1,607 results on '"Yaffe, Michael B"'
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2. Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis
3. The intrinsic substrate specificity of the human tyrosine kinome
4. Neutrophil-Mediated Inflammatory Plasminogen Degradation, Rather Than High Plasminogen-Activator Inhibitor-1, May Underly Failures and Inefficiencies of Intrapleural Fibrinolysis
5. Cell cycle dysregulation in cancer
6. An RNA damage response network mediates the lethality of 5-FU in colorectal cancer
7. BRCT domains as chromatin readers: Structure, function, and clinical implications
8. Contributors
9. An atlas of substrate specificities for the human serine/threonine kinome
10. Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition
11. The mission to ensure continued funding for excellent basic research
12. A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria
13. An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils
14. Study of Alteplase for Respiratory Failure in SARS-CoV-2 COVID-19: A Vanguard Multicenter, Rapidly Adaptive, Pragmatic, Randomized Controlled Trial
15. MUlticenter STudy of tissue plasminogen activator (alteplase) use in COVID‐19 severe respiratory failure (MUST COVID): A retrospective cohort study
16. Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks
17. Neutrophils, Inflammation, and Innate Immunity in Trauma-Induced Coagulopathy
18. Neutrophil heterogeneity and emergence of a distinct population of CD11b/CD18-activated low-density neutrophils after trauma
19. Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression
20. Study of alteplase for respiratory failure in severe acute respiratory syndrome coronavirus 2/COVID‐19: Study design of the phase IIa STARS trial
21. Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model
22. Fibrinolytic therapy for refractory COVID‐19 acute respiratory distress syndrome: Scientific rationale and review
23. Circulating Factors in Trauma Plasma Activate Specific Human Immune Cell Subsets
24. Abstract A035: Genome-wide CRISPRi screening reveals determinants of platinum sensitivity and resistance in high-grade serous ovarian cancer
25. Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion
26. The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks
27. Modern Management of Bleeding, Clotting, and Coagulopathy in Trauma Patients: What Is the Role of Viscoelastic Assays?
28. Clot activators do not expedite the time to predict massive transfusion in trauma patients analyzed with tissue plasminogen activator thrombelastography
29. VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
30. Atlas Drugged
31. Abstract IA015: Using systems approaches to interrogate DNA double strand break signaling and repair for optimal tumor cell killing
32. MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis
33. Neutrophils, Inflammation, and Innate Immunity in Trauma-Induced Coagulopathy
34. Organizing the Trauma Team in the Military and Civilian Settings
35. Hierarchical Organization Endows the Kinase Domain with Regulatory Plasticity
36. Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography
37. Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence*
38. The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.
39. Polo-like Kinase Cdc5 Controls the Local Activation of Rho1 to Promote Cytokinesis
40. A Systems Model of Signaling Identifies a Molecular Basis Set for Cytokine-Induced Apoptosis
41. TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation
42. PLASMINOGEN DEFICIENCY OF PLEURAL FLUID DUE TO NEUTROPHIL INFLAMMATORY PROTEASE DEGREDATION IN EMPYEMA PATIENTS: A CAUSE OF INTRAPLEURAL LYTIC FAILURE?
43. Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis
44. The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks
45. Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.
46. BRCT Repeats as Phosphopeptide-Binding Modules Involved in Protein Targeting
47. Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates
48. Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
49. 14-3-3 Transits to the Nucleus and Participates in Dynamic Nucleocytoplasmic Transport
50. BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage
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