Search

Your search keyword '"Xu, Wei-ping"' showing total 170 results
Start Over Author "Xu, Wei-ping"
170 results on '"Xu, Wei-ping"'

7. Di(2-ethylhexyl) phthalate mediates oxidative stress and activates p38MAPK/NF-kB to exacerbate diabetes-induced kidney injury in vitro and in vivo models.

Author

Ding, Wen-Jie, Huang, Shou-Lin, Huang, Song, Xu, Wei-Ping, and Wei, Wei

Subjects
KIDNEY injuries, OXIDATIVE stress, HIGH-fat diet, PHTHALATE esters, STREPTOZOTOCIN, INFLAMMATION
Abstract

Plasticizer di(2-ethylhexyl) phthalate (DEHP) is employed to make polyethylene polymers. Some studies in epidemiology and toxicology have shown that DEHP exposure over an extended period may be hazardous to the body, including nephrotoxicity, and aggravate kidney damage in the context of underlying disease. However, studies on the toxicity of DEHP in diabetes-induced kidney injury have been rarely reported. Using a high-fat diet (HFD) and streptozotocin (STZ, 35 mg/kg)-induced kidney injury in mice exposed to various daily DEHP dosages, we explored the impacts of DEHP on diabetes-induced kidney injury. We discovered that DEHP exposure significantly promoted the renal inflammatory response and oxidative stress in mice, with increased P-p38 and P-p65 protein levels and exacerbated the loss of podocin. The same findings were observed in vitro after stimulation of podocytes with high glucose (30 mmol/L) and exposure to DEHP. Our results suggest that DEHP exacerbates diabetes-induced kidney injury by mediating oxidative stress and activating p38MAPK/NF-κB. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

16. Lead‐Free Halide CsAg2I3 with 1D Electronic Structure and High Stability for Ultraviolet Photodetector.

Author

Yao, Ming‐Ming, Zhang, Qun, Wang, Dan, Chen, Ren‐li, Yin, Yi‐Chen, Xia, Jun, Tang, Heng, Xu, Wei‐Ping, and Yu, Shu‐Hong

Subjects
STRUCTURAL stability, ELECTRONIC structure, PHOTODETECTORS, LEAD halides, STOKES shift, PEROVSKITE
Abstract

Lead halide perovskites have gained extensive attention in the photodetectors (PDs) field, but the problems of intrinsic toxicity and poor stability still hamper their practical applications. Furthermore, ultraviolet (UV) PDs have rarely been explored due to challenges, including the lack of suitable materials and the costly and complicated fabrication processes. In order to solve the above problems, herein it is reported a novel all‐inorganic lead‐free halide CsAg2I3 single crystal (SC) with pure phase and high quality. This CsAg2I3 SC shows ultra‐stable crystal structure, steady chemical properties, and good optical properties, and it can be stable up to 893 K. Its 1D crystal structure and soft crystal lattice support the formation of self‐trapped excitons, leading to a broadband emission at 610 nm with a large Stokes shift of 315 nm (2.23 eV). The strong absorption for UV light combined with direct bandgap, large Stokes shift, and ultra‐high stability promises an environment‐friendly, low‐cost, and high‐performance UV PD based on the 1D all‐inorganic silver (I) halides. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

24. Improving Lead‐Free Double Perovskite Cs2NaBiCl6 Nanocrystal Optical Properties via Ion Doping.

Author

Yao, Ming‐Ming, Wang, Li, Yao, Ji‐Song, Wang, Kun‐Hua, Chen, Chen, Zhu, Bai‐Sheng, Yang, Jun‐Nan, Wang, Jing‐Jing, Xu, Wei‐Ping, Zhang, Qun, and Yao, Hong‐Bin

Subjects
OPTICAL properties, QUANTUM dot synthesis, LEAD halides, IONS, NANOCRYSTALS
Abstract

The exploration of lead‐free halide perovskite nanocrystals (NCs) with intriguing optical properties is highly desirable owing to the toxicity and instability of lead halide perovskite NCs. Here, a new kind of uniform lead‐free double perovskite Cs2NaBiCl6 NCs are reported as versatile hosts to accommodate ionic dopants for improving optical properties especially the photoluminescence (PL). In contrast to the low deep‐blue PL with a quantum yield of only 1.7% of the as‐synthesized pristine Cs2NaBiCl6 NCs, the PL of the Cs2NaBiCl6 NCs can be impressively regulated and enhanced via doping Ag+, Mn2+, or Eu3+ ions in the double perovskite lattices. The femtosecond time‐resolved transient absorption spectroscopy is adopted to unravel the PL enhancement mechanism of the ion doping in the Cs2NaBiCl6 NCs. For the Ag+‐doping, the excitonic absorption energy of the Cs2NaBiCl6 NCs can be tuned from 3.82 to 3.48 eV with the significant improvement of the PL quantum yield (PLQY) from 1.7% to 20%. The Mn2+‐doped Cs2NaBiCl6 NCs show broad orange–red emission peak centered at 585 nm with a PLQY of 3%, owing to the 4T1→6A1 transition of octahedrally coordinated Mn2+. Eu3+‐doped Cs2NaBiCl6 NCs are endowed with strong Eu3+5D0→7FJ (J = 1, 2) orange–red emission at 591 and 615 nm. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results