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Your search keyword '"Xue, Ji-Jun"' showing total 38 results
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38 results on '"Xue, Ji-Jun"'

11. Novel Bis-pyrazoline Fluorescent Probe for Cu2+ and Fe3+ Detection and Application in Cell Imaging.

Author

Yang, Yun-Shang, Wang, Fu-Nian, Zhang, Ying-Peng, Yang, Feng, and Xue, Ji-Jun

Subjects
FLUORESCENT probes, CELL imaging, CYTOTOXINS, CHEMORECEPTORS, DETECTION limit, OPTICAL properties, LIGANDS (Chemistry)
Abstract

A fluorescent probe Y((1,1'-([1,1'-biphenyl]-4,4'-diylbis(3-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazole-5,1-diyl)) bis(ethan-1-one))) was designed and synthesized, which could be used to Cu2+ and Fe3+ sensors. Through the study of optical properties, the probe Y shows good selectivity and sensitivity to Cu2+ and Fe3+ in aqueous tetrahydrofuran solution [10.0 mM HEPES, pH 7.4, THF-H2O = 9:1(v/v)] with has excellent anti-interference performance, and its detection limits were 0.931 uΜ for Cu2+ and 0.401uΜ for Fe3+. The coordination mechanism of probe Y with Cu2+ and Fe3+ was speculated and verified at DFT level and HRNM. By Hela cytotoxicity and imaging tests, probe Y not only has good biocompatibility, but also can be used for sensing Cu2+ in cells. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Lewis Acid-Mediated Efficient Synthesis of 4H-1,3-benzo-xazines and Their Derivatives 4,5-dihydro-1,3-benzo-xazepines

Author

Guo Guoying, Liu Jikun, An Junkai, Zhu Weiwei, Shi Ying, Jiang Xianxing, Zhang Hongrui, and Xue Ji-jun

Subjects
010405 organic chemistry, Chemistry, Organic Chemistry, Lewis acids and bases, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, 0104 chemical sciences
Abstract

Compounds containing 4H-1,3-benzo-xazine core usually possess characteristic features and have been applied in the fields of organic synthesis, pharmaceutical research, materials science and bioscience. Here we reported convenient and direct access to 4H-1,3- benzo-xazines and their derivatives through intramolecular cyclization of olefinic amides or ureas with good to excellent yields in the presence of TMSOTf. The properties (mild conditions, metal or additives-free, wide substrate scope and functional group tolerance) of the process made it a promising strategy to synthesize various benzo-xazines and their derivatives.

Published
2020

20. A novel pyrazoline-based fluorescence probe armed by pyrene and naphthol system for the selective detection of Cu2+and its biological application

Author

Yang, Yun-Shang, Cao, Jing-Qi, Ma, Chun-Mei, Zhang, Ying-Peng, Guo, Hui-Chen, and Xue, Ji-Jun

Abstract

A photo-induced electron transfer cationic fluorescence probe L1based on pyrene-naphthol system was designed to detect the change of Cu2+with fluorescence. The probe L1was found to selectively recognize Cu2+in aqueous ethanol solution [10.0 mmol/L HEPES, pH 7.4, EtOH–H2O = 1:1 (v/v)] without interference from other coexisting metal ions. The response of the sensor to Cu2+is transient and reversible, and anions generally have no impact on the selectivity of Cu2+. Probe L1forms complex with Cu2+in 1:1 ratio as supported by Job’s plot analysis. The binding constants of Cu2+was calculated to be 6.322 × 104L/mol using a nonlinear curve-fitting method. The detection limit of Cu2+was determined to be 1.620 × 10–7mol/L. The energy gap between HOMO and LUMO in L1and L1–Cu2+was calculated by density functional theory as 3.76 eV and 2.71 eV, respectively. In addition, the probe L1has extremely low cytotoxicity and can be used for living cell imaging studies.

Published
2022
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38. A novel chromene acyl hydrazone Schiff base organogel with colorimetric Cu2+ responsive.

Author

Yang, Yun-Shang, Wang, Li-Bin, Liang, Chuan, Wang, Fu-Nian, Zhang, Ying-peng, and Xue, Ji-Jun

Subjects
*SCHIFF bases, *MATERIALS science, *FLUORESCENCE spectroscopy, *X-ray diffraction, *DETECTION limit
Abstract

A novel ionic responsive Schiff base organic gelator was successfully designed and synthesized. The solvent selection experiment showed that the gelator showed good thermoreversible gelator behavior in aniline, valerate alcohol and isopropyl alcohol. FT-IR studies have shown that C=O and N–H of molecules participate in the formation of intermolecular hydrogen bonds, thus promoting the formation of gelator states. The XRD and SEM results show that the molecules self-assemble in the dry gelator to form the entangled network structure. In addition, the fluorescence spectrum test of gelling agent G showed that gelling agent G could specifically recognize Cu2+. Gelator G has good selectivity, low detection limit (2.92 × 10–8 M) and high sensitivity, which can be applied to the detection of Cu2+ in biology, environment and other fields. The results show that gelator G has broad application prospects in materials science, chemistry, biomedicine and other fields. It also confirms that benzopyran-derived hydrazone Schiff base compounds have far-reaching research significance. [ABSTRACT FROM AUTHOR]

Published
2024
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