood glucose levels in diabetic patients, particularly when glycosylated Hb (HbA1c) levels are high. In the present study, we used a quantile regression (QR) approach to characterise the possible heterogeneous associations of dietary fibre intake with HbA1c levels in Chinese diabetic patients. A total of 497 diabetic patients participated in the baseline survey in 2006 and in the follow-up survey in 2011, both of which were conducted in Pudong New Area of Shanghai, China. Structured in-person interviews were conducted to collect information on demographic characteristics and lifestyle factors. Dietary intake was assessed using a validated FFQ. Blood samples were collected during the interviews for biochemical assays. QR models were used to examine the heterogeneous associations of dietary factors with HbA1c levels. A significant marginal association of insoluble dietary fibre intake with subsequent HbA1c levels was observed only when the HbA1c level was over 6·8 %. The associations appeared to be greater when the quantile levels of HbA1c were higher. The coefficient estimates were − 0·174 (95 % CI − 0·433, − 0·025) at the quantile of 0·60, − 0·200 (95 % CI − 0·306, − 0·008) at 0·70, − 0·221 (95 % CI − 0·426, − 0·117) at 0·80, and − 0·389 (95 % CI − 0·516, − 0·018) at 0·90. A similar pattern was observed for the associations of dietary glycaemic index (GI) value with HbA1c levels. In conclusion, the present results indicate that the associations of insoluble dietary fibre intake and GI value with subsequent HbA1c levels depend on glycaemic control status in Chinese diabetic patients. More studies are required to confirm our findings.

Objectives: Multiple single nucleotide polymorphisms (SNPs) have been identified as risk loci for type 2 diabetes (T2DM). This study was conducted to increase our understanding of the mechanisms through which three novel risk variants affect the risk of T2DM. Methods: 918 Chinese volunteers from Pudong New Area of Shanghai, China, were recruited in Oct-Dec, 2006. Collection of demographic and lifestyle characteristics, body measurements, bio-specimen collection and biochemistry assays were performed during the period. Genotyping of rs290487 at transcription factor 7-like 2 (TCF7L2), rs9465871 at cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1(CDKAL1) and rs1359790 at chromosome 13q31.1 were conducted using Taqman approach. Results: Genotypes of TCF7L2-rs290487, CDKAL1-rs9465871 and rs1359790 at 13q31.1 were not associated with metabolic syndrome or its components. While average levels of glycosylated hemoglobin A1c (HbA1c), fasting glucose, serum lipids and anthropometrics did not differ by genotypes of TCF7L2-rs290487 and rs1359790 at 13q31.1, HbA1c level varied significantly by genotypes of CDKAL1-rs9465871, particularly among women. After adjusting for age, women carrying C allele had a higher level of HbA1c than those bearing T allele, with each C allele linking to appropriate 0.1% increase of HbA1c level (P for trend=0.025). However, the difference was no longer significant after multiple comparison correction. Similar patterns were consistently observed regardless of levels of energy, dietary fat and average glycemic index intake (P for interaction >0.05). Conclusions: CDKAL1-rs9465871 may slightly affect glycemic phenotypes in non-diabetic Chinese women. Our results support the potential role of CDKAL1 gene in the regulation of insulin secretion.

Background The prevalence of metabolic syndrome (MS) has been increasing in China in recent years. The aim of this study is to estimate and compare the prevalence of MS among Chinese adults in Shanghai, one of the most economic developed areas in China, using definitions proposed by World Health Organization (WHO), National Cholesterol Education Program Adult Treatment Panel (modified ATP III) and International Diabetes Federation (IDF). Methods This cross-sectional study included 5,584 adults at age 20-79 randomly selected from Pudong New Area of Shanghai, China, through a three-stage sampling. All participants were interviewed in-person between April and July of 2008 to collect information on demographic and lifestyle characteristics. At the interview, anthropometry and blood pressure were measured and bio-specimens were collected. Results The prevalence estimates for the MS increased with age for each definition in men and women, but the estimates varied greatly between the definitions and by sex. The prevalence of the MS was higher in men (20.2%) than in women (18.7%) using WHO definition but this sex difference was reversed when using the modified ATP III (28.4% for men vs. 35.1% for women) and the IDF (15.9% for men vs. 26.7% for women) criteria. The most common metabolic disorder in this population was dyslipidaemia, regardless of the definition used. Substantial agreement, estimated using the kappa statistic, was found between the modified ATP III and IDF definition, whereas the lowest agreement was observed between the WHO and ATP III criteria. Conclusions The MS is highly prevalent among Chinese adults in Pudong New Area of Shanghai and the most prevalent component was dyslipidemia. These findings underscore the importance of prevention and control efforts for the MS in this area and the need for a unified predictive definition for the syndrome for use by clinical practitioners and public health agencies.

Background Dietary factors play an important role in glycemic control in diabetic patients. However, little is known about their effects among Chinese diabetic patients, whose diets are typically abundant in fiber and high in glycemic index (GI) values. Methodology/Principal Findings 934 patients with type 2 diabetes and 918 healthy volunteers from Pudong New Area, Shanghai, China, were interviewed during the period of Oct-Dec, 2006 to elicit demographic characteristics and lifestyle factors. Dietary habits were assessed using a validated food frequency questionnaire. Anthropometric measurements, bio-specimen collection and biochemical assays were conducted at the interview according to a standard protocol. In this population, diabetic patients consumed lower levels of energy and macronutrients but had higher levels of fasting plasma glucose (FPG), glycolated hemoglobin A1c (HbA1c), triglyceride and body mass index than healthy adults. While the average consumption levels of the nutrients among diabetic patients did not vary along duration of the disease, the average levels of FPG and HbA1c increased with increasing duration. Regardless of diabetes duration, HbA1c level was observed lower in patients having a higher fiber or lower GI intake. Compared with those with the lowest tertile intake of fiber, the adjusted odds ratios (ORs) for poor glycemic control reduced from 0.75 (95%CI: 0.54–1.06) to 0.51 (95%CI: 0.34–0.75) with increasing tertile intake (P for trend