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7 results on '"Yan, Zhijing"'

2. Estimating the aroma glycosides in flue-cured tobacco by solid-phase extraction and gas chromatography-mass spectrometry: changes in the bound aroma profile during leaf maturity

Author

Shun Zhou, Zhang Yaping, Kaibo Chen, She Shike, Chen Gang, Yan Zhijing, Dongfeng Guo, and He Qing

Subjects
chemistry.chemical_classification, Chromatography, biology, Chemistry, Glycoside, General Chemistry, biology.organism_classification, chemistry.chemical_compound, Polyphenol, Enzymatic hydrolysis, Curing of tobacco, Organic chemistry, Solid phase extraction, Gas chromatography–mass spectrometry, Derivatization, Aroma, Food Science
Abstract

Glycosidically bound aroma compounds in flue-cured tobacco were estimated by capillary gas chromatography–mass spectrometry (GC–MS). After a fast isolation of extracts obtained by HP-20 solid-phase extraction and methanol elution, glycosides were treated with enzymatic hydrolysis and trifluoroacetylation (TFA) before GC–MS analysis. A totall of 21 bound aglycones, mainly consisting of aliphatic alcohol, aromatic components, C13-norisoprenoids, sesquiterpenoids and polyphenols, were identified by enzymatic hydrolysis. In addition, with the aid of enzymatic hydrolysis, 14 glucosides, one rutinoside and three vicianosides were identified by TFA derivatization. The three vicianosides were identified for the first time in flue-cured tobacco. The norisoprenoids group made up >40% of the total level of aglycons in ripe tobacco, followed by polyphenol and aromatic derivatives (27 and 19%, respectively). Generally, levels of bound compounds increased significantly and the content of total glycosides increased by 36% with maturation. Among the glycosides detected, 3-oxo-α-ionol-glucoside was the most sensitive to maturity and increased the maximum degree. Copyright © 2015 John Wiley & Sons, Ltd.

Published
2015

3. The influence of γ-irradiation on the mechanical, thermal degradation, and flame retardant properties of EVA/LDPE/ATH blends

Author

Xiaofeng Wang, Yan Zhijing, Dongfeng Guo, Min Ning, She Shike, He Qing, Yuan Hu, Shun Zhou, and Zhang Yaping

Subjects
Thermogravimetric analysis, Materials science, Ethylene-vinyl acetate, Polyethylene, Condensed Matter Physics, chemistry.chemical_compound, Low-density polyethylene, chemistry, Thermal stability, Physical and Theoretical Chemistry, Composite material, Pyrolysis, Fire retardant, Flammability
Abstract

This work aimed to study the influence of γ-irradiation on the mechanical and thermal properties of flame retardant EVA/LDPE/ATH blends. Flame retardant poly(ethylene vinyl acetate)/low-density polyethylene/aluminum hydroxide (EVA/LDPE/ATH) blends were prepared, with a LOI value of 40 % and UL-94 V0 rating. The influence of different γ-irradiation levels on flammability as well as mechanical, electrical, and thermal properties of EVA/LDPE/ATH blends was investigated. The flame resistance of EVA/LDPE/ATH blends was found to be slightly improved after γ-irradiation, and meanwhile the mechanical, electrical, and thermal properties were all enhanced due to the increase of cross-linking density. Moreover, thermogravimetric analysis/infrared spectra (TG-IR) were used to explore the thermal degradation process of the EVA/LDPE blends. TG-IR results indicated that the thermal degradation of EVA/LDPE/ATH blends was delayed after γ-irradiation, and the reduced pyrolysis products amounts were responsible for the improved fire resistance and thermal stability.

Published
2014

7. Cost-effectiveness analysis of pharmaceutical care in adult critically ill patients: based on a prospective cohort study.

Author

Wei C, Hu M, Chen G, Yan Z, Yin W, and Wu Z

Abstract

Background: The medication regimen for critically ill patients is complex and dynamic, leading to a high incidence of drug-related problems. This study aimed to assess the effectiveness and economic efficiency of pharmaceutical care for these patients., Methods: In this prospective cohort study conducted in a tertiary hospital, adult patients were assigned either to a clinical pharmaceutical care group or a control group based on existing clinical grouping rules. Health outcomes and economic indicators were collected, followed by a cost-effectiveness analysis., Results: The acceptance rate for clinical pharmacist interventions was 89.31%. The pharmaceutical care group exhibited significant reductions in the rate of medication errors (40.65% vs. 61.69%, P < 0.001) and adverse drug events (44.52% vs. 56.45%, P = 0.020). The usage rates for special-grade antibiotics (85.16% vs. 91.13%, P = 0.009) and proton pump inhibitors (77.42% vs. 88.71%, P = 0.002) were also lower in the pharmaceutical care group. Secondary outcomes did not show significant differences in total hospital stay (21 days vs. 22 days, P = 0.092). However, ICU stay was significantly shorter (9 days vs. 11 days, P = 0.003) in the pharmaceutical care group. Cost-effectiveness analysis demonstrated that each 1% reduction in adverse drug events associated with ICU pharmaceutical care saved $226.75 in ICU hospitalization costs and $203.42 in total ICU drug costs. A 1% reduction in the medication error rate saved $128.57 in ICU hospitalization costs and $115.34 in total ICU drug costs., Conclusions: Pharmaceutical care significantly reduces adverse drug events and medication errors, promotes rational use of medications, decreases the length of ICU stay, and lowers treatment costs in critically ill patients, establishing a definitive advantage in terms of cost-effectiveness., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationship that could be construed as a potential conflict of interest., (Copyright © 2024 Wei, Hu, Chen, Yan, Yin and Wu.)

Published
2024
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