26 results on '"Y. S. POON"'
Search Results
2. Youth Interventions With and Without Supervised Practice: A Second-Order Meta-Analysis
- Author
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Kirsten M. Christensen, Mark Assink, Levi van Dam, Geert-Jan Stams, Cyanea Y. S. Poon, Jeremy Astesano, and Jean E. Rhodes
- Subjects
General Social Sciences ,Social Sciences (miscellaneous) - Published
- 2023
3. Deconstructing 'Risk' in Youth Mentoring Programs: How Environmental Stressors and Presenting Challenges Shape Mentoring Relationship Outcomes
- Author
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Cyanea Y. S. Poon, Carla Herrera, Roger Jarjoura, Samuel D. McQuillin, Thomas E. Keller, and Jean E. Rhodes
- Subjects
Sociology and Political Science ,education ,Developmental and Educational Psychology ,Life-span and Life-course Studies ,Social Sciences (miscellaneous) - Abstract
Youth referred to mentoring programs vary considerably in the range and severity of difficulties (i.e., behavioral, internalizing, social and academic) and environmental challenges they face. However, their patterns of risk and corresponding consequences for mentoring have rarely been investigated. This study draws on data for youth participants in 30 mentoring programs ( n = 2,165, 55.1% females) to examine patterns of presenting challenges. Four profiles emerged using three-step latent profile analyses . Profiles with more intensive symptoms were associated with more environmental stressors. Moreover, there were significant differences between profiles in youth-perceived relationship attributes, including closeness, youth-centeredness, growth focus and mentor-mentee relational health. The profile with the highest externalizing and social challenge indicators scored the lowest across these four relational indices. The results highlight variability of youth risk at baseline, and its differential impact on mentoring relationship outcomes. Implications for mentoring programs are discussed.
- Published
- 2022
4. A <scp>meta‐analysis</scp> of the effects of <scp>after‐school</scp> programmes among youth with marginalized identities
- Author
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Kirsten M. Christensen, Kristen P. Kremer, Cyanea Y. S. Poon, and Jean E. Rhodes
- Subjects
Sociology and Political Science ,Social Psychology - Published
- 2023
5. Author response for 'Contextual antecedents and well‐being indicators associated with children's and adolescents' access to supportive nonparent adults'
- Author
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null Matthew A. Hagler and null Cyanea Y. S. Poon
- Published
- 2023
6. Cross‐age peer mentoring for youth: A meta‐analysis
- Author
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Samantha, Burton, Elizabeth B, Raposa, Cyanea Y S, Poon, Geert Jan J M, Stams, and Jean, Rhodes
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Health (social science) ,Adolescent ,Public Health, Environmental and Occupational Health ,Humans ,Mentoring ,Peer Group ,Applied Psychology ,Program Evaluation - Abstract
Although most mentoring programs for youth are structured around intergenerational relationships, a growing number of programs rely on cross-age peer mentoring. Such programs capitalize on the availability of youth mentors to promote positive outcomes in younger peers. This study used a multilevel meta-analytic approach to estimate the effect size of cross-age peer mentoring programs and evaluate potential moderators of peer mentoring program effectiveness. Analyses included six studies and revealed a medium-sized overall effect of cross-age peer mentoring programs (g = 0.45). Several characteristics moderated effect sizes, with larger effects for programs that were conducted outside of the school setting (i.e., weekend, summer, or in community settings), conducted in urban settings, and had moderate/high levels of adult oversight and supervision. Results highlight the potential benefits of cross-age peer mentoring for youth.
- Published
- 2021
7. Changes in psychosocial resources as predictors of posttraumatic growth: A longitudinal study of low-income, female Hurricane Katrina survivors
- Author
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Jean E. Rhodes, Cyanea Y. S. Poon, Emily Manove, and Sarah R. Lowe
- Subjects
Low income ,Longitudinal study ,Posttraumatic growth ,Public Health, Environmental and Occupational Health ,Article ,Religiosity ,Social support ,Hurricane katrina ,Emergency Medicine ,Psychology ,Natural disaster ,Psychosocial ,General Nursing ,Demography - Abstract
This study examined how well the Posttraumatic Growth Inventory (PTGI; Tedeschi & Calhoun, 1996) corresponds with self-reported pre- to posttrauma changes in related constructs, including sense of purpose in life, religiosity, and social support. Participants were 328 low-income mothers (85.2% non-Hispanic Black) who survived Hurricane Katrina and completed surveys approximately 1 year predisaster (Time 1), 4 years postdisaster (Time 2), and 12 years postdisaster (Time 3). PTG was assessed at Time 2 and Time 3, and related constructs were assessed at all waves. Pre- to postdisaster changes in the following related constructs were significantly associated with the corresponding PTGI subscales: purpose in life with Relating to Others, Personal Strength, and New Possibilities; religiosity with Spiritual Change; and perceived social support with Relating to Others. The results demonstrate a link between a number of self-reported pre- to posttrauma psychological changes measured over time and the PTGI. Replication of these results using measures more closely aligned to the PTGI subscales, among more representative samples and in the aftermath of other traumatic events, is warranted.
- Published
- 2021
8. A Meta-analysis of the Effects of Mentoring on Youth in Foster Care
- Author
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Jean E. Rhodes, Kirsten M. Christensen, and Cyanea Y. S. Poon
- Subjects
education.field_of_study ,Social Psychology ,Salience (language) ,education ,Population ,Psychological intervention ,Moderation ,Education ,Developmental psychology ,Health psychology ,Foster care ,Meta-analysis ,Developmental and Educational Psychology ,Psychological abuse ,Psychology ,Social Sciences (miscellaneous) - Abstract
Research suggests that mentoring programs may promote a range of positive outcomes in youth populations. Less is known, however, about the extent to which such programs are effective in specialized youth populations, such as youth involved in the foster care system. The current study aimed to investigate the extent to which mentoring interventions promote positive outcomes among youth involved in the foster care system and to systematically explore factors that may moderate the effectiveness of mentoring interventions. Using a multilevel meta-analytic approach, this study estimated the effect size of nine formal mentoring programs in the United States serving youth involved with the foster care system (total n = 55,561). Analyses revealed a small-to-medium-sized overall effect (g = 0.342). Moderator analyses revealed weaker effects for studies containing higher proportions of youth with emotional abuse histories. Programs deploying near-peer mentors were more than twice as effective as intergenerational mentors. The findings highlight the salience of emotional abuse history, suggesting the utility of providing mentor trainings in trauma-informed care for this population.
- Published
- 2021
9. Associations between religious coping and long-term mental health in survivors of Hurricane Katrina
- Author
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Monica Arkin, Sarah R. Lowe, Cyanea Y. S. Poon, and Jean E. Rhodes
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Social Psychology ,Religious studies ,Applied Psychology - Published
- 2022
10. Risk and Resilience among Children with Incarcerated Parents: Examining Heterogeneity in Delinquency and School Outcomes
- Author
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Cherrelle L. Jones, Jean E. Rhodes, Rebecca L. Stelter, Matthew Hagler, Cyanea Y. S. Poon, Kathryn N. Stump, Kristen P. Kremer, and Janis B. Kupersmidt
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050103 clinical psychology ,Parent support ,Aggression ,Social connectedness ,05 social sciences ,Loneliness ,Social issues ,Risk and resilience ,Developmental and Educational Psychology ,medicine ,Juvenile delinquency ,0501 psychology and cognitive sciences ,medicine.symptom ,Life-span and Life-course Studies ,Psychology ,Depression (differential diagnoses) ,050104 developmental & child psychology ,Clinical psychology - Abstract
The present study utilized latent profile analysis with 1088 children with incarcerated parents to identify heterogeneity in behavioral and social problems. Four profiles were observed. The majority (61%) were well-adjusted with low behavioral problems at school and less affiliation with antisocial friends. Youth classified as overactive (20%) displayed frequent disruptive and hyperactive behaviors, while isolated youth (14%) exhibited high loneliness and depression and were most likely to be bullied. Youth in the aggressive profile (7%) exhibited frequent aggression, school behavioral problems, and affiliation with antisocial friends. Although the aggressive profile represented the smallest proportion of the sample, their level of delinquent behavior and number of negative school outcomes were the most concerning. Examination of risk and protective factors by profile found overactive and isolated youth to be more likely to have two or more adults in the household compared to well-adjusted and aggressive youth. Meanwhile, well-adjusted youth had significantly higher school connectedness, parent support, and positive teacher relationships. Aggressive youth were least likely to be raised by a married caregiver. Universal behavioral assessments of children with incarcerated parents would be useful in identifying youth at risk for escalating or persistent delinquency or hyperactivity.
- Published
- 2020
11. Be Still and You Will Know: A Mixed-Method Study on Solitude and Consideration of Future Consequences Among Youth in Rehabilitation
- Author
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Christian S. Chan, Cyanea Y. S. Poon, Pauline P. L. Chau, and Chun-Yin Chan
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Rehabilitation ,media_common.quotation_subject ,Qualitative interviews ,medicine.medical_treatment ,Therapeutic community ,Solitude ,Pathology and Forensic Medicine ,Developmental psychology ,Arts and Humanities (miscellaneous) ,Consideration of future consequences ,Intervention (counseling) ,Meaning-making ,medicine ,Moral responsibility ,Psychology ,Applied Psychology ,media_common - Abstract
Although solitude is found to be undesirable to many, systematic practice of it can yield positive psychological outcomes. This mixed-method study explored the process and influence of solitude as a behavioral intervention among youths in a therapeutic community in Hong Kong. Qualitative interviews with 43 youths (67.4% male, mean age = 18.3) revealed that solitude facilitated growth in their sense of personal responsibility, increased perspective-taking, increased respect for rules, change in life attitudes, and growth in consideration of future consequences. A two-wave prospective study ( n = 79, 82.3% male, mean age = 17.4) further demonstrated perceived meaningfulness in solitude predicted an increase in consideration of future consequences, but not in other types of behavioral intervention. This study preliminarily demonstrated solitude has beneficial outcomes among high-risk youths, and meaning-making can facilitate this relationship.
- Published
- 2021
12. Boredom begets boredom: An experience sampling study on the impact of teacher boredom on student boredom and motivation
- Author
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Victoria Ka-Ying Hui, Christy Y. F. Wong, Gigi Wing‐Chee Yuen, Cyanea Y. S. Poon, Vivian Wing Yan Kwong, Christian S. Chan, and Katy Y. Y. Tam
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Adult ,Male ,Experience sampling method ,Adolescent ,Ecological Momentary Assessment ,media_common.quotation_subject ,Education ,Developmental psychology ,Negatively associated ,Perception ,Developmental and Educational Psychology ,Complaint ,medicine ,Humans ,Learning ,0501 psychology and cognitive sciences ,Students ,media_common ,Motivation ,Multilevel modelling ,05 social sciences ,050301 education ,Boredom ,Learning motivation ,Social Perception ,Feeling ,Female ,School Teachers ,medicine.symptom ,Psychology ,0503 education ,050104 developmental & child psychology - Abstract
Background Boredom is a common complaint among students. Boredom was previously found to be negatively associated with academic outcomes, such as academic motivation, strategies, and achievement. It is of interest to understand students' in-class boredom, especially factors that might exacerbate it. Aims The current study examines the influence of teacher's boredom on students' in-class boredom and learning experience. It aims to understand the relationship between teacher boredom, students' perceived teacher boredom, student boredom, and student learning motivation. Sample A total of 437 students (54.8% female, MAge = 14.5 years, SD = 1.6) and 17 of their teachers (29.4% female, 76.5% 40 years old or below) participated in the study. Methods We conducted an experience sampling study, in which participants completed a 2-week diary. Data were analysed using multilevel modelling. Results and conclusions Results from multilevel modelling of 2,675 post-class evaluations indicated that teacher boredom was negatively associated with students' motivation. However, the relationship between teacher boredom and students' perceived teacher boredom was not significant, suggesting that students did not accurately perceive whether their teacher was bored. Results from indirect effect analysis further revealed that students' perception of teacher boredom predicted student learning motivation through student boredom. In other words, perceiving teachers being bored promoted students' own feeling of boredom, which in turn reduced their learning motivation. Together, these results indicate that when a teacher is bored in class, or when students perceive that their teacher is bored, students would have lower learning motivation.
- Published
- 2019
13. From helper to partner: Processes of contact in voluntarism with refugees in Chinese youths
- Author
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Cyanea Y S Poon
- Subjects
Adult ,Male ,Volunteers ,China ,Refugees ,Stereotyping ,030505 public health ,Social Psychology ,Refugee ,05 social sciences ,050109 social psychology ,Interviews as Topic ,Social group ,Young Adult ,03 medical and health sciences ,Hong Kong ,Humans ,Female ,Interpersonal Relations ,0501 psychology and cognitive sciences ,Voluntarism (action) ,0305 other medical science ,Psychology ,Social psychology ,Prejudice (legal term) - Abstract
Contact facilitates a reduction in prejudice and negative stereotypes between the social groups. The effect of such contact is optimized when there is equal status between groups, which in volunteerism is manifested through as mutually equitable partnership. This qualitative study examines the processes of contact through an intervention youth group that connects Chinese and refugee/asylum seeker youths in Hong Kong. Interviews were conducted with 5 participants (60% females; mean age = 24) in 2016. Results indicated the youth group facilitated contact within its members, where the more they engage, in frequency and intentionality, the more they find a sense of belonging with each other. Moreover, Chinese participants demonstrated a shift in seeing refugee participants as collaborators and friends instead of service-recipient. The findings shed light on the processes of contact within volunteerism and offers potential contribution of collaborative environment in similar integration intervention.
- Published
- 2019
14. Delayed gratification and psychosocial wellbeing among high-risk youth in rehabilitation: A latent change score analysis
- Author
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Kristen N. S. Tang, Christian S. Chan, and Cyanea Y. S. Poon
- Subjects
High-risk youth ,Change score ,Longitudinal study ,Rehabilitation ,Gratification ,medicine.medical_treatment ,05 social sciences ,050109 social psychology ,Delayed gratification ,Developmental and Educational Psychology ,medicine ,0501 psychology and cognitive sciences ,Life-span and Life-course Studies ,Psychology ,Psychosocial ,Applied Psychology ,050104 developmental & child psychology ,Clinical psychology - Abstract
This multiwave longitudinal study investigated the dynamic relationship between gratification delay and three facets of well-being among a group of high-risk youth in a residential therapeu...
- Published
- 2019
15. A well‐slept teacher is a better teacher: A multi‐respondent experience‐sampling study on sleep, stress, and emotional transmission in the classroom
- Author
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Victoria Ka-Ying Hui, Vivian Wing Yan Kwong, Gigi Wing‐Chee Yuen, Christian S. Chan, and Cyanea Y. S. Poon
- Subjects
Adult ,Male ,Experience sampling method ,Adolescent ,Ecological Momentary Assessment ,Emotions ,education ,Negative association ,Irritability ,behavioral disciplines and activities ,Developmental psychology ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,mental disorders ,medicine ,Humans ,Students ,Path analysis (statistics) ,General Psychology ,Motivation ,Sleep quality ,05 social sciences ,050301 education ,Poor sleep ,Respondent ,Hong Kong ,Female ,School Teachers ,medicine.symptom ,Sleep ,Psychology ,0503 education ,Stress, Psychological ,030217 neurology & neurosurgery - Abstract
The present study examined the impact of sleep, stress, and negative activating emotions of high-school teachers on their students' affective experience, academic motivation, and in-class satisfaction. It is hypothesized that teachers' sleep quality and stress have a positive influence on their own nervousness and irritability. With reference to the emotional crossover theory, teachers' nervousness and irritability are hypothesized to intensify students' nervousness and irritability and subsequently dampen their academic motivation and in-class satisfaction. Experience-sampling data were collected from 17 teachers and 437 students from two local high schools in Hong Kong across a 10-school-day period. Multilevel path analysis results revealed that teachers' stress was significantly associated with teachers' nervousness and irritability. Teachers' nervousness, rather than irritability, was subsequently associated with higher levels of nervousness and irritability among students, which, in turn, impaired their in-class satisfaction. There was also a significant negative association between students' irritability and their academic motivation. Results further showed that teachers' stress arising from poor sleep quality was a significant antecedent of the teacher-student emotional crossover, subsequently affecting students' academic motivation and in-class satisfaction. The findings highlight the detrimental effects of teachers' poor sleep and the resulting stress on students' academic and affective experience. Discussion focuses on how to improve teachers' sleep and manage their stress so as to enhance students' in-class emotions and academic motivation.
- Published
- 2019
16. A Meta-analysis of the Effects of Mentoring on Youth in Foster Care
- Author
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Cyanea Y S, Poon, Kirsten M, Christensen, and Jean E, Rhodes
- Subjects
Adolescent ,Mentors ,Humans ,Mentoring ,United States ,Foster Home Care - Abstract
Research suggests that mentoring programs may promote a range of positive outcomes in youth populations. Less is known, however, about the extent to which such programs are effective in specialized youth populations, such as youth involved in the foster care system. The current study aimed to investigate the extent to which mentoring interventions promote positive outcomes among youth involved in the foster care system and to systematically explore factors that may moderate the effectiveness of mentoring interventions. Using a multilevel meta-analytic approach, this study estimated the effect size of nine formal mentoring programs in the United States serving youth involved with the foster care system (total n = 55,561). Analyses revealed a small-to-medium-sized overall effect (g = 0.342). Moderator analyses revealed weaker effects for studies containing higher proportions of youth with emotional abuse histories. Programs deploying near-peer mentors were more than twice as effective as intergenerational mentors. The findings highlight the salience of emotional abuse history, suggesting the utility of providing mentor trainings in trauma-informed care for this population.
- Published
- 2021
17. Delayed school start time is associated with better sleep, daytime functioning, and life satisfaction in residential high‐school students ☆
- Author
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Cyanea Y. S. Poon, Christian S. Chan, Jacklyn C. Y. Leung, Kristy Nga Ting Lau, and Esther Yuet Ying Lau
- Subjects
Male ,Sleepiness ,Time Factors ,Adolescent ,Social Psychology ,education ,Personal Satisfaction ,Anxiety ,03 medical and health sciences ,0302 clinical medicine ,Sleep Initiation and Maintenance Disorders ,Developmental and Educational Psychology ,Insomnia ,medicine ,Humans ,Start time ,Longitudinal Studies ,030212 general & internal medicine ,Students ,Schools ,Sleep quality ,Depression ,Life satisfaction ,Psychological distress ,Sleep time ,Psychiatry and Mental health ,Pediatrics, Perinatology and Child Health ,Boarding school ,Hong Kong ,Sleep Deprivation ,Female ,Self Report ,Sleep (system call) ,medicine.symptom ,Sleep ,Psychology ,Stress, Psychological ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
The effects of a delayed school start time by one hour were examined at a boarding school in Hong Kong. Two cohorts of high school students (N = 228; 61.8% female) were recruited respectively before and after a school start time changed from 7:30am to 8:30am. Both cross-cohort and within-cohort longitudinal comparisons yielded significant increase in total sleep time. Cross-cohort comparison yielded improvement in sleep quality, insomnia, life satisfaction, and psychological distress. Longitudinal data suggested that the longer the additional sleep time, the better was sleep quality, day-time functioning, and subjective wellbeing.
- Published
- 2018
18. More than fun and games? Understanding the role of school-based mentor-mentee match activity profiles in relationship processes and outcomes
- Author
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Stella S. Kanchewa, Cyanea Y. S. Poon, McKenna F. Parnes, Kirsten M. Christensen, and Sarah E. O. Schwartz
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Longitudinal study ,Activity profile ,Sociology and Political Science ,education ,05 social sciences ,050301 education ,Education ,Developmental psychology ,Developmental and Educational Psychology ,0501 psychology and cognitive sciences ,School based ,Psychology ,School based intervention ,0503 education ,050104 developmental & child psychology - Abstract
This study investigated associations between mentor-mentee activities and relationship outcomes of school-based mentoring. Multigroup three-step latent profile analysis (LPA) assessed whether youth could be classified into distinct profiles based on their mentoring relationship activities, and whether these profiles were similar when taking into account youth academic success. Furthermore, regression analyses examined whether activity profile membership of mentored youth predicted youth relationship process outcomes. Participants (N = 1110) were drawn from a national, randomized longitudinal study of youth in Big Brothers Big Sisters School-Based Mentoring Programs. Multigroup LPA results indicated a two-profile model, labeled Balanced and Instructional based on varying engagement in mentoring activities. Descriptive analyses revealed no differences in youth, mentor, and program characteristics across groups. Controlling for these characteristics, mentees in the Balanced profile demonstrated more relational benefits than youth in the Instructional profile. Research and practice implications are discussed.
- Published
- 2021
19. Extrapulmonary involvement associated with Mycoplasma pneumoniae infection
- Author
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T Liong, K M Kwok, Y S Poon, K I Law, T L Lam, S Y Lam, K L Lee, and W F Ng
- Subjects
Erythema Multiforme ,Male ,Mycoplasma pneumoniae ,Fatal outcome ,Myocarditis ,Brain edema ,business.industry ,Brain Edema ,General Medicine ,Middle Aged ,medicine.disease ,medicine.disease_cause ,Serology ,Young Adult ,Fatal Outcome ,Lower respiratory tract infection ,Pneumonia, Mycoplasma ,Immunology ,medicine ,Humans ,Serologic Tests ,Erythema multiforme ,Young adult ,business - Abstract
Mycoplasma pneumoniae infection usually presents with upper and lower respiratory tract infection. Extrapulmonary involvement is not uncommon, however. We report two cases of predominantly extrapulmonary manifestations of Mycoplasma pneumoniae infection without significant pulmonary involvement. Both cases were diagnosed by serology. These cases illustrate the diversity of clinical presentations of Mycoplasma pneumoniae infection. Clinicians should maintain a high index of suspicion.
- Published
- 2015
20. Situational meaninglessness and state boredom:Cross-sectional and experience-sampling findings
- Author
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Christian S. Chan, Cyanea Y. S. Poon, Venus U. T. Wong, S. K. Cheung, Katy Y. Y. Tam, Eric Raymond Igou, and Wijnand A.P. van Tilburg
- Subjects
Experience sampling method ,Social Psychology ,existential psychology ,boredom proneness ,media_common.quotation_subject ,05 social sciences ,050109 social psychology ,Experimental and Cognitive Psychology ,meaning ,Boredom ,Moderation ,050105 experimental psychology ,Sadness ,experience sampling ,Perception ,medicine ,Personality ,0501 psychology and cognitive sciences ,state boredom ,Situational ethics ,medicine.symptom ,Big Five personality traits ,Psychology ,media_common ,Clinical psychology - Abstract
peer-reviewed Theories of boredom assert that boredom is a product of situational meaninglessness. We conducted two studies to test if the perceived meaningfulness of a situation is associated with state boredom, above and beyond sadness, personality traits, and boredom proneness. In Study 1, 105 participants (72.4% female: mean age = 33.9 years, SD = 17.5) described situations in which they experienced boredom, no boredom, engagement, or sadness. They then rated the level of state boredom, sadness, and meaninglessness that they experienced in that situation. As hypothesized, state boredom was associated with situational meaninglessness, before and after controlling for sadness. In Study 2, 148 participants (73.0% female; mean age = 19.2 years, SD = 1.8) first provided baseline data on personality traits and boredom proneness. Through a smartphone app-based experience-sampling method, they then responded to a brief questionnaire multiple times a day, across 7 days. The questionnaire asked about the nature of their current activity, whether the activity was done alone or with other people, and their affective state. Results from multilevel modelling of 3022 entries suggest that perceived meaningfulness of the activity was negatively associated with state boredom, above and beyond sadness, personality, and boredom proneness. We also found that being with others during the activity acted as a moderator; activities lower in perceived meaningfulness were associated with higher ratings of state boredom when done with others than when done alone. These results demonstrate that perceptions of meaninglessness characterize state boredom. ACCEPTED peer-reviewed
- Published
- 2018
21. Portomesenteric vein thrombosis following laparoscopic sleeve gastrectomy in a Chinese patient
- Author
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T Liong, S Y Lam, N K Chiu, H M Wong, K M Kwok, K L Lee, Y S Poon, and K I Law
- Subjects
Vein thrombosis ,medicine.medical_specialty ,Laparoscopic sleeve gastrectomy ,Venous thrombosis ,business.industry ,medicine.medical_treatment ,medicine ,Gastrectomy ,General Medicine ,business ,medicine.disease ,Surgery - Published
- 2017
22. Self-dual manifolds with symmetry
- Author
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C. LeBrun and Y. S. Poon
- Published
- 1993
23. The first novel influenza A (H1N1) fatality despite antiviral treatment and extracorporeal membrane oxygenation in Hong Kong
- Author
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T, Liong, K L, Lee, Y S, Poon, S Y, Lam, C P, Chan, C S, Yue, C M, Chu, K Y, Yuen, and K I, Law
- Subjects
Adult ,Extracorporeal Membrane Oxygenation ,Fatal Outcome ,Influenza A Virus, H1N1 Subtype ,Influenza, Human ,Hong Kong ,Humans ,Female ,Antiviral Agents ,Combined Modality Therapy - Abstract
We report the first fatality caused by novel influenza A (H1N1) infection despite having the diagnosis confirmed and being given antiviral treatment after hospitalisation. This patient was also the first with influenza A (H1N1) to be supported with extracorporeal membrane oxygenation in Hong Kong. Although extracorporeal membrane oxygenation is an effective means of supporting patients with refractory hypoxaemia on high mechanical ventilatory support, it is labour-intensive and technically demanding. We also discuss the challenges faced when managing this case.
- Published
- 2009
24. Ultrasensitive magnetic biosensor for homogeneous immunoassay
- Author
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Raymond C. Stevens, John Clarke, Robert McDermott, Y. S. Poon, Yann R. Chemla, H. L. Grossman, and M. D. Alper
- Subjects
Immunoassay ,Multidisciplinary ,Microscope ,Receptors, CCR5 ,Chemistry ,Immunomagnetic Separation ,Relaxation (NMR) ,Physics::Medical Physics ,Analytical chemistry ,Nanoparticle ,Biosensing Techniques ,Biological Sciences ,Sensitivity and Specificity ,Magnetic field ,law.invention ,SQUID ,Magnetization ,Magnetics ,law ,Calibration ,Liposomes ,Magnetic nanoparticles ,Humans ,Biosensor - Abstract
A technique is described for specific, sensitive, quantitative, and rapid detection of biological targets by using superparamagnetic nanoparticles and a “microscope” based on a high-transition temperature dc superconducting quantum interference device (SQUID). In this technique, a mylar film to which the targets have been bound is placed on the microscope. The film, at room temperature and atmospheric pressure, is typically 40 μm from the SQUID, which is at 77 K in a vacuum. A suspension of magnetic nanoparticles carrying antibodies directed against the target is added to the mixture in the well, and 1-s pulses of magnetic field are applied parallel to the SQUID. In the presence of this aligning field the nanoparticles develop a net magnetization, which relaxes when the field is turned off. Unbound nanoparticles relax rapidly by Brownian rotation and contribute no measurable signal. Nanoparticles that are bound to the target on the film are immobilized and undergo Néel relaxation, producing a slowly decaying magnetic flux, which is detected by the SQUID. The ability to distinguish between bound and unbound labels allows one to run homogeneous assays, which do not require separation and removal of unbound magnetic particles. The technique has been demonstrated with a model system of liposomes carrying the FLAG epitope. The SQUID microscope requires no more than (5 ± 2) × 10 4 magnetic nanoparticles to register a reproducible signal.
- Published
- 2000
25. Quaternionic Kähler 8-manifolds with positive scalar curvature
- Author
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Simon Salamon and Y. S. Poon
- Subjects
Positive current ,Algebra and Number Theory ,Mean curvature ,Prescribed scalar curvature problem ,Geometry and Topology ,Curvature ,Analysis ,Mathematics ,Mathematical physics ,Scalar curvature - Published
- 1991
26. DEFORMATION OF 2-STEP NILMANIFOLDS WITH ABELIAN COMPLEX STRUCTURES.
- Author
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C. MACLAUGHLIN, H. PEDERSEN, Y. S. POON, and S. SALAMON
- Abstract
We develop deformation theory for abelian invariant complex structures on a nilmanifold, and prove that in this case the invariance property is preserved by the Kuranishi process. A purely algebraic condition characterizes the deformations leading again to abelian structures, and we prove that such deformations are unobstructed. Various examples illustrate the resulting theory, and the behavior possible in three complex dimensions. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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