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To accurately extract human body contours, a method for complex background human body contour extraction based on the MINet model was proposed. Front-view and side-view human images were captured, and corresponding mask images were annotated. Diverse complex backgrounds were matched with portraits to create a dataset of 2 860 portraits across various scenes. Using a transfer learning mechanism, the MINet salient object detection model was optimized to extract human body contours. The human contour extraction effects of the transfer learning- based MINet model were compared with the original model, the U2Net salient object detection model, the Media- pipe human contour extraction algorithm, and a traditional threshold-based segmentation algorithm. The results show that the transfer learning-based MINet model demonstrates optimal performance in human body contour extraction, with precision, accuracy, recall, and the composite metric F1 reaching 0.998, 0.987, 0.992, and 0.990, respectively, closely resembling the annotated mask images. This method offers a cost-effective, scalable, and fast approach to extract human body contours from images, providing an effective technique for photo measurement in remote clothing customization. [ABSTRACT FROM AUTHOR]

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Textile motion in a front-loading washer has been characterized via video capturing, and a processing system developed based on image geometric moment. Textile motion significantly contributes to the mass transfer of the wash solution in porous materials, particularly in the radial direction (perpendicular to the rotational axis of the inner drum). In this paper, the velocity profiles and residence time distributions of tracer textiles have been investigated to characterize the textile dynamics in a front-loading washer. The results show that the textile motion varies significantly with the water volume and rotational speed, and that the motion path follows certain patterns. Two regions are observed in the velocity plots: a passive region where the textile moves up with low velocity and an active region where the textile falls down with relatively high speed. A stagnant area in the residence time profile is observed. This corresponds to the passive region in the velocity profile. The stagnant area affects the mechanical action, thus influencing washing efficiency and textile performance. The findings on textile dynamics will help in the development of better front-loading washers. [ABSTRACT FROM AUTHOR]

Traditional computer vision methods cannot match human performance well on fabric smoothness classification, as this is a subjective assessment based on sparse, comprehensive and low-cost visual perception. This paper reports a new assessment method of fabric smoothness appearance, including feature designing and wrinkle classification. A multidimensional feature was designed by generalizing vector quantization of dense scale-invariant feature transform (SIFT) descriptors for sparse coding and max pooling. Sparse coding provides clear understanding about the receptive fields of visual neurons and can build a codebook from the low features. A one-against-rest linear support vector machine (SVM) was utilized to classify the nine grades of smoothness and quantized to level 0.1 by space distance. Results showed that the proposed approach achieved remarkable classification accuracy in comparison with Bag-of-Feature (BOF) and Spatial Pyramid Matching (SPM) algorithms. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to evaluate the effect of therapeutic ultrasound (TUS) on dermal delivery and therapeutic effect for frostbite of nanogel containing triterpenoids isolated fromGanoderma lucidum(GLT). Methods: GLT nanosuspension (GLT-NS) was prepared by high pressure homogenization and then suitably gelled to obtain GLT nanogel. The effects of TUS on GLT releasing from GLT nanogel and GLT permeation through the excised rat abdominal skin were evaluated. Moreover, a comparative study was also undertaken between different treatments of frostbite in rats: topical application of GLT nanogel (alone), TUS (alone) and GLT nanogel + TUS (plus). Results: In thein vitrorelease study, TUS has no influence on drug release from the nanogel. Results of thein vitrotransdermal study indicated that TUS significantly increased the cumulative amount of GLT permeating across and into the skin and reduced the lag time in comparison with passive diffusion (without TUS). As evidenced by the significant increase of wound healing area and the improvement in frostbite, TUS applied with simultaneous treatment method could improve the therapeutic effect of the GLT nanogel for frostbite. Conclusion: The present study revealed that the TUS can be effectively used to actively enhance topical delivery of GLT from nanogel and improve the therapeutic effect for frostbite in rats. [ABSTRACT FROM PUBLISHER]

Generally, image-based evaluation on the performance of textile appearance such as smoothness and pilling was interfered by fabric pattern, color, and illumination. In this paper, a new method was used to reconstruct a 3D surface of fabric based on image’s features which could eliminate the influence of surface texture. Concretely, two parallel-placed digital cameras were calibrated based on planar pattern and the captured binocular images were rectified through epipolar line. The feature points of binocular images were extracted by the Scale-Invariant Feature Transform which could detect and describe local features of images was insensitive to transformations and colors. Based on the similarity in descriptor and a geometric constraint, pairs of sparse matched points were detected and were regarded as the source points of diffusion regions. Remaining points of the overlapped areas were then matched based on normalized cross correlation in “best-first” principle. The outputs of the system included a surface disparity map and the space coordinate of fabric. The experimental results showed that the high-fidelity 3D fabric surface reconstructed by the new method was insusceptible to fabric structures, colors, fiber contents, etc., providing available solution for the further inspection on the performance of textile appearance. [ABSTRACT FROM PUBLISHER]

Cucurbitacin B (Cu B), a potent anti-cancer agent, suffers with the problems of water-insoluble, gastrointestinal side effects and non-specific toxicity via oral administration and drawbacks in patient's compliance and acceptance through injections. An integration of nanoscale carriers with mucoadhesive buccal films drug delivery system would resolve these issues effectively with greater therapeutic benefits and clinical significance. Thus, the drug loaded mucoadhesive buccal film was developed and characterized in this study and the carboxymethyl chitosan (CCS) was chosen as a bioadhesive polymer, glycerol was chosen as a plasticizer and phospholipid-bile salts-mixed micelles (PL-BS-MMs) was selected as the nanoscale carriers. The CCS-films containing Cu B loaded PL-SDC-MMs was evaluated for the mechanical properties, mucoadhesion properties, in vitro water-uptake, in vitro release and morphological properties, respectively. The optimal CCS-films containing Cu B loaded PL-SDC-MMs was easily reconstituted in a transparent and clear solution with spherical micelles in the submicron range. The in vivo study revealed a greater and more extended release of Cu B from nanoscale CCS-films compared to that from a conventional CCS films (C-CCS-films) and oral marketed tablet (Hulusupian). The absorption of Cu B from CCS-films containing Cu B loaded PL-SDC-MMs resulted in 2.69-fold increased in bioavailability as compared to conventional tablet formulation and 10.46 times with reference to the C-CCS-films formulation. Thus, this kind of mucoadhesive buccal film might be an alternative safe route for delivery of Cu B with better patient compliance and higher bioavailability for the treatments. [ABSTRACT FROM AUTHOR]

Objective: Zika virus disease is an acute infectious disease caused by Zika virus transmitted through Aedes mosquitoes. To explore the therapeutic effect of integrated traditional Chinese and Western Medicine for Zika virus disease, the treatment process of the first imported case in China was reviewed., Methods: The first imported Zika virus disease in China was admitted to Ganxian People's Hospital in Jiangxi Province on February 6th, 2016, and the patient received isolation treatment for 9 days and cured later. The effect of antiviral treatments including Xiyanping injection was evaluated based on clinical diagnosis and treatment process of the patient., Results: A 34-year old male patient was admitted with chief complaint of fever for 9 days, orbital pain and itching rash for 4 days on February 6th, 2016. (1) Epidemiological characteristics: the patient was bitted by mosquitoes during his business trip in Venezuela since January 1st, where Zika virus disease was spreading. On January 20th he had dizziness without fever, and the symptom disappeared after taking medicines without details. Paroxysmal dizziness, chills and mild fever without myalgia was experienced on January 28th. On February 3rd small red rash appeared in the neck, spreading to anterior part of chest, limbs and trunk, and the fever, fatigue, nausea was continued, and a new symptom of paroxysmal pain in back of ears and orbits appeared, during which he had not go to hospital. The symptoms relieved on February 4th. He returned to Ganxian County on February 5th, he had yellow stool 3 times with normal temperature, without abdominal pain, and red rash still appeared in the neck. He went to Ganxian People's Hospital on February 6th, 2016. (2) Clinical manifestation: the vital signs showed a temperature of 36.8?centigrade, a pulse rate of 80 bpm, a respiratory rate of 20 bpm, and a blood pressure of 110/70 mmHg (1 mmHg = 0.133 kPa). It was showed by physical examination that red rash appeared in the neck, and no superficial enlarged lymph nodes were found. Bilateral conjunctival congestion was obvious, physiological reflex existed and pathological reflex was not found. (3) Auxiliary lab test and examination: no abnormal finding were revealed throughout examination and laboratory tests, including routine blood test, liver function, renal function, serum myocardial enzyme, electrolyte, blood sugar, C-reactive protein (CRP), troponin I (TnI), and procalcitonin (PCT), except slight prolongation in activated partial thromboplastin time (APTT, 38.6 s) on February 6th; and slightly dense shadow in left lung in lung CT scan, considering inflammatory changes and slight emphysema (especially in the left lower lung) as well as bilateral renal calculus on February 8th. No significant abnormalities were found in electrocardiogram and B ultrasound test of liver, spleen, and pancreas. (4) Virus confirmation: Zika virus nucleic acid was positive reported by Jiangxi Province Center for Disease Control and Prevention (CDC) on February 7th and Chinese CDC on February 9th, respectively, though Dengue virus were negative reported by Ganzhou CDC on February 6th. Right after the first diagnosis, anyone who had been in close contact with the patient received medical monitoring. (5)Treatment process: on February 6th, symptomatic treatment was prescribed since admitted into the infectious isolation wards and daily intravenous drip of Xiyanping injection 250 mg was prescribed for antiviral therapy. On February 7th, the patient had no fever, with occasional chills, neck rash was disappeared, orbital pain relieved and bilateral conjunctival hyperemia range was paler and narrowed, and his condition improved. Ibuprofen was administered for defervesce 3 times a day when his temperature reached to 37.5?centigrade at 16:00. On February 8th, the patient had no fever, times of chills was significantly reduced, without myalgia and rash, orbital pain and conjunctival hyperemia further recovered. On February 9th, bilateral eyes slightly tingling, mild conjunctival congestion, no fever chills or other discomfort was found. The chloramphenicol eye drops was prescribed for relieving sting pain with conjunctival congestion twice a day as recombinant human interferon alpha eye drops was out of store. The patient was comfortable from February 11th to February 13th. Blood and urine test for Zika were reported negative by the Chinese CDC and Jiangxi Province CDC. Because all the discharge criteria were satisfied, the patient was discharged on February 14th., Conclusions: At present, there is no specific effective drug to prevent and treat Zika virus disease effectually. After receiving symptomatic treatment and antiviral treatments including Xiyanping injection, the patient's symptoms were relieved. Zika virus nucleic acid in blood and urine was negative. The patient was discharged. Combination of traditional Chinese medicine and Western medicine maybe a good method to prevent and treat Zika virus disease.

To established an effective GC-MS /MS method for the contents determination of the residual DEHP in injection equipment, and investigate the effect of the pretreatment on the measurement. To simulate the clinical conditions of use, under the condition of 37 degrees C balance extraction, extract liquor by chloroform extraction, then the extract followed by analysis of GC-MS /MS. The method was simple, rapid, sensitive and accurate. The limits of quantitation (LOQ, S/N = 5) of cyclohexanone was 0.075 μg/mL, The spiked average recoveries ranged from 92% to 98%. The relative standard deviations (RSDs) of the method ranged from 1.01% to 1.61%, The method was simple, fast, sensitive and accurate, and may serve as a mass control method for residual DEHP in injection equipment.

An effective GC method was established for contents determination of the residual solvent of cyclohexanone in infusion sets for single use. The cyclohexanone in infusion sets for single use products were extracted with circular pump, using ethylalcohol as the extraction solven, then the extract followed by analysis of gas chromatography-tandem mass spectrometry. The method was simple, rapid, sensitive and accurate, Cyclohexanone showed good linearity in the range of (5.5-190.9) μg/mL, the correlation coefficient was 0.999 0, the detection limit (S/N = 3) was 0.133 μg/mL and limits of quantitation (S/N = 10) was 1.33 μg/mL. The spiked average recoveries ranged from 98% to 99%. The relative standard deviations (RSDs) of the method ranged from 1.03% to 1.98%. The method was simple, fast, sensitive and accurate, and may serve as a mass control method for residual cyclohexanone in disposable infusion sets for single use.