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2. Metabonomics Analysis of Brain Stem Tissue in Rats with Primary Brain Stem Injury Caused Death

Author

Qin SU, Qian-ling CHEN, Wei-bin WU, Qing-qing XIANG, Cheng-liang YANG, Dong-fang QIAO, Zhi-gang LI

Subjects
forensic pathology, metabonomics, cause of death, primary brain stem injury, liquid chromato-graphy-mass spectroscopy （lc-ms）, partial least square-discriminant analysis （pls-da）, random forest algorithm, rats, Medicine
Abstract

Objective To explore the potential biomarkers for the diagnosis of primary brain stem injury （PBSI） by using metabonomics method to observe the changes of metabolites in rats with PBSI caused death. Methods PBSI, non-brain stem brain injury and decapitation rat models were established, and metabolic maps of brain stem were obtained by LC-MS metabonomics method and annotated to the HMDB database. Partial least square-discriminant analysis （PLS-DA） and random forest methods were used to screen potential biomarkers associated with PBSI diagnosis. Results Eighty-six potential metabolic markers associated with PBSI were screened by PLS-DA. They were modeled and predicted by random forest algorithm with an accuracy rate of 83.3%. The 818 metabolic markers annotated to HMDB database were used for random forest modeling and prediction, and the accuracy rate was 88.9%. According to the importance in the identification of cause of death, the most important metabolic markers that were significantly up-regulated in PBSI group were HMDB0038126 （genipinic acid, GA）, HMDB0013272 （N-lauroylglycine）, HMDB0005199 [（R）-salsolinol] and HMDB0013645 （N,N-dimethylsphingosine）. Conclusion GA, N-lauroylglycine, （R）-salsolinol and N,N-dimethylsphingosine are expected to be important metabolite indicators in the diagnosis of PBSI caused death, thus providing clues for forensic medicine practice.

Published
2023
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3. Identification of Generic Task Types for Nuclear Power Plant Commissioning Tasks

Author

Liu, Zhao-Peng, Yin, Zi-Jian, Yang, Dong-Fang, Li, Zhi-Zhong, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Xu, Yang, editor, Sun, Yongbin, editor, Liu, Yanyang, editor, Gao, Feng, editor, Gu, Pengfei, editor, and Liu, Zheming, editor

Published
2022
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6. Standing seats for high-capacity trains

Author

Conor O’NEILL, Marcus WAKE, Lin FU, Christopher SAMUEL-HORSFALL, Evrim KOR, João VIEIRA, and Yang DONG FANG

Subjects
transport capacity, seating, standing seats, commuter, train interior, train design, Transportation engineering, TA1001-1280
Abstract

This paper details the design and potential implementation of standing seats in a commuter rail vehicle for the purposes of maximising capacity and revenue. The vehicle interior design is suited to the “Commuter Class” – a subset of travellers who travel primarily within the commuter belt and frequently utilise rail networks on a daily basis but require little additional space for luggage or peripherals. The concept delivers capacity increases in excess of 50% whilst still offering passengers a greater degree of personal space when compared with standing in aisles or gangways. The impact on vehicle stability and supporting intelligent systems are also discussed, delivering a unique design tailored specifically to meet the needs of the commuter class passenger.

Published
2014

7. Anatomy and microscopic observation of Ricinus communis seed structure

Author

Yang Dong-Fang, Xue-Min Guo, Xiao-Man Zhao, Ke Xu, Chen-Yu Zhang, and Xin-Rui Wang

Subjects
food.ingredient, Chemistry, food and beverages, Hilum (biology), Plant Science, Anatomy, Vascular bundle, Endosperm, food, medicine.anatomical_structure, Aleurone, Parenchyma, medicine, Radicle, Epidermis, Agronomy and Crop Science, Cotyledon, Biotechnology
Abstract

We systematically observed the structure and distribution of vascular bundles of castor ( Ricinus communis ) testa, endosperm and embryo with germination, separation, paraffin sectioning technique, and microscopic observation techniques, stained with safranine and fast green, along with schiff’s reagent, respectively. (1) Micropyle at the dorsal base of the seed was not covered by the caruncle. (2) The testa consisted of three parts: episperm, endopleura and the caruncle, in which the episperm was composed of the long columnar epidermal layer, sponge parenchma and palisade parenchma from outside to inside, while the endopleura was composed of Malpighian layer, sponge parenchma and the inner integument layer, with an air chamber surrounded by the inner layer and outer layer of endopleura at the end of the caruncle, similar to that of eggs. (3) Both the episperm and endopleura were distributed with vascular bundles, and the large ones of the episperm only distributed in the spongy parenchma of the ventral raphe of the seed, which extended from the hilum to the opposite end of the caruncle; while those of endopleura were also distributed in the spongy parenchtma, and they branched step by step through the bundle band, ending at the edge of the air chamber at the end of the caruncle; those of both the episperm and endopleura were continuous through the junction point of the chalazal end to form the vascular system of the testa. (4) The caruncle was composed of epidermis and parenchyma, in which parenchyma consisted of small parenchyma cells on the outside and large parenchyma cells on the inside. In the middle and ventral part of the caruncle, there were only two vascular bundles, which constituted the vascular system of the caruncle independently. In the caruncle, caruncle channel was also found, with the inner end opening in the air chamber of the endopleura and the outer end being blind. (5) No vascular bundles were found in the endosperm, which consisted of parenchymal cells containing a large number of aleurone grains. In the embryo, the vascular bundles were collateral, which differentiated in the hypocotyle and entered the main vein of two cotyledons from both sides of the top of the hypocotyle respectively, gradually reduced from 4 to 1 in the main veins, and the branches became thinner in the cotyledon, forming the vascular system of embryo. The cotyledon epidermis and mesophyll cells contained aleurone grains, but no aleurone grains were found in the plumule, hypocotyle and radicle. Two cotyledons separated from each other on the adaxial surface, while their abaxial surfaces were connected with the endosperm through the mucilaginous layers. The hypocotyle and radicle were spatially separated from the endosperm. These results provide an anatomical basis for comprehensively understanding the structure of the seeds and studying the seed development and germination and their material transportation.

Published
2020

18. Periodic DFT Study on High Pressure Behavior of Nitrogen-rich Energetic Crystal 4-Amino-3,7-Dinitrotriazolo-[5，1，c][1，2，4] Triazine.

Author

YANG Dong-fang, LI Hui-li, LIU Jin-jian, ZHAO Guo-zheng, and LU Ming

Subjects
DENSITY functional theory, NITROGEN, TRIAZINES, HYDROSTATIC pressure, ELECTRONIC structure
Abstract

Copyright of Chinese Journal of Explosives & Propellants is the property of Chinese Journal of Explosives & Propellants Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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19. Coast sea level and Asian monsoon system a downscaling exercise for Chinese coast

Author

Lian Shu-min, Cui Mao-chang, Eduardo Zorita, and Yang Dong-fang

Subjects
Oceanography, General Circulation Model, Climatology, Environmental science, East Asian Monsoon, Climate model, Present day, Scale (map), Sea level, System a, Water Science and Technology, Downscaling
Abstract

In this study, the authors examined the relationship between monthly sea level data and concurrent large-scale monthly mean sea level pressure and SST data for 1960 to 1990, which are reasonably well simulated by present day climate models; sea level variations due to variations of regional atmospheric forcing and oceanic circulation, are not adequately simulated by a global climate model because of insufficient spatial resolution. The authours applied a statistical “down scaling” strategy to sea level along the Chinese coast. Two interrelated processes were identified: one process is the local wind or wave set-up of water due to Asian monsoon wind anomalies; the other is the rainfall diluting effect in spring. At interdecadal time scale, the later becomes more important and most likely plays a major role in the planetary scale atmosphere-ocean interaction taking place in the eastern North Pacific.

Published
1998

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