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176 results on '"Xu, Dan-Feng"'

1. Comparison of systematic and combined biopsy for the detection of prostate cancer

Author

Huang, Jin-Lun, primary, Huang, Da, additional, Chun, Tsun-Tsun, additional, Yao, Chi, additional, Zhan, Yong-Le, additional, Ruan, Xiao-Hao, additional, Lai, Terence Chun-Ting, additional, Tsang, Chiu-Fung, additional, Pang, Karl-Ho, additional, Ng, Ada Tsui-Lin, additional, Xu, Dan-Feng, additional, Ho, Brian Sze-Ho, additional, and Na, Rong, additional

Published
2024
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4. Supplementary Figures and Figure Legends from Reciprocal Network between Cancer Stem-Like Cells and Macrophages Facilitates the Progression and Androgen Deprivation Therapy Resistance of Prostate Cancer

Author

Huang, Hai, primary, Wang, Chao, primary, Liu, Fei, primary, Li, Hui-Zhen, primary, Peng, Guang, primary, Gao, Xu, primary, Dong, Ke-Qin, primary, Wang, Hong-Ru, primary, Kong, De-Pei, primary, Qu, Min, primary, Dai, Li-He, primary, Wang, Kai-Jian, primary, Zhou, Zhe, primary, Yang, Jun, primary, Yang, Ze-Yu, primary, Cheng, Yan-Qiong, primary, Tian, Qin-Qin, primary, Liu, Dan, primary, Xu, Chuan-Liang, primary, Xu, Dan-Feng, primary, Cui, Xin-Gang, primary, and Sun, Ying-Hao, primary

Published
2023
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5. Supplementary Tables (S1-S8) from Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer

Author

Wang, Chao, primary, Peng, Guang, primary, Huang, Hai, primary, Liu, Fei, primary, Kong, De-Pei, primary, Dong, Ke-Qin, primary, Dai, Li-He, primary, Zhou, Zhe, primary, Wang, Kai-Jian, primary, Yang, Jun, primary, Cheng, Yan-Qiong, primary, Gao, Xu, primary, Qu, Min, primary, Wang, Hong-Ru, primary, Zhu, Feng, primary, Tian, Qin-Qin, primary, Liu, Dan, primary, Cao, Li, primary, Cui, Xin-Gang, primary, Xu, Chuan-Liang, primary, Xu, Dan-Feng, primary, and Sun, Ying-Hao, primary

Published
2023
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6. Supplementary Tables from Reciprocal Network between Cancer Stem-Like Cells and Macrophages Facilitates the Progression and Androgen Deprivation Therapy Resistance of Prostate Cancer

Author

Huang, Hai, primary, Wang, Chao, primary, Liu, Fei, primary, Li, Hui-Zhen, primary, Peng, Guang, primary, Gao, Xu, primary, Dong, Ke-Qin, primary, Wang, Hong-Ru, primary, Kong, De-Pei, primary, Qu, Min, primary, Dai, Li-He, primary, Wang, Kai-Jian, primary, Zhou, Zhe, primary, Yang, Jun, primary, Yang, Ze-Yu, primary, Cheng, Yan-Qiong, primary, Tian, Qin-Qin, primary, Liu, Dan, primary, Xu, Chuan-Liang, primary, Xu, Dan-Feng, primary, Cui, Xin-Gang, primary, and Sun, Ying-Hao, primary

Published
2023
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7. Supplementary Figures and Legends (S1-S6) from Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer

Author

Wang, Chao, primary, Peng, Guang, primary, Huang, Hai, primary, Liu, Fei, primary, Kong, De-Pei, primary, Dong, Ke-Qin, primary, Dai, Li-He, primary, Zhou, Zhe, primary, Wang, Kai-Jian, primary, Yang, Jun, primary, Cheng, Yan-Qiong, primary, Gao, Xu, primary, Qu, Min, primary, Wang, Hong-Ru, primary, Zhu, Feng, primary, Tian, Qin-Qin, primary, Liu, Dan, primary, Cao, Li, primary, Cui, Xin-Gang, primary, Xu, Chuan-Liang, primary, Xu, Dan-Feng, primary, and Sun, Ying-Hao, primary

Published
2023
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15. [Corrigendum] SMC1A promotes growth and migration of prostate cancer in vitro and in vivo

Author

Pan, Xiu-Wu, primary, Gan, Si-Shun, additional, Ye, Jian-Qing, additional, Fan, Ying-Hui, additional, Hong, Yi, additional, Chu, Chuan-Min, additional, Gao, Yi, additional, Li, Lin, additional, Liu, Xi, additional, Chen, Lu, additional, Huang, Yi, additional, Xu, Hong, additional, Ren, Ji-Zhong, additional, Yin, Lei, additional, Qu, Fa-Jun, additional, Huang, Hai, additional, Cui, Xin-Gang, additional, and Xu, Dan-Feng, additional

Published
2021
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18. Prostate Health Index (phi) and its derivatives predict Gleason score upgrading after radical prostatectomy among patients with low-risk prostate cancer.

Author

Yan, Jia-Qi, Huang, Da, Huang, Jing-Yi, Ruan, Xiao-Hao, Lin, Xiao-Ling, Fang, Zu-Jun, Gao, Yi, Jiang, Hao-Wen, Wu, Yi-Shuo, Na, Rong, and Xu, Dan-Feng

Abstract

To analyze the performance of the Prostate Health Index (phi) and its derivatives for predicting Gleason score (GS) upgrading between prostate biopsy and radical prostatectomy (RP) in the Chinese population, an observational, prospective RP cohort consisting of 351 patients from two medical centers was established from January 2017 to September 2020. Pathological reclassification was determined by the Gleason Grade Group (GG). The area under the receiver operating characteristic curve (AUC) and logistic regression (LR) models were used to evaluate the predictive performance of predictors. In clinically low-risk patients with biopsy GG ≤2, phi (odds ratio [OR] = 1.80, 95% confidence interval [95% CI]: 1.14–2.82, P = 0.01) and its derivative phi density (PHID; OR = 2.34, 95% CI: 1.30–4.20, P = 0.005) were significantly associated with upgrading to GG ≥3 after RP, and the results were confirmed by multivariable analysis. Similar results were observed in patients with biopsy GG of 1 for the prediction of upgrading to RP GG ≥2. Compared to the base model (AUC = 0.59), addition of the phi or PHID could provide additional predictive value for GS upgrading in low-risk patients (AUC = 0.69 and 0.71, respectively, both P < 0.05). In conclusion, phi and PHID could predict GS upgrading after RP in clinically low-risk patients. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Prostate volume does not provide additional predictive value to prostate health index for prostate cancer or clinically significant prostate cancer: results from a multicenter study in China

Author

Xu, Dan-Feng, primary, Na, Rong, primary, Huang, Da, additional, Wu, Yi-Shuo, additional, Ye, Ding-Wei, additional, Qi, Jun, additional, Liu, Fang, additional, Helfand, BrianT, additional, Zheng, SiqunL, additional, Ding, Qiang, additional, Xu, Jian-Feng, additional, and Sun, Ying-Hao, additional

Published
2020
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31. Characterization of progression-related alternative splicing events in testicular germ cell tumors.

Author

Zhang, Chuan-Jie, Li, Zong-Tai, Shen, Kan-Jie, Chen, Lu, Xu, Dan-Feng, and Gao, Yi

Abstract

Accumulating evidence supports the significance of aberrant alternative splicing (AS) events in cancer; however, genome-wide profiling of progression-free survival (PFS)-related AS events in testicular germ cell tumors (TGCT) has not been reported. Here, we analyzed high-throughput RNA-sequencing data and percent-spliced-in values for 150 patients with TGCT. Using univariate and multivariate Cox regression analysis and a least absolute shrinkage and selection operator method, we identified the top 15 AS events most closely associated with disease progression. A risk-associated AS score (ASS) for the 15 AS events was calculated for each patient. ASS, pathological stage, and T stage were significantly associated with disease progression by univariate analysis, but only ASS and pathological stage remained significant by multivariate analysis. The ability of these variables to predict 5-year progression was assessed using receiver operating characteristic curve analysis. ASS had stronger predictive value than a combination of age, pathological stage, and T stage (area under the curve = 0.899 and 0.715, respectively). Furthermore, Kaplan–Meier analysis of patients with low and high ASS demonstrated that high ASS was associated with significantly worse PFS than low ASS (P = 1.46 × 10−7). We also analyzed the biological functions of the PFS-related AS-related genes and found enrichment in pathways associated with DNA repair and modification. Finally, we identified a regulatory network of splicing factors with expression levels that correlated significantly with AS events in TGCT. Collectively, this study identifies a novel method for risk stratification of patients and provides insight into the molecular events underlying TGCT. [ABSTRACT FROM AUTHOR]

Published
2021
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34. Reciprocal Network between Cancer Stem-Like Cells and Macrophages Facilitates the Progression and Androgen Deprivation Therapy Resistance of Prostate Cancer

Author

Huang, Hai, primary, Wang, Chao, additional, Liu, Fei, additional, Li, Hui-Zhen, additional, Peng, Guang, additional, Gao, Xu, additional, Dong, Ke-Qin, additional, Wang, Hong-Ru, additional, Kong, De-Pei, additional, Qu, Min, additional, Dai, Li-He, additional, Wang, Kai-Jian, additional, Zhou, Zhe, additional, Yang, Jun, additional, Yang, Ze-Yu, additional, Cheng, Yan-Qiong, additional, Tian, Qin-Qin, additional, Liu, Dan, additional, Xu, Chuan-Liang, additional, Xu, Dan-Feng, additional, Cui, Xin-Gang, additional, and Sun, Ying-Hao, additional

Published
2018
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37. Non-functional paraganglioma of the urinary bladder: a case report

Author

Gao Yi, Liu Yu-Shan, Chen Ming, Xu Dan-Feng, and Cui Xin-Gang

Subjects
Medicine
Abstract

Abstract Introduction Paragangliomas that originate from the urinary bladder are extremely rare. In most series, bladder paragangliomas often cause micturitional attacks. Treatment modalities include transurethral resection and cystectomy (partial or total). Prognosis of bladder paraganglioma is similar to that of adrenal pheochromocytoma. Case presentation A 55-year-old Chinese woman presenting with the sole complaint of lower abdominal pain for one month was admitted to our hospital. Ultrasound and computed tomography revealed a mass on the dome of the bladder measuring 4.0 × 3.0 cm. The tumor was completed removed by laparoscopic partial cystectomy. Histological examination of the tumor indicated paraganglioma of the urinary bladder. The clinical features, diagnosis, management and pathological findings of paraganglioma of the urinary bladder are discussed. Conclusions Bladder paraganglioma should be considered as a differential diagnosis to neoplasm in the urinary bladder, although there is no characteristic symptom. Laparoscopic partial cystectomy may be the first choice in treating paraganglioma of the urinary bladder, offering several advantages such as less invasion, rapid recovery and early discharge from the hospital.

Published
2010
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38. Prostate volume does not provide additional predictive value to prostate health index for prostate cancer or clinically significant prostate cancer: results from a multicenter study in China.

Author

Huang, Da, Wu, Yi-Shuo, Ye, Ding-Wei, Qi, Jun, Liu, Fang, Helfand, Brian, Zheng, Siqun, Ding, Qiang, Xu, Dan-Feng, Na, Rong, Xu, Jian-Feng, and Sun, Ying-Hao

Abstract

To evaluate whether prostate volume (PV) would provide additional predictive utility to the prostate health index (phi) for predicting prostate cancer (PCa) or clinically significant prostate cancer, we designed a prospective, observational multicenter study in two prostate biopsy cohorts. Cohort 1 included 595 patients from three medical centers from 2012 to 2013, and Cohort 2 included 1025 patients from four medical centers from 2013 to 2014. Area under the receiver operating characteristic curves (AUC) and logistic regression models were used to evaluate the predictive performance of PV-based derivatives and models. Linear regression analysis showed that both total prostate-specific antigen (tPSA) and free PSA (fPSA) were significantly correlated with PV (all P < 0.05). [-2]proPSA (p2PSA) was significantly correlated with PV in Cohort 2 (P< 0.001) but not in Cohort 1 (P= 0.309), while no significant association was observed between phi and PV. When combining phi with PV, phi density (PHID) and another phi derivative (PHIV, calculated as phi/PV0.5) did not outperform phi for predicting PCa or clinically significant PCa in either Cohort 1 or Cohort 2. Logistic regression analysis also showed that phi and PV were independent predictors for both PCa and clinically significant PCa (all P < 0.05); however, PV did not provide additional predictive value to phi when combining these derivatives in a regression model (all models vs phi were not statistically significant, all P > 0.05). In conclusion, PV-based derivatives (both PHIV and PHID) and models incorporating PV did not improve the predictive abilities of phi for either PCa or clinically significant PCa. [ABSTRACT FROM AUTHOR]

Published
2020
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39. Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer

Author

Wang, Chao, primary, Peng, Guang, additional, Huang, Hai, additional, Liu, Fei, additional, Kong, De-Pei, additional, Dong, Ke-Qin, additional, Dai, Li-He, additional, Zhou, Zhe, additional, Wang, Kai-Jian, additional, Yang, Jun, additional, Cheng, Yan-Qiong, additional, Gao, Xu, additional, Qu, Min, additional, Wang, Hong-Ru, additional, Zhu, Feng, additional, Tian, Qin-Qin, additional, Liu, Dan, additional, Cao, Li, additional, Cui, Xin-Gang, additional, Xu, Chuan-Liang, additional, Xu, Dan-Feng, additional, and Sun, Ying-Hao, additional

Published
2018
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41. Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells

Author

Chen, Ming, primary, Lv, Jian-Min, additional, Ye, Jian-Qing, additional, Cui, Xin-Gang, additional, Qu, Fa-Jun, additional, Chen, Lu, additional, Liu, Xi, additional, Pan, Xiu-Wu, additional, Li, Lin, additional, Huang, Hai, additional, Yang, Qi-Wei, additional, Chen, Jie, additional, Wang, Lin-Hui, additional, Gao, Yi, additional, and Xu, Dan-Feng, additional

Published
2017
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44. SMC1A promotes growth and migration of prostate cancer in vitro and in vivo

Author

Pan, Xiu-Wu, primary, Gan, Si-Shun, additional, Ye, Jian-Qing, additional, Fan, Ying-Hui, additional, Hong, Yi, additional, Chu, Chuan-Min, additional, Gao, Yi, additional, Li, Lin, additional, Liu, Xi, additional, Chen, Lu, additional, Huang, Yi, additional, Xu, Hong, additional, Ren, Ji-Zhong, additional, Yin, Lei, additional, Qu, Fa-Jun, additional, Huang, Hai, additional, Cui, Xin-Gang, additional, and Xu, Dan-Feng, additional

Published
2016
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45. EIF3D silencing suppresses renal cell carcinoma tumorigenesis via inducing G2/M arrest through downregulation of Cyclin B1/CDK1 signaling

Author

PAN, XIU-WU, primary, CHEN, LU, additional, HONG, YI, additional, XU, DAN-FENG, additional, LIU, XI, additional, LI, LIN, additional, HUANG, YI, additional, CUI, LI-MING, additional, GAN, SI-SHUN, additional, YANG, QI-WEI, additional, HUANG, HAI, additional, QU, FA-JUN, additional, YE, JIAN-QING, additional, WANG, LIN-HUI, additional, and CUI, XIN-GANG, additional

Published
2016
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46. Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation

Author

Huang, Yi, primary, Pan, Xiu-Wu, additional, Li, Lin, additional, Chen, Lu, additional, Liu, Xi, additional, Lu, Jian-Lei, additional, Zhu, Xiao-Mei, additional, Huang, Hai, additional, Yang, Qi-Wei, additional, Ye, Jian-Qing, additional, Gan, Si-Shun, additional, Wang, Lin-Hui, additional, Hong, Yi, additional, Xu, Dan-Feng, additional, and Cui, Xin-Gang, additional

Published
2016
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