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18 results on '"Xu, Jiyan"'

8. Building the Association Catalog for Books Based on Association Linked Network

Author

Wei, Xiao, Wu, Wei, Xu, Jiyan, Xu, Zheng, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Luo, Xiangfeng, editor, Cao, Yiwei, editor, Yang, Bo, editor, Liu, Jianxun, editor, and Ye, Feiyue, editor

Published
2011
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12. Research on Networked Manufacturing Model and Information Management

Author

Hu Dachao, Zhang Qiling, Zhu Yuping, He Yu'an, and Xu Jiyan

Subjects
Information management, Computer-integrated manufacturing, Computer science, Process (engineering), business.industry, Integrated Computer-Aided Manufacturing, Server, Manufacturing, Numerical control, Advanced manufacturing, business, Manufacturing engineering
Abstract

Networked manufacturing (NM) is an advanced manufacturing method. The profound influence of networked manufacturing for the global industry is taking place. Based on the analysis of the requirements and technology driving forces of the networked manufacturing, the basic features and connotation of NM based on workshop NC equipment are discussed. The structure and mode of a networked manufacturing system among workshop NC (Numerical Control) equipment are presented. Aiming at the status of present Numerical Control (NC) or Computer Numerical Control (CNC) equipment of the manufacturing industry, several typical DNC communication schemes for workshops are proposed. Finally, we take the prototype system as an example to illustrate the operation process of NM based on workshop equipment.

Published
2008

18. Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice.

Author

Liu Y, Han X, Su Y, Zhou Y, Xu M, Xu J, Ma Z, Gu X, and Xia T

Abstract

Abstract: Postoperative cognitive dysfunction is a severe complication of the central nervous system that occurs after anesthesia and surgery, and has received attention for its high incidence and effect on the quality of life of patients. To date, there are no viable treatment options for postoperative cognitive dysfunction. The identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future research. To identify the signaling mechanisms contributing to postoperative cognitive dysfunction, we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset, which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus 3 days after tibial fracture. The dataset was enriched in genes associated with the biological process "regulation of immune cells," of which Chill was identified as a hub gene. Therefore, we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fracture surgery. Mice were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 1 24 hours post-surgery, and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning tests. In addition, protein expression levels of proinflammatory factors (interleukin-1β and inducible nitric oxide synthase), M2-type macrophage markers (CD206 and arginase-1), and cognition-related proteins (brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B) were measured in hippocampus by western blotting. Treatment with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment, downregulated interleukin-1β and nducible nitric oxide synthase expression, and upregulated CD206, arginase-1, pNR2B, and brain-derived neurotropic factor expression compared with vehicle treatment. Intraperitoneal administration of the specific ERK inhibitor PD98059 diminished the effects of recombinant chitinase-3-like protein 1. Collectively, our findings suggest that recombinant chitinase-3-like protein 1 ameliorates surgery-induced cognitive decline by attenuating neuroinflammation via M2 microglial polarization in the hippocampus. Therefore, recombinant chitinase-3-like protein 1 may have therapeutic potential for postoperative cognitive dysfunction., (Copyright © 2024 Copyright: © 2024 Neural Regeneration Research.)

Published
2024
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