1. Effects of Primary Tumor Resection on Metastatic Breast Cancer Survival and the Predictive Power of Neutrophil: Lymphocyte Ratio on Prognosis
- Author
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Yaşar Çöpelci, Umut Rıza Gündüz, Bülent Dinç, Nurhan Haluk Belen, and Şeyda Gündüz
- Subjects
metastatic breast cancer ,primary tumor resection ,neutrophil-to-lymphocyte ratio ,survival ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 ,Medicine - Abstract
Objective:The aim was to investigate the effect of primary tumor resection (PTR) on survival in metastatic breast cancer patients and to assess the power of the neutrophil-to-lymphocyte ratio (NLR) regarding the prediction of prognosis in this patient group.Materials and Methods:Female patients diagnosed with and starting treatment for metastatic breast cancer from 2003 to 2016 in the general surgery and oncology clinics at a single center were retrospectively reviewed. Pre-treatment NLR value and survival situations were evaluated.Results:A total of 117 patients were enrolled. The disease-specific survival (DSS) of the patients was 41.4 months. When stratified into PTR and systemic treatment (ST) groups, there was no difference in the survival (p = 0.054); 43.5 months in the PTR group vs 30.7 months in the ST group. When hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative subgroups were analyzed, DSS was significantly longer (p = 0.02) in the PTR group (55.4 months) compared to the ST group (41.8 months). Finally, in patients with an NLR of
- Published
- 2021
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