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Coordinated Multipoint Processing (CoMP) is a promising method to improve cell edge data rate and system spectrum efficiency, which helps LTE-Advanced to meet the high data rate requirement of 4G mobile communication networks. In uplink, coordinated multipoint reception is transparent to user equipment, while significant gain can be achieved with coordination of multiple base stations. CoMP gain can be affected by network deployment, receiver algorithm, channel estimation accuracy and orthogonality of reference signals. In this article, we focuses on uplink CoMP reception in 3GPP long term evolution advanced (LTE-A). Deployment scenarios are introduced in both homogenous networks and heterogeneous networks. Evaluation are taken under system level simulation. Receiver schemes, realistic channel estimation, and impact of reference signals orthognality is taken into consideration. Performance improvement are shown and compared in different CoMP scenarios. [ABSTRACT FROM PUBLISHER]