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39 results on '"Yamashita, Masaaki"'

3. Photocatalytic Deuterium Atom Transfer Deuteration of Electron‐Deficient Alkenes with High Functional Group Tolerance.

Author

Suzuki, Akihiko, Kamei, Yuji, Yamashita, Masaaki, Seino, Yusuke, Yamaguchi, Yuto, Yoshino, Tatsuhiko, Kojima, Masahiro, and Matsunaga, Shigeki

Subjects
DEUTERATION, DEUTERIUM, ABSTRACTION reactions, FUNCTIONAL groups, CHEMOSELECTIVITY, ALKENES
Abstract

Due to its mild reaction conditions and unique chemoselectivity, hydrogen atom transfer (HAT) hydrogenation represents an indispensable method for the synthesis of complex molecules. Its analog using deuterium, deuterium atom transfer (DAT) deuteration, is expected to enable access to complex deuterium‐labeled compounds. However, DAT deuteration has been scarcely studied for synthetic purposes, and a method that possesses the favorable characteristics of HAT hydrogenations has remained elusive. Herein, we report a protocol for the photocatalytic DAT deuteration of electron‐deficient alkenes. In contrast to the previous DAT deuteration, this method tolerates a variety of synthetically useful functional groups including haloarenes. The late‐stage deuteration also allows access to deuterated amino acids as well as donepezil‐d2. Thus, this work demonstrates the potential of DAT chemistry to become the alternative method of choice for preparing deuterium‐containing molecules. [ABSTRACT FROM AUTHOR]

Published
2023
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4. Development of an artistic robot “Jumping Joe”

Author

Nassiraei, Amir A.F., Masakado, Seiji, Matsuo, Takayuki, Ichikawa, Kodai, Fukushima, Hajime, Murata, Masayuki, Sonoda, Takashi, Takahira, Isao, Yamashita, Masaaki, Sato, Masanori, Ishii, Kazuo, Miki, Tsutomu, Yagi, Tetsuya, Mayer, Norbert, and Ura, Tamaki

Published
2006
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16. Materia Japan

Author

Yamaji, Takafumi, primary, Matsuzaki, Akira, additional, Yamashita, Masaaki, additional, Majima, Yasuhiro, additional, and Ishikawa, Hiroshi, additional

Published
2003
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17. Recent Advance in Coated Steel Sheets

Author

ANDOH, Atsushi, primary, UCHIDA, Jun-ichi, additional, ENTANI, Hiroshi, additional, KATO, Chiaki, additional, KURODA, Hitoshi, additional, SATOU, Toshiki, additional, SHIMIZU, Masafumi, additional, FUJITA, Sakae, additional, MIYASAKA, Akihiro, additional, MORIMOTO, Yasuhide, additional, and YAMASHITA, Masaaki, additional

Published
2003
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39. Synthesis of Polysubstituted Enamides by Hydrogen Atom Transfer Alkene Isomerization Using Dual Cobalt/Photoredox Catalysis.

Author

Seino Y, Yamaguchi Y, Suzuki A, Yamashita M, Kamei Y, Kamiyama F, Yoshino T, Kojima M, and Matsunaga S

Abstract

M-HAT isomerization is a highly reliable method to access thermodynamically stable alkenes with high functional group tolerance. However, synthesis of heteroatom-substituted alkenes by M-HAT isomerization reaction is still underdeveloped. Herein, we report an enamide synthesis using M-HAT via a combination of cobalt and photoredox catalysis. This method tolerates a variety of functional groups including haloarenes, heteroarenes, free hydroxy groups, non-protected indoles, and drug derivatives. Furthermore, this method can isomerize styrene derivatives in good yield and E/Z selectivity., (© 2023 Wiley-VCH GmbH.)

Published
2023
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