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Ectopic salivary gland tissue (ESGT) is salivary tissue located outside the major, minor and accessory salivary glands. Neoplasms rarely arise from ESGT, let alone carcinoma expleomorphic adenoma (CEPA) which is a malignant tumour that arises from the epithelial component of pleomorphic adenoma. It usually occurs in the parotid gland and in lesser instances, from submandibular gland or minor salivary glands. Herein, we report a rare case of CEPA in right supraclavicular ESGT of a 67-year-old lady.She underwent complete surgical excision of the mass and is free from any recurrence to date. Brief review of pathogenesis, clinical features and treatment of ectopic CEPA are discussed. A thorough review of the English literature reveals that our patient may be the second case of ectopic CEPA in the neck region ever reported to date. Bangladesh Journal of Medical Science Vol.20(3) 2021 p.658-661

Ectopic thyroid tissue occurs in about 1 in 10,000 people. It can be seen anywhere from foramen caecum to lower neck region. But, it is rarely seen in a lateral neck mass, especially in branchial cleft cyst. Transformation to a malignant state in an ectopic thyroid tissue is uncommon, with most of the diagnoses found routinely through the post-operative histopathological analysis. Hereby, we report a rare case of an ectopic papillary thyroid carcinoma with an initial pre-operative diagnosis of a branchial cleft cyst. However, no primary thyroid gland malignancy was found. The pathophysiology and rarity of these disorders are explored. A high index of suspicion of ectopic tissue and malignancy must be in mind while attending to patients with long-standing, uninvestigated lateral neck masses. Excision biopsy and histopathological study are the two definitive steps to be undertaken

Acute lymphoblastic leukaemia (ALL) in infants below 1 year of age contributed 2.5–5% of childhood ALL incidence. Children with ALL commonly presented with fever, bruising, mucosal bleeding, bone pain, pallor, hepatosplenomegaly, and lymphadenopathy. Common extra medullary leukaemic infiltration has also been reported at diagnosis of ALL to sites such as the liver, spleen, lymph nodes, brain, testes and even nephromegaly. However ALL presented with parotid infiltration is exceedingly rare. We herein present a case of unilateral parotid enlargement in a child with newly diagnosed ALL. This unusual presentation focuses on the importance of considering ALL in the differential diagnosis of parotid enlargement especially when associated with abnormal blood counts.

Squamous cell carcinoma (SCC) of the nasopharynx is amongst the most common head and neck cancers. The most common distant metastases are to the bone, liver and lung. Herein, we are reporting a rare case of a 61-year-old man with nasopharyngeal carcinoma (NPC) who presented with 3 weeks history of blood streaked sputum, post nasal drip and blocked nose with no history of epistaxis, tinnitus and unilateral hearing loss. Almost 2 years upon completion of his concurrent chemotherapy and radiotherapy, he developed a right hypochondrium mass and underwent colonoscopy which revealed a mass in ascending colon and which was then subsequently resected via right hemicolectomy. Histological analyses from the resected specimen confirmed its nasopharyngeal origin.