33 results on '"Yashiro, Hiroaki"'
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2. Discovery of a novel series of medium-sized cyclic enteropeptidase inhibitors
3. Selective Acetyl-CoA Carboxylase 1 Inhibitor Improves Hepatic Steatosis and Hepatic Fibrosis in a Preclinical Nonalcoholic Steatohepatitis Model
4. Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis
5. Enteropeptidase inhibition improves obesity by modulating gut microbiota composition and enterobacterial metabolites in diet-induced obese mice
6. Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus
7. Microbial dietary protein metabolism regulates GLP-1 mediated intestinal transit
8. The Effects of TAK-875, a Selective G Protein-Coupled Receptor 40/Free Fatty Acid 1 Agonist, on Insulin and Glucagon Secretion in Isolated Rat and Human Islets
9. Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease
10. Design, Synthesis, and Biological Evaluation of a Novel Series of 4-Guanidinobenzoate Derivatives as Enteropeptidase Inhibitors with Low Systemic Exposure for the Treatment of Obesity
11. Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol‐associated liver disease
12. The Cavity Structure for Docking the K+-competitive Inhibitors in the Gastric Proton Pump
13. GS009 - Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease
14. Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis
15. Discovery and characterization of a small‐molecule enteropeptidase inhibitor,SCO‐792
16. SCO‐792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice
17. 脂肪酸代謝により生じる生理シグナルの調節と抗肥満および抗糖尿病作用に関する基盤研究
18. Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates hepatic fibrosis and steatosis in a murine model of nonalcoholic steatohepatitis
19. A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice
20. Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors
21. Present Status of the Nd:YAG Thomson Scattering System Development for Time Evolution Measurement of Plasma Profile on Heliotron J
22. Recent Progress in Plasma Control Studies on the Improvement of Plasma Performance in Heliotron J
23. Physics of Heliotron J Confinement
24. Present Status of the Nd:YAG Thomson Scattering System Development for Time Evolution Measurement of Plasma Profile on Heliotron J
25. The Effects of TAK-875, a Selective G Protein-Coupled Receptor 40/Free Fatty Acid 1 Agonist, on Insulin and Glucagon Secretion in Isolated Rat and Human Islets
26. Recent Progress in Plasma Control Studies on the Improvement of Plasma Performance in Heliotron J
27. Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor
28. Numerical Analysis of ICRF Minority Heating in Helitoron J
29. Design of a new high repetition rate Nd:YAG Thomson scattering system for Heliotron J
30. Physics of Heliotron J Confinement
31. Cibenzoline, an ATP-sensitive K+channel blocker, binds to the K+-binding site from the cytoplasmic side of gastric H+,K+-ATPase
32. Significance of Lysine/Glycine Cluster Structure in Gastric H+,K+-ATPase.
33. Discovery and characterization of a small-molecule enteropeptidase inhibitor, SCO-792.
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