18 results on '"Yankey KP"'
Search Results
2. Neuroschistosomiasis: A Case Report and Review of Literature.
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Yankey KP, Awoonor-William R, Owusu DN, Sackeyfio A, Nyarko V, Gross-Fenandez L, Addai F, Wulff I, and Boachie-Adjei O
- Abstract
Spinal cord involvement is a rare complication of the schistosomiasis manifesting as myeloradiculopathy, medullary or conus-cauda equina syndrome which can lead to potentially serious long-term disability. Computed tomography and magnetic resonance imaging coupled with biochemical parameters have become the mainstay of diagnosis. Biopsy which is the gold standard of diagnosis demonstrating the organism is usually reserved for cases of diagnostic challenge. We report a rare case of upper thoracic spinal cord schistosomiasis diagnosed by biopsy in an 18-year-old male migrant presenting to a spine and orthopaedic centre in Ghana with complaints of upper back pain and associated myeloradiculopathy symptoms. Initial suspicion of intramedullary cord tumour was made based on magnetic resonance imaging findings warranting biopsy which revealed schistosoma spp. He was treated with anthelminthics and corticosteroids with a resolution of symptoms., Competing Interests: The authors declare no conflicts of interest., (Copyright: © 2024 Journal of the West African College of Surgeons.)
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- 2024
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3. Medical complications and health-related quality of life in complex pediatric spine deformities exceeding 100 degrees or treated by 3CO.
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Yankey KP, Owusu DN, Sackeyfio A, Wulff I, Duah HO, Gross LF, Lenke LG, Sponseller P, Shah S, Erickson MA, Sides B, Newton P, Bumpass D, Gupta M, Ravinsky R, and Boachie-Adjei O
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- Humans, Child, Adolescent, Quality of Life, Retrospective Studies, Osteotomy adverse effects, Scoliosis surgery, Kyphosis surgery
- Abstract
Study Design: Retrospective review of prospectively collected data., Objective: To determine the incidence of medical complications in the pediatric population aged 10-20 years with baseline deformities exceeding 100 degrees or who had 3CO at surgery. Severe pediatric spine deformity poses a great challenge to the treating physician and carries a high complication rate. Pulmonary complications are among the most life threatening. The onus is on the treating surgeon to identify patients who are high risk and institute measures to mitigate the risk for successful outcomes., Method: Data of 251/311pts from FOX pediatric database from 17 international sites was queried for incidence of major medical complications. Comparative analysis was done to determine the impact of such complications on HRQoL using paired t-test. Risk factors associated with medical complications were assessed using Firth logistic regression., Results: 251/311pts had min 2 year f/u. 142F/109 M, average age 14.61years (10-20). Etiologies included 96 Cong,94 Idiopathic, 14-Post TB, 12-NM,12-NF,10-syndromic,8 others. Curve types included Scoliosis-121, Kyphoscoliosis 72, Kyphosis 58. Coronal and sag cobb avg 88° ± 41.47 and 91.92° ± 39.17, respectively. Deformity apices were in the thoracic region in 88% of patients. Pre-op co-morbidities included 54 (21.5%) cardiopulmonary; 7(2.79%) Genitounrinary;13 (5.18%) GI;13 (5.18%) Anxiety/depression; neurological 24 (9.56%). HGT was utilized in 103pts (41%) at an average duration of 68 days. Mean OR time was 459 min, blood loss averaged 1465 ml. VCR was performed in 120(47.81%), PSO in 16 pts (6.37%), SPO in 145pts (57.77%), Thoracoplasty in 132 pts (52.8%). 96% had blood and other blood products transfusion (FFP and platelets). There were 35 post-op medical complications occurring in 29pts (11.6%). Event-specific cumulative incidence was 24 (9.6%) pulmonary, 5(2.0%) gastrointestinal, 3(1.2%) cardiovascular, 1(0.4%) genitourinary and 1(0.4%) other complication. There was no mortality. Osteotomy grade was found to be an independent predictor of pulmonary complication. Despite significant improvement in baseline SRS total and Domain scores at 2 year FU irrespective of medical complication, the improvement in SRS scores were blunted in the complication group., Conclusion: Medical complications are common among pediatric patients undergoing complex spine surgery for severe deformity. However, medical complications can be managed successfully. Although baseline HRQoL improved irrespective of medical complication status, clinical differences in the magnitude of the changes in HRQoL were observed in some domains., (© 2023. The Author(s), under exclusive licence to Scoliosis Research Society.)
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- 2023
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4. The Effect of Prolonged Pre-Operative Halo Gravity Traction for Severe Spinal Deformities on the Cervical Spine Radiographs.
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Yankey KP, Duah HO, Sacramento-Domínguez C, Tutu HO, Owiredu MA, Mahmud R, Wulff I, Ofori-Amankwah G, Akoto H, and Boachie-Adjei O
- Abstract
Study Design: Retrospective review of consecutive series., Objective: The study sought to assess the effect of prolonged pre-operative halo gravity traction (HGT) on the c-spine radiographs., Methods: Data of 37 pediatric and adult patients who underwent ≥ 12wks pre-op HGT prior to definitive spine surgery from 2013-2015 at a single site in West Africa was reviewed. Radiographic assessment of the c-spine including ADI, SVA and C2-C7 Lordosis were done at pre HGT and at 4 weekly intervals. Paired T-Test was performed to evaluate changes in these parameters during HGT., Results: 37pts, 18/19 (F/M). Average age 18.2yrs. Diagnoses: 22 idiopathic, 6 congenital, 3 Post TB, 2 NM and 4 NF. Average duration of HGT: 125 days. Baseline coronal Cobb:130 deg, corrected 30% in HGT; baseline sagittal Cobb:146 deg, corrected 32% post HGT. Baseline ADI (3.17 ± 0.63 mm) did not change at 4wks ( P > 0.05) but reduced at 8wks (2.80 ± 0.56 mm) and 12wks (2.67 ± 0.51 mm) post HGT ( P < 0.05). Baseline HGT SVA (20.7 ± 14.98 mm) significantly improved at 4wks (11.55 ± 10.26 mm), 8wks (7.54 ± 6.78 mm) and 12wks (8.88 ± 4.5 mm) ( P < 0.05). Baseline C2-C7 lordosis (43 ± 20.1 deg) reduced at 4wks (26 ± 16.37 deg), 8wks (17.8 ± 14.77 deg) and 12wks (16.7 ± 11.33 deg) post HGT ( P < 0.05). There was no incidence of atlanto-axial instability on flexion extension radiographs at any interval., Conclusion: Prolonged HGT, while providing partial correction of severe spine deformities, also appeared to have no adverse effect on atlanto-axial stability or cervical alignment. Therefore, HGT can be safely applied for several weeks in the preoperative management of severe spine deformities in pediatric/adult patients.
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- 2023
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5. SPINE20 recommendations 2021: spine care for people's health and prosperity.
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Costanzo G, Misaggi B, Ricciardi L, AlEissa SI, Tamai K, Alhelal F, Alqahtani Y, Alsobayel HI, Arand M, Balsano M, Blattert TR, Brayda-Bruno M, Busari JO, Campello M, Chhabra HS, Tamburrelli FC, Côté P, Darwono B, Kandziora F, La Maida GA, Muehlbauer EJ, Mulukutla RD, Pereira P, Rajasekaran S, Rothenfluh DA, Sullivan WJ, Truumees E, Dohring EJ, Pigott T, Shetty AP, Teli MGA, Wang JC, Ames C, Anema JR, Bang A, Cheung KMC, Gross DP, Haldeman S, Minisola S, Mullerpatan R, Negrini S, Salmi LR, Spinelli MS, Vlok A, Yankey KP, Zaina F, Alturkistany A, Franke J, Liljenqvist UR, Piccirillo M, and Nordin M
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- Aged, Humans, Italy, Pandemics prevention & control, COVID-19, Spinal Diseases therapy
- Abstract
Purpose: The focus of SPINE20 is to develop evidence-based policy recommendations for the G20 countries to work with governments to reduce the burden of spine disease, and disability., Methods: On September 17-18, 2021, SPINE20 held its annual meeting in Rome, Italy. Prior to the meeting, the SPINE20 created six proposed recommendations. These recommendations were uploaded to the SPINE20 website 10 days before the meeting and opened to the public for comments. The recommendations were discussed at the meeting allowing the participants to object and provide comments., Results: In total, 27 societies endorsed the following recommendations. SPINE20 calls upon the G20 countries: (1) to expand telehealth for the access to spine care, especially in light of the current situation with COVID-19. (2) To adopt value-based interprofessional spine care as an approach to improve patient outcomes and reduce disability. (3) To facilitate access and invest in the development of a competent rehabilitation workforce to reduce the burden of disability related to spine disorders. (4) To adopt a strategy to promote daily physical activity and exercises among the elderly population to maintain an active and independent life with a healthy spine, particularly after COVID-19 pandemic. (5) To engage in capacity building with emerging countries and underserved communities for the benefit of spine patients. (6) To promote strategies to transfer evidence-based advances into patient benefit through effective implementation processes., Conclusions: SPINE20's initiatives will make governments and decision makers aware of efforts to reduce needless suffering from disabling spine pain through education that can be instituted across the globe., (© 2022. The Author(s).)
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- 2022
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6. Surgical outcomes of severe spinal deformities exceeding 100° or treated by vertebral column resection (VCR). Does implant density matter?: an observational study of deformity groupings.
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Boachie-Adjei O, Duah HO, Sackeyfio A, Yankey KP, Lenke LG, Sponseller PD, Samdani AF, Sucato DJ, Sides BA, Newton PO, Shah SA, Akoto H, and Gupta MC
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- Child, Humans, Osteotomy methods, Postoperative Complications etiology, Prospective Studies, Retrospective Studies, Spine abnormalities, Spine surgery, Treatment Outcome, Scoliosis surgery
- Abstract
Study Design: Prospective multicenter international observational study., Objective: To investigate the effect of implant density on clinical outcomes in complex pediatric spine reconstruction. Implant density in spine deformity surgery has been a subject of much debate with some authors advocating higher density for better correction. Few studies have looked at the effect of implant density on severe curves > 100 deg or treated with vertebral column resection (VCR)., Methods: 250/311 pts with 2-year f/u enrolled in the FOX pediatric database from 17 international sites were queried for the impact of implant density and surgical outcomes. Patients were grouped into three implant density categories for comparative analysis Group 1 (density ≤ 1), Group 2 (1 < density < 1.5) and Group 3 (density; 1.5-2)., Results: 250 pts: 47 (Grp1)/99 (Grp2) /104 (Grp3); Pre-op age and etiology and curve types were similar in all groups, but body mass index (BMI) was higher in Grp3. Grps 1 and 2 had significantly higher sagittal deformity angular ratio (S-DAR) compared to Grp 3 (p < 0.001). Pre-op Halo Gravity Traction (HGT) was used in 55.3%/44.4%/31.7%, p = 0.017; Grp1/Grp2/Grp3, respectively. Average duration of surgery (min) was higher in Grp3 relative to Grp1 only: 352.5/456.5/515.0, p = 0.0029. Blood loss was similar in all Grps. Rate of VCR, PSO and SPO was similar in all Grps. Pre-op Coronal Cobb avg 96.1/83.6/88.6, p = 0.2342, attained similar correction after HGT (24.6%/27.2%/23.2%, p = 0.4864. Coronal Cobb corrections at 2-year follow-up (FU) were (37.1%/40.3%/53.5%, p = 0.0004). Pre-op sagittal Cobb was (105.4/101.9/75.9, p < 0.01.), achieved similar %correction in HGT (19.1%/22.3%/22.5%, p = 0.6851) and at 2-year FU (39.6%/41.4%/29.8%, p = 0.1916). After adjusting for C-DAR, S-DAR, pre-op coronal and sagittal Cobb, etiology, curve types, age, BMI and number of rods in multivariate analysis, the odds of developing post-operative implant complication was 11 times greater in group 1 compared to group 3 (OR = 11.17,95% CI 2.34-53.32). There was significant improvement in SRS scores in all Grps at 2-year FU., Conclusion: Although higher implant density was observed to be associated with greater curve correction and lower rates of post-operative implant-related complication and revision in heterogeneous case groups, the results may not imply causality of implant density on the outcomes in severe pediatric spine reconstruction., (© 2022. The Author(s), under exclusive licence to Scoliosis Research Society.)
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- 2022
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7. Postoperative Pulmonary Complications in Complex Pediatric and Adult Spine Deformity: A Retrospective Review of Consecutive Patients Treated at a Single Site in West Africa.
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Wulff I, Duah HO, Osei Tutu H, Ofori-Amankwah G, Yankey KP, Owiredu MA, Bidemi Yahaya H, Akoto H, Oteng-Yeboah A, and Boachie-Adjei O
- Abstract
Study Design: Retrospective review of consecutive series., Objectives: This study sought to assess the incidence, risk factors, and outcomes of pulmonary complication following complex spine deformity surgery in a low-resourced setting in West Africa., Methods: Data of 276 complex spine deformity patients aged 3 to 25 years who were treated consecutively was retrospectively reviewed. Patients were categorized into 2 groups during data analysis based on pulmonary complication status: group 1: yes versus group 2: no. Comparative descriptive and inferential analysis were performed to compare the 2 groups., Results: The incidence of pulmonary complication was 17/276 (6.1%) in group 1. A total of 259 patients had no events (group 2). There were 8 males and 9 females in group 1 versus 100 males and 159 females in group 2. Body mass index was similar in both groups (17.2 vs 18.4 kg/m
2 , P = .15). Average values (group 1 vs group 2, respectively) were as follows: preoperative sagittal Cobb angle (90.6° vs 88.7°, P = .87.), coronal Cobb angle (95° vs 88.5°, P = .43), preoperative forced vital capacity (45.3% vs 62.0%, P = .02), preoperative FEV1 (forced expiratory volume in 1 second) (41.9% vs 63.1%, P < .001). Estimated blood loss, operating room time, and surgery levels were similar in both groups. Thoracoplasty and spinal osteotomies were performed at similar rates in both groups, except for Smith-Peterson osteotomy. Multivariate logistic regression showed that every unit increase in preoperative FEV1 (%) decreases the odds of pulmonary complication by 9% (OR = 0.91, 95% CI 0.84-0.98, P = .013)., Conclusion: The observed 6.1% incidence of pulmonary complications is comparable to reported series. Preoperative FEV1 was an independent predictor of pulmonary complications. The observed case fatality rate following pulmonary complications (17%) highlights the complexity of cases in underserved regions and the need for thorough preoperative evaluation to identify high-risk patients.- Published
- 2021
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8. One-stage multiple posterior column osteotomies and fusion and pre-op halo-gravity traction may result in a comparative and safer correction of complex spine deformity than vertebral column resection.
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Sacramento-Domínguez C, Cynthia N, Yankey KP, Tutu HO, Wulff I, Akoto H, and Boachie-Adjei O
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- Adolescent, Female, Humans, Male, Osteotomy, Retrospective Studies, Spine diagnostic imaging, Spine surgery, Treatment Outcome, Young Adult, Scoliosis diagnostic imaging, Scoliosis surgery, Traction
- Abstract
Study Design: A retrospective review of prospectively collected from patients recruited at a single center., Purpose: To test whether safe and optimal correction can be obtained with preoperative halo-gravity traction and posterior spinal fusion with adjunctive procedures but without VCR. Posterior vertebral column resection(VCR) is gaining popularity for correction of severe spinal deformity. However, it is a highly technically demanding procedure with potential risk for complications and neurological injury., Methods: In total, 72 patients with severe spinal deformity (Cobb angle > 100º) who underwent HGT followed by definitive PSF with PCO, with or without concave rib osteotomy and thoracoplasty. Demographic and surgical data were collected. Conventional coronal and sagittal radiographic measurements were obtained pre-traction, post-traction, post-op and at follow-up to determine the final deformity correction. Postoperative neurological and major complications were reviewed. We used Chi-square to compare proportion between groups and t test to compare groups in quantitative/ordinal variables., Results: There were 72 patients (35 females, 37 males). The etiology was congenital (21),idiopathic (45), neurofibromatosis (2) and neuromuscular (4). The mean was: age 18 ± 4.6 years; duration of HGT 103 ± 35 days; coronal Cobb angle before traction 131.5 ± 21.4º vs 92. ± 15.9º after HGT (30% correction) and 72.8 ± 12.7º after fusion (47% correction); kyphosis angle before traction 134.7 ± 32.3º vs 97.1 ± 22.4º after HGT and 73.7 ± 21.3º post-fusion. Number of fusion levels 14 ± 1; EBL 1730 ± 744 cc; number of PCOs done 5 ± 2; number of concave rib osteotomies (2 ± 2). There were 16 patients with postoperative complications (22.2%), 10 medical, one wound infection, 2 implant related and 3 post-op neuro-deficits (all of whom recovered at follow-up). There was one death (cardiac arrest)., Conclusion: HGT and one-stage posterior fusion with PCO, with or without concave rib resection and thoracoplasty, without VCR, achieved satisfactory correction of rigid complex spine deformity with minimal neurological complications. The results compare favorably with previous reports of similar deformities treated with VCR., Level of Evidence: III., (© 2021. Scoliosis Research Society.)
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- 2021
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9. Surgical management of complex post-tuberculous kyphosis among African patients: clinical and radiographic outcomes for a consecutive series treated at a single institution in West Africa.
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Maziad AM, Adogwa O, Duah HO, Yankey KP, Owusu DN, Sackeyfio A, Owiredu MA, Wilps T, Ofori-Amankwah G, Coleman F, Akoto H, Wulff I, and Boachie-Adjei O
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- Adult, Humans, Retrospective Studies, Treatment Outcome, Young Adult, Kyphosis diagnostic imaging, Kyphosis etiology, Kyphosis surgery, Scoliosis, Tuberculosis, Spinal complications, Tuberculosis, Spinal diagnostic imaging, Tuberculosis, Spinal surgery
- Abstract
Study Design: Retrospective review of consecutive series., Objective: To assess the clinical and radiographic outcomes after surgical management of post-tuberculous kyphosis. Post-tuberculous (TB) kyphosis can lead to progressive pulmonary and neurological deterioration. Surgery is indicated to decompress neural elements and correct the spine deformity. Although posterior vertebral column resection (PVCR) has been established as the treatment of choice for severe TB kyphosis, there is paucity of studies on the clinical outcomes among patients treated in West Africa., Methods: Clinical and radiographic data of 57 patients (pts) who underwent surgical correction of post-TB kyphosis at a single site in West Africa between 2013 and 2018 (≥ 2-year follow-up in 36 pts, ≥ 1-year FU in 21 pts). Pre- and post-op SRS scores and radiographic outcomes were compared using Paired t test., Results: 57 patients, 36M:21F. Mean age 19 (11-57 years). 22/57 pts (39.3%) underwent pre-op halo gravity traction (HGT) for an average duration of 86 days (8-144 days). HGT pts had a higher baseline regional kyphosis (125.1 ± 20.9) compared to non-HGT pts (64.6 ± 31.8, p < 0.001). Post-HGT regional kyphosis corrected to 101.2 ± 23 (24° correction). 53 pts (92.9%) underwent posterior-only surgery and 4 (7.0%) combined anterior-posterior surgery. 39 (68.4%) had PVCR, 11 (19.3%) PSO, and 16 (28.1%) thoracoplasty. Intraoperative neuromonitoring (IOM) signal changes occurred in 23/57 pts (≈ 40%), dural tear in 5 pts (8.8%), pleural tear in 3 pts (5.3%), ureteric injury in 1 pt (1.7%), and vascular injury in 1 pt (1.7%). Post-op complications included four (7.0%) infection, three (5.3%) implant related, two (3.5%) radiographic (one PJK and one DJK), one (1.7%) neurologic, one (1.7%) wound problem, and two (3.5%) sacral ulcers. IOM changes were similar in the VCR (48.7%) and non-VCR (23.5%) pts, p > 0.05. Complication rates were similar among HGT and non-HGT groups. Significant improvements from baseline were seen in the average SRS Total and domains scores and radiographic measurements for patients who attained 2-year follow-up., Conclusion: PVCR ± HGT can provide safe and optimal correction in cases of severe post-TB kyphosis with good clinical and radiographic outcomes in underserved regions.
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- 2021
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10. New neurologic deficit and recovery rates in the treatment of complex pediatric spine deformities exceeding 100 degrees or treated by vertebral column resection (VCR).
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Boachie-Adjei O, Duah HO, Yankey KP, Lenke LG, Sponseller PD, Sucato DJ, Samdani AF, Newton PO, Shah SA, Erickson MA, Akoto H, Sides BA, and Gupta MC
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- Adolescent, Adult, Child, Female, Humans, Male, Prospective Studies, Retrospective Studies, Spine surgery, United States, Kyphosis surgery, Postoperative Complications epidemiology, Postoperative Complications etiology
- Abstract
Study Design: Prospective multicenter international observational study., Objective: To investigate incidence of new neurologic deficit (NND) and the long-term recovery patterns following complex pediatric spine deformity surgery. The SRS M&M reports identify pediatric patients as having higher rate of new neurologic deficit compared with adults, while congenital and neuromuscular deformities are associated with higher new neurologic risks. Very few studies have had the large numbers of pediatric patients with curves exceeding 100 deg to ascertain the new neurologic deficit (NND) rates and recovery patterns as it relates to curve laterality and diagnosis., Method: The FOX pediatric database from 17 international sites was queried for New Neurologic Deficit (NND) as characterized by change in American Spinal Injury Association (ASIA) Lower or Upper Extremity Motor Score. Recovery rates at specific intervals were recorded and related to the curve type and etiology., Results: Data of 286 consecutive patients with normal pre-operative neurologic exams were reviewed. There were 160 females vs 125 males with an average age of 14.6 years. NND occurred in 27 patients (9.4%) in the immediate post-operative period. Diagnostic categories included idiopathic scoliosis (3 patients); idiopathic kyphoscoliosis(5 patients); congenital scoliosis (7 patients); congenital kyphoscoliosis (4 patients); congenital kyphosis (6 patients), other kyphosis (1 patient) and syndromic (1 patient). 1 patient was lost to follow-up (f/u) after discharge; 1 had chronic deficits at the first post-operative erect visit (from discharge to 9 months f/u) and was subsequently lost to follow-up; 2 patients were improving at 1-year f/u but lost to subsequent f/u. 16 patients had normal neurologic function by the time of the first post-operative erect visit, 21 patients at 1-year f/u and 21 patients at the 2-year f/u. 2 patients (0.69%) had improved NND at 2-year mark., Conclusion: A significant proportion of patients with complex spine deformity experience NND. However, significant improvement in neurologic function can be expected over time as seen in this study without additional surgical intervention in most cases. Congenital deformities accounted for 63% of the patients experiencing NND.
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- 2021
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11. Characterization of complex vertebral transposition (gamma deformity) > 180 degrees: clinical and radiographic outcomes of halo gravity traction and vertebral column resection (VCR).
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Boachie-Adjei O, Sacramento-Dominguez C, Ayamga J, Sackeyfio A, Duah HO, Yankey KP, Akoto H, Hodes R, Wulff I, and Pellise F
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- Adolescent, Humans, Osteotomy, Retrospective Studies, Spine diagnostic imaging, Spine surgery, Treatment Outcome, Scoliosis diagnostic imaging, Scoliosis surgery, Traction
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Study Design: Prospective case series OBJECTIVE: Results of surgical treatment of complex vertebral transposition "Gamma Deformity" > 180 degrees with halo gravity traction (HGT) and vertebral column resection (VCR). We recently published a novel classification system for complex spine deformities of which complex vertebral transposition > 180 degrees (Gamma; type 3) was described. Halo gravity traction (HGT) has been shown to mitigate surgical risk in complex spine deformity correction and in some cases obviates the need for three-column osteotomy. However, we are not aware of report of its utilization in treating Gamma deformities with or without vertebral column resection (VCR)., Methods: A consecutive series of 13 patients with Gamma deformity (GD) were prospectively enrolled at a single site in West Africa. Standard radiographs and 3D computerized tomography (CT) were done to assess coronal and sagittal vertebral transposition (CVT and SVT). The HGT with 50% of body weight was applied over several weeks followed by VCR. Demographics, operative data, radiographic parameters, and complications data were collected., Results: 13 pts with GD underwent HGT for an avg of 110 days prior to definitive surgery. Etiologies were Congenital-11 pts and Neurofibromatosis-2 pts. Average age: 17.8 years; Pts were reviewed at 3 months post-op and at minimum 2-year follow-up. Preop myelopathy was present in five patients. Pre-op CVT avg 75% and was corrected in all cases post-op. SVT avg 211 deg and improved with HGT by 36% and corrected to 53 deg (74% correction) post-op. Thoracic kyphosis avg -42 deg and averaged 48 deg post-op. Intra-op spinal cord monitoring (SCM) alerts occurred in 8 pts (61%). Post-operative LEM deficits occurred in 5 pts: 2 fully recovered by 3 months and 2 year follow-up, while the remaining 3 improved but had residual motor deficits at final follow-up. There was one post-operative mortality., Conclusion: The management of complex vertebral transposition (Gamma deformity) > 180 degrees with HGT prior to VCR is not only effective in some patients, but also associated with high SCM alerts and neurologic injury rates. Myelopathic patients with thoracic deformities are at higher risk of developing permanent neurologic deficits. Surgeons should be aware of this rare and unusual deformity and consider HGT and VCR bearing in mind the technical challenges and high complication rate.
- Published
- 2021
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12. The efficacy and safety of intraoperative acute normovolaemic haemodilution in complex spine surgery in a private surgical facility in Ghana.
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Wulff I, Duah HO, Oteng-Yeboah A, Tutu HO, Yankey KP, Essel AS, Akoto H, and Boachie-Adjei O
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Objectives: To assess the safety and clinical benefits of intraoperative acute normovolaemic haemodilution (ANH) in complex spine surgery., Design: Prospective comparative cohort study., Setting: A private orthopaedic hospital in Ghana., Patients: Seventy-six patients who underwent complex spine deformity surgery., Interventions: Patients were randomly assigned to two groups. 45 patients to the acute normovolaemic haemodilution (ANH) or Group 1 and 31patients to the non-ANH or Group 2. Following anesthetic administration and before incision, autologous blood was collected from patients in Group1 and was reinfused during/shortly after surgery while patients in Group2 were transfused with compatible allogeneic blood intraoperatively., Main Outcome Measures: Changes in haemodynamic parameters and incidence of allogeneic transfusions and related complications., Results: The mean age (years), gender ratio, deformity size and aetiology, fusion levels, and operative times were similar in both groups. Blood loss (ml) of patients in groups 1 and 2 were 1583ml± 830.48 vs 1623ml ± 681.34, p=0.82, respectively. The rate of allogeneic blood transfusion in groups 1 and 2 were 71% vs 80.65%, p=0.88, respectively. Haemoglobin levels (g/dL) in groups 1 and 2 were comparable in both groups at Post-operative Day (POD) 0 and POD 1. Incidence of minor allogeneic transfusion reaction was 1/45 vs 1/31, p=0.80, group-1 and group-2, respectively., Conclusion: Acute normovolaemic haemodilution can be safely performed in complex spine surgery in underserved regions. However, its use does not obviate allogeneic transfusion in patients with complex spine deformities in whom large volumes of blood loss is expected., Funding: None declared., Competing Interests: Conflict of Interest: OB-A (grants, personal fees and other from K2M, other from WEIGAO, outside the submitted work). For the remaining authors none were declared., (Copyright © The Author(s).)
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- 2021
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13. The Use of Halo Gravity Traction in the Treatment of Severe Early Onset Spinal Deformity.
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Iyer S, Duah HO, Wulff I, Osei Tutu H, Mahmud R, Yankey KP, Akoto H, and Boachie-Adjei O
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- Adolescent, Child, Female, Humans, Kyphosis surgery, Kyphosis therapy, Male, Neurosurgical Procedures, Postoperative Period, Preoperative Care methods, Prospective Studies, Radiography, Reoperation, Respiratory Function Tests, Retrospective Studies, Scoliosis surgery, Scoliosis therapy, Traction statistics & numerical data, Treatment Outcome, Spinal Curvatures surgery, Spinal Curvatures therapy, Traction methods
- Abstract
Study Design: Retrospective Review of Prospective cohort., Objective: To describe the feasibility of preoperative halo gravity traction (HGT) with subsequent growing rod/guided growth (GR/GG) placement in early onset spinal deformity (EOSD)., Summary of Background Data: In children with severe EOSD, primary implantation of GR/GG constructs is not always possible. We describe a staged protocol with preoperative HGT followed by GR/GG implantation., Methods: EOSD patients treated with HGT prior to GR/GG implantation were included. HGT used traction up to 50% body weight for 4 to 29 weeks. Pulmonary function tests (PFTs) were performed before and after HGT. Coronal Cobb (CC) and Sagittal Cobb (SC) angles were measured on the Pre-HGT, Post-HGT and 6 week postop x-rays., Results: Thirty patients were included. Average age at GR/GG implantation was 9 years. Most cases (n = 24, 80%) were idiopathic. Most pts had kyphoscoliosis (n = 16, 53.3%). Pre-HGT CC averaged 112 ± 22° and SC averaged 106 ± 26°. CC and SC improved 29% after HGT. There was a significant improvement in body mass index following HGT. CC improved further to 70 ± 14° (36% vs. pre-HGT) and SC to 63 ± 21° (41%) with GR/GG placement. HGT-related complications occurred in nine patients (30%); eight pin site infections, one cranial abscess. Most HGT complications were managed with local pin care and oral antibiotics. Halo revision was required in two pts (6.7%). There was no change in PFTs with HGT (P > 0.05). Averagely, 14 levels were spanned during GR/GG implantation; two patients required vertebral column resection. Surgical complications occurred in nine (30%) patients. At average 16 month follow-up, seven patients (23.3%) required reoperation., Conclusion: Preoperative HGT can make severe EOSD curves amenable to GR/GG implantation. HGT results in ∼30% correction with improvement to ∼35-40% following GR/GG. HGT has a 30% complication rate but most are pin-site infections managed with pin-site care and oral antibiotics; 6.7% of patients require revision., Level of Evidence: 4.
- Published
- 2019
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14. A novel radiographic classification of severe spinal curvatures exceeding 100°: the Omega (Ω), gamma (γ) and alpha (α) deformities.
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Karikari IO, Pang H, Yankey KP, Duah HO, Akoto H, Hodes R, and Boachie-Adjei O
- Subjects
- Adolescent, Adult, Female, Humans, Imaging, Three-Dimensional methods, Kyphosis classification, Kyphosis diagnostic imaging, Kyphosis pathology, Kyphosis surgery, Male, Prospective Studies, Radiographic Image Interpretation, Computer-Assisted methods, Radiography, Scoliosis classification, Scoliosis diagnostic imaging, Scoliosis pathology, Scoliosis surgery, Spinal Curvatures classification, Spinal Curvatures pathology, Spinal Curvatures surgery, Tomography, X-Ray Computed methods, Young Adult, Spinal Curvatures diagnostic imaging
- Abstract
Purpose: For spine curvatures with Cobb angles > 100°, curve classification and characterization become more difficult with conventional radiographs. 3-D computerized axial tomography scans add relevant information to categorize and describe a new classification to aid preoperative assessment in communication and patient evaluation. The purpose of this study is to describe a radiographic classification system of curves exceeding 100°., Methods: A consecutive series of patients with curves exceeding 100° underwent a full spine radiographic review using conventional radiographs and 3-D CT. A descriptive analysis was performed to categorize curves into 4 main types (1, 2, 3 and 4) and 6 subtypes (1C, 1S, 1CS, 2P, 2D and 2PD) based on the location of the Cobb angle of the major scoliotic and kyphotic deformity as well as the location of the upper/lower end vertebra relative to the apical vertebra., Results: A total of 98 patients met the inclusion criteria. There were 51 males and 47 females with an average age of 17.8 ± 4.5 years. The diagnosis included idiopathic (48); congenital (24); neuromuscular (4); and neurofibromatosis (2). The mean major coronal and sagittal Cobb (kyphosis) were 131.2° ± 23.4° and 154 ± 45.6, respectively. The classification scheme yielded 4 main types (1, 2, 3 and 4) and 6 subtypes under types 1 and 2 (1C, 1S, 1CS, 2P, 2D and 2PD)., Conclusions: Our study describes a novel method of classifying severe spinal curvatures exceeding 100° using erect AP/lateral radiographs and 3-D CT reconstructive images. We hope that the descriptive analysis and classification will expand our understanding of these complex deformities. These slides can be retrieved under Electronic Supplementary Material.
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- 2019
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15. Halo Gravity Traction Can Mitigate Preoperative Risk Factors and Early Surgical Complications in Complex Spine Deformity.
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Iyer S, Boachie-Adjei O, Duah HO, Yankey KP, Mahmud R, Wulff I, Tutu HO, and Akoto H
- Subjects
- Gravitation, Humans, Osteotomy adverse effects, Osteotomy statistics & numerical data, Retrospective Studies, Risk Factors, Treatment Outcome, Postoperative Complications epidemiology, Postoperative Complications prevention & control, Spinal Curvatures surgery, Traction
- Abstract
Study Design: Retrospective review of prospective cohort., Objective: We sought to examine the role of halo gravity traction (HGT) in reducing preoperative surgical risk., Summary of Background Data: The impact of HGT on procedure choice, preoperative risk factors, and surgical complications has not been previously described., Methods: Patients treated with HGT before primary surgery were included. The FOCOS Score (FS) was used to quantify operative risk. FS was calculated using patient-factors (ASIA, body mass index, etiology), procedure-factors (PcF; osteotomy planned, number of levels fused, etc.), and curve magnitude (CM). Scores ranged from 0 to 100 with higher scores indicating increased risk. FS was calculated before and after HGT to see how changes in FS affected complication rates., Results: A total of 96 patients were included. Halo-related complications occurred in 34% of patients but revision was required in only 8.3%. Average FS improved by 18 points after HGT. CM, PcF, and patient-factors all improved (P < 0.05). The greatest changes were in CM and PcF. The planned rate of three-column osteotomies dropped from 91% to 38% after HGT. FS (area under the curve [AUC]: 0.68, P = 0.023) and change in FS (AUC: 0.781, P < 0.001) was successfully able to predict the rate of surgical complications. A preoperative FS of 74 was identified as a cut-off for a higher rate of surgical complications (sensitivity 58.8%, specificity 74.7%). Patients with a reduction in FS < = 10pts were five times more likely to have a complication (relative risk 5.2, 95% confidence interval: 1.9-14.6, P < 0.001). A multivariate regression showed that change in FS was an independent predictor of complication rates (P < 0.05)., Conclusion: FS can successfully predict surgical risk in pediatric patients with complex spinal deformity. Preoperative HGT can reduce FS and surgical risk by improving CM, lowering three-column osteotomies use, and improving body mass index. A reduction in FS after HGT predicts a lower rate of surgical complications., Level of Evidence: 3.
- Published
- 2019
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16. Comprehensive Assessment of Outcomes From Patients With Severe Early-onset Scoliosis Treated With a Vertebral Column Resection: Results From an SRS Global Outreach Site (FOCOS) in Ghana.
- Author
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Verma K, Slattery C, Duah H, Yankey KP, Mundis G, and Boachie-Adjel O
- Subjects
- Adolescent, Blood Loss, Surgical statistics & numerical data, Child, Child, Preschool, Databases, Factual, Female, Follow-Up Studies, Ghana, Humans, Kyphosis diagnostic imaging, Male, Operative Time, Osteotomy adverse effects, Radiography, Reoperation, Retrospective Studies, Risk, Scoliosis diagnostic imaging, Kyphosis surgery, Osteotomy methods, Outcome Assessment, Health Care statistics & numerical data, Scoliosis surgery, Spine surgery
- Abstract
Background: Early-onset scoliosis (EOS) remains a challenging pediatric spine condition to manage. Some severe deformities can be managed with a vertebral column resection (VCR), which is fraught with high complication rates and the outcomes have not been well reported. The purpose of this study is to provide an assessment of operative, radiographic, and clinical outcomes from children diagnosed with severe EOS treated with a VCR., Methods: We performed a retrospective review of prospectively collected data. Basic demographic data was collected along with the diagnosis, procedure performed, FOCOS risk score, blood loss (estimated blood loss), operative time, neuromonitoring events, intraoperative complications, and clinical follow-up. Coronal and sagittal radiographic parameters were measured by the first author., Results: We identified 14 patients with posttuberculosis deformity (n=7) or congenital deformity (n=7) that underwent VCR between 2013 and 2016 (5 female; age, 7.7±3 y; body mass index, 17.7±2.8). There was significant improvement in coronal radiographic parameters (primary curve: 55 to 21 degrees, secondary: 37 to 13 degrees, T1-12 length: 137 to 151 mm, T1-S1 length: 219 to 271 mm, P<0.05) and sagittal parameters (kyphosis: 85 to 41 degrees, compensatory lordosis 56 to 39 degrees, P<0.001). There was no change in chest width, sagittal vertical axis, or pelvic tilt. Mean proximal junctional kyphosis (PJK) angle was 12±9 degrees and distal junctional kyphosis angle was 9±17 degrees. Estimated blood loss was 860±520 mL and operative time was 200±66 minutes. Seven cases had neuromonitoring changes that improved with corrective maneuvers and blood pressure elevation. Three patients required reoperation for junctional breakdown with 1 having a third operation for an infection, while 2 additional patients had evidence of radiographic PJK., Conclusions: VCR in the setting of EOS has excellent radiographic outcomes but a high complication profile. Half of these cases had neuromonitoring changes intraoperatively that improved without lasting neurological deficit. Three patients had PJK and 1 had an infection requiring reoperation., Level of Evidence: Level IV-case series.
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- 2018
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17. Spinal cord and spine trauma in a large teaching hospital in Ghana.
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Ametefe MK, Bankah PE, Yankey KP, Akoto H, Janney D, and Dakurah TK
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- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Ghana epidemiology, Hospitals, Teaching, Humans, Male, Middle Aged, Retrospective Studies, Spinal Cord Injuries complications, Spinal Cord Injuries etiology, Spinal Cord Injuries therapy, Spinal Injuries complications, Spinal Injuries etiology, Spinal Injuries therapy, Young Adult, Spinal Cord Injuries epidemiology, Spinal Injuries epidemiology
- Abstract
Introduction: Spinal cord injury (SCI) is a devastating injury, with its effect going beyond the injured patient to the care givers and family and with economic implications that can be long lasting. The study determined the occurrence and patterns of SCI and spine injury patterns, treatment and treatment outcomes in a large tertiary health facility in Ghana., Methods: This was a retrospective review of health records of patients at the Korle bu Teaching Hospital, Ghana. Data on 185 patients were collected over a period of 18 months from September 2012 to February 2014. Data were collected on basic demographic characteristics (age distribution), cause of SCI, type and severity of injuries, mode of transportation to the hospital and treatment modalities. In addition, data were collected on the imaging techniques used, waiting time and delays encountered, complications and follow-up. Descriptive statistics were used to analyze data using Windows Excel 2007 version., Results: A total of 185 patients were treated in the study period, 125 (67.6%) patients had cervical spine injury, 33 (17.8%) had thoracic spine injuries and 27 (14.6%) had lumbar injuries. In all, 141 (76%) were males. The age range of patients was 4 years to 86 years; mean age was 36.25±13.62 years. Spinal injuries were most common in the 31-45-year age group, followed by 16-30-year group. Most prevalent cause of spinal injury was road traffic accident (RTA), 130 (70.3%), whereas assault was the least common, 5 (2.7%). Delay in getting imaging studies conducted was high; 43 (23%) of the computed tomography scans required were performed after 48 h of admission. Only 76 (41%) patients were able to afford the cost of magnetic resonance imaging. Pressure sore (23%) and pneumonia (21%) were the most common complication during admission., Conclusion: RTA was the most common cause of spinal injuries and occurred in the relatively young population, especially among men. Structured public education and enforcement of road safety measures are imperative. Rapid response to management of patients with SCI at the teaching hospital needs attention by hospital management.
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- 2016
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18. Pneumatic reduction of intussusception in children at the Komfo Anokye Hospital, Kumasi, Ghana.
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Abantanga FA, Amoah M, Adeyinka AO, Nimako B, and Yankey KP
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- Adolescent, Child, Child, Preschool, Female, Ghana, Humans, Infant, Male, Prospective Studies, Air Pressure, Enema, Insufflation, Intussusception therapy
- Abstract
Objective: To evaluate the role of pneumatic reduction in the management of intussusception in children in the setting of a sub-Saharan African nation., Design: Prospective case series., Setting: Tertiary care teaching hospital in Kumasi, Ghana., Subjects: Forty four children, aged 4 months to 13 years, 28 boys and 16 girls, were admitted with a clinical diagnosis of intussusception and confirmed by ultrasonography., Interventions: Twenty two children had air enema reduction of the intussusception attempted in the operation theatre under general anaesthesia. The average pressure used for air enema reduction of the intussusceptions was 110.4 mm Hg., Main Outcome Measures: Success of pneumatic reduction, morbidity and mortality., Results: Overall air enema reduction of intussusception was successful in 59.1% of children who underwent this procedure. There were no deaths among children who had a successful air enema reduction of intussusception. One child (11.1%) out of nine who had laparotomy done after a failed pneumatic reduction died. The average length of hospital stay was shorter in those with successful air enema reduction (3.8 +/- 2.3 days, 95% Confidence Interval [CI] = 2.4 to 5.2) than those who had a laparotomy performed for manual reduction of the intussusception after a failed pneumatic reduction (6.7 +/- 5.1 days, 95% CI = 33 to 9.9)., Conclusion: Although the sample size is small, pneumatic reduction of intussusception in children without peritonitis is possible, practical, and reliable and must be tried first, preferably under general anaesthesia in our sub-region before proceeding to laparotomy in case of failure.
- Published
- 2008
- Full Text
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