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Early career academics (ECAs) are a highly vulnerable group, typically facing job insecurities, persistent pressure to publish, and conflicts in academic values and beliefs. Researchers have noted the precarious position of ECAs in neoliberal universities and expressed growing concerns regarding the effects of neoliberalism within higher education on ECAs' academic identity construction. To generate a comprehensive picture of ECAs' academic identity construction in neoliberal higher education, this paper reviewed existing studies (n = 17) on ECAs' identities from 2008 to 2022. A thematic synthesis revealed that ECAs' identities are fraught with insecurity and ambivalence but maintain a certain authenticity. In addition, it also found that ECAs use various identity construction strategies, including alignment, adherence, negotiation, and withdrawal. The paper also critically assessed the research methodologies utilized in ECAs' identity research and highlighted directions for future research. The review contributes to our understanding of the impact of neoliberalism on academic identity and ECAs' strategies for professional survival in a neoliberal context.

INTRODUCTION: Patients with acute uncomplicated appendicitis will be increasingly asked to choose between surgery and antibiotic management. We developed a novel decision aid for patients in the emergency department (ED) with acute appendicitis who are facing this choice. We describe the development of the decision aid and an initial feasibility study of its implementation in a busy tertiary care ED. MATERIALS AND METHODS: We conducted a prepost survey analysis comparing patients before and after standardized implementation of the decision aid. Patients were surveyed about their experience making treatment decisions after discharge from the hospital. The primary outcome measure was the total score on the decisional conflict scale (; 0-100; lower scores better). RESULTS: The study included 24 participants (12 in the predecision aid period; 12 in the post period). Only 33% of participants in each group knew antibiotics were a treatment option prior to arriving at the ED. Prior to implementing the use of decision aid, only 75% of patients reported being told antibiotics were a treatment option, while this increased to 100% after implementation of the decision aid. The mean total decisional conflict scalescores were similar in the pre and post periods (mean difference = 0.13, 95% CI: -13 - 13, P > 0.9). CONCLUSIONS: This novel appendicitis decision aid was effectively integrated into clinical practice and helped toinform patients about multiple treatment options. These data support further large-scale testing of the decision aid as part of standardized pathways for the management of patients with acute appendicitis.

Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in the United States with an estimated 476,000 cases per year. While historically, the long-term impact of Lyme disease on patients has been controversial, mounting evidence supports the idea that a substantial number of patients experience persistent symptoms following treatment. The research community has largely lacked the necessary funding to properly advance the scientific and clinical understanding of the disease, or to develop and evaluate innovative approaches for prevention, diagnosis, and treatment. Given the many outstanding questions raised into the diagnosis, clinical presentation and treatment of Lyme disease, and the underlying molecular mechanisms that trigger persistent disease, there is an urgent need for more support. This review article summarizes progress over the past 5 years in our understanding of Lyme and tick-borne diseases in the United States and highlights remaining challenges.

The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age-related diseases. Therefore, we investigated age-related changes to an important cellular regulator of inflammation, the macrophage, and the impact on fracture healing outcomes. We demonstrated that old mice (24 months) have delayed fracture healing with significantly less bone and more cartilage compared to young mice (3 months). The quantity of infiltrating macrophages into the fracture callus was similar in old and young mice. However, RNA-seq analysis demonstrated distinct differences in the transcriptomes of macrophages derived from the fracture callus of old and young mice, with an up-regulation of M1/pro-inflammatory genes in macrophages from old mice as well as dysregulation of other immune-related genes. Preventing infiltration of the fracture site by macrophages in old mice improved healing outcomes, with significantly more bone in the calluses of treated mice compared to age-matched controls. After preventing infiltration by macrophages, the macrophages remaining within the fracture callus were collected and examined via RNA-seq analysis, and their transcriptome resembled macrophages from young calluses. Taken together, infiltrating macrophages from old mice demonstrate detrimental age-related changes, and depleting infiltrating macrophages can improve fracture healing in old mice.

This paper reports on our inquiry into how language teachers' identities relate to their efforts to teach intercultural communicative competence. In the study, we collected data through in-depth interviews with and observations of 16 Chinese language teachers in Hong Kong's international schools. The analysis revealed that the participants simultaneously embraced multiple professional and sociocultural identities related to intercultural communicative competence teaching. Specifically, the professional identities included a Chinese language teacher identity and a school staff member identity, while the sociocultural identity comprised a Chinese culture bearer identity, a multicultural identity, a cultural transmitter identity, a culture learner identity, and a cultural bridge identity. These identities were found to compete with or reinforce each other in mediating the participants' efforts in relation to teaching intercultural communicative competence; different identities were often associated with different understandings of and approaches to teaching intercultural communicative competence. The findings suggest that language teacher educators need to recognise teacher identities as an important pedagogical resource when preparing language teachers for teaching in cross-cultural contexts.

The synergy between topology and non-Hermiticity in photonics holds immense potential for next-generation optical devices that are robust against defects. However, most demonstrations of non-Hermitian and topological photonics have been limited to super-wavelength scales due to increased radiative losses at the deep-subwavelength scale. By carefully designing radiative losses at the nanoscale, we demonstrate a non-Hermitian plasmonic–dielectric metasurface in the visible with non-trivial topology. The metasurface is based on a fourth order passive parity-time symmetric system. The designed device exhibits an exceptional concentric ring in its momentum space and is described by a Hamiltonian with a non-Hermitian Z3 ${\mathbb{Z}}_{3}$ topological invariant of V = −1. Fabricated devices are characterized using Fourier-space imaging for single-shot k-space measurements. Our results demonstrate a way to combine topology and non-Hermitian nanophotonics for designing robust devices with novel functionalities.

Domain walls separating regions of AB and BA interlayer stacking in bilayer graphene have attracted attention as novel examples of structural solitons, topological electronic boundaries, and nanoscale plasmonic scatterers. We show that strong coupling of domain walls to surface plasmons observed in infrared nanoimaging experiments is due to topological chiral modes confined to the walls. The optical transitions among these chiral modes and the band continua enhance the local conductivity, which leads to plasmon reflection by the domain walls. The imaging reveals two kinds of plasmonic standing-wave interference patterns, which we attribute to shear and tensile domain walls. We compute the electronic structure of both wall varieties and show that the tensile wall contains additional confined bands which produce a structure-specific contrast of the local conductivity, in agreement with the experiment. The coupling between the confined modes and the surface plasmon scattering unveiled in this work is expected to be common to other topological electronic boundaries found in van der Waals materials. This coupling provides a qualitatively new pathway toward controlling plasmons in nanostructures.

The purpose of this study is to examine preservice Chinese language teachers’ cognition in teaching intercultural communicative competence. In the study we collected data through in-depth interviews with seven preservice teachers in a Master of Education program (Teaching Chinese as a Second Language, TCSL) at a university in Hong Kong SAR, China. The findings indicated that the participants had a relatively positive attitude and inclination toward the development of students’ intercultural communicative competence, while their conceptualizations of culture tended to be static and ambiguous. In addition, the participants’ objectives in teaching intercultural communicative competence were found to be more attitude-than knowledge- or skill-oriented. The study offers valuable insights that preservice language teachers’ cognition plays a crucial role in their future professional development and calls for curricular innovations with intercultural aims in teacher education programs.

Duchenne muscular dystrophy (DMD) patients exhibit skeletal muscle weakness with continuous cycles of muscle fiber degeneration/regeneration, chronic inflammation, low bone mineral density, and increased risks of fracture. Fragility fractures and associated complications are considered as a consequence of the osteoporotic condition in these patients. Here, we aimed to establish the relationship between muscular dystrophy and fracture healing by assessing bone regeneration in mdx mice, a model of DMD with absence of osteoporosis. Our results illustrate that muscle defects in mdx mice impact the process of bone regeneration at various levels. In mdx fracture calluses, both cartilage and bone deposition were delayed followed by a delay in cartilage and bone remodeling. Vascularization of mdx fracture calluses was also decreased during the early stages of repair. Dystrophic muscles are known to contain elevated numbers of macrophages contributing to muscle degeneration. Accordingly, we observed increased macrophage recruitment in the mdx fracture calluses and abnormal macrophage accumulation throughout the process of bone regeneration. These changes in the inflammatory environment subsequently had an impact on the recruitment of osteoclasts and the remodeling phase of repair. Further damage to the mdx muscles, using a novel model of muscle trauma, amplified both the chronic inflammatory response and the delay in bone regeneration. In addition, PLX3397 treatment of mdx mice, a cFMS (colony stimulating factor receptor 1) inhibitor in monocytes, partially rescued the bone repair defect through increasing cartilage deposition and decreasing the number of macrophages. In conclusion, chronic inflammation in mdx mice contributes to the fracture healing delay and is associated with a decrease in angiogenesis and a transient delay in osteoclast recruitment. By revealing the role of dystrophic muscle in regulating the inflammatory response during bone repair, our results emphasize the implication of muscle in the normal bone repair process and may lead to improved treatment of fragility fractures in DMD patients.

This study addresses gaps in the existing literature on foreign language anxiety (FLA) by examining its impact on the oral proficiency of Chinese as a second language (CSL) learners. Unlike previous research, this investigation includes less commonly taught languages and considers the role of language contact as a mediating variable. Using structural equation modelling (SEM), we reveal that (1) CSL learning anxiety negatively affects CSL oral complexity and fluency in a direct way, but does not influence oral accuracy; (2) language contact affects CSL oral proficiency, with verbal contact having a particular impact on oral fluency; and (3) language contact does not mediate the relationship between CSL learning anxiety and oral proficiency. This study contributes to current theories of FLA in L2 acquisition by highlighting the roles of anxiety in different oral proficiency measurements even though the mediating effect of language contact does not exist. [ABSTRACT FROM AUTHOR]

Under the context of rapid development of the Internet of vehicles and vehicle-road collaboration system, active traffic management (ATM) becoming the mainstream means of road traffic control and developing toward refinement. In this paper, to study the high-precision lane-level dynamic induction control strategy in different scenarios, based on the NaSch model of cellular automata and combined with the characteristics of the failure section area, a fuzzy lane-changing bypass vehicle-following model considering lane-changing pressure in multi-lane failure scenarios was built. The simulation results show that (i) if the lane failure occurs on the middle lane, the lane should be induced in advance, and the induced lane change effect is the best at about 100 m. When the lane failure occurs in the left lane and right lane, the prompt is best at about 250 m. (ii) The induced distance should be based on actual traffic conditions, free combination of different early warning distances between 100 and 300 m can save about 20–30 s congestion time. (iii) The lane-level dynamic coordinated guidance control measures can effectively improve the road traffic efficiency compared with the static unified control measures, improve the traffic efficiency of road performance, and alleviate traffic congestion time. The conclusion of this paper can provide some reference for dynamic active control management and achieve higher accuracy of traffic flow lane-level control. [ABSTRACT FROM AUTHOR]

This study explores the direct and indirect effects of linguistic identification and learning motivation, specifically the L2 Motivational Self System (L2MSS), on Chinese oral proficiency, focusing on complexity, accuracy, and fluency (CAF). The participants were 203 Chinese as a Second Language (CSL) learners recruited from regions and countries participating in the Belt and Road Initiative. Structural equation models (SEMs) were employed to analyse the data. The results demonstrate that linguistic identification contributed to Chinese oral complexity directly, but showed weak or no direct influence on accuracy or fluency. Although learning motivation exerted a weak influence on Chinese oral accuracy, it mediated the path from linguistic identification to oral accuracy. Finally, it was found that linguistic identification significantly influenced learning motivation. This study contributes to the research on second language (L2) learning from a sociocultural perspective, and provides implications for CSL teaching and learning. [ABSTRACT FROM AUTHOR]