Author: "Xuekang Zhang" - Searchworks@Jio Institute Digital Library Search Results

33 results on '"Xuekang Zhang"'

1. Optimal mean-variance investment and reinsurance strategies with a general Lévy process risk model

Author: Haoran Yi, Yuanchuang Shan, Huisheng Shu, and Xuekang Zhang
Subjects: Optimal investment and reinsurance, Lévy process, mean-variance criterion, Control engineering systems. Automatic machinery (General), TJ212-225, Systems engineering, TA168
Abstract: This paper is concerned with the optimal time-consistent investment and reinsurance strategies for mean-variance insurers with a general Lévy Process model. Expressly, the insurers are allowed to purchase proportional reinsurance and invest in a financial market, where the surplus of the insurers is assumed to follow a Cramér–Lundberg model and the financial market consists of one risk-free asset and one risky asset whose price process is driven by a general Lévy process. Through the verification theorem, the closed-form expressions of the optimal strategies under the mean-variance criterion are derived by a complex partial integral differential Hamilton–Jacobi–Bellman equations. Finally, numerical simulations are provided to verify the effectiveness of the proposed optimal strategies and some economic interpretations are drawn.
Published: 2024
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2. Dynamical analysis of a heterogeneous spatial diffusion Zika model with vector-bias and environmental transmission

Author: Liping Wang, Xinyu Wang, Dajun Liu, Xuekang Zhang, and Peng Wu
Subjects: zika, reaction-diffusion, vector-bias, environmental transmission, spatial heterogeneity, reproduction number, threshold dynamics, Mathematics, QA1-939, Applied mathematics. Quantitative methods, T57-57.97
Abstract: In this study, we formulate a reaction-diffusion Zika model which incorporates vector-bias, environmental transmission and spatial heterogeneity. The main question of this paper is the analysis of the threshold dynamics. For this purpose, we establish the mosquito reproduction number $ R_{1} $ and basic reproduction number $ R_{0} $. Then, we analyze the dynamical behaviors in terms of $ R_{1} $ and $ R_{0} $. Numerically, we find that the ignorance of the vector-bias effect will underestimate the infection risk of the Zika disease, ignorance of the spatial heterogeneity effect will overestimate the infection risk, and the environmental transmission is indispensable.
Published: 2024
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3. E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis

Author: Yingjie Huang, Tao Chen, Ming Jiang, Chenlu Xiong, Chao Mei, Jinping Nie, Qi Zhang, Qing Zhu, Xuan Huang, Xuekang Zhang, and Yong Li
Subjects: Cytology, QH573-671
Abstract: Abstract Intestinal ischemia-reperfusion (II/R) injury is an urgent clinical disease with high incidence and mortality, and impaired intestinal barrier function caused by excessive apoptosis of intestinal cells is an important cause of its serious consequences. Tripartite motif-containing protein 65 (TRIM65) is an E3 ubiquitin ligase that is recently reported to suppress the inflammatory response and apoptosis. However, the biological function and regulation of TRIM65 in II/R injury are totally unknown. We found that TRIM65 was significantly decreased in hypoxia-reoxygenation (H/R) induced intestinal epithelial cells and II/R-induced intestine tissue. TRIM65 knockout mice markedly aggravated intestinal apoptosis and II/R injury. To explore the molecular mechanism of TRIM65 in exacerbating II/R-induced intestinal apoptosis and damage, thymocyte selection-associated high mobility group box factor 4 (TOX4) was screened out as a novel substrate of TRIM65 using the yeast two-hybrid system. TRIM65 binds directly to the N-terminal of TOX4 through its coiled-coil and SPRY structural domains. Immunofluorescence confocal microscopy showed that they can co-localize both in the cytoplasm and nucleus. Furthermore, TRIM65 mediated the K48 ubiquitination and degradation of TOX4 depending on its E3 ubiquitin ligase activity. In addition, TRIM65 inhibits H/R-induced intestinal epithelial apoptosis via TOX4. In summary, our results indicated that TRIM65 promotes ubiquitination and degradation of TOX4 to inhibit apoptosis in II/R. These findings provide a promising target for the clinical treatment of II/R injury.
Published: 2024
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4. Research on fault diagnosis of time-domain vibration signal based on convolutional neural networks

Author: Mingyong Li, Qingmin Wei, Hongya Wang, and Xuekang Zhang
Subjects: Convolutional neural network, time-domain vibration signal, fault diagnosis, machine learning, Control engineering systems. Automatic machinery (General), TJ212-225, Systems engineering, TA168
Abstract: In order to maintain the safe operation of various types of equipment, the health status of main components should be monitored in real-time, and the demand for intelligent fault diagnosis algorithm has increased sharply. However, the traditional intelligent diagnosis algorithm is based on the manual method for signal feature extraction, which has high requirements for expert experience and poor generality. A convolutional neural network, with big data as its engine, is the most effective pattern classification algorithm at present. In this paper, the convolutional neural network is applied to time-domain vibration signal fault diagnosis, taking the bearing as an example, and an intelligent diagnosis method of bearing based on convolution neural network is proposed. The proposed method does not need manual feature extraction, and can automatically complete feature extraction and automatic fault recognition. The convolutional neural network has three convolutional layers. We use data enhancement techniques for the input raw signal and convert the one-dimensional original time-domain vibration signal into a two-dimensional signal. The model shows good results on CWRU dataset and the recognition accuracy of the algorithm in the CWRU bearing database is more than 96%.
Published: 2019
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5. The Emerging Roles of Tripartite Motif Proteins (TRIMs) in Acute Lung Injury

Author: Yingjie Huang, Yue Xiao, Xuekang Zhang, Xuan Huang, and Yong Li
Subjects: Immunologic diseases. Allergy, RC581-607
Abstract: Acute lung injury (ALI) is an inflammatory disorder of the lung that causes high mortality and lacks any pharmacological intervention. Ubiquitination plays a critical role in the pathogenesis of ALI as it regulates the alveolocapillary barrier and the inflammatory response. Tripartite motif (TRIM) proteins are one of the subfamilies of the RING-type E3 ubiquitin ligases, which contains more than 80 distinct members in humans involved in a broad range of biological processes including antivirus innate immunity, development, and tumorigenesis. Recently, some studies have shown that several members of TRIM family proteins play important regulatory roles in inflammation and ALI. Herein, we integrate emerging evidence regarding the roles of TRIMs in ALI. Articles were selected from the searches of PubMed database that had the terms “acute lung injury,” “ubiquitin ligases,” “tripartite motif protein,” “inflammation,” and “ubiquitination” using both MeSH terms and keywords. Better understanding of these mechanisms may ultimately lead to novel therapeutic approaches by targeting TRIMs for ALI treatment.
Published: 2021
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6. The valuation of options on discrete dividend-paying stocks

Author: Yuanchuang Shan, Huisheng Shu, Xuekang Zhang, and Haoran Yi
Subjects: Economics and Econometrics
Published: 2023

7. Stability of stochastic Gilpin-Ayala model driven by α-stable process under regime switching

Author: Xuekang Zhang, Huisheng Shu, and Dajun Liu
Subjects: Statistics and Probability
Published: 2022

8. Effects of remimazolam on cerebral oxygen saturation and postoperative cognitive function in elderly undergoing nasal endoscopic surgery: a retrospective exploratory study

Author: yingjie Huang, qian Hu, qiuhong Chen, qinqin Chen, bowen Liu, wenming Yang, and xuekang Zhang
Abstract: Background Remimazolam is a new type of benzodiazepine, which has been widely used for general anesthesia and sedation. However, the association between remimazolam and intraoperative cerebral oxygen saturation and postoperative cognitive function in older patients undergoing nasal endoscopic surgery remains unclear. This study aimed to evaluate the effects of general anesthesia with remimazolam during nasal endoscopic surgery on intraoperative cerebral oxygen saturation and postoperative cognitive function in the elderly.Methods This single-center retrospective study reviewed data from patients older than 65 years who underwent nasal endoscopic surgery under general anesthesia at our institution between December 2020 and December 2021. Patient intraoperative regional cerebral oxygen saturation (rcSO2) and Montreal Cognitive Assessment (MoCA) scores were obtained from patient records. According to the sedatives used in anesthesia, the patients were divided into the remimazolam (R) and propofol groups (P) for analysis.Results Sixty patients were included in the final analysis (R group, n = 30; P group, n = 30). The relative maximum reduction of intraoperative rcSO2 was significantly lower in the R group than in the P group (P Conclusion Remimazolam may benefit elderly patients during nasal endoscopic surgery in terms of rcSO2, but has no significant association with postoperative cognitive function.
Published: 2023

9. Asymptotic behavior of maximum likelihood estimators for Ornstein–Uhlenbeck process with large linear drift

Author: Xuekang Zhang
Subjects: Modeling and Simulation
Abstract: In this paper, we study the asymptotic behavior of maximum likelihood estimators for Ornstein–Uhlenbeck process with large linear drift [Formula: see text], [Formula: see text], where [Formula: see text], and [Formula: see text] is a given standard Brownian motion. The law of iterated logarithm, consistency and asymptotic distributions of the estimators are discussed based on the continuous observation [Formula: see text] as [Formula: see text].
Published: 2023

10. Parameter Estimation for Ornstein–Uhlenbeck Driven by Ornstein–Uhlenbeck Processes with Small Lévy Noises

Author: Xuekang Zhang, Huisheng Shu, and Haoran Yi
Subjects: Statistics and Probability, General Mathematics, Statistics, Probability and Uncertainty
Published: 2022

11. Optimal portfolio and reinsurance with two differential risky assets

Author: Haoran Yi, Xuekang Zhang, Yuanchuang Shan, and Huisheng Shu
Subjects: Statistics and Probability
Published: 2022

12. Nonparametric estimation of periodic signal disturbed by α-stable noises

Author: Xuekang Zhang, Haoran Yi, and Huisheng Shu
Subjects: Statistics and Probability, Statistics, Probability and Uncertainty
Published: 2022

13. The Emerging Roles of Tripartite Motif Proteins (TRIMs) in Acute Lung Injury

Author: Xuekang Zhang, Yue Xiao, Xuan Huang, Yingjie Huang, and Yong Li
Subjects: Ubiquitin-Protein Ligases, Acute Lung Injury, Immunology, Anti-Inflammatory Agents, Inflammation, Review Article, Computational biology, Lung injury, medicine.disease_cause, Tripartite Motif Proteins, Pathogenesis, Ubiquitin, medicine, Humans, Immunology and Allergy, Lung, Innate immune system, biology, Ubiquitination, General Medicine, RC581-607, respiratory system, respiratory tract diseases, biology.protein, Immunologic diseases. Allergy, medicine.symptom, RING Finger Domains, Carcinogenesis, TRIM Family
Abstract: Acute lung injury (ALI) is an inflammatory disorder of the lung that causes high mortality and lacks any pharmacological intervention. Ubiquitination plays a critical role in the pathogenesis of ALI as it regulates the alveolocapillary barrier and the inflammatory response. Tripartite motif (TRIM) proteins are one of the subfamilies of the RING-type E3 ubiquitin ligases, which contains more than 80 distinct members in humans involved in a broad range of biological processes including antivirus innate immunity, development, and tumorigenesis. Recently, some studies have shown that several members of TRIM family proteins play important regulatory roles in inflammation and ALI. Herein, we integrate emerging evidence regarding the roles of TRIMs in ALI. Articles were selected from the searches of PubMed database that had the terms “acute lung injury,” “ubiquitin ligases,” “tripartite motif protein,” “inflammation,” and “ubiquitination” using both MeSH terms and keywords. Better understanding of these mechanisms may ultimately lead to novel therapeutic approaches by targeting TRIMs for ALI treatment.
Published: 2021

14. Trajectory fitting estimation for a class of SDEs with small Lévy noises

Author: Xuekang Zhang and Huisheng Shu
Subjects: Statistics and Probability
Published: 2022

15. Parameter estimation for integrated Ornstein–Uhlenbeck processes with small Lévy noises

Author: Huisheng Shu, Ziwei Jiang, and Xuekang Zhang
Subjects: Statistics and Probability, Statistics, Probability and Uncertainty
Published: 2023

16. Perioperative Pain Management With Bilateral Pecto-intercostal Fascial Block in Pediatric Patients Undergoing Open Cardiac Surgery

Author: Yang Zhang, Xuekang Zhang, and Shibiao Chen
Subjects: Cardiology and Cardiovascular Medicine
Abstract: PurposesPediatric open cardiac surgical patients usually suffer from acute pain after operation. The current work aimed to explore the impact of bilateral PIFB in children suffering from open cardiac surgery.MethodsThis work randomized altogether 110 child patients as bilateral PIFB (PIF) and non-nerve block (SAL) groups. This work adopted post-operative pain at exercise and rest statuses as the primary endpoint, whereas time-to-drain removal/extubation/initial defecation, intraoperative/post-operative fentanyl use, and length of ICU and hospital stay as the secondary endpoints.ResultsMOPS were significantly higher at 24-h post-operatively at coughing and rest statuses in SAL group compared with PIF group. Meanwhile, PIF group exhibited markedly lower intraoperative/post-operative fentanyl use amounts, as well as markedly reduced time-to-extubation/initial flatus, and length of ICU/hospital stay.ConclusionBilateral PIFB in pediatric open cardiac surgical patients provide effective analgesia and lower the length of hospital stay.
Published: 2022
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17. Option pricing under a Markov-modulated Merton jump-diffusion dividend

Author: Haoran Yi, Huisheng Shu, Xuekang Zhang, and Yuanchuang Shan
Subjects: Statistics and Probability, 021103 operations research, Markov chain, Jump diffusion, 0211 other engineering and technologies, 02 engineering and technology, 01 natural sciences, Risk-neutral measure, Esscher transform, Valuation (logic), 010104 statistics & probability, Valuation of options, Dividend, 0101 mathematics, Mathematical economics, Mathematics
Abstract: In this paper, the valuation of European option is investigated when the discrete dividends are described by Markov-modulated Merton jump-diffusion process. According to the dividend discount theor...
Published: 2021

18. Parameter estimation for generalized Ait-Sahalia-type interest rate model

Author: Huisheng Shu and Xuekang Zhang
Subjects: Statistics and Probability, 021103 operations research, Discrete observation, Estimation theory, 0211 other engineering and technologies, Estimator, 02 engineering and technology, Type (model theory), 01 natural sciences, Quadratic variation, 010104 statistics & probability, Short-rate model, Modeling and Simulation, Statistics, Applied mathematics, Ergodic theory, 0101 mathematics, Mathematics
Abstract: This paper is concerned with the parameter estimation problem for generalized Ait-Sahalia-type interest rate model based on discrete observation. The parameter estimators are obtained by applying t...
Published: 2021

19. Dexmedetomidine reduces enteric glial cell injury induced by intestinal ischaemia-reperfusion injury through mitochondrial localization of TERT

Author: Qian Hu, Xiao‐Ming Liu, Zheng‐Ren Liu, Zhi‐Yi Liu, Huai‐Gen Zhang, Qin Zhang, Yuan‐Lu Huang, Qiu‐Hong Chen, Wen‐Xiang Wang, and XueKang Zhang
Subjects: Mitochondrial Permeability Transition Pore, Reperfusion Injury, Molecular Medicine, Animals, Cell Biology, Rats, Wistar, DNA, Mitochondrial, Neuroglia, Telomerase, Dexmedetomidine, Matrix Metalloproteinases, Rats
Abstract: This study was performed to uncover the effects of dexmedetomidine on oxidative stress injury induced by mitochondrial localization of telomerase reverse transcriptase (TERT) in enteric glial cells (EGCs) following intestinal ischaemia-reperfusion injury (IRI) in rat models. Following establishment of intestinal IRI models by superior mesenteric artery occlusion in Wistar rats, the expression and distribution patterns of TERT were detected. The IRI rats were subsequently treated with low or high doses of dexmedetomidine, followed by detection of ROS, MDA and GSH levels. Calcein cobalt and rhodamine 123 staining were also carried out to detect mitochondrial permeability transition pore (MPTP) and the mitochondrial membrane potential (MMP), respectively. Moreover, oxidative injury of mtDNA was determined, in addition to analyses of EGC viability and apoptosis. Intestinal tissues and mitochondria of EGCs were badly damaged in the intestinal IRI group. In addition, there was a reduction in mitochondrial localization of TERT, oxidative stress, whilst apoptosis of EGCs was increased and proliferation was decreased. On the other hand, administration of dexmedetomidine was associated with promotion of mitochondrial localization of TERT, whilst oxidative stress, MPTP and mtDNA in EGCs, and EGC apoptosis were all inhibited, and the MMP and EGC viability were both increased. A positive correlation was observed between different doses of dexmedetomidine and protective effects. Collectively, our findings highlighted the antioxidative effects of dexmedetomidine on EGCs following intestinal IRI, as dexmedetomidine alleviated mitochondrial damage by enhancing the mitochondrial localization of TERT.
Published: 2022

20. Nonparametric estimation of the trend for stochastic differential equations driven by small α-stable noises

Author: Haoran Yi, Huisheng Shu, and Xuekang Zhang
Subjects: Statistics and Probability, Estimation, 010102 general mathematics, Nonparametric statistics, Asymptotic distribution, Estimator, 01 natural sciences, Stable distribution, 010104 statistics & probability, Stochastic differential equation, Rate of convergence, Consistency (statistics), Applied mathematics, 0101 mathematics, Statistics, Probability and Uncertainty, Mathematics
Abstract: The present paper deals with the problem of nonparametric estimation of the trend for stochastic differential equations driven by small α -stable noises based on continuous-time observation. Under some certain conditions, we derive the uniform consistency and the rate of convergence of the nonparametric estimator. Besides, the asymptotic distribution of the estimator in our setting is shown to be a stable distribution.
Published: 2019

21. Parameter estimation for certain nonstationary processes driven by α-stable motions

Author: Haoran Yi, Xuekang Zhang, and Huisheng Shu
Subjects: Statistics and Probability, Estimation theory, Consistency (statistics), Parametric estimation, Trajectory, Applied mathematics, Stable distribution, Mathematics
Abstract: The present article deals with the problem of parametric estimation for certain nonstationary processes driven by α-stable motions. The trajectory fitting method combined with the weighted least sq...
Published: 2019

22. Stabilization and destabilization of nonlinear stochastic differential delay equations

Author: Xuekang Zhang, Haoran Yi, and Huisheng Shu
Subjects: Statistics and Probability, Nonlinear system, Modeling and Simulation, Mathematics::Optimization and Control, Key (cryptography), Applied mathematics, Differential (mathematics), Mathematics
Abstract: This present paper deals with the problem of stabilization and destabilization of nonlinear stochastic differential delay equations. The key techniques used in this paper are the LaSalle-ty...
Published: 2019

23. Option pricing under a Markov-modulated jump-diffusion dividend

Author: Yuanchuang Shan, Haoran Yi, Xuekang Zhang, and HuiSheng Shu
Subjects: Esscher transform, Markov chain, Dividend discount model, Valuation of options, Jump diffusion, Economics, Econometrics, Dividend, Measure (mathematics), Probability measure
Abstract: This paper investigates the European option valuation under the condition that the dividend payments follow a Markov-modulated Merton jump-diffusion model. We consider the dividend discount model under real probability measure, the stock price process is then deduced. The regime switching Esscher transform is employed to determine a risk-neutral measure. Finally, we obtain the closed form solution of European option when the dividend announcement time and the dividend payment time are consistent or inconsistent.
Published: 2020

24. MiR-520b promotes the progression of non-small cell lung cancer through activating Hedgehog pathway

Author: Xin Gan, Xiaoming Liu, Yuben Tong, Xuekang Zhang, and Jichun Liu
Subjects: 0301 basic medicine, Lung Neoplasms, Nerve Tissue Proteins, Zinc Finger Protein Gli2, SPOP, NSCLC, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Zinc Finger Protein Gli3, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, GLI2, medicine, Humans, Hedgehog Proteins, Hh pathway, Lung cancer, 3' Untranslated Regions, neoplasms, Hedgehog, Cell Proliferation, Hyperactivation, business.industry, miR‐520b, Ubiquitination, Nuclear Proteins, Original Articles, Cell Biology, medicine.disease, Hedgehog signaling pathway, respiratory tract diseases, Gene Expression Regulation, Neoplastic, Repressor Proteins, MicroRNAs, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Original Article, Non small cell, business
Abstract: Although the non‐small cell lung cancer (NSCLC) is one of the most malignant tumours worldwide, the mechanisms controlling NSCLC tumourigenesis remain unclear. Here, we find that the expression of miR‐520b is up‐regulated in NSCLC samples. Further studies have revealed that miR‐520b promotes the proliferation and metastasis of NSCLC cells. In addition, miR‐520b activates Hedgehog (Hh) pathway. Inhibitor of Hh pathway could relieve the oncogenic effect of miR‐520b upon NSCLC cells. Mechanistically, we demonstrate that miR‐520b directly targets SPOP 3′‐UTR and decreases SPOP expression, culminating in GLI2/3 stabilization and Hh pathway hyperactivation. Collectively, our findings unveil that miR‐520b promotes NSCLC tumourigenesis through SPOP‐GLI2/3 axis and provide miR‐520b as a potential diagnostic biomarker and therapeutic target for NSCLC.
Published: 2018

25. Exponential ergodicity for population dynamics driven byα-stable processes

Author: Xuekang Zhang, Jinying Tong, and Zhenzhong Zhang
Subjects: Statistics and Probability, education.field_of_study, Stationary distribution, Semigroup, 010102 general mathematics, Mathematical analysis, Population, 01 natural sciences, Noise (electronics), Exponential function, 010104 statistics & probability, Total variation, Convergence (routing), Jump, Statistical physics, 0101 mathematics, Statistics, Probability and Uncertainty, education, Mathematics
Abstract: In this paper, we consider the stochastic Lotka–Volterra model driven by spectrally positive stable processes. We show that if the coefficients of the noise are small, then this kind of pure jump stochastic dynamic has a unique stationary distribution. Besides, we prove that the rate of the transition semigroup convergence to the stationary distribution in the total variation distance is exponential. However, if the noise is sufficiently large, then this stochastic dynamic will become extinct with probability one. Computer simulations are presented to illustrate our theory. To the best of our knowledge, it is the first result to give the exponential ergodicity for population dynamics driven by spectrally positive α -stable processes.
Published: 2017

26. The a2AR/Caveolin-1/p38MAPK/NF-κB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia-reperfusion.

Author: Lin Xu, Taiyuan Li, Qiuhong Chen, Zhen Liu, Yuesheng Chen, Kai Hu, and Xuekang Zhang
Subjects: LUNG injuries, INTESTINAL injuries, DEXMEDETOMIDINE, INTESTINES, SPECIFIC gravity
Abstract: Intestinal ischaemia-reperfusion (I/R) injury can result in acute lung injury due to ischaemia and hypoxia. Dexmedetomidine (Dex), a highly selective alpha2-noradrenergic receptor (a2AR) agonist used in anaesthesia, is reported to regulate inflammation in organs. This study aimed to investigate the role and mechanism of Dex in lung injury caused by intestinal I/R. After establishing a rat model of intestinal I/R, we measured the wet-to-dry specific gravity of rat lungs upon treatments with Dex, SB239063 and the a2AR antagonist Atipamezole. Moreover, injury scoring and histopathological studies of lung tissues were performed, followed by ELISA detection on tumour necrosis factor-a (TNF-a), interleukin (IL)-1ß and IL-6 expression. Correlation of Caveolin-1 (Cav-1) protein expression with p38, p-p38, p-p65 and p65 in rat lung tissues was analysed, and the degree of cell apoptosis in lung tissues after intestinal I/R injury was detected by TUNEL assay. The lung injury induced by intestinal I/R was a dynamic process. Moreover, Dex had protective effects against lung injury by mediating the expression of Cal-1 and a2A-AR. Specifically, Dex promoted Cav-1 expression via a2A-AR activation and mitigated intestinal I/R-induced lung injury, even in the presence of Atipamezole. The protective effect of Dex on intestinal I/R-induced lung injury was also closely related to a2A-AR/p38 mitogen-activated protein kinases/nuclear factor-kappaB (MAPK/NF-κB) pathway. Dex can alleviate pulmonary inflammation after in intestinal I/R by promoting Cav-1 to inhibit the activation of p38 and NF-κB. In conclusion, Dex can reduce pulmonary inflammatory response even after receiving threats from both intestinal I/R injury and Atipamezole. [ABSTRACT FROM AUTHOR]
Published: 2021
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27. Parameter estimation for non-stationary reflected Ornstein–Uhlenbeck processes driven by α-stable noises

Author: Huisheng Shu, Haoran Yi, and Xuekang Zhang
Subjects: Statistics and Probability, Estimation theory, 010102 general mathematics, Estimator, Ornstein–Uhlenbeck process, 01 natural sciences, Stable distribution, 010104 statistics & probability, Exponential stability, Rate of convergence, Consistency (statistics), Applied mathematics, Stochastic drift, 0101 mathematics, Statistics, Probability and Uncertainty, Mathematics
Abstract: This paper is concerned with the parameter estimation problem for non-stationary reflected Ornstein–Uhlenbeck processes driven by stable noises by using the trajectory fitting method combined with the weighted least squares technique. Under some regularity conditions, we obtain the consistency and the rate of convergence of the proposed estimator of the drift rate. The asymptotic stability property of the estimator in our setting is also proved.
Published: 2020

28. The surgical safety checklist and patient outcomes after surgery

Author: T.E.F. Abbott, T. Ahmad, M.K. Phull, A.J. Fowler, R. Hewson, B.M. Biccard, M.S. Chew, M. Gillies, R.M. Pearse, Rupert M. Pearse, Scott Beattie, Pierre-Alain Clavien, Nicolas Demartines, Lee A. Fleisher, Mike Grocott, James Haddow, Andreas Hoeft, Peter Holt, Rui Moreno, Naomi Pritchard, Andrew Rhodes, Duminda Wijeysundera, Matt Wilson, Tahania Ahmed, Kirsty Everingham, Russell Hewson, Marta Januszewska, Mandeep-Kaur Phull, Richard Halliwell, Mark Shulman, Paul Myles, Werner Schmid, Michael Hiesmayr, Patrick Wouters, Stefan de Hert, Suzana Lobo, Xiangming Fang, Lars Rasmussen, Emmanuel Futier, Matthieu Biais, Aurélien Venara, Karem Slim, Michael Sander, Despoina Koulenti, Kostoula Arvaniti, Mathew Chan, Atul Kulkarni, Susilo Chandra, Aida Tantri, Emad Geddoa, Muntadhar Abbas, Giorgio Della Rocca, Datin Sivasakthi, Marzida Mansor, Pastor Luna, Arthur Bouwman, Wolfgang Buhre, Vanessa Beavis, Douglas Campbell, Tim Short, Tunde Osinaike, Ricardo Matos, Ioana Grigoras, Mikhail Kirov, Denis Protsenko, Bruce Biccard, Cesar Aldecoa, Michelle Chew, Christoph Hofer, Martin Hubner, James Ditai, Tamas Szakmany, Lee Fleisher, Marissa Ferguson, Michael MacMahon, Ritchie Cherian, Helen Currow, Kathirgamanathan Kanathiban, David Gillespie, Edward Pathmanathan, Katherine Phillips, Jenifer Reynolds, Joanne Rowley, Jeanene Douglas, Ross Kerridge, Sameer Garg, Michael Bennett, Megha Jain, David Alcock, Nico Terblanche, Rochelle Cotter, Kate Leslie, Marcelle Stewart, Nicolette Zingerle, Antony Clyde, Oliver Hambidge, Adam Rehak, Sharon Cotterell, Wilson Binh Quan Huynh, Timothy McCulloch, Erez Ben-Menachem, Thomas Egan, Jennifer Cope, Paul Fellinger, Markus Haisjackl, Simone Haselberger, Caroline Holaubek, Paul Lichtenegger, Florian Scherz, Franz Hoffer, Veronika Cakova, Andreas Eichwalder, Norbert Fischbach, Reinhold Klug, Elisabeth Schneider, Martin Vesely, Reinhart Wickenhauser, Karl Gernot Grubmueller, Marion Leitgeb, Friedrich Lang, Nancy Toro, Marlene Bauer, Friedrich Laengle, Claudia Haberl, Thomas Mayrhofer, Christoph Trybus, Christian Buerkle, Karin Forstner, Reinhard Germann, Harald Rinoesl, Elke Schindler, Ernst Trampitsch, Gerhard Bogner, Daniel Dankl, Martin Duenser, Gerhard Fritsch, Ilse Gradwohl-Matis, Andreas Hartmann, Thomas Hoelzenbein, Tarkan Jaeger, Franz Landauer, Gregor Lindl, Michael Lux, Johannes Steindl, Ottokar Stundner, Christian Szabo, Jawad Bidgoli, Hans Verdoodt, Patrice Forget, David Kahn, Fernande Lois, Mona Momeni, Caroline Prégardien, Audrey Pospiech, Arnaud Steyaert, Laurent Veevaete, Dirk De Kegel, Karen De Jongh, Luc Foubert, Carine Smitz, Marcel Vercauteren, Jan Poelaert, Veerle Van Mossevelde, Jacques Abeloos, Stefaan Bouchez, Marc Coppens, Luc De Baerdemaeker, Isabel Deblaere, Ann De Bruyne, Kristine Fonck, Bjorn Heyse, Tom Jacobs, Koen Lapage, Anneliese Moerman, Martine Neckebroek, Aliaksandra Parashchanka, Nathalie Roels, Nancy Van Den Eynde, Michael Vandenheuvel, JurgenVan Limmen, Ann Vanluchene, Caroline Vanpeteghem, Piet Wyffels, Christel Huygens, Punitha Vandenbempt, Marc Van de Velde, Dimitri Dylst, Bruno Janssen, Evelien Schreurs, Fábia Berganton Aleixo, Keulle Candido, Hugo Dias Batista, Mario Guimarães, Jaqueline Guizeline, João Hoffmann, Francisco Ricardo Marques Lobo, Vinícius Nascimento, Katia Nishiyama, Lucas Pazetto, Daniela Souza, Rodrigo Souza Rodrigues, Ana Maria Vilela dos Santos, Jaquelline Jardim, Luiz Marcelo Sá Malbouisson, Joao Silva, Paulo do Nascimento Junior, Thalissa Hermínia Baio, Gabriel Isaac Pereira de Castro, Henri Roger Watanabe Oliveira, Cristina Prata Amendola, Gutemberg Cardoso, Daniela Ortega, Ana Flavia Brotto, Mirella Cristine De Oliveira, Álvaro Réa-Neto, Fernando Dias, Maria Eduarda Travi, Luiza Zerman, Pedro Azambuja, Marcos Freitas Knibel, Antonio Martins, William Almeida, Calim Neder Neto, Maria Angela Tardelli, Eliana Caser, Marcio Machado, Crisitiano Aguzzoli, Sérgio Baldisserotto, Fernanda Beck Tabajara, Fernanda Bettega, La Hore Correa Rodrigues Júnior, Julia de Gasperi, Lais Faina, Marcos Farias Nolasco, Bruna Ferreira da Costa Fischer, Mariana Fosch de Campos Ferreira, Cristina Hartmann, Marta Kliemann, Gustavo Luis Hubert Ribeiro, Julia Merladete Fraga, Thiago Motta Netto, Laura Valduga Pozza, Paulo Rafael Wendling, Caroline Azevedo, Juliana Garcia, Marcel Lopes, Bernardo Maia, Paula Maselli, Ralph Melo, Weslley Mendes, Matheus Neves, Jacqueline Ney, Claudio Piras, Christopher Applewhaite, Adrienne Carr, Lorraine Chow, Kaylene Duttchen, Julena Foglia, Michael Greene, Ashley Hinther, Kendra Houston, Thomas Jared McCormick, Jennifer Mikhayel, Sam Montasser, Alex Ragan, Andrew Suen, Adrianna Woolsey, Hai Chuan Yu, Duane Funk, Stephen Kowalski, Regina Legaspi, Heather McDonald, Faisal Siddiqui, Jeremy Pridham, Bernadette Rowe, Sonia Sampson, Barton Thiessen, Geoff Zbitnew, Andre Bernard, Ronald George, Philip Jones, Rita Moor, Naveed Siddiqui, Alexandra Wolfer, Diem Tran, Denyse Winch, Gary Dobson, Thomas McCormick, Osama Montasser, Richard Hall, Leyla Baghirzada, Gerard Curley, Si Yuan Dai, Gregory Hare, Esther Lee, Uma Shastri, Albert Tsui, Anmol Yagnik, Danielle Alvares, Stephen Choi, Heather Dwyer, Kathrina Flores, 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Adeolu, Tinuola Adigun, Mukaila Akinwale, Oluyemi Fasina, Olalere Gbolahan, Olusola Idowu, Rotimi Peter Olonisakin, Babatunde Babasola Osinaike, Felicia Asudo, Danladi Mshelia, Lukman Abdur-Rahman, Olayide Agodirin, Jibril Bello, Benjamin Bolaji, Olanrewaju Olubukola Oyedepo, Humphrey Ezike, Ikechukwu Iloabachie, Ikemefuna Okonkwo, Elias Onuora, Tonia Onyeka, Innocent Ugwu, Friday Umeh, Olubusola Alagbe-Briggs, Amabra Dodiyi-Manuel, Richard Echem, Bright Obasuyi, Bisola Onajin-Obembe, Maria Expedito Bandeira, Alda Martins, Miguel Tomé, Ana Cristina Miranda Martins Costa, Andriy Krystopchuk, Teresa Branco, Simao Esteves, Marco António Melo, Júlia Monte, Fernando Rua, Isabel Martins, Vítor Miguel Pinho-Oliveira, Carla Maria Rodrigues, Raquel Cabral, Sofia Marques, Sara Rêgo, Joana Sofia Teixeira Jesus, Maria Conceição Marques, Cristina Romao, Sandra Dias, Ana Margarida Santos, Maria Joao Alves, Cristina Salta, Salome Cruz, Célia Duarte, António Armando Furtado Paiva, Tiago do Nascimento Cabral, Dionisio Faria e Maia, Rui Freitas Mendonça Correia da Silva, Anuschka Langner, Hernâni Oliveira Resendes, Maria da Conceição Soares, Alexandra Abrunhosa, Filomena Faria, Lina Miranda, Helena Pereira, Sofia Serra, Daniela Ionescu, Simona Margarit, Calin Mitre, Horatiu Vasian, Gratiela Manga, Andreea Stefan, Dana Tomescu, Daniela Filipescu, Marilena-Alina Paunescu, Mihai Stefan, Radu Stoica, Laura Gavril, Emilia Pătrășcanu, Irina Ristescu, Daniel Rusu, Ciresica Diaconescu, Gabriel Florin Iosep, Dorin Pulbere, Irina Ursu, Andreea Balanescu, Ioana Grintescu, Liliana Mirea, Irina Rentea, Mihaela Vartic, Mary-Nicoleta Lupu, Dorin Stanescu, Lavinea Streanga, Oana Antal, Natalia Hagau, Dumitru Patras, Cristina Petrisor, Flaviu Tosa, Sebastian Tranca, Sanda Maria Copotoiu, Liviu Lucian Ungureanu, Cristian Remus Harsan, Marius Papurica, Daniela Denisa Cernea, Nicoleta Alice Dragoescu, Laura Aflori CarmenVaida, Oana Roxana Ciobotaru, Mariana Aignatoaie, Cristina Paula Carp, Isabelle Cobzaru, Oana Mardare, Bianca Purcarin, Valentin Tutunaru, Victor Ionita, Mirela Arustei, Anisoara Codita, Mihai Busuioc, Ion Chilinciuc, Cristina Ciobanu, Ioana Belciu, Eugen Tincu, Mihaela Blaj, Ramona - Mihaela Grosu, Gigel Sandu, Dana Bruma, Dan Corneci, Madalina Dutu, Adriana Krepil, Elena Copaciu, Clementina Oana Dumitrascu, Ramona Jemna, Florentina Mihaescu, Raluca Petre, Cristina Tudor, Elena Ursache, Alexander Kulikov, Andrey Lubnin, Evgeny Grigoryev, Stanislav Pugachev, Alexander Tolmasov, Ayyaz Hussain, Yana Ilyina, Anna Roshchina, Aleksandr Iurin, Elena Chazova, Artem Dunay, Alexey Karelov, Irina Khvedelidze, Olga Voldaeva, Vladislav Belskiy, Parvin Dzhamullaev, Elena Grishkowez, Vladimir Kretov, Valeriy Levin, Aleksandr Molkov, Sergey Puzanov, Aleksandr Samoilenko, Aleksandr Tchekulaev, Valentina Tulupova, Ivan Utkin, Nikki Leigh Allorto, David Gray Bishop, Pierre Monji Builu, Carel Cairns, Ashish Dasrath, Jacques de Wet, Marielle den Hoedt, Ben Grey, Morgan Philip Hayes, Belinda Senta Küsel, Nomcebo Shangase, Robert Wise, Sharon Cacala, Zane Farina, Vishendran Govindasamy, Carl-Heinz Kruse, Carolyn Lee, Leonard Marais, Thinagrin Dhasarthun Naidoo, Chantal Rajah, Reitze Nils Rodseth, Lisa Ryan, Richard von Rhaden, Suwayba Adam, Christella Alphonsus, Yusuf Ameer, Frank Anderson, Sujith Basanth, Sudha Bechan, Chettan Bhula, Bruce M. Biccard, Thuli Biyase, Ines Buccimazza, Jorge Cardosa, James Chen, Bhavika Daya, Leanne Drummond, Ali Elabib, Ehab Helmy Abdel Goad, Ismail E. Goga, Riaz Goga, R. Harrichandparsad, Richard E. Hodgson, J. Jordaan, Nicky Kalafatis, Christian Kampik, A.T. Landers, Emil Loots, Rajhmum Madansein, Anil Madaree, Thandinkosi E. Madiba, Vukani T. Manzini, Mbali Mbuyisa, Rajan Moodley, Mduduzi Msomi, Innocent Mukama, Desigan Naidoo, Rubeshan Naidoo, Tesuven K. Naidu, Sindiswa Ntloko, Eneshia Padayachee, Lucelle Padayachee, Martijn Phaff, Bala Pillay, Desigan Pillay, Lutchmee Pillay, Anupa Ramnarain, Suren R. Ramphal, Paul Ryan, Ahmed Saloojee, Motshedisi Sebitloane, Noluyolo Sigcu, Jenna L. Taylor, Alexandra Torborg, Linda Visser, Philip Anderson, Alae Conradie, Mathew de Swardt, Martin de Villiers, Johan Eikman, Riaan Liebenberg, Johan Mouton, Abbey Paton, Louwrence van der Merwe, Candice Wilscott-Davids, Wendy Joan Barrett, Marlet Bester, Johan de Beer, Jacques Geldenhuys, Hanni Gouws, Jan-Hendrik Potgieter, Magdel Strydom, Edwin WilberforceTurton, Rubendraj R. Chetty, Subash Chirkut, Larissa Cronje, Kim de Vasconcellos, Nokukhanya Z. Dube, N. Sibusiso Gama, Garyth M. Green, Randolph Green-Thompson, Suman Mewa Kinoo, Prenolin Kistnasami, Kapil Maharaj, Manogaran S. Moodley, Sibongile J. Mothae, Ruvashni Naidoo, M. Aslam F Noorbhai, Vivesh Rughubar, Jenendhiran Reddy, Avesh Singh, David L. Skinner, Murray J. Smith, Bhagwan Singh, Ravi Misra, Maheshwar Naidoo, Pireshin Ramdharee, Yvonne Selibea, Selina Sewpersad, Shailendra Sham, Joseph D. Wessels, Cucu Africander, Tarek Bejia, Stephen P. Blakemore, Marisa Botes, Bimalshakth Bunwarie, Carlos B. Hernandez, Mohammud A. Jeeraz, Dagmara A. Legutko, Acela G. Lopez, Jenine N. De Meyer, Tanaka Muzenda, Noel Naidoo, Maryam Patel, Rao Pentela, Marina Junge, Naj Mansoor, Lana Rademan, Pawel Scislowski, Ismail Seedat, Bianca van den Berg, Doreen van der Merwe, Steyn van Wyk, Komalan Govender, Darshan Naicker, Rajesh Ramjee, Mueen Saley, Warren Paul Kuhn, Roel Matos-Puig, Zaheer Moolla Alberto Lisi, Gisela Perez, Anna Valle Beltran, Angels Lozano, Carlos Delgado Navarro, Alejandro Duca, Ernesto Pastor Martinez Ernesto, Carlos Ferrando, Isabel Fuentes, Maria Luisa García-Pérez, Estefania Gracia, Ana Izquierdo Palomares, Antonio Katime, Amanda Miñana, Raul Raul Incertis, Esther Romero, Carolina Soledad Romero Garcia, Concepcion Rubio, Tania Socorro Artiles, Marina Soro, Paola Valls, Gisela Alaman Laguarda, Pau Benavent, Vicente Chisbert Cuenca, Andreu Cueva, Matilde Lafuente, Asuncion Marques Parra, Alejandra Romero Rodrigo, Silvia Sanchez-Morcillo, Sergi Tormo, Francisco Javier Redondo, José Antonio De Andrés Ibanez, Lorena Gómez Diago, Maria José Hernández Cádiz, Granell Gil Manuel, Raquel Peris, Cristina Saiz, Jose Tatay Vivo, Maria Teresa Tebar Soto, Tamara Brunete, David Cancho, David R. Delgado García, Diana Zamudio, Santiago Garcia Del Valle, M. Luz Serrano, Eduardo Alonso, Victor Anillo, Emilio Maseda, Patricia Salgado, Luis Suarez, Alejandro Suarez-de-la-Rica, María José Villagrán, José Ignacio Alonso, Estefania Cabezuelo, Irene Garcia-Saiz, Olga Lopez del Moral, Silvia Martín, Alba Perez Gonzalez, Ma Sherezade Tovar Doncel, Martin Agüero Vera, Francisco José Ávila Sánchez, Beatriz Castaño, Beatriz Castaño Moreira, Sahely Flores Risco, Daniel Paz Martín, Fernando Pérez Martín, Paloma Poza, Adela Ruiz, Wilson Fabio Serna Martínez, Bárbara Vázquez Vicente, Saul Velaz Dominguez, Salvador Fernández, Alfonso Munoz-López, Maria Jose Bernat, Arantxa Mas, Kenneth Planas, Monir Jawad, Yousif Saeed, Annika Hedin, Helena Levander, Sandra Holmström, David Lönn, Frank Zoerner, Irene Åkring, Carl Widmark, Jan Zettergren, Victor Aspelund Liljequist, Lena Nystrom, Suzanne Odeberg-Wernerman, Anders Oldner, Malin Jonsson Fagerlund, Patrik Reje, Sara Lyckner, Jesper Sperber, Anne Adolfsson, Bengt Klarin, Katrin Ögren, Jean-Pierre Barras, Thomas Bührer, Vasileios Despotidis, Naeder Helmy, Stephan Holliger, Dimitri Aristotle Raptis, Roger Schmid, Antoine Meyer, Yves Jaquet, Ulf Kessler, Mirza Muradbegovic, Solange R. 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Rubio, C., Artiles, T.S., Soro, M., Valls, P., Laguarda, G.A., Benavent, P., Cuenca, V.C., Cueva, A., Lafuente, M., Parra, A.M., Rodrigo, A.R., Sanchez-Morcillo, S., Tormo, S., Redondo, F.J., De Andrés Ibanez, J.A., Diago, L.G., José Hernández Cádiz, M., Manuel, G.G., Peris, R., Saiz, C., Vivo, J.T., Soto, MTT, Brunete, T., Cancho, D., Delgado García, D.R., Zamudio, D., Del Valle, S.G., Serrano, M.L., Alonso, E., Anillo, V., Maseda, E., Salgado, P., Suarez, L., Suarez-de-la-Rica, A., Villagrán, M.J., Alonso, J.I., Cabezuelo, E., Garcia-Saiz, I., Lopez Del Moral, O., Martín, S., Gonzalez, A.P., Doncel, MST, Vera, M.A., José Ávila Sánchez, F., Castaño, B., Moreira, B.C., Risco, S.F., Martín, D.P., Martín, F.P., Poza, P., Ruiz, A., Serna Martínez, W.F., Vicente, B.V., Dominguez, S.V., Fernández, S., Munoz-López, A., Bernat, M.J., Mas, A., Planas, K., Jawad, M., Saeed, Y., Hedin, A., Levander, H., Holmström, S., Lönn, D., Zoerner, F., Åkring, I., Widmark, C., Zettergren, J., Liljequist, V.A., Nystrom, L., Odeberg-Wernerman, S., Oldner, A., Fagerlund, M.J., Reje, P., Lyckner, S., Sperber, J., Adolfsson, A., Klarin, B., Ögren, K., Barras, J.P., Bührer, T., Despotidis, V., Helmy, N., Holliger, S., Raptis, D.A., Schmid, R., Meyer, A., Jaquet, Y., Kessler, U., Muradbegovic, M., Nahum, S.R., Rotunno, T., Schiltz, B., Voruz, F., Worreth, M., Christoforidis, D., Popeskou, S.G., Furrer, M., Prevost, G.A., Stocker, A., Lang, K., Breitenstein, S., Ganter, M.T., Geisen, M., Soll, C., Korkmaz, M., Lubach, I., Schmitz, M., Meyer Zu Schwabedissen, M., Moritz, MZS, Zingg, U., Hillermann, T., Wildi, S., Pinto, B.B., Walder, B., Mariotti, G., Slankamenac, K., Namuyuga, M., Kyomugisha, E., Kituuka, O., Shikanda, A.W., Kakembo, N., Tom, C.O., Antonina, W., Bua, E., Ssettabi, E.M., Epodoi, J., Kabagenyi, F., Kirya, F., Dempsey, G., Seasman, C., Nawaz Khan, R.B., Kurasz, C., Macgregor, M., Shawki, B., Francis, D., Hariharan, V., Chau, S., Ellis, K., Butt, G., Chicken, D.W., Christmas, N., Allen, S., Daniel, G.D., Dempster, A., Kemp, J., Matthews, L., Mcglone, P., Tambellini, J., Trodd, D., Freitas, K., Garg, A., Gupta, J.K., Karpate, S., O'Hara, C., Troko, J., Angus, K., Bradley, J., Brennan, E., Brooks, C., Brown, J., Brown, G., Finch, A., Gratrix, K., Hesketh, S., Hill, G., Jeffs, C., Morgan, M., Pemberton, C., Slawson, N., Spickett, H., Swarbrick, G., Van Duyvenvoorde, G., Brennan, A., Briscoe, R., Cooper, S., Lawton, T., Northey, M., Senaratne, R., Stanworth, H., Burrows, L., Cain, H., Craven, R., Davies, K., Jonas, A., Pachucki, M., Walkden, G., Davies, H., Gudaca, M., Hobrok, M., Arawwawala, D., Fergey, L., Gardiner, M., Gunn, J., Johnson, L., Lofting, A., Lyle, A., Neela, F.M., Smolen, S., Topliffe, J., Williams, S., Bland, M., Balaji, P., Kaura, V., Lanka, P., Ahmed, A., Myatt, J., Shenoy, R., Soon, W.C., Tan, J., Karadia, S., Self, J., Durant, E., Tripathi, S., Bullock, C., Ghosh, A., Hughes, T., Zsisku, L., Bengeri, S., Cowton, A., Khalid, M.S., Limb, J., McAdam, C., Porritt, M., Rafi, M.A., Shekar, P., Adams, D., Harden, C., Hollands, H., King, A., March, L., Minto, G., Patrick, A., Squire, R., Waugh, D., Kumara, P., Simeson, K., Yarwood, J., Browning, J., Hatton, J., Julian, H., Mitra, A., Newton, M., Pernu, P.K., Wilson, A., Commey, T., Foot, H., Glover, L., Gupta, A., Lancaster, N., Levin, J., Mackenzie, F., Mestanza, C., Nofal, E., Pout, L., Varden, R., Wild, J., Jones, S., Moreton, S., Pulletz, M., Davies, C., Martin, M., Thomas, S., Burns, K., McArthur, C., Patel, P., Lau, G., Rich, N., Davis, F., Lyons, R., Port, B., Prout, R., Smith, C., Adelaja, Y., Bennett, V., Bidd, H., Dumitrescu, A., Murphy, J.F., Keen, A., Mguni, N., Ong, C., Adams, G., Boshier, P., Brown, R., Butryn, I., Chatterjee, J., Freethy, A., Lockwood, G., Tsakok, M., Tsiligiannis, S., Peat, W., Stephenson, L., Bradburn, M., Pick, S., Cunha, P., Olagbaiye, O., Tayeh, S., Packianathaswamy, B., Abernethy, C., Balasubramaniam, M., Bennett, R., Bolton, D., Martinson, V., Naylor, C., Bell, S., Heather, B., Kushakovsky, V., Alcock, L., Alexander, H., Anderson, C., Baker, P., Brookes, M., Cawthorn, L., Cirstea, E., Clarkson, R., Colling, K., Coulter, I., Das, S., Haigh, K., Hamdan, A., Hugill, K., Kottam, L., Lisseter, E., Mawdsley, M., McGivern, J., Padala, K., Phelps, V., Ramesh Kumar, V., Stewart, K., Towse, K., Tregonning, J., Vahedi, A., Walker, A., Baines, D., Bilolikar, A., Chande, S., Copley, E., Dunk, N., Kulkarni, R., Kumar, P., Metodiev, Y., Ncomanzi, D., Raithatha, B., Raymode, P., Szafranski, J., Twohey, L., Watt, P., Weatherall, L., Weatherill, J., Whitman, Z., Wighton, E., Abayasinghe, C., Chan, A., Darwish, S., Gill, J., Glasgow, E., Hadfield, D., Harris, C., Hopkins, P., Kochhar, A., Kunst, G., Mellis, C., Pool, A., Riozzi, P., Selman, A., Smith, E.J., Vele, L., Gercek, Y., Guy, K., Holden, D., Watson, N., Whysall, K., Andreou, P., Hales, D., Thompson, J., Bowrey, S., McDonald, S., Gilmore, J., Hills, V., Kelly, C., Kelly, S., Lloyd, G., Abbott, T., Gall, L., Torrance, H., Vivian, M., Berntsen, E., Nolan, T., Turner, A., Vohra, A., Brown, A., Clark, R., Coughlan, E., Daniel, C., Patvardhan, C., Pearson, R., Predeep, S., Saad, H., Shanmugam, M., Varley, S., Wylie, K., Cooper, L., Makowski, A., Misztal, B., Moldovan, E., Pegg, C., Donovan, A., Foot, J., Large, S., Claxton, A., Netke, B., Armstrong, R., Calderwood, C., Kwok, A., Mohr, O., Oyeniyi, P., Patnaik, L., Post, B., Ali, S., Arshad, H., Baker, G., Brenner, L., Brincat, M., Brunswicker, A., Cox, H., Cozar, O.I., Cheong, E., Durst, A., Fengas, L., Flatt, J., Glister, G., Narwani, V., Photi, E., Rankin, A., Rosbergen, M., Beaton, C., Horn, R., Hunt, J., Rousseau, G., Stancombe, L., Absar, M., Allsop, J., Drinkwater, Z., Hodgkiss, T., Smith, K., Alexander-Sefre, F., Campey, L., Dudgeon, L., Hall, K., Hitchcock, R., James, L., Winstone, U., Ahmad, N., Bauchmuller, K., Harrison, J., Jeffery, H., Miller, D., Pinder, A., Pothuneedi, S., Rosser, J., Sanghera, S., Swift, D., Walker, R., Bester, D., Cavanagh, S., Cripps, H., Daniel, H., Lynch, J., Pyke, S., Scholefield, J., Whitworth, H., Bottrill, F., Ramalingam, G., Webb, S., Akerman, N., Antill, P., Bourner, L., Buckley, S., Castle, G., Charles, R., Eggleston, C., Foster, R., Gill, S., Lindley, K., Lklouk, M., Lowery, T., Martin, O., Milne, D., O'Connor, P., Ratcliffe, A., Rose, A., Smith, A., Varma, S., Ward, J., Barcraft-Barnes, H., Camsooksai, J., Colvin, C., Reschreiter, H., Tbaily, L., Venner, N., Hamilton, C., Kelly, L., Toth-Tarsoly, P., Dodsworth, K., Foord, D., Gordon, P., Hawes, E., Lamb, N., Mouland, J., Nightingale, J., Rose, S., Schrieber, J., Al'Amri, K., Aladin, H., Arshad, M.A., Barraclough, J., Bentley, C., Bergin, C., Carrera, R., Clarkson, A., Collins, M., Denham, S., Griffiths, E., Ip, P., Jeyanthan, S., Joory, K., Kaur, S., Marriott, P., Mitchell, N., Nagaiah, S., Nilsson, A., Parekh, N., Pope, M., Seager, J., Serag, H., Tameem, A., Thomas, A., Thunder, J., Torrance, A., Vohra, R., Whitehouse, A., Wong, T., Blunt, M., Wong, K., Giles, J., Reed, I., Weller, D., Bell, G., Birch, J., Damant, R., Maiden, J., Mewies, C., Prince, C., Radford, J., Reynolds, T., Balain, B., Banerjee, R., Barnett, A., Burston, B., Edwards, J., Evans, C., Ford, D., Gallacher, P., Hill, S., Jaffray, D., Karlakki, S., Kennedy, J., Kiely, N., Lewthwaite, S., Marquis, C., Ockendon, M., Phillips, S., Pickard, S., Richardson, J., Roach, R., Smith, T., Spencer-Jones, R., Steele, N., Steen, J., Van Liefland, M., White, S., Faulds, M., Harris, M., Nicol, S., Pearson, S.A., Chukkambotla, S., Andrew, A., Attrill, E., Campbell, G., Datson, A., Fouracres, A., Graterol, J., Graves, L., Hong, B., Ishimaru, A., Karthikeyan, A., King, H., Lawson, T., Lee, G., Lyons, S., Hall, A.M., Mathoulin, S., Mcintyre, E., Mclaughlin, D., Mulcahy, K., Paddle, J., Robbins, J., Sung, W., Tayo, A., Trembath, L., Venugopal, S., Wigmore, G., Boereboom, C., Downes, C., Humphries, R., Melbourne, S., Tou, S., Ullah, S., Batchelor, N., Boxall, L., Broomby, R., Deen, T., Hellewell, A., Helliwell, L., Hutchings, M., Hutchins, D., Keenan, S., Mackie, D., Potter, A., Smith, F., Stone, L., Thorpe, K., Wassall, R., Woodgate, A., Baillie, S., Campbell, T., James, S., King, C., Marques de Araujo, D., Martin, D., Morkane, C., Neely, J., Rajendram, R., Burton, M., James, K., Keevil, E., Minik, O., Morgan, J., Musgrave, A., Rajanna, H., Roberts, T., Adamson, M., Jumbe, S., Kendall, J., Muthuswamy, M.B., Cruikshanks, A., Wrench, I., Zeidan, L., Ardern, D., Harris, B., Hellstrom, J., Martin, J., Thomas, R., Varsani, N., Brown, C.W., Docherty, P., Gillies, M., McGregor, E., Usher, H., Craig, J., Ahmad, T., Bodger, P., Creary, T., Fowler, A., Ijuo, E., Jones, T., Kantsedikas, I., Lahiri, S., McLean, A.L., Niebrzegowska, E., Phull, M., Wickboldt, N., Baldwin, J., Doyle, D., Mcmullan, S., Oladapo, M., Owen, T., Williams, A., Gregory, P., Husain, T., Kirk-Bayley, J., Mathers, E., Montague, L., Harper, M., Jack, J., Ridley, C., Avis, J., Cook, T., Dali-Kemmery, L., Kerslake, I., Lambourne, V., Pearson, A., Boyd, C., Callaghan, M., Lawson, C., McCrossan, R., Nesbitt, V., O'connor, L., Sinclair, R., Farid, N., Morgese, C., Bhatia, K., Karmarkar, S., Ahmed, J., Branagan, G., Hutton, M., Swain, A., Brookes, J., Cornell, J., Dolan, R., Hulme, J., Jansen van Vuuren, A., Jowitt, T., Kalashetty, G., Lloyd, F., Patel, K., Sherwood, N., Brown, L., Chandler, B., Deighton, K., Emma, T., Haunch, K., Cheeseman, M., Dent, K., Gray, C., Hood, M., Jones, D., Juj, J., Rao, R., Walker, T., Al Anizi, M., Cheah, C., Cheing, Y., Coutinho, F., Gondo, P., Hadebe, B., Hove, M.O., Khader, A., Krishnachetty, B., Rhodes, K., Sokhi, J., Baker, K.A., Bertram, W., Looseley, A., Mouton, R., Hanna, G., Arnold, G., Arya, S., Balfoussia, D., Baxter, L., Harris, J., Jones, C., Knaggs, A., Markar, S., Perera, A., Scott, A., Shida, A., Sirha, R., Wright, S., Frost, V., Andrews, E., Arrandale, L., Barrett, S., Cifra, E., Cooper, M., Dragnea, D., Elna, C., Maclean, J., Meier, S., Milliken, D., Munns, C., Ratanshi, N., Ramessur, S., Salvana, A., Watson, A., Ali, H., Critchley, R., Endersby, S., Hicks, C., Liddle, A., Pass, M., Ritchie, C., Thomas, C., Too, L., Welsh, S., Gill, T., Johnson, J., Reed, J., Davis, E., Papadopoullos, S., Attwood, C., Biffen, A., Boulton, K., Gray, S., Hay, D., Mills, S., Montgomery, J., Riddell, R., Simpson, J., Bhardwaj, N., Paul, E., Uwubamwen, N., Alexander, M., Arrich, J., Arumugam, S., Blackwood, D., Boggiano, V., Chan, Y.L., Chatterjee, D., Chhabra, A., Christian, R., Costelloe, H., Matthewman, M.C., Dalton, E., Darko, J., Davari, M., Dave, T., Deacon, M., Deepak, S., Edmond, H., Ellis, J., El-Sayed, A., Eneje, P., English, R., Ewe, R., Foers, W., Franklin, J., Gallego, L., Garrett, E., Goldberg, O., Goss, H., Greaves, R., Harris, R., Hennings, C., Jones, E., Kamali, N., Kokkinos, N., Lewis, C., Lignos, L., Malgapo, E.V., Malik, R., Milne, A., Mulligan, J.P., Nicklin, P., Palipane, N., Parsons, T., Piper, R., Prakash, R., Ramesh, B., Rasip, S., Reading, J., Rela, M., Reyes, A., Stephens, R., Rooms, M., Shah, K., Simons, H., Solanki, S., Spowart, E., Stevens, A., Waggett, H., Yassaee, A., Kennedy, A., Scott, S., Somanath, S., Berg, A., Hernandez, M., Nanda, R., Tank, G., Wilson, N., Wilson, D., Al-Soudaine, Y., Baldwin, M., Cornish, J., Davies, Z., Davies, L., Edwards, M., Frewer, N., Gallard, S., Glasbey, J., Harries, R., Hopkins, L., Kim, T., Koompirochana, V., Lawson, S., Lewis, M., Makzal, Z., Scourfield, S., Ahmad, Y., Bates, S., Blackwell, C., Bryant, H., Collins, H., Coulter, S., Cruickshank, R., Daniel, S., Daubeny, T., Golder, K., Hawkins, L., Helen, B., Hinxman, H., Levett, D., Salmon, K., Seaward, L., Skinner, B., Tyrell, B., Wadams, B., Walsgrove, J., Dickson, J., Constantin, K., Karen, M., O'Brien, P., O'Donohoe, L., Payne, H., Sundayi, S., Walker, E., Brooke, J., Cardy, J., Humphreys, S., Kessack, L., Kubitzek, C., Kumar, S., Cotterill, D., Hodzovic, E., Hosdurga, G., Miles, E., Saunders, G., Campbell, M., Chan, P., Jemmett, K., Raj, A., Naik, A., Oshowo, A., Ramamoorthy, R., Shah, N., Sylvan, A., Blyth, K., Burtenshaw, A., Freeman, D., Johnson, E., Lo, P., Martin, T., Plunkett, E., Wollaston, J., Allison, J., Carroll, C., Craw, N., Craw, S., Pitt-Kerby, T., Rowland-Axe, R., Spurdle, K., McDonald, A., Simon, D., Sinha, V., Banner-Goodspeed, V., Boone, M., Campbell, K., Lu, F., Scannell, J., Sobol, J., Balajonda, N., Clemmons, K., Conde, C., Elgasim, M., Funk, B., Hopkins, T., Olaleye, O., Omer, O., Pender, M., Porto, A., Waweru, P., Yeh, E., Bodansky, D., Evans, A., Kleopoulos, S., Maril, R., Mathney, E., Sanchez, A., Tinuoye, E., Bateman, B., Eng, K., Jiang, N., Ladha, K., Needleman, J., Chen, L.L., Lane, R., Robinowitz, D., Ghushe, N., Irshad, M., O'Connor, J., Patel, S., Takemoto, S., Wallace, A., Mazzeffi, M., Rock, P., Wallace, K., Chua, P., Mattera, M., Sharar, R., Thilen, S., Treggiari, M., Morgan, A., Sofjan, I., Subramaniam, K., Avidan, M., Maybrier, H., Muench, M., and Wildes, T.
Subjects: Male, Postoperative Complications/epidemiology, Hospital mortality, [SDV]Life Sciences [q-bio], surgery, Postoperative Complications, 0302 clinical medicine, cohort studies, 030202 anesthesiology, patient safety, 030212 general & internal medicine, Postoperative Period, Medicine(all), Middle Aged, Checklist, 3. Good health, Treatment Outcome, operative/mortality, Elective Surgical Procedures, Surgical Procedures, Operative, Meta-analysis, Cohort, Cohort studies, Female, Elective Surgical Procedure, postoperative care/methods, postoperative care/statistics and numerical data, surgical procedures, Anesthesiology and Pain Medicine, Cohort study, Adult, medicine.medical_specialty, Evidence-based medicine, NO, 03 medical and health sciences, Patient safety, medicine, postoperative care/method, Humans, Elective Surgical Procedures/standards, Aged, Cohort Studies, Evidence-Based Medicine, Hospital Mortality, Patient Safety, Postoperative Complications/mortality, Postoperative Complications/prevention & control, Surgical Procedures, Operative/methods, business.industry, Odds ratio, Surgery, Observational study, business, cohort studie
Abstract: BACKGROUND: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool.METHODS: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals.RESULTS: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32-0.77); PCONCLUSIONS: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine.
Published: 2018

29. Nonparametric Estimation for Stochastic Processes Driven by Alpha-stable Processes of the Second Kind.

Author: Shanlin Wan, Zhiqiang Jiang, and Xuekang Zhang
Subjects: *NONPARAMETRIC estimation, *STOCHASTIC processes, *ASYMPTOTIC distribution
Abstract: The present paper deals with the problem of nonparametric estimation for stochastic processes driven by alpha-stable processes of the second kind. The consistency and the asymptotic distribution of the nonparametric estimator are discussed. [ABSTRACT FROM AUTHOR]
Published: 2024

30. Ergodicity of stochastic smoking model and parameter estimation

Author: Mei Dong, Xuekang Zhang, Jinying Tong, and Zhenzhong Zhang
Subjects: Algebra and Number Theory, Stationary distribution, Statistics::Applications, Physics::Instrumentation and Detectors, Estimation theory, Astrophysics::High Energy Astrophysical Phenomena, Applied Mathematics, Ergodicity, Mathematical analysis, Stationary ergodic process, 01 natural sciences, Quadratic variation, 010101 applied mathematics, Stochastic partial differential equation, 010104 statistics & probability, Computer Science::Systems and Control, Ergodic theory, Applied mathematics, 0101 mathematics, Analysis, Brownian motion, Mathematics
Abstract: In this paper, we first propose a stochastic smoking model driven by Brownian motion based on a deterministic smoking model. We show that when the coefficients of the noise are small, the smoking model is ergodic. We then estimate the drift coefficients of stochastic smoking model by a least squares estimation and the ergodic theory on the stationary distribution. Finally, we develop a new approach to estimating the diffusion coefficients. Computer simulations will be used to illustrate our theory.
Published: 2016

31. Contents of Heavy Metals in Typical Aquatic Products from a Market in Binzhou.

Author: Xuekang ZHANG, Zaiwang ZHANG, Zhuang REN, Linlin ZHAO, Hui YU, and Shenqiang ZHAI
Abstract: To evaluate the levels of heavy metal pollution and risks in consumption of aquatic products from a market in Binzhou, the contents of Cu, Zn, Cd, Cr and Pb in the edible part of eight aquatic species such as Ctenopharyngodon idellus were determined by inductively coupled plasma mass spectrometry. The results show that the levels of the five elements differed among different species of aquatic products. The ability of bivalves to accumulate heavy metals was significantly higher than that of fish. Compared with relevant food hygiene standards, there was a certain excess of Cr in Ruditapes philippinarum and Penaeus vannamei. The results of human exposure risk assessment show that the THQ values of the heavy metals in the eight aquatic species were all less than 1, indicating that the consumption of these aquatic products had no potential non-carcinogenic risks. [ABSTRACT FROM AUTHOR]
Published: 2019
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32. Effects of dexmedetomidine, propofol and etomidate on the intraoperative wake-up in the cerebral functional area under the guidance of entropy index

Author: Xinyan, Zhao, Zhengbang, Hu, Xuekang, Zhang, Qian, Hu, Qiong, Wu, Sisi, Liang, Xinhua, Fang, Shi, Shu, and Zhiyi, Liu
Abstract: Objective:The study observed the efficacy and safety of dexmedetomidine, propofol and etomidate on brain functional areas in patients undergoing wake-up brain surgery under the guidance of entropy index.Methods:Sixty patients undergoing wake-up brain surgery on brain functional areas were enrolled, and randomly divided into three groups: dexmedetomidine group (group D), propofol group (group P) and etomidate group (group E), 20 in each. The vital signs, entropy indices of each time point, wake-up time, wake-up quality and adverse reaction in the wake-up period were observed and compared.Results:There were no differences in the duration of wake-up, duration of anesthesia, duration of surgery and postoperative wake-up time between the three groups (P> 0.05). The wake-up quality in group D was significantly better than group P and group E (P <0.05), group P was better than group E (P <0.05). The incidence of adverse events in group D was lower than that in groups P and E (P <0.05). The incidence of adverse events in group P was lower than that in group E (P <0.05).Conclusion:Under the guidance of entropy index, anesthesia induced by dexmedetomidine, propofol and etomidate combined with remifentanil can safely and effectively be used to the wake-up brain functional areas surgery, but the wake-up quality with use of dexmedetomidine is highest, and the incidence of adverse events is the lowest during wake-up period.
Published: 2018
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33. Lidocaine induces neurotoxicity in spinal cord neurons in Goto-Kakizaki rats via AMPK-mediated mitophagy.

Author: Ling Chen, ChenLu Fan, Xuekang Zhang, Shibiao Chen, Lingling Ye, and Xiaolan Zheng
Subjects: *SPINAL cord, *LIDOCAINE, *NEUROTOXICOLOGY, *NEURONS, *AMP-activated protein kinases
Abstract: Objective. Lidocaine has been reported to induce neurotoxicity, which is further enhanced by high glucose levels. This study is aimed to explore the underlying mechanisms of lidocaine neurotoxicity in spinal cord neurons of diabetes. Methods. Take thirty specific pathogen-free (SPF) healthy Sprague-Dawley (SD) rats and thirty Goto-Kakizaki (GK) rats, aged 12 weeks, weighing 180-200 g. The spinal cord neurons of rats were isolated and cultured in vitro. Cell Counting Kit-8 was used to detect cell proliferation to determine the appropriate concentration and duration of lidocaine. Mitochondrial function was assessed using ATP content, cellular oxygen consumption rate, mitochondrial membrane potential, ROS production, and mitochondrial ultrastructure. Western blot was applied to detect the expression of autophagy- and mitophagy-related molecules PINK1, p-AMPK, LC-3II/LC3-I ratio and mTORC1. Immunofluorescent staining was used to detect the expression of PINK1 and LC3. Results. Lidocaine decreased cell viability of spinal cord neurons in concentration- and time-dependent manners. And lidocaine treatment aggravated mitochondrial dysfunction in GK rats. Furthermore, mitophagy was activated in diabetes, and lidocaine exposure up-regulated mitophagy. AMPK activator MK8722 aggravated mitochondrial damage, increased the expression of PINK1, p-AMPK, LC-3II/LC3- I ratio, and decreased the expression of mTORC1, while AMPK inhibitor Compound C and autophagy inhibitor Bafilomycin A1 reduced mitochondrial damage and decreased the expression of PINK1, p-AMPK, LC-3II/LC3-I ratio, and increased the expression of mTORC1. Conclusions. Lidocaine induced neurotoxicity of spinal cord neurons in GK rats via AMPK-mediated mitophagy. [ABSTRACT FROM AUTHOR]
Published: 2023
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33 results on '"Xuekang Zhang"'

1. Optimal mean-variance investment and reinsurance strategies with a general Lévy process risk model

2. Dynamical analysis of a heterogeneous spatial diffusion Zika model with vector-bias and environmental transmission

3. E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis

4. Research on fault diagnosis of time-domain vibration signal based on convolutional neural networks

5. The Emerging Roles of Tripartite Motif Proteins (TRIMs) in Acute Lung Injury

6. The valuation of options on discrete dividend-paying stocks

7. Stability of stochastic Gilpin-Ayala model driven by α-stable process under regime switching

8. Effects of remimazolam on cerebral oxygen saturation and postoperative cognitive function in elderly undergoing nasal endoscopic surgery: a retrospective exploratory study

9. Asymptotic behavior of maximum likelihood estimators for Ornstein–Uhlenbeck process with large linear drift

10. Parameter Estimation for Ornstein–Uhlenbeck Driven by Ornstein–Uhlenbeck Processes with Small Lévy Noises

11. Optimal portfolio and reinsurance with two differential risky assets

12. Nonparametric estimation of periodic signal disturbed by α-stable noises

13. The Emerging Roles of Tripartite Motif Proteins (TRIMs) in Acute Lung Injury

14. Trajectory fitting estimation for a class of SDEs with small Lévy noises

15. Parameter estimation for integrated Ornstein–Uhlenbeck processes with small Lévy noises

16. Perioperative Pain Management With Bilateral Pecto-intercostal Fascial Block in Pediatric Patients Undergoing Open Cardiac Surgery

17. Option pricing under a Markov-modulated Merton jump-diffusion dividend

18. Parameter estimation for generalized Ait-Sahalia-type interest rate model

19. Dexmedetomidine reduces enteric glial cell injury induced by intestinal ischaemia-reperfusion injury through mitochondrial localization of TERT

20. Nonparametric estimation of the trend for stochastic differential equations driven by small α-stable noises

21. Parameter estimation for certain nonstationary processes driven by α-stable motions

22. Stabilization and destabilization of nonlinear stochastic differential delay equations

23. Option pricing under a Markov-modulated jump-diffusion dividend

24. MiR-520b promotes the progression of non-small cell lung cancer through activating Hedgehog pathway

25. Exponential ergodicity for population dynamics driven byα-stable processes

26. The a2AR/Caveolin-1/p38MAPK/NF-κB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia-reperfusion.

27. Parameter estimation for non-stationary reflected Ornstein–Uhlenbeck processes driven by α-stable noises

28. The surgical safety checklist and patient outcomes after surgery

29. Nonparametric Estimation for Stochastic Processes Driven by Alpha-stable Processes of the Second Kind.

30. Ergodicity of stochastic smoking model and parameter estimation

31. Contents of Heavy Metals in Typical Aquatic Products from a Market in Binzhou.

32. Effects of dexmedetomidine, propofol and etomidate on the intraoperative wake-up in the cerebral functional area under the guidance of entropy index

33. Lidocaine induces neurotoxicity in spinal cord neurons in Goto-Kakizaki rats via AMPK-mediated mitophagy.

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