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2,875 results on '"Yang, Lian"'

8. Clinicopathological correlation of p40/TTF1 co-expression in NSCLC and review of related literature

Author

Yang, Lian, Xiao, Ming, Li, Xian, and Wang, Ya-lan

Subjects
Quantitative Biology - Tissues and Organs
Abstract

TTF1 and {\Delta}Np63/p40 have been used to differentiate ADC and SQC in hypofractionated NSCLC because of their sensitivity and specificity. There are few cases where TTF1 and {\Delta}Np63/p40 are expressed together in the same tumour cells, and little is known about the clinicopathological features, treatment and prognosis of such cases. We investigated the electron microscopic features, immunohistochemical expression and molecular variation of a case of TTF1/p40 co-expressing NSCLC and reviewed and summarised the relevant literature. Our patient was a 58-year-old male with a CT showing a left-sided lung occupancy. As in all other cases reported in the literature, the tumour showed a solid growth pattern with polygonal cells, eosinophilic cytoplasm and clearly visible nuclear fission. Immunohistochemistry showed positive for TTF-1, p40, CK5/6, CK7, P63 and p53, and negative for NapsinA and ALK. Electron microscopy showed tumour cells characterised by bidirectional differentiation of adenocytes and squamous cells, consistent with previous reports. Second-generation sequencing suggested co-mutation of STK11/LKB1 and NF1 genes in this case. Mutations in STK11/LKB1 and NF1 genes have been found in ADC and SQC and are often associated with drug resistance and poor prognosis, but STK11/NF1 co-mutation has not been reported and more cases are needed to reveal the association. p40/TTF1 co-expression in NSCLC may be an under-recognised variant of NSCLC The origin may be a double positive stem cell-like basal cell located in the distal airway, with rapid clinical progression and poor prognosis.

Published
2022

10. Research on work zone vehicle queuing behavior based on cellular automata

Author

Chen, Shao-Yuan, Zhong, Li-Xian, Zhu, Rui-Xi, Yang, Lian-Sheng, Aikebaier, Mirizhati, and Lin, Ci-Yun

Subjects
Nonlinear Sciences - Cellular Automata and Lattice Gases
Abstract

A model is proposed to estimate the work zone queue length, and the cellular automata based on empirical data is used for model validation. This estimation model can be applied to work zone organization and management to improve work zone capacity and security. Relationship between the average queue length and the warning zone length can be found, and the appropriate warning zone length can be determined according to design flow. Moreover, the appropriate work zone lane-changing strategies under different design flows are found through the estimation model.

Published
2022

11. Dynamic Clustering and Power Control for Two-Tier Wireless Federated Learning

Author

Guo, Wei, Huang, Chuan, Qin, Xiaoqi, Yang, Lian, and Zhang, Wei

Subjects
Computer Science - Information Theory, Electrical Engineering and Systems Science - Signal Processing
Abstract

Federated learning (FL) has been recognized as a promising distributed learning paradigm to support intelligent applications at the wireless edge, where a global model is trained iteratively through the collaboration of the edge devices without sharing their data. However, due to the relatively large communication cost between the devices and parameter server (PS), direct computing based on the information from the devices may not be resource efficient. This paper studies the joint communication and learning design for the over-the-air computation (AirComp)-based two-tier wireless FL scheme, where the lead devices first collect the local gradients from their nearby subordinate devices, and then send the merged results to the PS for the second round of aggregation. We establish a convergence result for the proposed scheme and derive the upper bound on the optimality gap between the expected and optimal global loss values. Next, based on the device distance and data importance, we propose a hierarchical clustering method to build the two-tier structure. Then, with only the instantaneous channel state information (CSI), we formulate the optimality gap minimization problem and solve it by using an efficient alternating minimization method. Numerical results show that the proposed scheme outperforms the baseline ones.

Published
2022

35. The Psychological Effects of Disasters on Children and Adolescents

Author

Du, Yi Zhan, Kao, Tsai Feng, Yang, Lian, Li, Chengchieh, Wang, Xintian, Striełkowski, Wadim, Editor-in-Chief, Black, Jessica M., Series Editor, Butterfield, Stephen A., Series Editor, Chang, Chi-Cheng, Series Editor, Cheng, Jiuqing, Series Editor, Dumanig, Francisco Perlas, Series Editor, Al-Mabuk, Radhi, Series Editor, Scheper-Hughes, Nancy, Series Editor, Urban, Mathias, Series Editor, Webb, Stephen, Series Editor, Hussain, Rosila Bee Binti Mohd, editor, Parc, Jimmyn, editor, and Li, Jia, editor

Published
2023
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