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2. The AEGEAN-169 clade of bacterioplankton is synonymous with SAR11 subclade V (HIMB59) and metabolically distinct
- Author
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Eric W. Getz, V. Celeste Lanclos, Conner Y. Kojima, Chuankai Cheng, Michael W. Henson, Max Emil Schön, Thijs J. G. Ettema, Brant C. Faircloth, and J. Cameron Thrash
- Subjects
comparative genomics ,SAR11 ,AEGEAN-169 ,HIMB59 ,bacterioplankton ,Microbiology ,QR1-502 - Abstract
ABSTRACT Bacterioplankton of the SAR11 clade are the most abundant marine microorganisms and consist of numerous subclades spanning order-level divergence (Pelagibacterales). The assignment of the earliest diverging subclade V (a.k.a. HIMB59) to the Pelagibacterales is highly controversial, with multiple recent phylogenetic studies placing them completely separate from SAR11. Other than through phylogenomics, subclade V has not received detailed examination due to limited genomes from this group. Here, we assessed the ecogenomic characteristics of subclade V to better understand the role of this group in comparison to the Pelagibacterales. We used a new isolate genome, recently released single-amplified genomes and metagenome-assembled genomes, and previously established SAR11 genomes to perform a comprehensive comparative genomics analysis. We paired this analysis with the recruitment of metagenomes spanning the open ocean, coastal, and brackish systems. Phylogenomics, average amino acid identity, and 16S rRNA gene phylogeny indicate that SAR11 subclade V is synonymous with the ubiquitous AEGEAN-169 clade and support the contention that this group represents a taxonomic family. AEGEAN-169 shared many bulk genome qualities with SAR11, such as streamlining and low GC content, but genomes were generally larger. AEGEAN-169 had overlapping distributions with SAR11 but was metabolically distinct from SAR11 in its potential to transport and utilize a broader range of sugars as well as in the transport of trace metals and thiamin. Thus, regardless of the ultimate phylogenetic placement of AEGEAN-169, these organisms have distinct metabolic capacities that likely allow them to differentiate their niche from canonical SAR11 taxa. IMPORTANCE One goal of marine microbiologists is to uncover the roles various microorganisms are playing in biogeochemical cycles. Success in this endeavor relies on differentiating groups of microbes and circumscribing their relationships. An early-diverging group (subclade V) of the most abundant bacterioplankton, SAR11, has recently been proposed as a separate lineage that does not share a most recent common ancestor. But beyond phylogenetics, little has been done to evaluate how these organisms compare with SAR11. Our work leverages dozens of new genomes to demonstrate the similarities and differences between subclade V and SAR11. In our analysis, we also establish that subclade V is synonymous with a group of bacteria established from 16S rRNA gene sequences, AEGEAN-169. Subclade V/AEGEAN-169 has clear metabolic distinctions from SAR11 and their shared traits point to remarkable convergent evolution if they do not share a most recent common ancestor.
- Published
- 2023
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3. GWTC-3: Compact Binary Coalescences Observed by LIGO and Virgo during the Second Part of the Third Observing Run
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R. Abbott, T. D. Abbott, F. Acernese, K. Ackley, C. Adams, N. Adhikari, R. X. Adhikari, V. B. Adya, C. Affeldt, D. Agarwal, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, S. Akcay, T. Akutsu, S. Albanesi, A. Allocca, P. A. Altin, A. Amato, C. Anand, S. Anand, A. Ananyeva, S. B. Anderson, W. G. Anderson, M. Ando, T. Andrade, N. Andres, T. Andrić, S. V. Angelova, S. Ansoldi, J. M. Antelis, S. Antier, S. Appert, Koji Arai, Koya Arai, Y. Arai, S. Araki, A. Araya, M. C. Araya, J. S. Areeda, M. Arène, N. Aritomi, N. Arnaud, M. Arogeti, S. M. Aronson, K. G. Arun, H. Asada, Y. Asali, G. Ashton, Y. Aso, M. Assiduo, S. M. Aston, P. Astone, F. Aubin, C. Austin, S. Babak, F. Badaracco, M. K. M. Bader, C. Badger, S. Bae, Y. Bae, A. M. Baer, S. Bagnasco, Y. Bai, L. Baiotti, J. Baird, R. Bajpai, M. Ball, G. Ballardin, S. W. Ballmer, A. Balsamo, G. Baltus, S. Banagiri, D. Bankar, J. C. Barayoga, C. Barbieri, B. C. Barish, D. Barker, P. Barneo, F. Barone, B. Barr, L. Barsotti, M. Barsuglia, D. Barta, J. Bartlett, M. A. Barton, I. Bartos, R. Bassiri, A. Basti, M. Bawaj, J. C. Bayley, A. C. Baylor, M. Bazzan, B. Bécsy, V. M. Bedakihale, M. Bejger, I. Belahcene, V. Benedetto, D. Beniwal, T. F. Bennett, J. D. Bentley, M. BenYaala, F. Bergamin, B. K. Berger, S. Bernuzzi, C. P. L. Berry, D. Bersanetti, A. Bertolini, J. Betzwieser, D. Beveridge, R. Bhandare, U. Bhardwaj, D. Bhattacharjee, S. Bhaumik, I. A. Bilenko, G. Billingsley, S. Bini, R. Birney, O. Birnholtz, S. Biscans, M. Bischi, S. Biscoveanu, A. Bisht, B. Biswas, M. Bitossi, M.-A. Bizouard, J. K. Blackburn, C. D. Blair, D. G. Blair, R. M. Blair, F. Bobba, N. Bode, M. Boer, G. Bogaert, M. Boldrini, L. D. Bonavena, F. Bondu, E. Bonilla, R. Bonnand, P. Booker, B. A. Boom, R. Bork, V. Boschi, N. Bose, S. Bose, V. Bossilkov, V. Boudart, Y. Bouffanais, A. Bozzi, C. Bradaschia, P. R. Brady, A. Bramley, A. Branch, M. Branchesi, J. Brandt, J. E. Brau, M. Breschi, T. Briant, J. H. Briggs, A. Brillet, M. Brinkmann, P. Brockill, A. F. Brooks, J. Brooks, D. D. Brown, S. Brunett, G. Bruno, R. Bruntz, J. Bryant, T. Bulik, H. J. Bulten, A. Buonanno, R. Buscicchio, D. Buskulic, C. Buy, R. L. Byer, G. S. Cabourn Davies, L. Cadonati, G. Cagnoli, C. Cahillane, J. Calderón Bustillo, J. D. Callaghan, T. A. Callister, E. Calloni, J. Cameron, J. B. Camp, M. Canepa, S. Canevarolo, M. Cannavacciuolo, K. C. Cannon, H. Cao, Z. Cao, E. Capocasa, E. Capote, G. Carapella, F. Carbognani, J. B. Carlin, M. F. Carney, M. Carpinelli, G. Carrillo, G. Carullo, T. L. Carver, J. Casanueva Diaz, C. Casentini, G. Castaldi, S. Caudill, M. Cavaglià, F. Cavalier, R. Cavalieri, M. Ceasar, G. Cella, P. Cerdá-Durán, E. Cesarini, W. Chaibi, K. Chakravarti, S. Chalathadka Subrahmanya, E. Champion, C.-H. Chan, C. Chan, C. L. Chan, K. Chan, M. Chan, K. Chandra, P. Chanial, S. Chao, C. E. A. Chapman-Bird, P. Charlton, E. A. Chase, E. Chassande-Mottin, C. Chatterjee, Debarati Chatterjee, Deep Chatterjee, M. Chaturvedi, S. Chaty, K. Chatziioannou, C. Chen, H. Y. Chen, J. Chen, K. Chen, X. Chen, Y.-B. Chen, Y.-R. Chen, Z. Chen, H. Cheng, C. K. Cheong, H. Y. Cheung, H. Y. Chia, F. Chiadini, C-Y. Chiang, G. Chiarini, R. Chierici, A. Chincarini, M. L. Chiofalo, A. Chiummo, G. Cho, H. S. Cho, R. K. Choudhary, S. Choudhary, N. Christensen, H. Chu, Q. Chu, Y-K. Chu, S. Chua, K. W. Chung, G. Ciani, P. Ciecielag, M. Cieślar, M. Cifaldi, A. A. Ciobanu, R. Ciolfi, F. Cipriano, A. Cirone, F. Clara, E. N. Clark, J. A. Clark, L. Clarke, P. Clearwater, S. Clesse, F. Cleva, E. Coccia, E. Codazzo, P.-F. Cohadon, D. E. Cohen, L. Cohen, M. Colleoni, C. G. Collette, A. Colombo, M. Colpi, C. M. Compton, M. Constancio, Jr., L. Conti, S. J. Cooper, P. Corban, T. R. Corbitt, I. Cordero-Carrión, S. Corezzi, K. R. Corley, N. Cornish, D. Corre, A. Corsi, S. Cortese, C. A. Costa, R. Cotesta, M. W. Coughlin, J.-P. Coulon, S. T. Countryman, B. Cousins, P. Couvares, D. M. Coward, M. J. Cowart, D. C. Coyne, R. Coyne, J. D. E. Creighton, T. D. Creighton, A. W. Criswell, M. Croquette, S. G. Crowder, J. R. Cudell, T. J. Cullen, A. Cumming, R. Cummings, L. Cunningham, E. Cuoco, M. Curyło, P. Dabadie, T. Dal Canton, S. Dall’Osso, G. Dálya, A. Dana, L. M. DaneshgaranBajastani, B. D’Angelo, B. Danila, S. Danilishin, S. D’Antonio, K. Danzmann, C. Darsow-Fromm, A. Dasgupta, L. E. H. Datrier, V. Dattilo, I. Dave, M. Davier, D. Davis, M. C. Davis, E. J. Daw, P. F. de Alarcón, R. Dean, D. DeBra, M. Deenadayalan, J. Degallaix, M. De Laurentis, S. Deléglise, V. Del Favero, F. De Lillo, N. De Lillo, W. Del Pozzo, L. M. DeMarchi, F. De Matteis, V. D’Emilio, N. Demos, T. Dent, A. Depasse, R. De Pietri, R. De Rosa, C. De Rossi, R. DeSalvo, R. De Simone, S. Dhurandhar, M. C. Díaz, M. Diaz-Ortiz, Jr., N. A. Didio, T. Dietrich, L. Di Fiore, C. Di Fronzo, C. Di Giorgio, F. Di Giovanni, M. Di Giovanni, T. Di Girolamo, A. Di Lieto, B. Ding, S. Di Pace, I. Di Palma, F. Di Renzo, A. K. Divakarla, A. Dmitriev, Z. Doctor, L. D’Onofrio, F. Donovan, K. L. Dooley, S. Doravari, I. Dorrington, M. Drago, J. C. Driggers, Y. Drori, J.-G. Ducoin, P. Dupej, O. Durante, D. D’Urso, P.-A. Duverne, S. E. Dwyer, C. Eassa, P. J. Easter, M. Ebersold, T. Eckhardt, G. Eddolls, B. Edelman, T. B. Edo, O. Edy, A. Effler, S. Eguchi, J. Eichholz, S. S. Eikenberry, M. Eisenmann, R. A. Eisenstein, A. Ejlli, E. Engelby, Y. Enomoto, L. Errico, R. C. Essick, H. Estellés, D. Estevez, Z. Etienne, T. Etzel, M. Evans, T. M. Evans, B. E. Ewing, V. Fafone, H. Fair, S. Fairhurst, A. M. Farah, S. Farinon, B. Farr, W. M. Farr, N. W. Farrow, E. J. Fauchon-Jones, G. Favaro, M. Favata, M. Fays, M. Fazio, J. Feicht, M. M. Fejer, E. Fenyvesi, D. L. Ferguson, A. Fernandez-Galiana, I. Ferrante, T. A. Ferreira, F. Fidecaro, P. Figura, I. Fiori, M. Fishbach, R. P. Fisher, R. Fittipaldi, V. Fiumara, R. Flaminio, E. Floden, H. Fong, J. A. Font, B. Fornal, P. W. F. Forsyth, A. Franke, S. Frasca, F. Frasconi, C. Frederick, J. P. Freed, Z. Frei, A. Freise, R. Frey, P. Fritschel, V. V. Frolov, G. G. Fronzé, Y. Fujii, Y. Fujikawa, M. Fukunaga, M. Fukushima, P. Fulda, M. Fyffe, H. A. Gabbard, W. E. Gabella, B. U. Gadre, J. R. Gair, J. Gais, S. Galaudage, R. Gamba, D. Ganapathy, A. Ganguly, D. Gao, S. G. Gaonkar, B. Garaventa, F. García, C. García-Núñez, C. García-Quirós, F. Garufi, B. Gateley, S. Gaudio, V. Gayathri, G.-G. Ge, G. Gemme, A. Gennai, J. George, R. N. George, O. Gerberding, L. Gergely, P. Gewecke, S. Ghonge, Abhirup Ghosh, Archisman Ghosh, Shaon Ghosh, Shrobana Ghosh, B. Giacomazzo, L. Giacoppo, J. A. Giaime, K. D. Giardina, D. R. Gibson, C. Gier, M. Giesler, P. Giri, F. Gissi, J. Glanzer, A. E. Gleckl, P. Godwin, E. Goetz, R. Goetz, N. Gohlke, J. Golomb, B. Goncharov, G. González, A. Gopakumar, M. Gosselin, R. Gouaty, D. W. Gould, B. Grace, A. Grado, M. Granata, V. Granata, A. Grant, S. Gras, P. Grassia, C. Gray, R. Gray, G. Greco, A. C. Green, R. Green, A. M. Gretarsson, E. M. Gretarsson, D. Griffith, W. Griffiths, H. L. Griggs, G. Grignani, A. Grimaldi, S. J. Grimm, H. Grote, S. Grunewald, P. Gruning, D. Guerra, G. M. Guidi, A. R. Guimaraes, G. Guixé, H. K. Gulati, H.-K. Guo, Y. Guo, Anchal Gupta, Anuradha Gupta, P. Gupta, E. K. Gustafson, R. Gustafson, F. Guzman, S. Ha, L. Haegel, A. Hagiwara, S. Haino, O. Halim, E. D. Hall, E. Z. Hamilton, G. Hammond, W.-B. Han, M. Haney, J. Hanks, C. Hanna, M. D. Hannam, O. Hannuksela, H. Hansen, T. J. Hansen, J. Hanson, T. Harder, T. Hardwick, K. Haris, J. Harms, G. M. Harry, I. W. Harry, D. Hartwig, K. Hasegawa, B. Haskell, R. K. Hasskew, C.-J. Haster, K. Hattori, K. Haughian, H. Hayakawa, K. Hayama, F. J. Hayes, J. Healy, A. Heidmann, A. Heidt, M. C. Heintze, J. Heinze, J. Heinzel, H. Heitmann, F. Hellman, P. Hello, A. F. Helmling-Cornell, G. Hemming, M. Hendry, I. S. Heng, E. Hennes, J. Hennig, M. H. Hennig, A. G. Hernandez, F. Hernandez Vivanco, M. Heurs, S. Hild, P. Hill, Y. Himemoto, A. S. Hines, Y. Hiranuma, N. Hirata, E. Hirose, S. Hochheim, D. Hofman, J. N. Hohmann, D. G. Holcomb, N. A. Holland, K. Holley-Bockelmann, I. J. Hollows, Z. J. Holmes, K. Holt, D. E. Holz, Z. Hong, P. Hopkins, J. Hough, S. Hourihane, E. J. Howell, C. G. Hoy, D. Hoyland, A. Hreibi, B-H. Hsieh, Y. Hsu, G-Z. Huang, H-Y. Huang, P. Huang, Y-C. Huang, Y.-J. Huang, Y. Huang, M. T. Hübner, A. D. Huddart, B. Hughey, D. C. Y. Hui, V. Hui, S. Husa, S. H. Huttner, R. Huxford, T. Huynh-Dinh, S. Ide, B. Idzkowski, A. Iess, B. Ikenoue, S. Imam, K. Inayoshi, C. Ingram, Y. Inoue, K. Ioka, M. Isi, K. Isleif, K. Ito, Y. Itoh, B. R. Iyer, K. Izumi, V. JaberianHamedan, T. Jacqmin, S. J. Jadhav, S. P. Jadhav, A. L. James, A. Z. Jan, K. Jani, J. Janquart, K. Janssens, N. N. Janthalur, P. Jaranowski, D. Jariwala, R. Jaume, A. C. Jenkins, K. Jenner, C. Jeon, M. Jeunon, W. Jia, H.-B. Jin, G. R. Johns, N. K. Johnson-McDaniel, A. W. Jones, D. I. Jones, J. D. Jones, P. Jones, R. Jones, R. J. G. Jonker, L. Ju, P. Jung, K. Jung, J. Junker, V. Juste, K. Kaihotsu, T. Kajita, M. Kakizaki, C. V. Kalaghatgi, V. Kalogera, B. Kamai, M. Kamiizumi, N. Kanda, S. Kandhasamy, G. Kang, J. B. Kanner, Y. Kao, S. J. Kapadia, D. P. Kapasi, S. Karat, C. Karathanasis, S. Karki, R. Kashyap, M. Kasprzack, W. Kastaun, S. Katsanevas, E. Katsavounidis, W. Katzman, T. Kaur, K. Kawabe, K. Kawaguchi, N. Kawai, T. Kawasaki, F. Kéfélian, D. Keitel, J. S. Key, S. Khadka, F. Y. Khalili, S. Khan, E. A. Khazanov, N. Khetan, M. Khursheed, N. Kijbunchoo, C. Kim, J. C. Kim, J. Kim, K. Kim, W. S. Kim, Y.-M. Kim, C. Kimball, N. Kimura, M. Kinley-Hanlon, R. Kirchhoff, J. S. Kissel, N. Kita, H. Kitazawa, L. Kleybolte, S. Klimenko, A. M. Knee, T. D. Knowles, E. Knyazev, P. Koch, G. Koekoek, Y. Kojima, K. Kokeyama, S. Koley, P. Kolitsidou, M. Kolstein, K. Komori, V. Kondrashov, A. K. H. Kong, A. Kontos, N. Koper, M. Korobko, K. Kotake, M. Kovalam, D. B. Kozak, C. Kozakai, R. Kozu, V. Kringel, N. V. Krishnendu, A. Królak, G. Kuehn, F. Kuei, P. Kuijer, S. Kulkarni, A. Kumar, P. Kumar, Rahul Kumar, Rakesh Kumar, J. Kume, K. Kuns, C. Kuo, H-S. Kuo, Y. Kuromiya, S. Kuroyanagi, K. Kusayanagi, S. Kuwahara, K. Kwak, P. Lagabbe, D. Laghi, E. Lalande, T. L. Lam, A. Lamberts, M. Landry, B. B. Lane, R. N. Lang, J. Lange, B. Lantz, I. La Rosa, A. Lartaux-Vollard, P. D. Lasky, M. Laxen, A. Lazzarini, C. Lazzaro, P. Leaci, S. Leavey, Y. K. Lecoeuche, H. K. Lee, H. M. Lee, H. W. Lee, J. Lee, K. Lee, R. Lee, J. Lehmann, A. Lemaître, M. Leonardi, N. Leroy, N. Letendre, C. Levesque, Y. Levin, J. N. Leviton, K. Leyde, A. K. Y. Li, B. Li, J. Li, K. L. Li, T. G. F. Li, X. Li, C-Y. Lin, F-K. Lin, F-L. Lin, H. L. Lin, L. C.-C. Lin, F. Linde, S. D. Linker, J. N. Linley, T. B. Littenberg, G. C. Liu, J. Liu, K. Liu, X. Liu, F. Llamas, M. Llorens-Monteagudo, R. K. L. Lo, A. Lockwood, M. Loh, L. T. London, A. Longo, D. Lopez, M. Lopez Portilla, M. Lorenzini, V. Loriette, M. Lormand, G. Losurdo, T. P. Lott, J. D. Lough, C. O. Lousto, G. Lovelace, J. F. Lucaccioni, H. Lück, D. Lumaca, A. P. Lundgren, L.-W. Luo, J. E. Lynam, R. Macas, M. MacInnis, D. M. Macleod, I. A. O. MacMillan, A. Macquet, I. Magaña Hernandez, C. Magazzù, R. M. Magee, R. Maggiore, M. Magnozzi, S. Mahesh, E. Majorana, C. Makarem, I. Maksimovic, S. Maliakal, A. Malik, N. Man, V. Mandic, V. Mangano, J. L. Mango, G. L. Mansell, M. Manske, M. Mantovani, M. Mapelli, F. Marchesoni, M. Marchio, F. Marion, Z. Mark, S. Márka, Z. Márka, C. Markakis, A. S. Markosyan, A. Markowitz, E. Maros, A. Marquina, S. Marsat, F. Martelli, I. W. Martin, R. M. Martin, M. Martinez, V. A. Martinez, V. Martinez, K. Martinovic, D. V. Martynov, E. J. Marx, H. Masalehdan, K. Mason, E. Massera, A. Masserot, T. J. Massinger, M. Masso-Reid, S. Mastrogiovanni, A. Matas, M. Mateu-Lucena, F. Matichard, M. Matiushechkina, N. Mavalvala, J. J. McCann, R. McCarthy, D. E. McClelland, P. K. McClincy, S. McCormick, L. McCuller, G. I. McGhee, S. C. McGuire, C. McIsaac, J. McIver, T. McRae, S. T. McWilliams, D. Meacher, M. Mehmet, A. K. Mehta, Q. Meijer, A. Melatos, D. A. Melchor, G. Mendell, A. Menendez-Vazquez, C. S. Menoni, R. A. Mercer, L. Mereni, K. Merfeld, E. L. Merilh, J. D. Merritt, M. Merzougui, S. Meshkov, C. Messenger, C. Messick, P. M. Meyers, F. Meylahn, A. Mhaske, A. Miani, H. Miao, I. Michaloliakos, C. Michel, Y. Michimura, H. Middleton, L. Milano, A. L. Miller, A. Miller, B. Miller, M. Millhouse, J. C. Mills, E. Milotti, O. Minazzoli, Y. Minenkov, N. Mio, Ll. M. Mir, M. Miravet-Tenés, C. Mishra, T. Mishra, T. Mistry, S. Mitra, V. P. Mitrofanov, G. Mitselmakher, R. Mittleman, O. Miyakawa, A. Miyamoto, Y. Miyazaki, K. Miyo, S. Miyoki, Geoffrey Mo, L. M. Modafferi, E. Moguel, K. Mogushi, S. R. P. Mohapatra, S. R. Mohite, I. Molina, M. Molina-Ruiz, M. Mondin, M. Montani, C. J. Moore, D. Moraru, F. Morawski, A. More, C. Moreno, G. Moreno, Y. Mori, S. Morisaki, Y. Moriwaki, G. Morrás, B. Mours, C. M. Mow-Lowry, S. Mozzon, F. Muciaccia, Arunava Mukherjee, D. 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Zhu, A. B. Zimmerman, Y. Zlochower, M. E. Zucker, and J. Zweizig
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Physics ,QC1-999 - Abstract
The third Gravitational-Wave Transient Catalog (GWTC-3) describes signals detected with Advanced LIGO and Advanced Virgo up to the end of their third observing run. Updating the previous GWTC-2.1, we present candidate gravitational waves from compact binary coalescences during the second half of the third observing run (O3b) between 1 November 2019, 15∶00 Coordinated Universal Time (UTC) and 27 March 2020, 17∶00 UTC. There are 35 compact binary coalescence candidates identified by at least one of our search algorithms with a probability of astrophysical origin p_{astro}>0.5. Of these, 18 were previously reported as low-latency public alerts, and 17 are reported here for the first time. Based upon estimates for the component masses, our O3b candidates with p_{astro}>0.5 are consistent with gravitational-wave signals from binary black holes or neutron-star–black-hole binaries, and we identify none from binary neutron stars. However, from the gravitational-wave data alone, we are not able to measure matter effects that distinguish whether the binary components are neutron stars or black holes. The range of inferred component masses is similar to that found with previous catalogs, but the O3b candidates include the first confident observations of neutron-star–black-hole binaries. Including the 35 candidates from O3b in addition to those from GWTC-2.1, GWTC-3 contains 90 candidates found by our analysis with p_{astro}>0.5 across the first three observing runs. These observations of compact binary coalescences present an unprecedented view of the properties of black holes and neutron stars.
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- 2023
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4. Probabilistic teleportation of a quantum dot spin qubit
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Y. Kojima, T. Nakajima, A. Noiri, J. Yoneda, T. Otsuka, K. Takeda, S. Li, S. D. Bartlett, A. Ludwig, A. D. Wieck, and S. Tarucha
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Physics ,QC1-999 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
Abstract Electron spins in semiconductor quantum dots have been intensively studied for implementing quantum computation and high-fidelity single- and two-qubit operations have recently been achieved. Quantum teleportation is a three-qubit protocol exploiting quantum entanglement and it serves as an essential primitive for more sophisticated quantum algorithms. Here we demonstrate a scheme for quantum teleportation based on direct Bell measurement for a single-electron spin qubit in a triple quantum dot utilizing the Pauli exclusion principle to create and detect maximally entangled states. The single spin polarization is teleported from the input qubit to the output qubit. We find this fidelity is primarily limited by singlet–triplet mixing, which can be improved by optimizing the device parameters. Our results may be extended to quantum algorithms with a larger number of semiconductor spin qubits.
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- 2021
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5. Population of Merging Compact Binaries Inferred Using Gravitational Waves through GWTC-3
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Physics ,QC1-999 - Abstract
We report on the population properties of compact binary mergers inferred from gravitational-wave observations of these systems during the first three LIGO-Virgo observing runs. The Gravitational-Wave Transient Catalog 3 (GWTC-3) contains signals consistent with three classes of binary mergers: binary black hole, binary neutron star, and neutron star–black hole mergers. We infer the binary neutron star merger rate to be between 10 and 1700 Gpc^{−3} yr^{−1} and the neutron star–black hole merger rate to be between 7.8 and 140 Gpc^{−3} yr^{−1}, assuming a constant rate density in the comoving frame and taking the union of 90% credible intervals for methods used in this work. We infer the binary black hole merger rate, allowing for evolution with redshift, to be between 17.9 and 44 Gpc^{-3} yr^{-1} at a fiducial redshift (z=0.2). The rate of binary black hole mergers is observed to increase with redshift at a rate proportional to (1+z)^{κ} with κ=2.9_{-1.8}^{+1.7} for z≲1. Using both binary neutron star and neutron star–black hole binaries, we obtain a broad, relatively flat neutron star mass distribution extending from 1.2_{-0.2}^{+0.1} to 2.0_{-0.3}^{+0.3}M_{⊙}. We confidently determine that the merger rate as a function of mass sharply declines after the expected maximum neutron star mass, but cannot yet confirm or rule out the existence of a lower mass gap between neutron stars and black holes. We also find the binary black hole mass distribution has localized over- and underdensities relative to a power-law distribution, with peaks emerging at chirp masses of 8.3_{-0.5}^{+0.3} and 27.9_{-1.8}^{+1.9}M_{⊙}. While we continue to find that the mass distribution of a binary’s more massive component strongly decreases as a function of primary mass, we observe no evidence of a strongly suppressed merger rate above approximately 60M_{⊙}, which would indicate the presence of a upper mass gap. Observed black hole spins are small, with half of spin magnitudes below χ_{i}≈0.25. While the majority of spins are preferentially aligned with the orbital angular momentum, we infer evidence of antialigned spins among the binary population. We observe an increase in spin magnitude for systems with more unequal-mass ratio. We also observe evidence of misalignment of spins relative to the orbital angular momentum.
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- 2023
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6. Search for Gravitational Waves Associated with Fast Radio Bursts Detected by CHIME/FRB during the LIGO–Virgo Observing Run O3a
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Zwaniga, The LIGO Scientific Collaboration, The Virgo Collaboration, The KAGRA Collaboration, and The CHIME/FRB Collaboration
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Gravitational wave astronomy ,Radio transient sources ,Astrophysics ,QB460-466 - Abstract
We search for gravitational-wave (GW) transients associated with fast radio bursts (FRBs) detected by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst Project, during the first part of the third observing run of Advanced LIGO and Advanced Virgo (2019 April 1 15:00 UTC–2019 October 1 15:00 UTC). Triggers from 22 FRBs were analyzed with a search that targets both binary neutron star (BNS) and neutron star–black hole (NSBH) mergers. A targeted search for generic GW transients was conducted on 40 FRBs. We find no significant evidence for a GW association in either search. Given the large uncertainties in the distances of our FRB sample, we are unable to exclude the possibility of a GW association. Assessing the volumetric event rates of both FRB and binary mergers, an association is limited to 15% of the FRB population for BNS mergers or 1% for NSBH mergers. We report 90% confidence lower bounds on the distance to each FRB for a range of GW progenitor models and set upper limits on the energy emitted through GWs for a range of emission scenarios. We find values of order 10 ^51 –10 ^57 erg for models with central GW frequencies in the range 70–3560 Hz. At the sensitivity of this search, we find these limits to be above the predicted GW emissions for the models considered. We also find no significant coincident detection of GWs with the repeater, FRB 20200120E, which is the closest known extragalactic FRB.
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- 2023
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7. Thermal desorption processes of H2 and CH4 from Li2ZrO3 and Li4SiO4 materials absorbed H2O and CO2 in air at room temperature
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B. Tsuchiya, T. Kodera, H. Miyaoka, T. Ichikawa, and Y. Kojima
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Fuel Technology ,Renewable Energy, Sustainability and the Environment ,Energy Engineering and Power Technology ,Condensed Matter Physics - Published
- 2023
8. Observation of Gravitational Waves from Two Neutron Star–Black Hole Coalescences
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Zhang, J. Zhang, L. Zhang, R. Zhang, T. Zhang, C. Zhao, G. Zhao, Yue Zhao, Yuhang Zhao, Z. Zhou, X. J. Zhu, Z.-H. Zhu, A. B. Zimmerman, Y. Zlochower, M. E. Zucker, J. Zweizig, and the LIGO Scientific Collaboration, the Virgo Collaboration, and the KAGRA Collaboration
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Astrophysics ,QB460-466 - Abstract
We report the observation of gravitational waves from two compact binary coalescences in LIGO’s and Virgo’s third observing run with properties consistent with neutron star–black hole (NSBH) binaries. The two events are named GW200105_162426 and GW200115_042309, abbreviated as GW200105 and GW200115; the first was observed by LIGO Livingston and Virgo and the second by all three LIGO–Virgo detectors. The source of GW200105 has component masses $8.{9}_{-1.5}^{+1.2}$ and $1.{9}_{-0.2}^{+0.3}\,{M}_{\odot }$ , whereas the source of GW200115 has component masses $5.{7}_{-2.1}^{+1.8}$ and $1.{5}_{-0.3}^{+0.7}\,{M}_{\odot }$ (all measurements quoted at the 90% credible level). The probability that the secondary’s mass is below the maximal mass of a neutron star is 89%–96% and 87%–98%, respectively, for GW200105 and GW200115, with the ranges arising from different astrophysical assumptions. The source luminosity distances are ${280}_{-110}^{+110}$ and ${300}_{-100}^{+150}\,\mathrm{Mpc}$ , respectively. The magnitude of the primary spin of GW200105 is less than 0.23 at the 90% credible level, and its orientation is unconstrained. For GW200115, the primary spin has a negative spin projection onto the orbital angular momentum at 88% probability. We are unable to constrain the spin or tidal deformation of the secondary component for either event. We infer an NSBH merger rate density of ${45}_{-33}^{+75}\,{\mathrm{Gpc}}^{-3}\,{\mathrm{yr}}^{-1}$ when assuming that GW200105 and GW200115 are representative of the NSBH population or ${130}_{-69}^{+112}\,{\mathrm{Gpc}}^{-3}\,{\mathrm{yr}}^{-1}$ under the assumption of a broader distribution of component masses.
- Published
- 2021
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9. Narrowband Searches for Continuous and Long-duration Transient Gravitational Waves from Known Pulsars in the LIGO-Virgo Third Observing Run
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W. Stappers, C. M. Tan, G. Theureau, and P. Weltevrede
- Subjects
Gravitational wave astronomy ,Neutron stars ,Pulsars ,Astrophysics ,QB460-466 - Abstract
Isolated neutron stars that are asymmetric with respect to their spin axis are possible sources of detectable continuous gravitational waves. This paper presents a fully coherent search for such signals from eighteen pulsars in data from LIGO and Virgo’s third observing run (O3). For known pulsars, efficient and sensitive matched-filter searches can be carried out if one assumes the gravitational radiation is phase-locked to the electromagnetic emission. In the search presented here, we relax this assumption and allow both the frequency and the time derivative of the frequency of the gravitational waves to vary in a small range around those inferred from electromagnetic observations. We find no evidence for continuous gravitational waves, and set upper limits on the strain amplitude for each target. These limits are more constraining for seven of the targets than the spin-down limit defined by ascribing all rotational energy loss to gravitational radiation. In an additional search, we look in O3 data for long-duration (hours–months) transient gravitational waves in the aftermath of pulsar glitches for six targets with a total of nine glitches. We report two marginal outliers from this search, but find no clear evidence for such emission either. The resulting duration-dependent strain upper limits do not surpass indirect energy constraints for any of these targets.
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- 2022
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10. A fast quantum interface between different spin qubit encodings
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A. Noiri, T. Nakajima, J. Yoneda, M. R. Delbecq, P. Stano, T. Otsuka, K. Takeda, S. Amaha, G. Allison, K. Kawasaki, Y. Kojima, A. Ludwig, A. D. Wieck, D. Loss, and S. Tarucha
- Subjects
Science - Abstract
The race to produce a quantum computer has driven the development of many different qubit designs with different benefits and drawbacks. Noiri et al. demonstrate a hybrid device with two coupled semiconductor spin qubits of different designs, which should allow each qubit’s advantages to be exploited.
- Published
- 2018
- Full Text
- View/download PDF
11. Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA
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Miao, C. Michel, Y. Michimura, H. Middleton, E. E. Mikhailov, L. Milano, A. L. Miller, A. Miller, B. B. Miller, J. Miller, M. Millhouse, Y. Minenkov, J. Ming, S. Mirshekari, C. Mishra, V. P. Mitrofanov, G. Mitselmakher, R. Mittleman, O. Miyakawa, A. Miyamoto, T. Miyamoto, S. Miyoki, A. Moggi, M. Mohan, S. R. P. Mohapatra, M. Montani, B. C. Moore, C. J. Moore, D. Moraru, G. Moreno, W. Morii, S. Morisaki, Y. Moriwaki, S. R. Morriss, B. Mours, C. M. Mow-Lowry, G. Mueller, A. W. Muir, Arunava Mukherjee, D. Mukherjee, S. Mukherjee, N. Mukund, A. Mullavey, J. Munch, E. A. M. Muniz, P. G. Murray, A. Mytidis, S. Nagano, K. Nakamura, T. Nakamura, H. Nakano, Masaya Nakano, Masayuki Nakano, K. Nakao, K. Napier, I. Nardecchia, T. Narikawa, L. Naticchioni, G. Nelemans, T. J. N. Nelson, M. Neri, M. Nery, A. Neunzert, J. M. Newport, G. Newton, T. T. Nguyen, W.-T. Ni, A. B. Nielsen, S. Nissanke, A. Nitz, A. Noack, F. Nocera, D. Nolting, M. E. N. Normandin, L. K. Nuttall, J. Oberling, E. Ochsner, E. Oelker, G. H. Ogin, J. J. Oh, S. H. Oh, M. Ohashi, N. Ohishi, M. Ohkawa, F. Ohme, K. Okutomi, M. Oliver, K. Ono, Y. Ono, K. Oohara, P. Oppermann, Richard J. Oram, B. O’Reilly, R. O’Shaughnessy, D. J. Ottaway, H. Overmier, B. J. Owen, A. E. Pace, J. Page, A. Pai, S. A. Pai, J. R. Palamos, O. Palashov, C. Palomba, A. Pal-Singh, H. Pan, C. Pankow, F. Pannarale, B. C. Pant, F. Paoletti, A. Paoli, M. A. Papa, H. R. Paris, W. Parker, D. Pascucci, A. Pasqualetti, R. Passaquieti, D. Passuello, B. Patricelli, B. L. Pearlstone, M. Pedraza, R. Pedurand, L. Pekowsky, A. Pele, F. E. Peña Arellano, S. Penn, C. J. Perez, A. Perreca, L. M. Perri, H. P. Pfeiffer, M. Phelps, O. J. Piccinni, M. Pichot, F. Piergiovanni, V. Pierro, G. Pillant, L. Pinard, I. M. Pinto, M. Pitkin, M. Poe, R. Poggiani, P. Popolizio, A. Post, J. Powell, J. Prasad, J. W. W. Pratt, V. Predoi, T. Prestegard, M. Prijatelj, M. Principe, S. Privitera, G. A. Prodi, L. G. Prokhorov, O. Puncken, M. Punturo, P. Puppo, M. Pürrer, H. Qi, J. Qin, S. Qiu, V. Quetschke, E. A. Quintero, R. Quitzow-James, F. J. Raab, D. S. Rabeling, H. Radkins, P. Raffai, S. Raja, C. Rajan, M. Rakhmanov, P. Rapagnani, V. Raymond, M. Razzano, V. Re, J. Read, T. Regimbau, L. Rei, S. Reid, D. H. Reitze, H. Rew, S. D. Reyes, E. Rhoades, F. Ricci, K. Riles, M. Rizzo, N. A. Robertson, R. Robie, F. Robinet, A. Rocchi, L. Rolland, J. G. Rollins, V. J. Roma, R. Romano, J. H. Romie, D. Rosińska, S. Rowan, A. Rüdiger, P. Ruggi, K. Ryan, S. Sachdev, T. Sadecki, L. Sadeghian, N. Sago, M. Saijo, Y. Saito, K. Sakai, M. Sakellariadou, L. Salconi, M. Saleem, F. Salemi, A. Samajdar, L. Sammut, L. M. Sampson, E. J. Sanchez, V. Sandberg, J. R. Sanders, Y. Sasaki, B. Sassolas, B. S. Sathyaprakash, S. Sato, T. Sato, P. R. Saulson, O. Sauter, R. L. Savage, A. Sawadsky, P. Schale, J. Scheuer, E. Schmidt, J. Schmidt, P. Schmidt, R. Schnabel, R. M. S. Schofield, A. Schönbeck, E. Schreiber, D. Schuette, B. F. Schutz, S. G. Schwalbe, J. Scott, S. M. Scott, T. Sekiguchi, Y. Sekiguchi, D. Sellers, A. S. Sengupta, D. Sentenac, V. Sequino, A. Sergeev, Y. Setyawati, D. A. Shaddock, T. J. Shaffer, M. S. Shahriar, B. Shapiro, P. Shawhan, A. Sheperd, M. Shibata, Y. Shikano, T. Shimoda, A. Shoda, D. H. Shoemaker, D. M. Shoemaker, K. Siellez, X. Siemens, M. Sieniawska, D. Sigg, A. D. Silva, A. Singer, L. P. Singer, A. Singh, R. Singh, A. Singhal, A. M. Sintes, B. J. J. Slagmolen, B. Smith, J. R. Smith, R. J. E. Smith, K. Somiya, E. J. Son, B. Sorazu, F. Sorrentino, T. Souradeep, A. P. Spencer, A. K. Srivastava, A. Staley, M. Steinke, J. Steinlechner, S. Steinlechner, D. Steinmeyer, B. C. Stephens, S. P. Stevenson, R. Stone, K. A. Strain, N. Straniero, G. Stratta, S. E. Strigin, R. Sturani, A. L. Stuver, Y. Sugimoto, T. Z. Summerscales, L. Sun, S. Sunil, P. J. Sutton, T. Suzuki, B. L. Swinkels, M. J. Szczepańczyk, M. Tacca, H. Tagoshi, S. Takada, H. Takahashi, R. Takahashi, A. Takamori, D. Talukder, H. Tanaka, K. Tanaka, T. Tanaka, D. B. Tanner, M. Tápai, A. Taracchini, D. Tatsumi, R. Taylor, S. Telada, T. Theeg, E. G. Thomas, M. Thomas, P. Thomas, K. A. Thorne, E. Thrane, T. Tippens, S. Tiwari, V. Tiwari, K. V. Tokmakov, K. Toland, T. Tomaru, C. Tomlinson, M. Tonelli, Z. Tornasi, C. I. Torrie, D. Töyrä, F. Travasso, G. Traylor, D. Trifirò, J. Trinastic, M. C. Tringali, L. Trozzo, M. Tse, R. Tso, K. Tsubono, T. Tsuzuki, M. Turconi, D. Tuyenbayev, T. Uchiyama, T. Uehara, S. Ueki, K. Ueno, D. Ugolini, C. S. Unnikrishnan, A. L. Urban, T. Ushiba, S. A. Usman, H. Vahlbruch, G. Vajente, G. Valdes, N. van Bakel, M. van Beuzekom, J. F. J. van den Brand, C. Van Den Broeck, D. C. Vander-Hyde, L. van der Schaaf, J. V. van Heijningen, M. H. P. M. van Putten, A. A. van Veggel, M. Vardaro, V. Varma, S. Vass, M. Vasúth, A. Vecchio, G. Vedovato, J. Veitch, P. J. Veitch, K. Venkateswara, G. Venugopalan, D. Verkindt, F. Vetrano, A. Viceré, A. D. Viets, S. Vinciguerra, D. J. Vine, J.-Y. Vinet, S. Vitale, T. Vo, H. Vocca, C. Vorvick, D. V. Voss, W. D. Vousden, S. P. Vyatchanin, A. R. Wade, L. E. Wade, M. Wade, T. Wakamatsu, M. Walker, L. Wallace, S. Walsh, G. Wang, H. Wang, M. Wang, Y. Wang, R. L. Ward, J. Warner, M. Was, J. Watchi, B. Weaver, L.-W. Wei, M. Weinert, A. J. Weinstein, R. Weiss, L. Wen, P. Weßels, T. Westphal, K. Wette, J. T. Whelan, B. F. Whiting, C. Whittle, D. Williams, R. D. Williams, A. R. Williamson, J. L. Willis, B. Willke, M. H. Wimmer, W. Winkler, C. C. Wipf, H. Wittel, G. Woan, J. Woehler, J. Worden, J. L. Wright, D. S. Wu, G. Wu, W. Yam, H. Yamamoto, K. Yamamoto, T. Yamamoto, C. C. Yancey, K. Yano, M. J. Yap, J. Yokoyama, T. Yokozawa, T. H. Yoon, Hang Yu, Haocun Yu, H. Yuzurihara, M. Yvert, A. Zadrożny, L. Zangrando, M. Zanolin, S. Zeidler, J.-P. Zendri, M. Zevin, L. Zhang, M. Zhang, T. Zhang, Y. Zhang, C. Zhao, M. Zhou, Z. Zhou, S. J. Zhu, X. J. Zhu, M. E. Zucker, J. Zweizig, and KAGRA Collaboration, LIGO Scientific Collaboration and Virgo Collaboration
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Gravitational waves ,Gravitational-wave detectors ,Electromagnetic counterparts ,Data analysis ,Atomic physics. Constitution and properties of matter ,QC170-197 - Abstract
Abstract We present possible observing scenarios for the Advanced LIGO, Advanced Virgo and KAGRA gravitational-wave detectors over the next decade, with the intention of providing information to the astronomy community to facilitate planning for multi-messenger astronomy with gravitational waves. We estimate the sensitivity of the network to transient gravitational-wave signals, and study the capability of the network to determine the sky location of the source. We report our findings for gravitational-wave transients, with particular focus on gravitational-wave signals from the inspiral of binary neutron star systems, which are the most promising targets for multi-messenger astronomy. The ability to localize the sources of the detected signals depends on the geographical distribution of the detectors and their relative sensitivity, and $$90\%$$ 90% credible regions can be as large as thousands of square degrees when only two sensitive detectors are operational. Determining the sky position of a significant fraction of detected signals to areas of 5–$$20~\mathrm {deg}^2$$ 20deg2 requires at least three detectors of sensitivity within a factor of $$\sim 2$$ ∼2 of each other and with a broad frequency bandwidth. When all detectors, including KAGRA and the third LIGO detector in India, reach design sensitivity, a significant fraction of gravitational-wave signals will be localized to a few square degrees by gravitational-wave observations alone.
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- 2018
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12. Rapid Determination of Fatigue Limit Using Temperature Second Harmonic
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A. Akai, Y. Sato, M. Murase, Y. Kojima, and Y. Okubo
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Mechanics of Materials ,Mechanical Engineering ,Aerospace Engineering - Published
- 2022
13. Characteristic endoscopic findings of gastrointestinal malignant lymphomas other than mucosa-associated lymphoid tissue lymphoma
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T, Kanno, T, Katano, T, Shimura, R, Nishigaki, Y, Kojima, M, Sasaki, Y, Okuda, N, Sugimura, S, Fukusada, Y, Mizuno, H, Iwasaki, H, Nishie, M, Tanaka, K, Ozeki, E, Kubota, S, Tanida, and H, Kataoka
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Humans ,Lymphoma, B-Cell, Marginal Zone ,Lymphoma, Large B-Cell, Diffuse ,Ulcer ,Gastrointestinal Neoplasms ,Retrospective Studies - Abstract
Background and study aims: The gastrointestinal (GI) tract is the most common site of extra-nodal involvement for non-Hodgkin’s lymphoma (NHL). The features of GI NHLs remain unclear. The aim of this study was to clarify endoscopic characteristics of GI NHLs. Patients and methods: We retrospectively analyzed the morphological characteristics of 63 GI malignant lymphomas other than mucosa-associated lymphoid tissue lymphoma. Lesions were diagnosed between 2005 and 2020. Macroscopic findings were classified into five subtypes: superficial (S); protruding without ulcer (P); protruding with ulcer (PU); fungating (F); and multiple nodules (MN). Results: Thirty-one lesions in the stomach were classified as S type in 3 cases (9.6%), P type in 6 (19%), PU type in 13 (42%), and F type in 9 (29%). In the stomach, the ulcerated phenotype was more frequent for diffuse large B-cell lymphoma (DLBCL) (89.5%) than for other histological types (41.7%; P = 0.01). In the intestine, 23 tumors were classified as S type in 4 cases (17%), P type in 1 (4%), PU type in 6 (26%), F type in 1 (4%), and MN in 11 (48%). Eleven of the 14 cases (78.6%) of intestinal follicular lymphoma lesions showed MN type. In the colon, eight tumors were classified as S type in 2 cases (25%), P type in 2 (25%), PU type in 1 (13%), and F type in 3 (38%). Conclusion: We have clarified the endoscopic features of GI NHL using macroscopic classifications. The ulcerated phenotype was the most frequent endoscopic finding for DLBCL.
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- 2022
14. Efficient Random Number for the Masking Method against DPA Attacks.
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Masaya Yoshikawa and Y. Kojima
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- 2011
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15. Diffuse Liver Metastasis of Small-Cell Lung Cancer Presenting as Acute Liver Failure and Diagnosed by Transjugular Liver Biopsy: A Rare Case in Whom Nodular Lesions Were Detected by Enhanced CT Examination
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S. Mishima, Y. Nozaki, S. Mikami, E. Kihira, M. Iikura, R. Koketsu, H. Sugiyama, T. Masuda, H. Kaname, Y. Egami, T. Nakayama, K. Hasuo, H. Nakamura, T. Igari, K. Watanabe, N. Nagata, T. Sakurai, C. Yokoi, M. Kobayakawa, Y. Kojima, J. Akiyama, M. Imamura, N. Masaki, and M. Yanase
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Small-cell lung cancer ,Diffuse liver metastasis ,Acute liver failure ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Small-cell lung cancer (SCLC) is a subgroup of lung cancer with a high frequency of liver metastasis, which is a predictor of poor prognosis. Diffuse liver metastases of SCLC with no visible nodular lesions in the liver when examined using computed tomography (CT) are relatively rare; however, a few cases with rapid progression to acute liver failure that were diagnosed after death have been reported. In this paper, we report a 63-year-old man with diffuse liver metastases of SCLC that were histologically diagnosed using a transjugular liver biopsy while the patient was alive, even though no lesions were visible during a contrast-enhanced CT examination.
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- 2015
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16. Neointimal vulnerability on optical coherence tomography and slow flow during percutaneous coronary intervention of healed neointima
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H Amano, Y Kojima, S Hirano, Y Oka, H Aikawa, S Matsumoto, R Noike, T Yabe, R Okubo, and T Ikeda
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Cardiology and Cardiovascular Medicine - Abstract
Backgrounds Healed plaques in native coronary artery indicate the repair phenomenon of ruptured fibrous caps and erosions [1, 2, 3]. Healed plaques associated with plaque vulnerability [4]. A similar phenomenon is considered to occur in neointima after stent implantation [5]. However, there are few reports in the literature regarding neointimal vulnerability and procedure outcomes of healed tissue in neointima. Objective The aims of this study are to investigate clinical characteristics, slow flow during percutaneous coronary intervention (PCI), and neointimal vulnerability of healed neointima by optical coherence tomography (OCT). Methods We treated 67 lesions by PCI for in-stent restenosis (ISR) and conducted OCT examinations. Healed neointima was defined as neointima having one or more layers with different optical densities and a clear demarcation from underlying components. ISR with healed neointima was found in 49% (33/67) of the lesions. The angiographic slow flow was defined as a decrease of at least 1 grade in TIMI flow during PCI or final TIMI flow grade 0 and 1 or 2, with no evidence of thrombus, spasm, or dissection. Stents with a strut thickness ≥100 μm were classified as thick [6]. Results Compared to ISR without healed neointima, ISR with healed neointima showed significantly longer stent age (102±72 months vs. 31±39 months, p Conclusions ISR with healed neointima was associated with neointimal vulnerability, stent age, stent type, stent strut thickness, stent expansion, antiplatelet therapy, HDL-C and triglycerides levels, and use of ACE-I or ARB. There were no relations between with healed neointima and slow flow during PCI. Funding Acknowledgement Type of funding sources: None.
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- 2022
17. RRAP: RPKM Recruitment Analysis Pipeline
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Conner Y. Kojima, Eric W. Getz, and J. Cameron Thrash
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Immunology and Microbiology (miscellaneous) ,Genetics ,Molecular Biology - Abstract
A common method for quantifying microbial abundances in situ is through metagenomic read recruitment to genomes and normalizing read counts as reads per kilobase (of genome) per million (bases of recruited sequences) (RPKM). We created RRAP (RPKM Recruitment Analysis Pipeline), a wrapper that automates this process using Bowtie2 and SAMtools.
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- 2022
18. Ecophysiology and genomics of the brackish water adapted SAR11 subclade IIIa
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V. Celeste Lanclos, Anna N. Rasmussen, Conner Y. Kojima, Chuankai Cheng, Michael W. Henson, Brant C. Faircloth, Christopher A. Francis, and J. Cameron Thrash
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Microbiology ,Ecology, Evolution, Behavior and Systematics - Abstract
The Order Pelagibacterales (SAR11) is the most abundant group of heterotrophic bacterioplankton in global oceans and comprises multiple subclades with unique spatiotemporal distributions. Subclade IIIa is the primary SAR11 group in brackish waters and shares a common ancestor with the dominant freshwater IIIb (LD12) subclade. Despite its dominance in brackish environments, subclade IIIa lacks systematic genomic or ecological studies. Here, we combine closed genomes from new IIIa isolates, new IIIa MAGS from San Francisco Bay (SFB), and 460 highly complete publicly available SAR11 genomes for the most comprehensive pangenomic study of subclade IIIa to date. Subclade IIIa represents a taxonomic family containing three genera (denoted as subgroups IIIa.1, IIIa.2, and IIIa.3) that had distinct ecological distributions related to salinity. The expansion of taxon selection within subclade IIIa also established previously noted metabolic differentiation in subclade IIIa compared to other SAR11 subclades such as glycine/serine prototrophy, mosaic glyoxylate shunt presence, and polyhydroxyalkanoate synthesis potential. Our analysis further shows metabolic flexibility among subgroups within IIIa. Additionally, we find that subclade IIIa.3 bridges the marine and freshwater clades based on its potential for compatible solute transport, iron utilization, and bicarbonate management potential. Pure culture experimentation validated differential salinity ranges in IIIa.1 and IIIa.3 and provided detailed IIIa cell size and volume data. This study is an important step forward for understanding the genomic, ecological, and physiological differentiation of subclade IIIa and the overall evolutionary history of SAR11.
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- 2022
19. Design standard for railway shotcrete tunnels in urban area in Japan
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S. Konishi, Y. Kojima, Y. Arai, K. Tsuno, Y. Kawashima, and T. Asakura
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- 2022
20. Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift during the LIGO-Virgo Run O3b
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Abbott, R, Abbott, T, Acernese, F, Ackley, K, Adams, C, Adhikari, N, Adhikari, R, Adya, V, Affeldt, C, Agarwal, D, Agathos, M, Agatsuma, K, Aggarwal, N, Aguiar, O, Aiello, L, Ain, A, Ajith, P, Akutsu, T, Albanesi, S, Allocca, A, Altin, P, Amato, A, Anand, C, Anand, S, Ananyeva, A, Anderson, S, Anderson, W, Ando, M, Andrade, T, Andres, N, Andri??, T, Angelova, S, Ansoldi, S, Antelis, J, Antier, S, Appert, S, Arai, K, Arai, Y, Araki, S, Araya, A, Araya, M, Areeda, J, Ar??ne, M, Aritomi, N, Arnaud, N, Aronson, S, Arun, K, Asada, H, Asali, Y, Ashton, G, Aso, Y, Assiduo, M, Aston, S, Astone, P, Aubin, F, Austin, C, Babak, S, Badaracco, F, Bader, M, Badger, C, Bae, S, Bae, Y, Baer, A, Bagnasco, S, Bai, Y, Baiotti, L, Baird, J, Bajpai, R, Ball, M, Ballardin, G, Ballmer, S, Balsamo, A, Baltus, G, Banagiri, S, Bankar, D, Barayoga, J, Barbieri, C, Barish, B, Barker, D, Barneo, P, Barone, F, Barr, B, Barsotti, L, Barsuglia, M, Barta, D, Bartlett, J, Barton, M, Bartos, I, Bassiri, R, Basti, A, Bawaj, M, Bayley, J, Baylor, A, Bazzan, M, B??csy, B, Bedakihale, V, Bejger, M, Belahcene, I, Benedetto, V, Beniwal, D, Bennett, T, Bentley, J, Benyaala, M, Bergamin, F, Berger, B, Bernuzzi, S, Berry, C, Bersanetti, D, Bertolini, A, Betzwieser, J, Beveridge, D, Bhandare, R, Bhardwaj, U, Bhattacharjee, D, Bhaumik, S, Bilenko, I, Billingsley, G, Bini, S, Birney, R, Birnholtz, O, Biscans, S, Bischi, M, Biscoveanu, S, Bisht, A, Biswas, B, Bitossi, M, Bizouard, M, Blackburn, J, Blair, C, Blair, D, Blair, R, Bobba, F, Bode, N, Boer, M, Bogaert, G, Boldrini, M, Bonavena, L, Bondu, F, Bonilla, E, Bonnand, R, Booker, P, Boom, B, Bork, R, Boschi, V, Bose, N, Bose, S, Bossilkov, V, Boudart, V, Bouffanais, Y, Bozzi, A, Bradaschia, C, Brady, P, Bramley, A, Branch, A, Branchesi, M, Brau, J, Breschi, M, Briant, T, Briggs, J, Brillet, A, Brinkmann, M, Brockill, P, Brooks, A, Brooks, J, Brown, D, Brunett, S, Bruno, G, Bruntz, R, Bryant, J, Bulik, T, Bulten, H, Buonanno, A, Buscicchio, R, Buskulic, D, Buy, C, Byer, R, Cadonati, L, Cagnoli, G, Cahillane, C, Bustillo, J, Callaghan, J, Callister, T, Calloni, E, Cameron, J, Camp, J, Canepa, M, Canevarolo, S, Cannavacciuolo, M, Cannon, K, Cao, H, Cao, Z, Capocasa, E, Capote, E, Carapella, G, Carbognani, F, Carlin, J, Carney, M, Carpinelli, M, Carrillo, G, Carullo, G, Carver, T, Casanueva Diaz, J, Casentini, C, Castaldi, G, Caudill, S, Cavagli??, M, Cavalier, F, Cavalieri, R, Ceasar, M, Cella, G, Cerd??-Dur??n, P, Cesarini, E, Chaibi, W, Chakravarti, K, Chalathadka Subrahmanya, S, Champion, E, Chan, C, Chan, K, Chan, M, Chandra, K, Chanial, P, Chao, S, Charlton, P, Chase, E, Chassande-Mottin, E, Chatterjee, C, Chatterjee, D, Chaturvedi, M, Chaty, S, Chatziioannou, K, Chen, C, Chen, H, Chen, J, Chen, K, Chen, X, Chen, Y, Chen, Z, Cheng, H, Cheong, C, Cheung, H, Chia, H, Chiadini, F, Chiang, C, Chiarini, G, Chierici, R, Chincarini, A, Chiofalo, M, Chiummo, A, Cho, G, Cho, H, Choudhary, R, Choudhary, S, Christensen, N, Chu, H, Chu, Q, Chu, Y, Chua, S, Chung, K, Ciani, G, Ciecielag, P, Cie??lar, M, Cifaldi, M, Ciobanu, A, Ciolfi, R, Cipriano, F, Cirone, A, Clara, F, Clark, E, Clark, J, Clarke, L, Clearwater, P, Clesse, S, Cleva, F, Coccia, E, Codazzo, E, Cohadon, P, Cohen, D, Cohen, L, Colleoni, M, Collette, C, Colombo, A, Colpi, M, Compton, C, Constancio, M, Conti, L, Cooper, S, Corban, P, Corbitt, T, Cordero-Carri??n, I, Corezzi, S, Corley, K, Cornish, N, Corre, D, Corsi, A, Cortese, S, Costa, C, Cotesta, R, Coughlin, M, Coulon, J, Countryman, S, Cousins, B, Couvares, P, Coward, D, Cowart, M, Coyne, D, Coyne, R, Creighton, J, Creighton, T, Criswell, A, Croquette, M, Crowder, S, Cudell, J, Cullen, T, Cumming, A, Cummings, R, Cunningham, L, Cuoco, E, Cury??o, M, Dabadie, P, Dal Canton, T, Dall???osso, S, D??lya, G, Dana, A, Daneshgaranbajastani, L, D???angelo, B, Danilishin, S, D???antonio, S, Danzmann, K, Darsow-Fromm, C, Dasgupta, A, Datrier, L, Datta, S, Dattilo, V, Dave, I, Davier, M, Davies, G, Davis, D, Davis, M, Daw, E, Dean, R, Debra, D, Deenadayalan, M, Degallaix, J, De Laurentis, M, Del??glise, S, Del Favero, V, De Lillo, F, De Lillo, N, Del Pozzo, W, Demarchi, L, De Matteis, F, D???emilio, V, Demos, N, Dent, T, Depasse, A, De Pietri, R, De Rosa, R, De Rossi, C, Desalvo, R, De Simone, R, Dhurandhar, S, D??az, M, Diaz-Ortiz, M, Didio, N, Dietrich, T, Di Fiore, L, Di Fronzo, C, Di Giorgio, C, Di Giovanni, F, Di Giovanni, M, Di Girolamo, T, Di Lieto, A, Ding, B, Di Pace, S, Di Palma, I, Di Renzo, F, Divakarla, A, Dmitriev, A, Doctor, Z, D???onofrio, L, Donovan, F, Dooley, K, Doravari, S, Dorrington, I, Drago, M, Driggers, J, Drori, Y, Ducoin, J, Dupej, P, Durante, O, D???urso, D, Duverne, P, Dwyer, S, Eassa, C, Easter, P, Ebersold, M, Eckhardt, T, Eddolls, G, Edelman, B, Edo, T, Edy, O, Effler, A, Eguchi, S, Eichholz, J, Eikenberry, S, Eisenmann, M, Eisenstein, R, Ejlli, A, Engelby, E, Enomoto, Y, Errico, L, Essick, R, Estell??s, H, Estevez, D, Etienne, Z, Etzel, T, Evans, M, Evans, T, Ewing, 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Guidi, A. R. Guimaraes, G. Guix??, H. K. Gulati, H. -K. Guo, Y. Guo, Anchal Gupta, Anuradha Gupta, P. Gupta, E. K. Gustafson, R. Gustafson, F. Guzman, S. Ha, L. Haegel, A. Hagiwara, S. Haino, O. Halim, E. D. Hall, E. Z. Hamilton, G. Hammond, W. -B. Han, M. Haney, J. Hanks, C. Hanna, M. D. Hannam, O. Hannuksela, H. Hansen, T. J. Hansen, J. Hanson, T. Harder, T. Hardwick, K. Haris, J. Harms, G. M. Harry, I. W. Harry, D. Hartwig, K. Hasegawa, B. Haskell, R. K. Hasskew, C. -J. Haster, K. Hattori, K. Haughian, H. Hayakawa, K. Hayama, F. J. Hayes, J. Healy, A. Heidmann, A. Heidt, M. C. Heintze, J. Heinze, J. Heinzel, H. Heitmann, F. Hellman, P. Hello, A. F. Helmling-Cornell, G. Hemming, M. Hendry, I. S. Heng, E. Hennes, J. Hennig, M. H. Hennig, A. G. Hernandez, F. Hernandez Vivanco, M. Heurs, S. Higginbotham, S. Hild, P. Hill, Y. Himemoto, A. S. Hines, Y. Hiranuma, N. Hirata, E. Hirose, S. Hochheim, D. Hofman, J. N. Hohmann, D. G. Holcomb, N. A. Holland, I. J. Hollows, Z. J. Holmes, K. Holt, D. E. Holz, Z. Hong, P. Hopkins, J. Hough, S. Hourihane, E. J. Howell, C. G. Hoy, D. Hoyland, A. Hreibi, B-H. Hsieh, Y. Hsu, G-Z. Huang, H-Y. Huang, P. Huang, Y-C. Huang, Y. -J. Huang, Y. Huang, M. T. H??bner, A. D. Huddart, B. Hughey, D. C. Y. Hui, V. Hui, S. Husa, S. H. Huttner, R. Huxford, T. Huynh-Dinh, S. Ide, B. Idzkowski, A. Iess, B. Ikenoue, S. Imam, K. Inayoshi, C. Ingram, Y. Inoue, K. Ioka, M. Isi, K. Isleif, K. Ito, Y. Itoh, B. R. Iyer, K. Izumi, V. JaberianHamedan, T. Jacqmin, S. J. Jadhav, S. P. Jadhav, A. L. James, A. Z. Jan, K. Jani, J. Janquart, K. Janssens, N. N. Janthalur, P. Jaranowski, D. Jariwala, R. Jaume, A. C. Jenkins, K. Jenner, C. Jeon, M. Jeunon, W. Jia, H. -B. Jin, G. R. Johns, A. W. Jones, D. I. Jones, J. D. Jones, P. Jones, R. Jones, R. J. G. Jonker, L. Ju, P. Jung, K. Jung, J. Junker, V. Juste, K. Kaihotsu, T. Kajita, M. Kakizaki, C. V. Kalaghatgi, V. Kalogera, B. Kamai, M. Kamiizumi, N. Kanda, S. Kandhasamy, G. Kang, J. B. Kanner, Y. Kao, S. J. Kapadia, D. P. Kapasi, S. Karat, C. Karathanasis, S. Karki, R. Kashyap, M. Kasprzack, W. Kastaun, S. Katsanevas, E. Katsavounidis, W. Katzman, T. Kaur, K. Kawabe, K. Kawaguchi, N. Kawai, T. Kawasaki, F. K??f??lian, D. Keitel, J. S. Key, S. Khadka, F. Y. Khalili, S. Khan, E. A. Khazanov, N. Khetan, M. Khursheed, N. Kijbunchoo, C. Kim, J. C. Kim, J. Kim, K. Kim, W. S. Kim, Y. -M. Kim, C. Kimball, N. Kimura, M. Kinley-Hanlon, R. Kirchhoff, J. S. Kissel, N. Kita, H. Kitazawa, L. Kleybolte, S. Klimenko, A. M. Knee, T. D. Knowles, E. Knyazev, P. Koch, G. Koekoek, Y. Kojima, K. Kokeyama, S. Koley, P. Kolitsidou, M. Kolstein, K. Komori, V. Kondrashov, A. K. H. Kong, A. Kontos, N. Koper, M. Korobko, K. Kotake, M. Kovalam, D. B. Kozak, C. Kozakai, R. Kozu, V. Kringel, N. V. Krishnendu, A. Kr??lak, G. Kuehn, F. Kuei, P. Kuijer, A. Kumar, P. Kumar, Rahul Kumar, Rakesh Kumar, J. Kume, K. Kuns, C. Kuo, H-S. Kuo, Y. Kuromiya, S. Kuroyanagi, K. Kusayanagi, S. Kuwahara, K. Kwak, P. Lagabbe, D. Laghi, E. Lalande, T. L. Lam, A. Lamberts, M. Landry, B. B. Lane, R. N. Lang, J. Lange, B. Lantz, I. La Rosa, A. Lartaux-Vollard, P. D. Lasky, M. Laxen, A. Lazzarini, C. Lazzaro, P. Leaci, S. Leavey, Y. K. Lecoeuche, H. K. Lee, H. M. Lee, H. W. Lee, J. Lee, K. Lee, R. Lee, J. Lehmann, A. Lema??tre, M. Leonardi, N. Leroy, N. Letendre, C. Levesque, Y. Levin, J. N. Leviton, K. Leyde, A. K. Y. Li, B. Li, J. Li, K. L. Li, T. G. F. Li, X. Li, C-Y. Lin, F-K. Lin, F-L. Lin, H. L. Lin, L. C. -C. Lin, F. Linde, S. D. Linker, J. N. Linley, T. B. Littenberg, G. C. Liu, J. Liu, K. Liu, X. Liu, F. Llamas, M. Llorens-Monteagudo, R. K. L. Lo, A. Lockwood, L. T. London, A. Longo, D. Lopez, M. Lopez Portilla, M. Lorenzini, V. Loriette, M. Lormand, G. Losurdo, T. P. Lott, J. D. Lough, C. O. Lousto, G. Lovelace, J. F. Lucaccioni, H. L??ck, D. Lumaca, A. P. Lundgren, L. -W. Luo, J. E. Lynam, R. Macas, M. MacInnis, D. M. Macleod, I. A. O. MacMillan, A. Macquet, I. Maga??a Hernandez, C. Magazz??, R. M. 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Nakano, R. Nakashima, Y. Nakayama, V. Napolano, I. Nardecchia, T. Narikawa, L. Naticchioni, B. Nayak, R. K. Nayak, R. Negishi, B. F. Neil, J. Neilson, G. Nelemans, T. J. N. Nelson, M. Nery, P. Neubauer, A. Neunzert, K. Y. Ng, S. W. S. Ng, C. Nguyen, P. Nguyen, T. Nguyen, L. Nguyen Quynh, W. -T. Ni, S. A. Nichols, A. Nishizawa, S. Nissanke, E. Nitoglia, F. Nocera, M. Norman, C. North, S. Nozaki, L. K. Nuttall, J. Oberling, B. D. O???Brien, Y. Obuchi, J. O???Dell, E. Oelker, W. Ogaki, G. Oganesyan, J. J. Oh, K. Oh, S. H. Oh, M. Ohashi, N. Ohishi, M. Ohkawa, F. Ohme, H. Ohta, M. A. Okada, Y. Okutani, K. Okutomi, C. Olivetto, K. Oohara, C. Ooi, R. Oram, B. O???Reilly, R. G. Ormiston, N. D. Ormsby, L. F. Ortega, R. O???Shaughnessy, E. O???Shea, S. Oshino, S. Ossokine, C. Osthelder, S. Otabe, D. J. Ottaway, H. Overmier, A. E. Pace, G. Pagano, M. A. Page, G. Pagliaroli, A. Pai, S. A. Pai, J. R. Palamos, O. Palashov, C. Palomba, H. Pan, K. Pan, P. K. Panda, H. Pang, P. T. H. Pang, C. 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S. Salafia, L. Salconi, M. Saleem, F. Salemi, A. Samajdar, E. J. Sanchez, J. H. Sanchez, L. E. Sanchez, N. Sanchis-Gual, J. R. Sanders, A. Sanuy, T. R. Saravanan, N. Sarin, B. Sassolas, H. Satari, B. S. Sathyaprakash, S. Sato, T. Sato, O. Sauter, R. L. Savage, T. Sawada, D. Sawant, H. L. Sawant, S. Sayah, D. Schaetzl, M. Scheel, J. Scheuer, M. Schiworski, P. Schmidt, S. Schmidt, R. Schnabel, M. Schneewind, R. M. S. Schofield, A. Sch??nbeck, B. W. Schulte, B. F. Schutz, E. Schwartz, J. Scott, S. M. Scott, M. Seglar-Arroyo, T. Sekiguchi, Y. Sekiguchi, D. Sellers, A. S. Sengupta, D. Sentenac, E. G. Seo, V. Sequino, A. Sergeev, Y. Setyawati, T. Shaffer, M. S. Shahriar, B. Shams, L. Shao, A. Sharma, P. Sharma, S. Sharma-Chaudhary, P. Shawhan, N. S. Shcheblanov, S. Shibagaki, M. Shikauchi, R. Shimizu, T. Shimoda, K. Shimode, H. Shinkai, T. Shishido, A. Shoda, D. H. Shoemaker, D. M. Shoemaker, S. ShyamSundar, M. Sieniawska, D. Sigg, L. P. Singer, D. Singh, N. Singh, A. Singha, A. M. 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Tao, L. Tao, E. N. Tapia San Martin, E. N. Tapia San Mart??n, C. Taranto, J. D. Tasson, S. Telada, R. Tenorio, J. E. Terhune, L. Terkowski, M. P. Thirugnanasambandam, M. Thomas, P. Thomas, E. E. Thompson, J. E. Thompson, S. R. Thondapu, K. A. Thorne, E. Thrane, Shubhanshu Tiwari, Srishti Tiwari, V. Tiwari, A. M. Toivonen, K. Toland, A. E. Tolley, T. Tomaru, Y. Tomigami, T. Tomura, M. Tonelli, A. Torres-Forn??, C. I. Torrie, I. Tosta e Melo, D. T??yr??, A. Trapananti, F. Travasso, G. Traylor, M. Trevor, M. C. Tringali, A. Tripathee, L. Troiano, A. Trovato, L. Trozzo, R. J. Trudeau, D. S. Tsai, D. Tsai, K. W. Tsang, T. Tsang, J-S. Tsao, M. Tse, R. Tso, K. Tsubono, S. Tsuchida, L. Tsukada, D. Tsuna, T. Tsutsui, T. Tsuzuki, K. Turbang, M. Turconi, D. Tuyenbayev, A. S. Ubhi, N. Uchikata, T. Uchiyama, R. P. Udall, A. Ueda, T. Uehara, K. Ueno, G. Ueshima, C. S. Unnikrishnan, F. Uraguchi, A. L. Urban, T. Ushiba, A. Utina, H. Vahlbruch, G. Vajente, A. Vajpeyi, G. Valdes, M. Valentini, V. 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Williamson, J. L. Willis, B. Willke, D. J. Wilson, W. Winkler, C. C. Wipf, T. Wlodarczyk, G. Woan, J. Woehler, J. K. Wofford, I. C. F. Wong, C. Wu, D. S. Wu, H. Wu, S. Wu, D. M. Wysocki, L. Xiao, W-R. Xu, T. Yamada, H. Yamamoto, Kazuhiro Yamamoto, Kohei Yamamoto, T. Yamamoto, K. Yamashita, R. Yamazaki, F. W. Yang, L. Yang, Y. Yang, Yang Yang, Z. Yang, M. J. Yap, D. W. Yeeles, A. B. Yelikar, M. Ying, K. Yokogawa, J. Yokoyama, T. Yokozawa, J. Yoo, T. Yoshioka, Hang Yu, Haocun Yu, H. Yuzurihara, A. Zadro??ny, M. Zanolin, S. Zeidler, T. Zelenova, J. -P. Zendri, M. Zevin, M. Zhan, H. Zhang, J. Zhang, L. Zhang, T. Zhang, Y. Zhang, C. Zhao, G. Zhao, Y. Zhao, Yue Zhao, Y. Zheng, R. Zhou, Z. Zhou, X. J. Zhu, Z. -H. Zhu, A. B. Zimmerman, M. E. Zucker, and J. Zweizig
- Abstract
We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTC-2020 March 27 17:00 UTC). We conduct two independent searches: A generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate.
- Published
- 2022
21. Space-to-space very low frequency radio transmission in the magnetosphere using the DSX and Arase satellites
- Author
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İnan, Umran Savaş (ORCID 0000-0001-5837-5807 & YÖK ID 177880), McCollough, J.P.; Miyoshi, Y.; Ginet, G.P.; Johnston, W.R.; Su, Y.J.; Starks, M.J.; Kasahara, Y.; Kojima, H.; Matsuda, S.; Shinohara, I.; Song, P.; Reinisch, B.W.; Galkin, I.A.; Lauben, D.S.; Linscott, I.; Ling, A.G.; Allgeier, S.; Lambour, R.; Schoenberg, J.; Gillespie, W.; Stelmash, S.; Roche, K.; Sinclair, A.J.; Sanchez, J.C.; Pedinotti, G.F.; Langhals, J.T., College of Engineering, Department of Electrical and Electronics Engineering, İnan, Umran Savaş (ORCID 0000-0001-5837-5807 & YÖK ID 177880), McCollough, J.P.; Miyoshi, Y.; Ginet, G.P.; Johnston, W.R.; Su, Y.J.; Starks, M.J.; Kasahara, Y.; Kojima, H.; Matsuda, S.; Shinohara, I.; Song, P.; Reinisch, B.W.; Galkin, I.A.; Lauben, D.S.; Linscott, I.; Ling, A.G.; Allgeier, S.; Lambour, R.; Schoenberg, J.; Gillespie, W.; Stelmash, S.; Roche, K.; Sinclair, A.J.; Sanchez, J.C.; Pedinotti, G.F.; Langhals, J.T., College of Engineering, and Department of Electrical and Electronics Engineering
- Abstract
Very low frequency (VLF) waves (about 3-30 kHz) in the Earth's magnetosphere interact strongly with energetic electrons and are a key element in controlling dynamics of the Van Allen radiation belts. Bistatic very low frequency (VLF) transmission experiments have recently been conducted in the magnetosphere using the high-power VLF transmitter on the Air Force Research Laboratory's Demonstration and Science Experiments (DSX) spacecraft and an electric field receiver onboard the Japan Aerospace Exploration Agency's Arase (ERG) spacecraft. On 4 September 2019, the spacecraft came within 410 km of each other and were in geomagnetic alignment. During this time, VLF signals were successfully transmitted from DSX to Arase, marking the first successful reception of a space-to-space VLF signal. Arase measurements were consistent with field-aligned propagation as expected from linear cold plasma theory. Details of the transmission event and comparison to VLF propagation model predictions are presented. The capability to directly inject VLF waves into near-Earth space provides a new way to study the dynamics of the radiation belts, ushering in a new era of space experimentation., Air Force Research Laboratory’s Space Vehicles Directorate; Japan Society for the Promotion of Science (JSPS) Grants-in-Aid-for Scientific Research
- Published
- 2022
22. Integration of silicon-vacancy centers in nanodiamonds with an optical nanofiber
- Author
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Ramachandrarao Yalla, Y. Kojima, Y. Fukumoto, H. Suzuki, O. Ariyada, K. Muhammed Shafi, Kali P. Nayak, and Kohzo Hakuta
- Subjects
inorganic chemicals ,Quantum Physics ,Physics and Astronomy (miscellaneous) ,animal diseases ,technology, industry, and agriculture ,virus diseases ,FOS: Physical sciences ,Quantum Physics (quant-ph) ,complex mixtures - Abstract
We experimentally demonstrate the integration of silicon-vacancy centers in nanodiamonds (SiV-NDs) with an optical nanofiber (ONF). We grow SiV-NDs on seed NDs dispersed on a quartz substrate using a microwave plasma-assisted chemical vapor deposition method. First, we search and characterize SiV-NDs on a quartz substrate using an inverted confocal microscope and an atomic force microscope (AFM). Subsequently, we pick up SiV-NDs from the quartz substrate and deposit them on the surface of a free-standing ONF using the AFM tip. The fluorescence emission spectrum, photon count rate, and intensity correlations for SiV-NDs are systematically measured., Comment: 6 pages, 4 figures
- Published
- 2022
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23. Ground-based millimeter-wave observation of stratospheric ClO over Atacama, Chile in the mid-latitude Southern Hemisphere
- Author
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T. Kuwahara, T. Nagahama, H. Maezawa, Y. Kojima, H. Yamamoto, T. Okuda, N. Mizuno, H. Nakane, Y. Fukui, and A. Mizuno
- Subjects
Environmental engineering ,TA170-171 ,Earthwork. Foundations ,TA715-787 - Abstract
We have performed ground-based measurements of stratospheric chlorine monoxide (ClO) during the summer in 2009 over the Atacama highland, Chile, a new observing site in the mid-latitude region in the Southern Hemisphere, by using a millimeter-wave spectroscopic radiometer. The radiometer, equipped with a superconducting receiver and a digital Fourier spectrometer, was developed by Nagoya University, and the new observing system provides us high sensitivity and stable performance to measure the very weak ClO lines. The receiver noise temperature of the superconducting receiver is 170 K in DSB. To reveal the diurnal variation of ClO, we retrieved the vertical mixing ratio profiles by the weighted-damped least-squares algorithm applied for the spectral data at 203 GHz obtained between 5 and 16 December 2009. The total error on the retrieval is estimated to be 20% to 30% in an altitude range from 40 km to 50 km. The amplitude of the diurnal variation is estimated as 33% of the daytime average at 40 km. The observed time variation shows a pattern similar to that of the previous works observed in the northern mid-latitude region.
- Published
- 2012
- Full Text
- View/download PDF
24. Combination gemcitabine plus S-1 versus gemcitabine plus cisplatin for advanced/recurrent biliary tract cancer: the FUGA-BT (JCOG1113) randomized phase III clinical trial
- Author
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Ken Kamata, R. Sugimoto, Hiroki Hara, Tatsuya Yamashita, Naohiro Okano, Hiroaki Yanagimoto, Masataka Ikeda, Masato Ozaka, Chigusa Morizane, Junji Furuse, Hiroyuki Miyakawa, Kazuhiko Shioji, Junki Mizusawa, Kazuya Sugimori, Keita Wada, Naoya Kato, Ayumu Hosokawa, Shoji Nakamori, Ken Kawabe, Tomohisa Iwai, Tatsuya Ioka, Toshio Nakagohri, Kazutoshi Tobimatsu, Hiroshi Ishii, Makoto Ueno, Hironori Yamaguchi, Seigo Yukisawa, Yasuyuki Kawamoto, T. Okusaka, Y. Kojima, K. Yane, Nobumasa Mizuno, Hiroshi Katayama, Kenji Nakamura, Ken Shimizu, Akira Fukutomi, and Akinori Asagi
- Subjects
Adult ,Male ,0301 basic medicine ,medicine.medical_specialty ,Vomiting ,Nausea ,Deoxycytidine ,Gastroenterology ,Disease-Free Survival ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Randomized controlled trial ,law ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,Clinical endpoint ,medicine ,Mucositis ,Humans ,Aged ,Tegafur ,business.industry ,Standard treatment ,Hazard ratio ,Hematology ,Middle Aged ,medicine.disease ,Gemcitabine ,Drug Combinations ,Oxonic Acid ,Biliary Tract Neoplasms ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,Female ,Cisplatin ,medicine.symptom ,business ,medicine.drug - Abstract
Background Gemcitabine plus cisplatin (GC) is the standard treatment of advanced biliary tract cancer (BTC); however, it causes nausea, vomiting, and anorexia, and requires hydration. Gemcitabine plus S-1 (GS) reportedly has equal to, or better, efficacy and an acceptable toxicity profile. We aimed to confirm the non-inferiority of GS to GC for patients with advanced/recurrent BTC in terms of overall survival (OS). Patients and methods We undertook a phase III randomized trial in 33 institutions in Japan. Eligibility criteria included chemotherapy-naive patients with recurrent or unresectable BTC, an Eastern Cooperative Oncology Group Performance Status of 0−1, and adequate organ function. The calculated sample size was 350 with a one-sided α of 5%, a power of 80%, and non-inferiority margin hazard ratio (HR) of 1.155. The primary end point was OS, while the secondary end points included progression-free survival (PFS), response rate (RR), adverse events (AEs), and clinically significant AEs defined as grade ≥2 fatigue, anorexia, nausea, vomiting, oral mucositis, or diarrhea. Results Between May 2013 and March 2016, 354 patients were enrolled. GS was found to be non-inferior to GC [median OS: 13.4months with GC and 15.1months with GS, HR, 0.945; 90% confidence interval (CI), 0.78–1.15; P=0.046 for non-inferiority]. The median PFS was 5.8months with GC and 6.8months with GS (HR 0.86; 95% CI 0.70–1.07). The RR was 32.4% with GC and 29.8% with GS. Both treatments were generally well-tolerated. Clinically significant AEs were observed in 35.1% of patients in the GC arm and 29.9% in the GS arm. Conclusions GS, which does not require hydration, should be considered a new, convenient standard of care option for patients with advanced/recurrent BTC. Clinical Trial number This trial has been registered with the UMIN Clinical Trials Registry (http://www.umin.ac.jp/ctr/index.htm), number UMIN000010667.
- Published
- 2019
25. MSR30 Modelling Monthly Migraine Day Distribution: A Case Study of Fremanezumab Japanese-Korean Clinical Trials for Migraine Prevention
- Author
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X Wang, K Yamato, Y Kojima, J Paris, E Peterse, C Simons, A Chatterjee, and C Bennison
- Subjects
Health Policy ,Public Health, Environmental and Occupational Health - Published
- 2022
26. Tracheomalacia
- Author
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Y Kojima, K Takeyabu, M Kimura, A Matunaga, H Arisato, Y Ohata, and M Sato
- Subjects
Trachea ,Bronchoscopy ,Humans ,General Medicine ,Tracheomalacia - Published
- 2021
27. Development of a novel diagnostic model for urological cancers using comprehensive N-glycan signatures of serum immunoglobulins with a machine learning approach
- Author
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H. Iwamura, T. Yoneyama, H. Kodama, K. Ozaki, Y. Ozaki, K. Okita, S. Konishi, T. Narita, N. Fujita, Y. Kojima, T. Okamoto, Y. Tobisawa, H. Yamamoto, S. Hatakeyama, Y. Hashimoto, and C. Ohyama
- Subjects
Urology - Published
- 2022
28. The association between human gut microbiota and prostate enlargement
- Author
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K. Takezawa, K. Fujita, M. Matsushita, D. Motooka, K. Hatano, E. Banno, N. Shimizu, T. Takao, S. Takada, K. Okada, S. Fukuhara, H. Kiuchi, H. Uemura, S. Nakamura, Y. Kojima, and N. Nonomura
- Subjects
Urology - Published
- 2022
29. P10 Evaluating the Correlation between Monthly Migraine Days and Quality-of-Life: Utility Analyses to Inform a Japanese Cost-Effectiveness Model for Fremanezumab in Migraine
- Author
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E Peterse, C Bennison, JJ Paris, A Chatterjee, X Wang, Y Kojima, and K Yamato
- Subjects
Health Policy ,Public Health, Environmental and Occupational Health - Published
- 2022
30. An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor
- Author
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Sanjivini V. Jacob, John D. Reith, Angerika Y. Kojima, William D. Williams, Chen Liu, and Lizette Vila Duckworth
- Subjects
Pathology ,RB1-214 - Abstract
Systemic inflammatory myofibroblastic tumor is an exceedingly rare entity. A 45-year-old Hispanic female presented with a 6-month history of left-sided thigh pain, low back pain, and generalized weakness. PET/CT scan revealed abnormal activity in the liver, adrenal gland, and pancreas. MRI of the abdomen demonstrated two 6-7 cm masses in the liver. MRI of the lumbar spine demonstrated lesions in the L2 to L4 spinous processes, paraspinal muscles, and subcutaneous tissues, as well as an 8 mm enhancing intradural lesion at T11, all thought to be metastatic disease. A biopsy of the liver showed portal tract expansion by a spindle cell proliferation rich in inflammation. Tumor cells showed immunoreactivity for smooth muscle actin and anaplastic lymphoma kinase 1 (ALK1). Tissue from the L5 vertebra showed a process histologically identical to that seen in the liver. FISH analysis of these lesions demonstrated an ALK (2p23) gene rearrangement. The patient was successfully treated with an ALK-inhibitor, Crizotinib, and is now in complete remission. We present the first reported case, to our knowledge, of inflammatory myofibroblastic tumor with systemic manifestations and ALK translocation. This case is a prime example of how personalized medicine has vastly improved patient care through the use of molecular-targeted therapy.
- Published
- 2014
- Full Text
- View/download PDF
31. 937P Multicenter phase II trial of lenvatinib plus hepatic intra-arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma: LEOPARD
- Author
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K. Tsuchiya, Taro Yamashita, Masataka Ikeda, Kazuhiro Nouso, Manabu Morimoto, Y. Kojima, Toshihiko Sato, Hiroshi Aikata, Yoshitaka Inaba, J. Furuse, A. Hiraoka, Sadahisa Ogasawara, Satoshi Shimizu, T. Okusaka, Kazushi Numata, and Masatoshi Kudo
- Subjects
Cisplatin ,medicine.medical_specialty ,Chemotherapy ,business.industry ,medicine.medical_treatment ,Urology ,Hematology ,Intra arterial infusion ,medicine.disease ,chemistry.chemical_compound ,Oncology ,chemistry ,Hepatocellular carcinoma ,medicine ,business ,Lenvatinib ,medicine.drug - Published
- 2021
32. Development of on-board engineering model for 920-MHz earth sensing platform via LEO satellite utilizing feeder-link MIMO technology
- Author
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F. YAMASHITA, D. GOTO, Y. KOJIMA, K. ITOKAWA, K. SAKAMOTO, Y. FUJINO, C. KATO, M. NAKADAI, M. YAJIMA, and T. IWATA
- Published
- 2021
33. Oncologic and patient-reported outcomes after robot-assisted radical prostatectomy in men 75 years or older
- Author
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S. Hatakeyama, K. Togashi, T. Okamoto, Y. Kojima, H. Iwamura, N. Fujita, T. Narita, T. Hamaya, T. Yoneyama, H. Yamamoto, Y. Hashimoto, and C. Ohyama
- Subjects
medicine.medical_specialty ,Prostatectomy ,business.industry ,Urology ,General surgery ,medicine.medical_treatment ,medicine ,business - Published
- 2021
34. Probabilistic teleportation of a quantum dot spin qubit
- Author
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Tomohiro Otsuka, Jun Yoneda, Arne Ludwig, Stephen D. Bartlett, Y. Kojima, Kenta Takeda, Seigo Tarucha, Takashi Nakajima, Akito Noiri, Andreas D. Wieck, and Sen Li
- Subjects
Computer Networks and Communications ,QC1-999 ,FOS: Physical sciences ,Data_CODINGANDINFORMATIONTHEORY ,02 engineering and technology ,Quantum entanglement ,01 natural sciences ,symbols.namesake ,Pauli exclusion principle ,Computer Science::Emerging Technologies ,Quantum mechanics ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,0103 physical sciences ,Computer Science (miscellaneous) ,Hardware_ARITHMETICANDLOGICSTRUCTURES ,010306 general physics ,Spin-½ ,Quantum computer ,Physics ,Quantum Physics ,Condensed Matter - Mesoscale and Nanoscale Physics ,TheoryofComputation_GENERAL ,Statistical and Nonlinear Physics ,QA75.5-76.95 ,021001 nanoscience & nanotechnology ,Computational Theory and Mathematics ,Quantum dot ,ComputerSystemsOrganization_MISCELLANEOUS ,Electronic computers. Computer science ,Qubit ,symbols ,Quantum algorithm ,Quantum Physics (quant-ph) ,0210 nano-technology ,Quantum teleportation - Abstract
Electron spins in semiconductor quantum dots have been intensively studied for implementing quantum computation and high-fidelity single- and two-qubit operations have recently been achieved. Quantum teleportation is a three-qubit protocol exploiting quantum entanglement and it serves as an essential primitive for more sophisticated quantum algorithms. Here we demonstrate a scheme for quantum teleportation based on direct Bell measurement for a single-electron spin qubit in a triple quantum dot utilizing the Pauli exclusion principle to create and detect maximally entangled states. The single spin polarization is teleported from the input qubit to the output qubit. We find this fidelity is primarily limited by singlet–triplet mixing, which can be improved by optimizing the device parameters. Our results may be extended to quantum algorithms with a larger number of semiconductor spin qubits.
- Published
- 2020
35. Determination of Non-Uniform Microscopic Distributions of Thermal Strains in Glass-Fiber Cloth/Epoxy Laminates Using DIC
- Author
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Y. Kojima, Hiroaki Makino, Takashi Ohta, and Hiroshi Hohjo
- Subjects
Digital image correlation ,Materials science ,Microscope ,Silicon ,Mechanical Engineering ,Glass fiber ,chemistry.chemical_element ,02 engineering and technology ,Epoxy ,01 natural sciences ,Thermal expansion ,law.invention ,010309 optics ,020303 mechanical engineering & transports ,0203 mechanical engineering ,chemistry ,Mechanics of Materials ,law ,visual_art ,0103 physical sciences ,Thermal ,visual_art.visual_art_medium ,Deformation (engineering) ,Composite material - Abstract
In electronic components, various materials with different thermal expansion coefficients are joined. For reliability evaluation, it is important to understand the thermal stresses and strains caused by such thermal expansion mismatches. In this investigation, the microscopic thermal strain distribution during the heating of glass-fiber cloth/epoxy laminates was measured via the digital image correlation method using a micro-speckle pattern under the microscope. The micro-speckle patterns were painted on a base coat to track the deformation of the epoxy resin during thermal expansion. The trackability was validated by a silicon single-crystal standard reference material. The results demonstrate that the non-uniform thermal strain distribution reflects the periodic structure of the glass-fiber cloth material at temperatures ranging from 30 °C to 140 °C, i.e., in the region of the laminate surface where the interspaces among the glass-fiber bundles are wide, the thermal strain during heating is large, but the thermal strain on the glass-fiber bundle is small. The thermal strain in the thickness direction is large in the resin part and small on the glass-fiber bundle.
- Published
- 2018
36. Immediate Interlocking Nailing versus External Fixation Followed by Delayed Interlocking Nailing for Gustilo Type IIIB Open Tibial Fractures
- Author
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HJ Park, M Uchino, K Nakamura, M Ueno, Y Kojima, M Itoman, K Yokoyama, T Suzuki, and M Nemoto
- Subjects
Orthopedic surgery ,RD701-811 - Abstract
Purpose. To compare immediate interlocking nailing with external fixation followed by delayed interlocking nailing, for Gustilo type IIIB open tibial fractures. Methods. 23 patients with Gustilo IIIB open tibial fractures were treated with either immediate unreamed interlocking nailing (n=9) or external fixation followed by delayed unreamed interlocking nailing (n=14). Patient age, sex ratio, fracture site, fracture type, and severity were similar in both groups. The time to union, deep infection rate, and nonunion rate in the 2 groups were compared. Results. In the immediate and delayed nailing groups, respective mean times to union were 21 (standard deviation [SD], 14) months and 14 (SD, 8) months; nonunion rates were 44% (4/9) and 36% (5/14), and deep infection rates were 22% (2/9) and 7% (1/14). All corresponding differences were not statistically significant. Conclusion. Prospective, randomised, multicentre studies are needed to assess whether there are significant differences between the 2 treatment methods.
- Published
- 2007
- Full Text
- View/download PDF
37. Real-time visualization of cardiac cell beating behaviour on polymer diffraction gratings
- Author
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Koichiro Tanaka, Easan Sivaniah, Y. Kojima, K. Ono, O. Lang, Andrew Harold Gibbons, and Masateru M. Ito
- Subjects
0301 basic medicine ,chemistry.chemical_classification ,Materials science ,genetic structures ,Polydimethylsiloxane ,business.industry ,General Chemical Engineering ,Substrate (chemistry) ,Nanotechnology ,General Chemistry ,Polymer ,Cardiac cell ,Real time visualization ,03 medical and health sciences ,chemistry.chemical_compound ,030104 developmental biology ,chemistry ,Optoelectronics ,business ,Layer (electronics) ,Diffraction grating - Abstract
Cardiotoxicity is one of the major adverse effects of pharmaceuticals and new methods are sought for measuring cell properties with high-throughput. Here we report a flexible diffraction grating device fabricated from polydimethylsiloxane coated with platinum to make optically responsive cell culturing substrates. Cardiomyocytes from neonatal Sprague-Dawley rats were isolated and seeded upon the surface of the PDMS diffraction grating using fibronectin as the binding protein. On this substrate the cells formed a confluent layer and continued beating synchronously. By measuring the optical change of the PDMS substrate, the beating of the confluent layer could be monitored. Epinephrine was introduced to the cell environment and the change in beating frequency was measured and visualized. This flexible diffraction grating substrate provides a new way for remotely measuring cell beating properties during high-throughput testing and within miniaturized or confined device architectures.
- Published
- 2017
38. Source modeling of the mid-scale crustal earthquake by forward modeling using the empirical Green’s function method
- Author
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Y. Kojima and T. Ikeda
- Subjects
symbols.namesake ,Scale (ratio) ,Green's function ,symbols ,Geology ,Seismology ,Source modeling - Published
- 2019
39. Towards quantum teleportation with quantum-dot spin qubits
- Author
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Takashi Nakajima, Arne Ludwig, Y. Kojima, A. Noiri, Stephen D. Bartlett, Andreas D. Wieck, Kenta Takeda, Jun Yoneda, Sen Li, Tomohiro Otsuka, and Seigo Tarucha
- Subjects
Materials science ,Quantum Physics ,Quantum entanglement ,symbols.namesake ,Computer Science::Emerging Technologies ,Pauli exclusion principle ,Quantum dot ,Qubit ,Quantum mechanics ,symbols ,Quantum algorithm ,Quantum information science ,Quantum teleportation ,Quantum computer - Abstract
Electron spins in quantum dots are a promising building block for quantum computing. While fundamental gate operations on single and two qubits have been demonstrated, quantum algorithms utilizing three or more qubits have not tested so far. Quantum teleportation is one of the important milestones that can be implemented with three qubits, because it explicitly makes use of quantum entanglement and is applicable to quantum communication and quantum computing. The key of Quantum teleportation is to prepare one of maximally entangled states and perform projection measurement onto them. These can be, in principle, implemented by using a two-qubit gate operation and a series of single-qubit operations. However, realization of those controls remains challenging in three-spin-qubit systems. Instead, the Pauli spin blockade can be utilized to prepare and selectively measure one of the maximally entangled state. This significantly simplifies partial implementation of the quantum teleportation protocol.
- Published
- 2019
40. Satellite experiments on direct spectrum division transmission over multiple transponders [International Communications Satellite Systems Conference]
- Author
-
H. Shibayama, D. Goto, Y. Kojima, H. Kobashi, F. Yamashita, and D. Haraguchi
- Subjects
biology ,Transmission (telecommunications) ,Computer science ,Communications satellite ,Satellite (biology) ,Division (mathematics) ,biology.organism_classification ,Remote sensing - Published
- 2019
41. Predominant reaction products and dielectric breakdown properties of gas mixtures consisting of SF6 and ablation products of C2F4/BN in the temperature range of 300–3000 K
- Author
-
N. Kodama, Yasunobu Yokomizu, M. Kuroda, Y. Kojima, Hajime Urai, T. Ishii, and M. Terada
- Subjects
Materials science ,Acoustics and Ultrasonics ,Dielectric strength ,medicine.medical_treatment ,medicine ,Analytical chemistry ,Atmospheric temperature range ,Condensed Matter Physics ,Ablation ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Reaction product - Abstract
For a high voltage SF6 circuit breaker equipped with a boron nitride (BN)-filled polytetrafluoroethylene ((C2F4) n ) nozzle, the predominant reaction products in a high-temperature SF6 mixture with vapor decomposition of C2F4 and BN at temperatures of 300–3000 K are determined based on calculations of equilibrium composition. The calculation is performed by considering the molecular products obtained by chemical reactions with boron atoms (e.g. BN, BS, BC, BF, BF2 and BF3), nitrogen atoms (e.g. N2, N3, CN, NS, NF, NF2 and NF3) and carbon atoms (e.g. CS, CS2, C2F4, CF2, CF3 and CF4). The results obtained for the C2F4–BN molar fraction X C F B N of 20%–80% reveal that BF3, N2 and CF4, the molecules originating from the nozzle material, are produced at high molar fractions over a range of 300–3000 K. Such an evaluation of the gas composition allows the derivation of a reduced collision ionization coefficient α/N and a reduced electron attachment coefficient η/N of the gas, considering various electron impact processes such as BF3 + e → BF2 + F− and CF4 + e → CF3 + F−. The evaluation subsequently enables us to determine a critical reduced electric field strength E c r / N causing ( α − η ) / N = 0 . The results suggest that the decomposed C2F4–BN mixture at X C F B N of 80% causes the reduction of E c r / N to 110 Td in the range of 1000–2000 K at a gas pressure of 1.0 MPa. This strength E c r / N is 20 Td lower than that determined separately for the SF6 gas mixture with only 80% C2F4 vapor decomposition, because of the CF4 molar fraction reduction in the SF6/C2F4–BN mixture.
- Published
- 2021
42. Sorafenib plus hepatic arterial infusion chemotherapy with cisplatin versus sorafenib for advanced hepatocellular carcinoma: randomized phase II trial
- Author
-
Shoji Nakamori, Tosiya Sato, Shuichi Kaneko, Masafumi Ikeda, Kohichiroh Yasui, Masatoshi Kudo, Satoshi Shimizu, Keiko Sato, J. Furuse, Takuji Okusaka, Takumi Ohmura, Manabu Morimoto, Yoshitaka Inaba, Y. Kojima, T. Tahara, Atsushi Hagihara, Hiroshi Ishii, and R. Sugimoto
- Subjects
Oncology ,Sorafenib ,medicine.medical_specialty ,randomized phase II trial ,cisplatin ,hepatic arterial infusion chemotherapy ,urologic and male genital diseases ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Gastrointestinal Tumors ,Hepatic arterial infusion chemotherapy ,Medicine ,heterocyclic compounds ,neoplasms ,Cisplatin ,business.industry ,Original Articles ,hepatocellular carcinoma ,Hematology ,medicine.disease ,female genital diseases and pregnancy complications ,digestive system diseases ,030220 oncology & carcinogenesis ,Hepatocellular carcinoma ,sorafenib ,030211 gastroenterology & hepatology ,business ,Standard therapy ,medicine.drug - Abstract
In a randomized phase II study of sorafenib plus hepatic arterial infusion chemotherapy with cisplatin in comparison with sorafenib alone in patients with advanced hepatocellular carcinoma, it yielded favorable overall survival when compared with sorafenib alone. This is the first report of its effectiveness in relation to the overall survival in comparison with that of sorafenib alone in patients with advanced hepatocellular carcinoma., Background Sorafenib (Sor) is acknowledged as a standard therapy for advanced hepatocellular carcinoma (HCC). This trial was conducted to evaluate the effect of addition of hepatic arterial infusion chemotherapy with cisplatin (SorCDDP) to Sor for the treatment of advanced HCC. Patients and methods We conducted a multicenter open-labeled randomized phase II trial in chemo-naïve patients with advanced HCC with Child-Pugh scores of 5–7. Eligible patients were randomly assigned 2:1 to receive SorCDDP (sorafenib: 400 mg bid; cisplatin: 65 mg/m2, day 1, every 4–6 weeks) or Sor (400 mg bid). The primary end point was overall survival. Results A total of 108 patients were randomized (Sor, n = 42; SorCDDP, n = 66). The median survival in the Sor and SorCDDP arms were 8.7 and 10.6 months, respectively [stratified hazard ratio (95% confidence interval), 0.60 (0.38–0.96), P = 0.031]. The median time to progression and the response rate were, respectively, 2.8 months and 7.3% in the Sor arm and 3.1 months and 21.7% in the SorCDDP arm. The adverse events were more frequent in the SorCDDP arm than in the Sor arm, but well-tolerated. Conclusion SorCDDP yielded favorable overall survival when compared with Sor in patients with advanced HCC. Clinical Trial registration UMIN-CTR (http://www.umin.ac.jp/ctr/index-j.htm), identification number: UMIN000005703.
- Published
- 2016
43. ARE NUTRIENT CONTRIBUTIONS OF FOODS CONSISTENT WITH FOOD GROUP DEFINITIONS? THE THREE-COLOR CLASSIFICATION SYSTEM FOR FOOD GROUPS IN JAPANESE SCHOOL LUNCHES
- Author
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R. Akamatsu and Y. Kojima
- Subjects
Food group ,Nutrient ,Geography ,business.industry ,business ,Agricultural economics ,Biotechnology - Published
- 2016
44. Experimental and numerical investigation of 2 K heat exchanger for superfluid helium cryogenic systems at KEK
- Author
-
Kazufumi Hara, H. Nakai, Y. Kojima, Hirotaka Shimizu, A. Kumar, Teruya Honma, and K. Nakanishi
- Subjects
Materials science ,Heat exchanger ,Physics::Accelerator Physics ,Mechanics ,Superfluid helium-4 - Abstract
Superfluid helium cryogenic systems at KEK are constructed for research and development of cryomodules of the compact Energy Recovery Linac (cERL) and the International Linear Collider (ILC). The niobium superconducting radio frequency (SRF) cavities in cERL and ILC operate at temperatures of 2.0 K or below. The SRF cavities are cooled with saturated superfluid helium, which is another phase of the liquid helium (LHe), when it is cooled below 2.17 K under saturation condition. To produce superfluid helium continuously, a Joule-Thomson (JT) valve is employed in the cryogenic system. Also, a 2 K heat exchanger (2K HX) is introduced in series with the JT valve to recover the coldness from 2.0 K gaseous helium (GHe) evaporating from the helium tanks of the SRF cavities. This increases the production rate of superfluid helium by reducing the incoming LHe temperature from 4.4 K to 2.2 K or above before the JT valve. At KEK, we have a 2K HX consisting of a helical coil and laminated fins for thermal loads up to 100 W. Its performance needs to be determined and is characterized by a factor known as effectiveness, which is the ratio of actual heat transfer to the maximum possible heat transfer between the fluids. The performance of the 2K HX has been determined experimentally using the heat exchanger test stand and numerically by computational fluid dynamics (ANSYS CFX®), respectively. In the heat exchanger test stand, the mass flow rate of incoming LHe is kept identical to the outgoing GHe through the 2K HX, using the level and pressure control of superfluid helium. An electric cartridge heater is immersed in the superfluid helium to vary the mass flow rate of evaporating superfluid helium. In the future, the optimization of the 2K HX design will be performed to improve its performance.
- Published
- 2020
45. A fast quantum interface between different spin qubit encodings
- Author
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Giles Allison, Arne Ludwig, Akito Noiri, Kenta Takeda, Tomohiro Otsuka, Jun Yoneda, Daniel Loss, Peter Stano, Y. Kojima, Andreas D. Wieck, Takashi Nakajima, Matthieu R. Delbecq, Shinichi Amaha, Seigo Tarucha, Kento Kawasaki, RIKEN - Institute of Physical and Chemical Research [Japon] (RIKEN), Laboratoire Pierre Aigrain (LPA), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), The University of Tokyo (UTokyo), Tokyo University of Science [Tokyo], Ruhr-Universität Bochum [Bochum], and University of Basel (Unibas)
- Subjects
Coherence time ,Quantum information ,Dephasing ,Science ,FOS: Physical sciences ,General Physics and Astronomy ,02 engineering and technology ,Topology ,01 natural sciences ,General Biochemistry, Genetics and Molecular Biology ,Article ,Computer Science::Emerging Technologies ,[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph] ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,0103 physical sciences ,Hardware_ARITHMETICANDLOGICSTRUCTURES ,lcsh:Science ,010306 general physics ,Quantum ,Spin-½ ,Quantum computer ,Physics ,Multidisciplinary ,Condensed Matter - Mesoscale and Nanoscale Physics ,Quantum dots ,General Chemistry ,Quantum Physics ,021001 nanoscience & nanotechnology ,Orders of magnitude (time) ,Hybrid system ,Qubit ,lcsh:Q ,0210 nano-technology ,Qubits - Abstract
Single-spin qubits in semiconductor quantum dots hold promise for universal quantum computation with demonstrations of a high single-qubit gate fidelity above 99.9% and two-qubit gates in conjunction with a long coherence time. However, initialization and readout of a qubit is orders of magnitude slower than control, which is detrimental for implementing measurement-based protocols such as error-correcting codes. In contrast, a singlet-triplet qubit, encoded in a two-spin subspace, has the virtue of fast readout with high fidelity. Here, we present a hybrid system which benefits from the different advantages of these two distinct spin-qubit implementations. A quantum interface between the two codes is realized by electrically tunable inter-qubit exchange coupling. We demonstrate a controlled-phase gate that acts within 5.5 ns, much faster than the measured dephasing time of 211 ns. The presented hybrid architecture will be useful to settle remaining key problems with building scalable spin-based quantum computers., The race to produce a quantum computer has driven the development of many different qubit designs with different benefits and drawbacks. Noiri et al. demonstrate a hybrid device with two coupled semiconductor spin qubits of different designs, which should allow each qubit’s advantages to be exploited.
- Published
- 2018
46. A blindsnake that decapitates its termite prey
- Author
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T. Mizuno and Y. Kojima
- Subjects
Indotyphlops braminus ,Feeding behavior ,Predatory behavior ,biology ,Ecology ,digestive, oral, and skin physiology ,Zoology ,Ingestion ,Animal Science and Zoology ,biology.organism_classification ,Typhlopidae ,Ecology, Evolution, Behavior and Systematics ,Predation - Abstract
Almost all snakes swallow their prey whole. However, a few species are known as exceptions. Two species of Asian crab-eating snakes tear off crab legs and ingest them one at a time to eat prey that is otherwise too large. Two species of leptotyphlopid blindsnakes break off the head of termites or suck abdominal contents of termites, discarding remains of termites. Here, we show that a typhlopid blindsnake Indotyphlops braminus decapitates its termite prey and consumes only the thorax and abdomen. In our feeding trials, I. braminus decapitated a median of 47% of termites they eat, while swallowing the remaining termites whole. Decapitation did not affect ingestion speed, and therefore, it is unlikely that decapitation assists for fast ingestion. Ingested termite heads often remain undigested in the feces, implying that the decapitation functions to remove an indigestible part of termites. Decapitation might also be related to circumvention of chemical defenses of termites because termite heads often contain toxic compounds. These observations showed unusual feeding behavior used by a basal snake, which could be associated with removal of indigestible and/or toxic parts of prey items.
- Published
- 2015
47. Diffuse Liver Metastasis of Small-Cell Lung Cancer Presenting as Acute Liver Failure and Diagnosed by Transjugular Liver Biopsy: A Rare Case in Whom Nodular Lesions Were Detected by Enhanced CT Examination
- Author
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M. Iikura, Toru Igari, T. Masuda, M. Kobayakawa, T. Sakurai, M. Imamura, E. Kihira, M. Yanase, Naoyoshi Nagata, Shintaro Mikami, Y. Nozaki, Y. Kojima, S. Mishima, N. Masaki, Kazuhiro Watanabe, T. Nakayama, C. Yokoi, H. Sugiyama, H. Nakamura, Y. Egami, J. Akiyama, K. Hasuo, R. Koketsu, and H. Kaname
- Subjects
medicine.medical_specialty ,Enhanced ct ,business.industry ,Gastroenterology ,Liver failure ,Diffuse liver metastasis ,medicine.disease ,Small-cell lung cancer ,respiratory tract diseases ,Metastasis ,Nodular lesions ,Rare case ,medicine ,Transjugular liver biopsy ,lcsh:Diseases of the digestive system. Gastroenterology ,Non small cell ,Radiology ,lcsh:RC799-869 ,Published online: April, 2015 ,Lung cancer ,business ,Acute liver failure - Abstract
Small-cell lung cancer (SCLC) is a subgroup of lung cancer with a high frequency of liver metastasis, which is a predictor of poor prognosis. Diffuse liver metastases of SCLC with no visible nodular lesions in the liver when examined using computed tomography (CT) are relatively rare; however, a few cases with rapid progression to acute liver failure that were diagnosed after death have been reported. In this paper, we report a 63-year-old man with diffuse liver metastases of SCLC that were histologically diagnosed using a transjugular liver biopsy while the patient was alive, even though no lesions were visible during a contrast-enhanced CT examination.
- Published
- 2015
48. A Wide Load Range Switched Capacitor DC-DC Converter with Adaptive Bias Comparator for Ultra-Low-Power Power Management Integrated Circuit
- Author
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Nobutaka Kuroki, Tetsuya Hirose, Hiroki Asano, Y. Kojima, and Masahiro Numa
- Subjects
Ultra low power ,Materials science ,Adaptive bias ,Comparator ,business.industry ,Electrical engineering ,Range (statistics) ,business ,Switched capacitor ,Power management integrated circuit ,Dc dc converter - Published
- 2017
49. An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor
- Author
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Angerika Y. Kojima, John D. Reith, Sanjivini V. Jacob, Lizette Vila Duckworth, Chen Liu, and William D. Williams
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Pathology ,medicine.medical_specialty ,Crizotinib ,medicine.diagnostic_test ,business.industry ,medicine.drug_class ,Case Report ,General Medicine ,Gene rearrangement ,Lesion ,ALK inhibitor ,medicine.anatomical_structure ,Biopsy ,lcsh:Pathology ,medicine ,Anaplastic lymphoma kinase ,Abdomen ,medicine.symptom ,business ,Pancreas ,lcsh:RB1-214 ,medicine.drug - Abstract
Systemic inflammatory myofibroblastic tumor is an exceedingly rare entity. A 45-year-old Hispanic female presented with a 6-month history of left-sided thigh pain, low back pain, and generalized weakness. PET/CT scan revealed abnormal activity in the liver, adrenal gland, and pancreas. MRI of the abdomen demonstrated two 6-7 cm masses in the liver. MRI of the lumbar spine demonstrated lesions in the L2 to L4 spinous processes, paraspinal muscles, and subcutaneous tissues, as well as an 8 mm enhancing intradural lesion at T11, all thought to be metastatic disease. A biopsy of the liver showed portal tract expansion by a spindle cell proliferation rich in inflammation. Tumor cells showed immunoreactivity for smooth muscle actin and anaplastic lymphoma kinase 1 (ALK1). Tissue from the L5 vertebra showed a process histologically identical to that seen in the liver. FISH analysis of these lesions demonstrated an ALK (2p23) gene rearrangement. The patient was successfully treated with an ALK-inhibitor, Crizotinib, and is now in complete remission. We present the first reported case, to our knowledge, of inflammatory myofibroblastic tumor with systemic manifestations and ALK translocation. This case is a prime example of how personalized medicine has vastly improved patient care through the use of molecular-targeted therapy.
- Published
- 2014
50. Formaldehyde production via partial oxidation of methanol over oxides of Cr, Mo and W supported on ceria-zirconia
- Author
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Takayuki Ichikawa, Hafedh Driss, Hiroki Miyaoka, Sharif F. Zaman, Muhammad A. Daous, Lachezar A. Petrov, Abdulrahim A. Al-Zahrani, Y. Kojima, and Hitoshi Inokawa
- Subjects
chemistry.chemical_compound ,chemistry ,Formaldehyde ,Cubic zirconia ,02 engineering and technology ,Partial oxidation ,Methanol ,010402 general chemistry ,021001 nanoscience & nanotechnology ,0210 nano-technology ,01 natural sciences ,0104 chemical sciences ,Nuclear chemistry - Published
- 2018
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