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Your search keyword '"Xu, Zuo-feng"' showing total 165 results
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165 results on '"Xu, Zuo-feng"'

26. Percutaneous ultrasound-guided cholangiography using microbubbles to evaluate the dilated biliary tract: initial experience

Author

Xu Huixiong, Lu Ming-de, Xu Zuo-feng, Liu Guang-jian, Zhou Luyao, and Xie Xiaoyan

Subjects
Adult, Male, medicine.medical_specialty, Percutaneous, endocrine system diseases, Biliary Tract Diseases, medicine.medical_treatment, Percutaneous transhepatic cholangiography, Cholangiography, Image Processing, Computer-Assisted, medicine, Humans, Radiology, Nuclear Medicine and imaging, Biliary Tract, Aged, Ultrasonography, Microbubbles, Models, Statistical, medicine.diagnostic_test, Bile duct, business.industry, Reproducibility of Results, Interventional radiology, General Medicine, Middle Aged, Jaundice, Jaundice, Obstructive, medicine.anatomical_structure, Biliary tract, Feasibility Studies, Female, Radiology, medicine.symptom, Bile Duct Diseases, business, Dilatation, Pathologic
Abstract

To evaluate the feasibility of percutaneous ultrasound cholangiography (PUSC) with a microbubble contrast agent in assessing obstructive bile duct diseases. PUSC and percutaneous transhepatic cholangiography (PTC) were performed in 58 patients with obstructive jaundice undergoing ultrasound-guided percutaneous transhepatic cholangial drainage (PTCD). The PUSC findings were compared with PTC using the Chi-squared test The accuracy of PUSC in determining the level of hilar obstruction and extrahepatic obstruction was 100% (26/26) and 93.3% (30/32), while the accuracy of PTC was 100% for both (P = 1.000, P = 0.492, respectively). The accuracy of PUSC in determining the cause of hilar obstruction and extrahepatic obstruction was 92.3% (24/26) and 93.8% (30/32), respectively, while the accuracy of PTC was 84.6% (22/26) (P = 0.675) and 75% (24/34) (P = 0.039), respectively. PUSC is comparable to PTC in depicting the anatomy of the dilated bile duct tree and determining the level of obstruction for patients with obstructive jaundice, hence it expands the capacity of ultrasound in evaluating obstructive bile duct disease and simplifies the procedure of assessing obstructive jaundice. Key Points • Percutaneous ultrasound-guided cholangiography with microbubbles offers a new form of cholangiography • PUSC compares well with PTC in evaluating the dilated biliary tract. • Radiation is avoided and overall costs may be lower.

Published
2011

32. Percutaneous ultrasound-guided radiofrequency ablation treatment and genetic testing for renal cell carcinoma with Von Hippel-Lindau disease

Author

Gao, Yong, primary, Xu, Ming, additional, Xu, Zuo-Feng, additional, Liu, Da-Wei, additional, Tu, Xiang-An, additional, Zheng, Yan-Ling, additional, Wang, Dao-Hu, additional, Sun, Xiang-Zhou, additional, Zheng, Fu-Fu, additional, Qiu, Shao-Peng, additional, Lü, Ming-De, additional, Zhang, Yuan-Yuan, additional, Xie, Xiao-Yan, additional, and Deng, Chun-Hua, additional

Published
2012
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42. Unusual Benign Focal Liver Lesions

Author

Xu, Hui-Xiong, primary, Xie, Xiao-Yan, additional, Lu, Ming-De, additional, Liu, Guang-Jian, additional, Xu, Zuo-Feng, additional, Liang, Jin-Yu, additional, and Chen, Li-Da, additional

Published
2008
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49. Development and evaluation of lipid microbubbles targeted to alpha(v)beta(3)-integrin via biotin-avidin bridge.

Author

Wang, Wei, Liu, Guang-Jian, Xie, Xiao-Yan, Xu, Zuo-Feng, Chen, Li-Da, Huang, Guang-Liang, Zhou, Lu-Yao, and Lu, Ming-De

Subjects
MICROBUBBLES, QUALITY control, BIOTIN, AVIDIN, SULFUR hexafluoride
Abstract

This work was to report preparation and quality control of targeted microbubbles (MBt) via biotin-avidin bridge, specifically verification of the 'biotin-avidin-biotin' sandwich structure. (1) Lipid microbubbles filled with sulphur hexafluoride were produced by sonication and compared with commercially available microbubbles. (2) MBt were produced via biotin-avidin bridge. Specifically, the 'biotin-avidin-biotin' sandwich structure on the surface of MBt was verified in vitro using fluorescence. (3) Adhesion of alpha(v)beta(3)-integrin targeted MBt (MBααvββ3) to human umbilical vein endothelial cells (HUVECs) was tested using the parallel plate flow chamber (PPFC). 'Biotin-avidin' is a reliable method to attach molecular probe onto the surface of microbubbles. [ABSTRACT FROM AUTHOR]

Published
2012
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50. Contrast-enhanced sonography in the diagnosis of small hepatocellular carcinoma < or =2 cm.

Author

Xu, Hui-Xiong, Xie, Xiao-Yan, Lu, Ming-De, Liu, Guang-Jian, Xu, Zuo-Feng, Zheng, Yan-Lin, Liang, Jin-Yu, and Chen, Li-Da

Abstract

Purpose: To evaluate the usefulness of contrast-enhanced sonography (CEUS) in the diagnosis of small hepatocellular carcinoma (HCC) measuring < or =2 cm in diameter. Methods: We identified 104 focal liver lesions measuring < or =2 cm in 104 consecutive patients who were enrolled for baseline sonography (BUS) and CEUS examination (49 HCCs, 55 non-HCCs). A real-time, contrast-specific mode of contrast pulse sequencing and a sulphur hexafluoride-filled microbubble contrast agent were used for CEUS. The diagnostic performances of BUS and CEUS in differentiating focal liver lesions (HCC or non-HCC) were analyzed and compared. Results: On CEUS, 43 (87.8%) of the 49 HCC lesions were hyperenhanced, 5 (10.2%) were isoenhanced, and 1 (2%) was hypoenhanced during the arterial phase when compared with adjacent liver tissue. Thirty-nine (79.6%) HCCs exhibited washout from the portal phase to the late phase. The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy before and after contrast agent administration were 28.6% (14/49) versus 79.6% (39/49) (p < 0.001), 94.5% (52/55) versus 92.7% (51/55) (p > 0.05), 82.4% (14/17) versus 90.7% (39/43) (p > 0.05), 59.8% (52/87) versus 90.7% (39/43) (p < 0.01), and 63.5% (66/104) versus 86.5% (90/104) (p < 0.001), respectively. No significant difference in diagnostic performance of CEUS was found between lesions measuring < or =1.5 cm and those 1.6-2 cm and between lesions located at a depth of < or =6 cm from the skin and those located deeper. Conclusions: CEUS significantly improved the diagnostic performance in characterization of small HCCs < or =2 cm compared with BUS. [ABSTRACT FROM AUTHOR]

Published
2008
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