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175 results on '"Xie, Jian-Hui"'

17. Analysis of Influencing Factors of Family Resilience in Children with Congenital Tibial Pseudoarthrosis

Author

Xie,Jian-Hui, Mei,Hai-Bo, Ouyang,Ya-Qi, Huang,Yuan, Liu,Kun, Zhu,Guang-Hui, Hou,Shu-Ting, and Wang,Lan-Ying

Subjects
Risk Management and Healthcare Policy, Health Policy, Public Health, Environmental and Occupational Health
Abstract

Jian-Hui Xie, Hai-Bo Mei, Ya-Qi Ouyang, Yuan Huang, Kun Liu, Guang-Hui Zhu, Shu-Ting Hou, Lan-Ying Wang Department of Orthopedics, Hunan Children’s Hospital, Changsha, 410007, People’s Republic of ChinaCorrespondence: Hai-Bo Mei, Department of Orthopedics, Hunan Children’s Hospital, No. 86 of Ziyuan Street, Yuhua District, Changsha, 410007, People’s Republic of China, Tel +86 139 7519 7731, Fax +86 731-85356666, Email mei_haibo@yeah.netAim: To investigate the status of the family resilience score of caregivers of children with congenital pseudarthrosis of the tibia (CPT) and analyse its influencing factors to provide a reference and basis for clinical formulation of a family resilience intervention programme.Methods: A total of 379 families of children with CPT were included in this study, which used a combination questionnaire to investigate the families of children with CPT. The researchers sent a link to the questionnaire to all eligible subjects to conduct a survey on the characteristics of families of children with CPT. Single factor analysis was used to compare the total scores of family resilience. Multiple linear regression was used to determine meaningful variables for single factor analysis.Results: The average family resilience score was 151.79 ± 30.79, the lowest score was 20 and the highest score was 231. The CPT usually occurred in unilateral limbs (37.63%). The payment methods of medical expenses were through a rural cooperative medical system (44.85%). The caregivers were mostly the mothers (62.80%) and caregivers were 31– 40 years old (62.27%). Most caregivers were farmers (30.34%). The average monthly income of the families in the past year was 1000– 5000 yuan (54.09%). There were significant differences in family resilience scores between caregivers’ working conditions (P = 0.039) and average monthly incomes in the past year (P = 0.008). The working conditions of caregivers and the average monthly income of families in the past year were the main factors affecting the family resilience of caregivers of children with CPT.Conclusion: The caregivers’ working conditions and the average monthly income of families were the influencing factors in the family resilience score.Keywords: congenital pseudarthrosis of the tibia, family resilience, family characteristics, influencing factor

Published
2021

22. Apoptosis induced by bruceine�D in human non‑small‑cell lung cancer cells involves mitochondrial ROS‑mediated death signaling

Author

Xie, Jian‑Hui, primary, Lai, Zheng‑Quan, additional, Zheng, Xing‑Han, additional, Xian, Yan‑Fang, additional, Li, Qian, additional, Ip, Siu‑Po, additional, Xie, You‑Liang, additional, Chen, Jian‑Nan, additional, Su, Zi‑Ren, additional, Lin, Zhi‑Xiu, additional, and Yang, Xiao‑Bo, additional

Published
2019
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23. Additional file 1: of Efficacy and indication optimization of Chinese medicine (Tiao-Chang Ke-Min granules) for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized controlled trial

Author

Li, Qian, Bei-Ping Zhang, Huang, Shao-Gang, Ouyang, Wen-Wei, Xie, Jian-Hui, Wen, Ze-Huai, and Yang, Xiao-Bo

Subjects
behavioral disciplines and activities
Abstract

Standard Protocol Items: Recommendations for Interventional Trial (SPIRIT) 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*. (DOC 119 kb)

Published
2018
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24. Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo

Author

Li, Cai-Lan, primary, Tan, Li-Hua, additional, Wang, Yong-Fu, additional, Luo, Chao-Dan, additional, Chen, Han-Bin, additional, Lu, Qiang, additional, Li, Yu-Cui, additional, Yang, Xiao-Bo, additional, Chen, Jian-Nan, additional, Liu, Yu-Hong, additional, Xie, Jian-Hui, additional, and Su, Zi-Ren, additional

Published
2019
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25. Curcumin’s Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB Pathway

Author

Zhang, Zhen-Biao, primary, Luo, Dan-Dan, additional, Xie, Jian-Hui, additional, Xian, Yan-Fang, additional, Lai, Zheng-Quan, additional, Liu, Yu-Hong, additional, Liu, Wei-Hai, additional, Chen, Jian-Nan, additional, Lai, Xiao-Ping, additional, Lin, Zhi-Xiu, additional, and Su, Zi-Ren, additional

Published
2018
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26. Novel Patchouli Alcohol Ternary Solid Dispersion Pellets Prepared by Poloxamers

Author

Liao, Jin-Bin, Liang, Yong-Zhuo, Chen, Yun-Long, Xie, Jian-Hui, Liu, Wei-Hai, Chen, Jian Nan, Lai, Xiao-Ping, and Su, Zi-Ren

Subjects
Poloxamers, Patchouli alcohol, Eutectic mixtures, Closed in-vitro dissolution test method, Original Article, Ternary solid dispersion pellets
Abstract

The present study investigates the possibility of using poloxamers as solubility and dissolution rate enhancing agents of poorly water soluble bioactive constituent patchouli alcohol (PA) that can be used for the preparation of immediate release pellets formulation. Two commercially available grades poloxamer 188 (P 188) and poloxamer 407 (P 407) were selected, and solid dispersions (SDs) containing different weight ratio of PA and poloxamers, and the combination of P 188 and P 407 as dispersing carriers of ternary solid dispersions (tSDs) were prepared by a low temperature melting method and solidified rapidly by dropping into the 10-15 °C condensing agent atoleine. Both PA/P 188 and PA/P 407 binary solid dispersions (bSDs) could remarkably promote the dissolution rate of PA, increasing approximately 16 times in bSDs with poloxamers in comparison with pure PA within 180 min. P188 contributed to a faster dissolution rate than P 407, however, P 407 had a better solubility. It is interesting to note that the incorporation of P 188 in PA/P 407 bSD pellets could strongly enhance the dissolution rate of PA. DSC and FTIR were used to explore the characteristics of PA-SD pellets. The enhancement of dissolution from the SDs may be attributed partly to the reduction in particle size in PA crystalline due to the formation of eutectic system with poloxamers. Moreover, a simple, accurate in-vitro dissolution test method for volatility drug was established, and the process of PA-SD pellets preparation was simple, rapid, cost effective, uncomplicated and potentially scalable.

Published
2015

33. Preparation of PDLC Films with Low-Threshold Voltage and High-CR

Author

谢建辉 Xie Jian-hui and 黄子强 Huang Zi-qiang

Subjects
chemistry.chemical_classification, Materials science, business.industry, Polymer, Electronic, Optical and Magnetic Materials, Threshold voltage, Butyl methacrylate, chemistry, Polymerization, Liquid crystal, Signal Processing, Optoelectronics, Contrast ratio, business, Instrumentation, Prepolymer, Voltage
Abstract

PDLC films were prepared by means of polymerization induced phase separation(PIPS),butyl methacrylate are mixed together with photosensitive prepolymer and nematic liquid crystal in certain ratio to reduce the anchoring energy of the surface between polymer and LC droplets,and to progress the U-T characteristics as well.The influence of different butyl methacrylate ratio on PDLC films was studied.The environment factors was optimized to prepare PDLC films with the best quality,low threshold-voltage and high CR(contrast ratio).It is demonstrated that the addition of butyl methacrylate do good to reduce the driving voltage.This paper also studied the influence of driving frequency on E-O characteristics of PDLC films.The experimental results show that the threshold voltage and saturable driving voltage of PDLC get larger with the increase of driving frequency and the E-O curve get gentle simultaneously.

Published
2011

37. Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice

Author

Huang, Yan-Feng, primary, Zhou, Jiang-Tao, additional, Qu, Chang, additional, Dou, Yao-Xing, additional, Huang, Qiong-Hui, additional, Lin, Zhi-Xiu, additional, Xian, Yan-Fang, additional, Xie, Jian-Hui, additional, Xie, You-Liang, additional, Lai, Xiao-Ping, additional, and Su, Zi-Ren, additional

Published
2017
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41. Effects of conservational tillage on water characteristics in dryland farm of central Gansu, Northwest China.

Author

PENG Zheng-kai, LI Ling-ling, XIE Jun-hong, KANG Cai-rui, ESSEL, Eunice, WANG Jin-bin, XIE Jian-hui, and SHEN Ji-cheng

Abstract

Productivity is low and unstable in dryland farms of central Gansu, Northwest China. Conservational tillage is an important way for the sustainable development of agriculture. The effects of different tillage measures on soil moisture infiltration, evaporation, crop yield and water use efficiency (WUE) were investigated in this study based on a long-term experiment since 2001 in Long-zhong. There were six treatments, i.e. conventional tillage with no straw (T), no-till with straw cover (NTS), no-till with no straw cover (NT), conventional tillage with straw incorporated (TS), conventional tillage with plastic mulch (TP), and no-till with plastic mulch (NTP), with annual rotation of spring wheat and pea. The results showed that compared with T, soil bulk density of NTS decreased and total porosity of soil increased significantly in wheat and pea land. Compared with conventional tillage, conservation tillage reduced soil infiltration rate in 0-5 cm in the pea field by 56.2%. Conservational tillage significantly increased soil saturated water conductivity in both wheat and pea lands. Compared with T, the saturated water conductivity in NTS was significantly increased by 52.8%-107.1%. Conservational tillage significantly reduced soil evaporation during growing season. Compared with T, the evapotranspiration of NTP, TP and NTS was significantly reduced by 14.4%-50.8%. The soil evaporation after rain was also decreased. Conservational tillage improved crop yield and water use efficiency by 9.5%-62.8% and 0.4%-50.9%, respectively. Therefore, conservational tillage could increase water use efficiency and crop yield in dryland farming area of central Gansu, Northwest China. [ABSTRACT FROM AUTHOR]

Published
2018
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43. Pharmacokinetic Interaction between Magnolol and Piperine in Rats

Author

Chen, Xiao-Ying, primary, Yang, Guang-Hua, additional, Li, Cai-Lan, additional, Yu, Xiu-Ting, additional, Wang, Xiu-Fen, additional, Zheng, Yi-Feng, additional, Xie, Jian-Hui, additional, Lai, Xiao-Ping, additional, Su, Zi-Ren, additional, Liang, Yong-Zhuo, additional, and Lin, Ji, additional

Published
2016
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46. Protective effects of silymarin on triptolide-induced acute hepatotoxicity in rats.

Author

Wang, Lan, Huang, Qiong-Hui, Li, Yong-Xian, Huang, Yan-Feng, Xie, Jian-Hui, Xu, Lie-Qiang, Dou, Yao-Xing, Su, Zi-Ren, Zeng, Hui-Fang, and Chen, Jian-Nan

Subjects
MICRORNA, SILYMARIN, MICROCYSTINS, HEPATOTOXICOLOGY, DISEASE progression
Abstract

Silymarin has been used in the treatment of a number of liver diseases for a long time, but its efficacy in preventing triptolide induced acute hepatotoxicity has not been reported previously. The present study aimed to assess the protective effect of silymarin against triptolide (TP)-induced hepatotoxicity in rats. Rats were orally administrated with silymarin (50, 100 and 200 mg/kg) for 7 days and received intraperitoneal TP (2 mg/kg) on the day 8. Hepatic injuries were comprehensively evaluated in terms of serum parameters, morphological changes, oxidative damage, inflammation and apoptosis. The results demonstrated that TP-induced increases in serum parameters, including alanine transaminase, aspartate aminotransferase, alkaline phosphatase, total cholesterol and γ-glutamyl transpeptidase, which were determined using a biochemical analyzer, and histopathological alterations and hepatocyte apoptosis as determined by hematoxylin and eosin and TUNEL staining, respectively, were prevented by silymarin pretreatment in a dose-dependent manner. TP-induced depletions in the activity of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, glutathione S-transferase and catalase, and glutathione levels, were also significantly reversed by silymarin, as determined using specific kits. Additionally, silymarin dose-dependently exhibited inhibitory effects on malonaldehyde content in the liver. The production of proinflammatory cytokines was investigated using ELISA kits, and the results demonstrated that silymarin dose-dependently inhibited the production of tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-10 and IL-1β in the liver. To determine the mechanism of silymarin, western blot analysis was performed to investigate the protein expression of phosphorylated (p)-p38 and p-c-Jun N-terminal kinase (JNK) of the TNF-α induced inflammatory response and apoptotic pathways. Silymarin significantly blocked p38 and JNK phosphorylation and activation. Additionally, the expression of the proapoptotic proteins cytochrome c, cleaved caspase-3 and Bcl-2-associated X was also reduced following treatment with silymarin, as determined by ELISA, western blotting and immunohistochemistry, respectively. In conclusion, silymarin was demonstrated to dose-dependently protect rat liver from TP-induced acute hepatotoxicity, with the high dose (200 mg/kg) achieving a superior effect. This protective effect may be associated with the improvement of antioxidant and anti-inflammatory status, as well as the prevention of hepatocyte apoptosis. Therefore, silymarin may have the potential to be applied clinically to prevent TP-induced acute hepatotoxicity. [ABSTRACT FROM AUTHOR]

Published
2018
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47. The gastroprotective effect of pogostone from Pogostemonis Herba against indomethacin-induced gastric ulcer in rats

Author

Chen, Xiao-Ying, primary, Chen, Hai-Ming, additional, Liu, Yu-Hong, additional, Zhang, Zhen-Biao, additional, Zheng, Yi-Feng, additional, Su, Zu-Qing, additional, Zhang, Xie, additional, Xie, Jian-Hui, additional, Liang, Yong-Zhuo, additional, Fu, Lu-Di, additional, Lai, Xiao-Ping, additional, Su, Zi-Ren, additional, and Huang, Xiao-Qi, additional

Published
2015
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49. Biological evaluation and molecular docking of baicalin and scutellarin as Helicobacter pylori urease inhibitors

Author

Yu, Xiao-Dan, primary, Zheng, Rong-Bo, additional, Xie, Jian-Hui, additional, Su, Ji-Yan, additional, Huang, Xiao-Qi, additional, Wang, Yong-Hong, additional, Zheng, Yi-Feng, additional, Mo, Zhi-Zhun, additional, Wu, Xiao-Li, additional, Wu, Dian-Wei, additional, Liang, Ye-er, additional, Zeng, Hui-Fang, additional, Su, Zi-Ren, additional, and Huang, Ping, additional

Published
2015
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