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3. Enforce and selective operators of combinatorial games

Author

Abuku, Tomoaki, Kimura, Shun-ichi, Kiya, Hironori, Larsson, Urban, Saha, Indrajit, Suetsugu, Koki, and Yamashita, Takahiro

Subjects
Mathematics - Combinatorics
Abstract

We consider an {\em enforce operator} on impartial rulesets similar to the Muller Twist and the comply/constrain operator of Smith and St\u anic\u a, 2002. Applied to the rulesets A and B, on each turn the opponent enforces one of the rulesets and the current player complies, by playing a move in that ruleset. If the outcome table of the enforce variation of A and B is the same as the outcome table of A, then we say that A dominates B. We find necessary and sufficient conditions for this relation. Additionally, we define a {\em selective operator} and explore a distributive-lattice-like structure within applicable rulesets. Lastly, we define nim-values under enforce-rulesets, and establish that the Sprague-Grundy theory continues to hold, along with illustrative examples., Comment: 25 pages, 12 figures, 1 table more...

Published
2023

4. On variations of Yama Nim and Triangular Nim

Author

Kimura, Shun-ichi and Yamashita, Takahiro

Subjects
Mathematics - Combinatorics, 91A46
Abstract

Yama Nim is a two heaps Nim game introduced in the second author's Master Thesis, where the player takes more than $2$ tokens from one heap, and return $1$ token to the other heap. Triangular Nim is a generalization, where the player takes several tokens from one heap, and return some tokens (at least one token) to the other heap, so that the total number of the tokens in the heaps decrease strictly. In this paper, we investigate their winning strategies, Grundy numbers, and their variations and generalizations. Particularly interesting is the Wythoff variations, where in addition to the Yama/Triangular Nim moves, the player is allowed to take tokens from both heaps, say $i$ tokens from the first heap and $j$ tokens from the other, under some restrictions for $i$ and $j$. For example when we force $i=j>0$ for the Triangular Nim, then the pair of non-negative integers $(x, y)$ with $x$ less than or equal to $y$ is in the $P$-position if and only if $(x, y) is in {(0, 0), (0, 1), (1, 3), (3, 6), (6, 10), (10, 15), ...}$, namely the winning strategy is described by triangular numbers. In other rulesets, we also found examples where the square numbers, pentagonal numbers, geometric progressions, and so on., Comment: 20 pages more...

Published
2023

9. Early detection of necrosis in low-enhanced pancreatic parenchyma using contrast-enhanced computed tomography was a better predictor of clinical outcomes than pancreatic inflammation: A multicentric cohort study of severe acute pancreatitis

Author

Yamamoto, Tomonori, Horibe, Masayasu, Sanui, Masamitsu, Sasaki, Mitsuhito, Mizobata, Yasumitsu, Esaki, Maiko, Sawano, Hirotaka, Goto, Takashi, Ikeura, Tsukasa, Takeda, Tsuyoshi, Oda, Takuya, Yasuda, Hideto, Namiki, Shin, Miyazaki, Dai, Kitamura, Katsuya, Chiba, Nobutaka, Ozaki, Tetsu, Yamashita, Takahiro, Oshima, Taku, Hirota, Morihisa, Moriya, Takashi, Shirai, Kunihiro, Yamamoto, Satoshi, Kobayashi, Mioko, Saito, Koji, Saito, Shinjiro, Iwasaki, Eisuke, Kanai, Takanori, and Mayumi, Toshihiko more...

Published
2024
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13. Rhodopsin-mediated light-off-induced protein kinase A activation in mouse rod photoreceptor cells

Author

Sato, Shinya, Yamashita, Takahiro, and Matsuda, Michiyuki

Subjects
Biological Psychology, Biomedical and Clinical Sciences, Psychology, Neurosciences, Eye Disease and Disorders of Vision, Neurodegenerative, Aetiology, 2.1 Biological and endogenous factors, Animals, Cyclic AMP-Dependent Protein Kinases, Dopamine, Enzyme Activation, Mice, Transgenic, Microscopy, Fluorescence, Multiphoton, Retinal Rod Photoreceptor Cells, Rhodopsin, Transducin, retina, two-photon microscopy, FRET biosensor, protein kinase A, rhodopsin
Abstract

Light-induced extrasynaptic dopamine release in the retina reduces adenosine 3',5'-cyclic monophosphate (cAMP) in rod photoreceptor cells, which is thought to mediate light-dependent desensitization. However, the fine time course of the cAMP dynamics in rods remains elusive due to technical difficulty. Here, we visualized the spatiotemporal regulation of cAMP-dependent protein kinase (PKA) in mouse rods by two-photon live imaging of retinal explants of PKAchu mice, which express a fluorescent biosensor for PKA. Unexpectedly, in addition to the light-on-induced suppression, we observed prominent light-off-induced PKA activation. This activation required photopic light intensity and was confined to the illuminated rods. The estimated maximum spectral sensitivity of 489 nm and loss of the light-off-induced PKA activation in rod-transducin-knockout retinas strongly suggest the involvement of rhodopsin. In support of this notion, rhodopsin-deficient retinal explants showed only the light-on-induced PKA suppression. Taken together, these results suggest that, upon photopic light stimulation, rhodopsin and dopamine signals are integrated to shape the light-off-induced cAMP production and following PKA activation. This may support the dark adaptation of rods. more...

Published
2020

20. Dark noise and retinal degeneration from D190N-rhodopsin

Author

Silverman, Daniel, Chai, Zuying, Yue, Wendy W. S., Ramisetty, Sravani Keerthi, Lokappa, Sowmya Bekshe, Sakai, Kazumi, Frederiksen, Rikard, Bina, Parinaz, Tsang, Stephen H., Yamashita, Takahiro, Chen, Jeannie, and Yau, King-Wai more...

Published
2020

25. Validity of a Web-Based 24-Hour Dietary Recall of Energy and Nutrient Intakes in Japanese Adults.

Author

Nakadate, Misako, Kobayashi, Shunichiro, Ishihara, Junko, Takachi, Ribeka, Sugawara, Shiori, Hoshina, Yuchie, Kito, Kumiko, Kotemori, Ayaka, Maruya, Sachiko, Suzuki, Aoi, Obara, Taku, Ishikuro, Mami, Ueno, Fumihiko, Noda, Aoi, Aizawa, Misato, Takahashi, Ippei, Yonezawa, Yudai, Yamashita, Takahiro, Suzuki, Shigenori, and Murakami, Keiko more...

Abstract

Recently, web-based dietary assessment tools for the targeted population have been developed and used to estimate the dietary intake level in several epidemiological studies. This study aimed to examine the validity of estimating energy and nutrient intake by the web-based 24 h dietary recall (Web24HR), which we developed for the Japanese population. Overall, 228 adults aged ≥20 years who agreed to participate were included. Web24HR was administered three times per person: twice within 3 weeks and once 3 months later. The data on 3-day weighed food records (WFR) at 3-month intervals in the four seasons were collected using the reference method. The intake of energy and nutrients between Web24HR and WFR were compared using Pearson's correlation coefficients and the Bland–Altman analysis. As results, the correlations were moderate for both men (median r = 0.51) and women (median r = 0.38) except for iodine, retinol, retinol equivalents, and β-tocopherol. The Bland–Altman method revealed that the bias in intake was within ±10% for most nutrients, except for cholesterol, iodine, vitamin C, and the water content, in both sexes. Additionally, monounsaturated fatty acids in men and β-cryptoxanthin in women exhibited an underestimation of more than 10%. In conclusion, the Web24HR intake assessment showed moderate correlations for most nutrients in both sexes. The bias in intake was within ±10% for most nutrients, but there were discrepancies for some nutrients. This tool's performance is comparable to Japan's standard dietary exposure assessment methods and will be helpful for future applications in epidemiological studies, though caution is needed for certain nutrient assessments. [ABSTRACT FROM AUTHOR] more...

Published
2024
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28. The Effect of an Invasive Strategy for Treating Pancreatic Necrosis on Mortality: a Retrospective Multicenter Cohort Study

Author

Minami, Kazuhiro, Horibe, Masayasu, Sanui, Masamitsu, Sasaki, Mitsuhito, Iwasaki, Eisuke, Sawano, Hirotaka, Goto, Takashi, Ikeura, Tsukasa, Takeda, Tsuyoshi, Oda, Takuya, Yasuda, Hideto, Ogura, Yuki, Miyazaki, Dai, Kitamura, Katsuya, Chiba, Nobutaka, Ozaki, Tetsu, Yamashita, Takahiro, Koinuma, Toshitaka, Oshima, Taku, Yamamoto, Tomonori, Hirota, Morihisa, Tokuhira, Natsuko, Azumi, Yoshinori, Nagata, Keiji, Takeda, Kazunori, Furuya, Tomoki, Lefor, Alan Kawarai, Mayumi, Toshihiko, and Kanai, Takanori more...

Published
2020
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29. Etiology and mortality in severe acute pancreatitis: A multicenter study in Japan

Author

Yasuda, Hideto, Horibe, Masayasu, Sanui, Masamitsu, Sasaki, Mitsuhito, Suzuki, Naoya, Sawano, Hirotaka, Goto, Takashi, Ikeura, Tsukasa, Takeda, Tsuyoshi, Oda, Takuya, Ogura, Yuki, Miyazaki, Dai, Kitamura, Katsuya, Chiba, Nobutaka, Ozaki, Tetsu, Yamashita, Takahiro, Koinuma, Toshitaka, Oshima, Taku, Yamamoto, Tomonori, Hirota, Morihisa, Sato, Mizuki, Miyamoto, Kyohei, Mine, Tetsuya, Misumi, Takuyo, Takeda, Yuki, Iwasaki, Eisuke, Kanai, Takanori, and Mayumi, Toshihiko more...

Published
2020
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31. Functional diversification process of opsin genes for teleost visual and pineal photoreceptions

Author

50378535, Fujiyabu, Chihiro, Gyoja, Fuki, Sato, Keita, Kawano-Yamashita, Emi, Ohuchi, Hideyo, Kusakabe, Takehiro G., Yamashita, Takahiro, 50378535, Fujiyabu, Chihiro, Gyoja, Fuki, Sato, Keita, Kawano-Yamashita, Emi, Ohuchi, Hideyo, Kusakabe, Takehiro G., and Yamashita, Takahiro more...

Abstract

Most vertebrates have a rhodopsin gene with a five-exon structure for visual photoreception. By contrast, teleost fishes have an intron-less rhodopsin gene for visual photoreception and an intron-containing rhodopsin (exo-rhodopsin) gene for pineal photoreception. Here, our analysis of non-teleost and teleost fishes in various lineages of the Actinopterygii reveals that retroduplication after branching of the Polypteriformes produced the intron-less rhodopsin gene for visual photoreception, which converted the parental intron-containing rhodopsin gene into a pineal opsin in the common ancestor of the Teleostei. Additional analysis of a pineal opsin, pinopsin, shows that the pinopsin gene functions as a green-sensitive opsin together with the intron-containing rhodopsin gene for pineal photoreception in tarpon as an evolutionary intermediate state but is missing in other teleost fishes, probably because of the redundancy with the intron-containing rhodopsin gene. We propose an evolutionary scenario where unique retroduplication caused a “domino effect” on the functional diversification of teleost visual and pineal opsin genes. more...

Published
2024

33. Robot Path Planning by LSTM Network Under Changing Environment

Author

Inoue, Masaya, Yamashita, Takahiro, Nishida, Takeshi, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Bhatia, Sanjiv K., editor, Tiwari, Shailesh, editor, Mishra, Krishn K., editor, and Trivedi, Munesh C., editor more...

Published
2019
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38. Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy

Author

Suzumori, Nobuhiro, Sekizawa, Akihiko, Ebara, Takeshi, Samura, Osamu, Sasaki, Aiko, Akaishi, Rina, Wada, Seiji, Hamanoue, Haruka, Hirahara, Fumiki, Izumi, Haruna, Sawai, Hideaki, Nakamura, Hiroaki, Yamada, Takahiro, Miura, Kiyonori, Masuzaki, Hideaki, Yamashita, Takahiro, Okai, Takashi, Kamei, Yoshimasa, Namba, Akira, Murotsuki, Jun, Tanemoto, Tomohiro, Fukushima, Akimune, Haino, Kazufumi, Tairaku, Shinya, Matsubara, Keiichi, Maeda, Kazutoshi, Kaji, Takashi, Ogawa, Masanobu, Osada, Hisao, Nishizawa, Haruki, Okamoto, Yoko, Kanagawa, Takeshi, Kakigano, Aiko, Kitagawa, Michihiro, Ogawa, Masaki, Izumi, Shunichiro, Katagiri, Yukiko, Takeshita, Naoki, Kasai, Yasuyo, Naruse, Katsuhiko, Neki, Reiko, Masuyama, Hisashi, Hyodo, Maki, Kawano, Yukie, Ohba, Takashi, Ichizuka, Kiyotake, Nagamatsu, Takeshi, Watanabe, Atsushi, Shirato, Nahoko, Yotsumoto, Junko, Nishiyama, Miyuki, Hirose, Tatsuko, and Sago, Haruhiko more...

Published
2018
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44. Impact of Excessive Increase in Systolic Blood Pressure after Exercise on Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction

Author

Yamashita, Takahiro, primary, Sakakura, Kenichi, additional, Jinnouchi, Hiroyuki, additional, Taniguchi, Yousuke, additional, Tsukui, Takunori, additional, Hatori, Masashi, additional, Tamanaha, Yusuke, additional, Kasahara, Taku, additional, Watanabe, Yusuke, additional, Yamamoto, Kei, additional, Seguchi, Masaru, additional, and Fujita, Hideo, additional more...

Published
2023
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48. Serum brain natriuretic peptide levels may be a useful marker for early diagnosis of cardiomyopathy secondary to neuroblastoma: A case report.

Author

Fujiyama, Natsumi, Matsuo, Osamu, Yamashita, Takahiro, Kohrogi, Kensaku, Miyamura, Fumiya, Anan, Tadashi, and Nakamura, Kimitoshi

Subjects
BRAIN natriuretic factor, CARDIOMYOPATHIES, NEUROBLASTOMA, HEART failure, EARLY diagnosis, DILATED cardiomyopathy
Abstract

Key Clinical Message: Cardiomyopathy is a rare but serious complication associated with neuroblastoma. The brain natriuretic peptide level led to a diagnosis of secondary dilated cardiomyopathy before the worsening of heart failure symptoms. [ABSTRACT FROM AUTHOR] more...

Published
2024
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