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Introduction: 1. Tuberous sclerosis complex (TSC) is a rare genetic disorder distinguished by noncancerous growths in different parts of the body, particularly in the brain, skin, kidneys, heart, and lungs. It is caused by mutations in either the TSC1 or TSC2 genes, which interfere with the mTOR pathway. The range of symptoms associated with TSC can vary greatly, from minor skin manifestations to serious neurological complications such as epilepsy, cognitive deficits, and autism spectrum disorders. Case Nuances: The case study details a 41-year-old woman who received a belated diagnosis of TSC. She had a history of seizures over the past 26 years, with a physical examination revealing classic TSC features such as facial angiofibroma, enamel pits, and periungual flbromas. The patient also had a background of learning difficulties and common neurological symptoms of TSC. Discussion: Treatment for TSC typically targets specific symptoms, with antiepileptic medications prescribed for seizures and surgical interventions for sizable tumors. Regular monitoring is essential to detect potential complications early on. Conclusion: The case emphasizes the significance of prompt diagnosis and comprehensive care in TSC to enhance patient outcomes and well-being. Given the disease's diverse nature, regular check-ups and tailored treatment strategies are vital for effective management. [ABSTRACT FROM AUTHOR]

Background: Medication reconciliation is the process of examining the patient's entire medication regimen at the time of admission, transfer, and discharge and comparing it with the regimen being considered for the new setting of care. This helps to prevent unintentional inconsistencies across transitions in medical care. Medication reconciliation protects patients from medication side effects while ensuring that they receive standard care. It serves as the baseline from which therapeutic interventions are developed, drug treatment is continued upon admission, and self-care is continued upon release. Objectives: Determining the frequency and kinds of discrepancies discovered during medication reconciliation was the main goal of this study. Determining the effect of medication reconciliation to assess the possible seriousness of medication inconsistencies and ascertain the drug's role in medication errors was the secondary goal. Methodology: In the inpatient units of a tertiary care hospital in the West Godavari District, a prospective, observational study on medication reconciliation was conducted for six months. Results: Of the 385 patients that made up this study, 224 (58.18%) were males and 161 (41.8%) were females. In 169 (43.89%) of the patients, medication discrepancies were detected. There were inconsistencies discovered at several transition points: 50 disparities were detected at admission, 50 during the transfer phase, and 17 on the discharge. Conclusion: A multi-centric assessment including parameters like the percentage of inpatients encountering at least one major medication error would be intriguing. This may support the idea that drug reconciliation is crucial for patient safety. [ABSTRACT FROM AUTHOR]

Background: Self-medication is the practice of treating any ailment or symptom that a person diagnoses for themselves without first visiting a physician. Different communities display different behaviours; hence the purpose of this study is to statistically investigate the patterns and prevalence of self-medication usage. Although health literacy practices have been increasingly recommended in public health literature, there is a lack of studies that examine the relationships between health literacy and self-medication. Methodology: A quantitative, descriptive, cross-sectional, community-based research approach was used in a sample of 316 participants. Health literacy was measured by Single Item Literacy Screener. Data was analysed using SPSS 29.0 version. Results: A total of 316 participants agreed to participate (63.9% were females). The results showed that more than half, 53.4% had adequate health literacy. The prevalence of self-medication was 74%, in these 52% had used medicines by previous prescription and 8% used alternative medicine. There was a significant relationship between the overall health literacy level and practice of self-medication. Conclusion: Improving the health literacy level of the public can reduce inappropriate self-medication Therefore, the design and implementation of training programs are necessary to increase the perception on the risk of self-medication. Appropriate reading skills are important for accessing health information, using health care services, and achieving desirable health outcomes. [ABSTRACT FROM AUTHOR]