19 results on '"Yazla M"'
Search Results
2. Comparison of standard prophylactic and preemptive therapeutic low molecular weight heparin treatments in hospitalized patients with COVID-19
- Author
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Copur, B., primary, Surme, S., additional, Sayili, U., additional, Tuncer, G., additional, Zerdali, E., additional, Yazla, M., additional, Nakir, I. Y., additional, Buyukyazgan, A., additional, Kurt-Cinar, A. R., additional, Balli, H., additional, Kurekci, Y., additional, Pehlivanoglu, F., additional, and Sengoz, G., additional
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- 2021
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3. Compliance Evaluation with ChatGPT for diagnosis and treatment in patients brought to the ED with a Preliminary Diagnosis of Stroke.
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Yazla M and Sarcan E
- Abstract
Objectives: Chat Generative Pre-trained Transformer (ChatGPT) is a natural language processing product developed by OpenAI. Recently, the use of ChatGPT has gained attention in the field of healthcare, particularly for its potential applications in diagnostic and decision-making support. While its utility is still being explored, it shows promise as a supplementary tool in these contexts. This study aims to evaluate the potential of ChatGPT in making decisions about 'transportation to the stroke center, suspicion of large vessel occlusion and treatment decisions' of patients brought to the emergency department by ambulance with a preliminary diagnosis of stroke., Methods: All patients with a stroke code who were transferred to the emergency department (ED) of a tertiary care hospital, Ankara Etlik City Hospital, by ambulance between November 1, 2023, and April 30, 2024, during designated stroke team coverage periods were included in the study. Unlike many stroke centers that operate continuously 24/7, our institution follows a structured on-call system, where specialized stroke teams are assigned time slots to provide stroke care. Data were collected from prehospital records, ED notes, and hospital imaging and treatment records. ChatGPT's decisions were compared to gold standard outcomes using Cohen's kappa test, with sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) calculated for each directive., Results: A total of 512 patients were analyzed, and ChatGPT's decisions were compared with the patients' final diagnoses and treatments. Analysis comparing ChatGPT's decisions to patient outcomes across prehospital stroke suspicion, large vessel occlusion diagnosis, and treatment phases showed significant agreement (p < 0.001, Kappa: 0.540-0.562). While the sensitivity of the diagnosis of stroke was 91%, the NPV was found to be 98% in patients requiring intravenous tissue plasminogen activator and large vessel occlusion, 97% NPV in patients requiring mechanical thrombectomy., Conclusions: ChatGPT shows promise as a decision-support tool for identifying acute ischemic stroke and determining treatment needs in prehospital and ED settings. However, its reliance on predefined data highlights the need for physician supervision to address clinical complexities and ensure patient safety. Integrating ChatGPT as an adjunct rather than a standalone system can enhance decision-making efficiency while maintaining high-quality care.
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- 2025
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4. Incidence and outcomes of dysnatremia in crush injury patients admitted to Türkiye's largest hospital following the Kahramanmaraş earthquake.
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Yazla M and Aksoy FM
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- Humans, Male, Female, Adult, Retrospective Studies, Middle Aged, Incidence, Turkey epidemiology, Young Adult, Aged, Adolescent, Hyponatremia epidemiology, Hyponatremia etiology, Emergency Service, Hospital, Prognosis, Earthquakes, Crush Injuries
- Abstract
Objectives: Dysnatremia is a critical electrolyte disturbance that can significantly impact the prognosis of trauma patients by influencing fluid balance, neurological function, and hemodynamics. Although sodium disorder is common in hospitalized patients, few studies have specifically examined the incidence of dysnatremia in patients presenting to the emergency department for post-earthquake trauma. The aim of this study is to evaluate the incidence of dysnatremia and the prognosis of patients with dysnatremia in trauma patients admitted to our center after the Kahramanmaraş earthquake., Materials and Methods: Between February 6th, 2023 and February 20th, 2023, a total of 422 patients with earthquake-related crush injuries after the Kahramanmaras earthquake were retrospectively analyzed. Patients were divided into two groups: the survivor group and the exitus group. Then, patients with dysnatremia were evaluated. Age, gender, the city where patients came from, type of presentation, injured organ systems and extremities, laboratory findings, ward admission, intensive care admission, GCS, MESS, ISS, RTS, TRISS, and hemodialysis sessions were analyzed., Results: A total of 422 earthquake victims with crush injuries were included in the study. Dysnatremia was present in 28% of the patients, and these patients had a longer hospital stay. GCS was lower, MESS and ISS values were higher, and survival rates according to TRISS were lower. Multiple extremity trauma, crush syndrome, and dialysis rates were more common in the dysnatremia group. Additionally, fasciotomy, amputation and mortality rates were higher in the dysnatremia group., Conclusion: Dysnatremia is a common finding in patients with crush injuries and is associated with more severe trauma and poorer clinical outcomes. This study highlights the need for close monitoring and management of sodium disturbances in trauma patients, not only in the context of earthquakes but across various disaster scenarios. Recognizing and addressing dysnatremia can contribute to improved patient outcomes in disaster and emergency settings., Competing Interests: Declarations. Ethics approval and consent to participate: An application was made to Ankara Etlik City Hospital Ethics Committee for the study with the number AEŞH-BADEK-2024-063, and it was decided that ethics committee approval was not required. Since our study was designed retrospectively and was organized with information obtained from patient records in the hospital information management system, no consent was obtained from the patients. Consent for publication: Not applicable. Competing interests: All of the authors work in the same hospital with one of their editors, Burak Katipoğlu. We have collaborated together before., (© 2024. The Author(s).)
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- 2025
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5. Mapping Trends Regarding the Cardiopulmonary Resuscitation: A Bibliometric Analysis of the Top 100 Cited Articles.
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Turan ÖF, Yardımcı AS, Yazla M, Işık Nİ, Koçak AO, and Katipoğlu B
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Introduction: Despite significant medical and technological advancements, cardiac arrest remains a critical public health concern due to its persistently high mortality and morbidity rates. Consequently, research on cardiopulmonary resuscitation (CPR) is of significant importance. Materials and Methods: This study presents a bibliometric analysis of the 100 most-cited articles in the field of CPR identified using the Scopus database without time restrictions. Analyses were conducted using VOSviewer and Bibliometrix software. Original research articles published in English were included. Results: The study revealed contributions from 798 distinct authors across 18 journals, with citation counts ranging from 218 least-cited articles to 1194 most-cited articles. The most recent article was published in 2020, and the most frequently used keywords were "CPR" and "heart arrest." In addition, 20% of the analyzed articles were funded by military organizations. Conclusion: This analysis highlights the significant contributions of emergency medicine researchers and the notable development of CPR literature, particularly between the late 1990s and the early 2000s. While the most-cited studies originated from journals with high H-indices, the citation frequency of these articles showed a consistent decline over time. Furthermore, impactful articles in this field were predominantly published in general medical journals rather than in specialized emergency medicine journals. This study provides a foundational resource for researchers, especially early career academicians, seeking to engage in CPR-related research., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2025 Ömer Faruk Turan et al. Emergency Medicine International published by John Wiley & Sons Ltd.)
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- 2025
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6. Predictive efficacy of immature granulocytes in acute complicated appendicitis.
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Yazla M, Kadıoğlu B, Demirdelen H, Aksoy FM, Özkan E, and Katipoğlu B
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- Humans, Female, Male, Adult, Middle Aged, Acute Disease, C-Reactive Protein analysis, Leukocyte Count, Young Adult, Sensitivity and Specificity, Procalcitonin blood, Adolescent, Emergency Service, Hospital, ROC Curve, Retrospective Studies, Appendicitis blood, Appendicitis surgery, Granulocytes, Biomarkers blood, Predictive Value of Tests
- Abstract
Objective: Acute appendicitis is the most common cause of acute abdomen. It is important to differentiate between complicated and uncomplicated appendicitis before surgery in the emergency department. Recently, immature granulocytes have become one of the biomarkers used as predictors of inflammation. The aim of this study was to determine whether immature granulocyte levels are a biomarker that can predict whether acute appendicitis is complicated or not in patients admitted to the emergency department., Methods: Patients aged 18 years and older who presented to the emergency department between May 1, 2023, and April 30, 2024, and were diagnosed with appendicitis were included in the study. Patients with a histopathologic diagnosis of acute appendicitis were divided into two groups: acute simple appendicitis (n=149) and acute complicated appendicitis (n=103). Demographic characteristics, imaging results, and laboratory results were recorded., Results: White blood cell, neutrophil count and percentage, lymphocyte count and percentage, immature granulocyte count and percentage, direct bilirubin, C-reactive protein, and procalcitonin values were found to be significantly higher in the complicated appendicitis group than in the uncomplicated group (p-values; 0.001, <0.001, <0.001, <0.001, 0.001, <0.001, <0.001, <0.001, <0.001, 0.016, <0.001, and 0.001, respectively). The immature granulocyte percentage was 92% specific for the diagnosis of complicated appendicitis at a cut-off value of 0.6., Conclusion: The immature granulocyte percentage may be useful as a predictive biomarker in the diagnosis of complicated acute appendicitis with a specificity of 92%. Additionally, the immature granulocyte percentage has a higher discrimination power than the immature granulocyte count, C-reactive protein, and procalcitonin.
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- 2024
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7. YouTube as a source of information in cardiopulmonary resuscitation for 2020 AHA Resuscitation Guidelines.
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Yazla M, Şafak T, Aksu ŞH, Savran K, Aydogan RF, Arslan M, Koçak AO, and Katipoğlu B
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- Humans, Cross-Sectional Studies, United States, Practice Guidelines as Topic, Information Dissemination methods, Information Sources, Social Media standards, Cardiopulmonary Resuscitation education, Cardiopulmonary Resuscitation standards, Video Recording, American Heart Association
- Abstract
Background: The Internet has transformed global information access, particularly through platforms like YouTube, which launched in 1995 and has since become the second largest search engine worldwide with over two billion monthly users. While YouTube offers extensive educational content, including health topics like cardiopulmonary resuscitation (CPR) and basic life support (BLS), it also poses risks due to potential misinformation. Our study focuses on evaluating the accuracy of CPR and BLS videos on YouTube according to the latest 2020 American Heart Association (AHA) guidelines. This research aims to highlight inconsistencies and provide insights into improving YouTube as a reliable educational resource for both lay rescuers and healthcare professionals., Methods: In this cross-sectional observational study, English YouTube videos uploaded between October 21, 2020, and May 1, 2023, were searched using keywords related to CPR and basic life support. Videos were assessed for their source, duration, views, use of human or mannequin models, and mean assessment scores by two emergency medicine physicians. A third physician's opinion was sought in cases of disagreement. The first assessment evaluated video validity based on specified information criteria, while the second assessed their ability to convey advanced medical information aligned with the 2020 AHA guidelines., Results: In this study, 201 English YouTube videos uploaded between October 21, 2020, and May 1, 2023, were evaluated based on search terms related to CPR and BLS, resulting in 95 videos meeting inclusion criteria after excluding 106 due to various reasons. Most included videos were from healthcare professionals (49.5%), followed by anonymous sources (29.5%) and official medical organizations (21.1%). Video durations ranged widely from 43 to 6,019 seconds, with an average of 692 seconds. Videos featuring mannequins predominated (91.6%), followed by those using human subjects (5.3%) or both (3.2%). Healthcare professional and official medical organization videos scoring significantly higher than those of unknown origin ( p = 0.001). Video length did not correlate significantly with view counts, although shorter videos under 5 minutes tended to have higher average views., Discussion: The results presented in this study demonstrated that English-language videos on YouTube related to BLS and CPR, throughout the study period, did not conform to the 2020 AHA guidelines in terms of providing basic information for lay rescuers. Furthermore, healthcare professionals cannot obtain advanced medical knowledge through these videos. We recommend a professional oversight mechanism in health-related videos that does not tolerate such misinformation., Competing Interests: The authors declare there are no competing interests., (©2024 Yazla et al.)
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- 2024
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8. A nationwide analysis of emergency medicine residents' CT interpretation in trauma: The Tract-EM study.
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Aslaner MA, Kadı G, Kesen S, Kılıç ACK, Coşkun Ö, Bildik F, Keleş A, Demircan A, Kılıç HK, Şişik B, Korkak ÖF, Çelik GK, Arslan V, Oskay A, Can Ö, Baykan N, Yaş SC, Yazla M, Yaka E, Efgan MG, İmamoğlu M, Ak A, Koca A, Çalışkan F, Yadigaroğlu M, Eroğlu SE, İbze S, Yaman M, Taş M, Ardıç Ş, Kozacı N, Çevik Y, Sabak M, Aygün A, Koşargelir M, Aslan YE, Altuntaş G, Acar N, and İlhan B
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- Humans, Cross-Sectional Studies, Turkey, Male, Female, Adult, Wounds and Injuries diagnostic imaging, Emergency Service, Hospital, Internship and Residency, Emergency Medicine education, Clinical Competence, Tomography, X-Ray Computed statistics & numerical data
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Objective: To evaluate the accuracy and determine the factors influencing trauma CT interpretation proficiency among emergency medicine (EM) residents in Turkey through the TraCT-EM study (Interpretation of Trauma CT by EMergency Physicians)., Methods: This nationwide, multicenter, cross-sectional study was conducted in 29 academic emergency departments (EDs) from April 2023 to March 2024. A total of 401 senior EM residents participated in the study, each interpreting a standardized set of 42 trauma CT series (cranial, maxillofacial, and cervical) derived from seven patients. Interpretation accuracy was assessed, and factors predicting interpretation failure were analyzed using univariate and multivariate regression models., Results: The median accuracy rate of residents was 64.9 %, with higher accuracy in normal CT findings. Using the Angoff method, 14 % of residents scored below the passing threshold. Factors associated with interpretation failure included shorter interpretation times (OR, 0.97; 95 % CI, 0.95-0.99), lower self-confidence in detecting serious pathologies (OR, 2.50; 95 % CI, 1.42-4.42), reliance on in-hospital radiology department reports (OR, 3.45; 95 % CI, 1.47-8.05), and receiving final radiology reports for CT scans (OR, 3.30; 95 % CI, 1.67-6.52), and lack of in-department training programs (OR, 2.51; 95 % CI, 1.34-4.70)., Conclusion: The TraCT-EM study highlighted a 65 % accuracy rate for senior EM residents in trauma CT interpretation, with specific predictors of failure identified. These findings suggest a need for tailored radiology education strategies to enhance training and competency in trauma CT interpretation for EM residents. Further optimization of educational programs could address these gaps, ultimately improving patient outcomes in trauma care., Competing Interests: Declaration of competing interest None., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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9. YouTube as a Source of Information in Trauma Management for ATLS (10th Edition) Guidelines: Evaluation of Trauma Management Videos on YouTube.
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Yazla M, Akyon SH, Aybayar EA, Gedikaslan S, Szarpak L, Turan OF, Smereka J, Ekici M, Kocak AO, and Katipoglu B
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Background: Trauma is one of the leading causes of mortality worldwide, and online platforms have become essential sources of information for trauma management. YouTube can play a significant role in helping people access medical information. Methods: YouTube was searched using the keywords management of trauma and assessment of trauma to identify relevant videos. Two authors independently evaluated the videos according to the ATLS (10th edition) guidelines, the modified DISCERN (m-DISCERN) scale, and the Global Quality Scale (GQS) criteria. The videos that met the study criteria were evaluated based on the provider, video length, and view count. Results: Out of 939 videos, 667 were excluded resulting in 272 videos included in the study. According to the ATLS (10th edition) guidelines, the median score for videos was 8 (IQR 7-8). Videos uploaded by official institutions and healthcare professionals received higher scores than from uncertain sources ( p = 0.003). According to the GQS, 86% of the videos were low or moderate quality; uncertain sources uploaded 78% of low-quality videos. Conclusion: YouTube is an information source about trauma management that contains videos of varying quality and has a broad audience. Official institutions and healthcare professionals should be aware of this evolving technology and publish up-to-date, accurate content to increase awareness about trauma management and help patients distinguish helpful information from misleading content., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2024 Merve Yazla et al.)
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- 2024
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10. Untangling diagnostic confusion in internal abdominal hernias.
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Surel AA, Işık Nİ, and Yazla M
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- Humans, Male, Female, Middle Aged, Retrospective Studies, Internal Hernia complications, Abdominal Pain, Hernia, Abdominal diagnostic imaging, Hernia, Abdominal surgery, Intestinal Obstruction etiology
- Abstract
Background: Internal hernias involve the herniation of intestines through mesenteric or peritoneal defects in the gastrointestinal system. Etiologically, they are generally classified as congenital or acquired. Internal hernias often present with non-specific symptoms. Despite the increased use of computed tomography (CT), discrepancies between imaging findings and diagnostic accuracy continue to pose challenges for clinicians. This study aims to compare the outcomes of patients presenting to the emergency department with abdominal pain and receiving a preliminary internal hernia diagnosis through CT, followed by laparotomy., Methods: Our research is a retrospective, observational, and descriptive study. It includes patients presenting to the emergency department with abdominal pain, who were provisionally diagnosed with internal hernia based on CT. Patient data recorded age, gen-der, CT-identified internal hernia type, surgery, diagnoses, hospitalization status, duration of hospital stay, bowel resection, mortality, and blood parameters. The Welch classification was used to categorize internal hernia types, with eight types examined., Results: Among 112 patients with a preliminary internal hernia diagnosis based on abdominal CT, the median age was 52 years. Of these, 46 were female and 66 were male. Among all patients, 87 were admitted to the hospital for observation and surgery, while 25 were discharged after emergency department. Paraduodenal hernias were the most common provisional diagnosis (48 cases). Among these patients, 45 were discharged after symptom relief and were advised for elective re-evaluation. The exact diagnosis for these pa-tients remains unknown. Post-surgery, the diagnosis of internal hernia was confirmed in 32 cases. Among them, 15 were female and 17 were male, with a median age of 52. The median hospital stay for patients diagnosed with internal hernia was 5 days. Although acquired hernias exhibited higher resection and mortality rates, no statistically significant difference was found. Thirty-five cases received dif-ferent diagnoses: 19 had brid ileus, five had volvulus, six had acute appendicitis, one had duodenal perforation, three had gynecological malignancies, and one had renal malignancy., Conclusion: Although internal hernias are rare, early diagnosis and treatment are very important due to the high risk of death. The study findings indicate that increased CT utilization leads to earlier diagnosis and treatment, resulting in improved prognosis for patients. This study holds one of the largest case series in the literature. It provides a novel perspective by evaluating radiologically-diagnosed cases, confirming diagnoses post-surgery, and comparing conditions that mimic internal hernias, thereby making a valuable contribution to the literature.
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- 2023
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11. Change in Rates of HBsAg and Anti-HBs in Şırnak 20 Years After Introduction of Hepatitis B Vaccine into Routine Infant Immunization Program.
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Şahin M and Yazla M
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Objectives: This study aimed to monitor the change in the rate of hepatitis B infections in Şırnak, a province in south-eastern Turkey, and to determine the rate of immunization for hepatitis B in this region after the national immunization program covered hepatitis B., Materials and Methods: This retrospective study included patients born in 1998 or after and applied to different outpatient clinics in the province between April 2017 and June 2018. Patients in this study were screened for HBsAg and anti-HBs for various reasons. We analyzed confirmed HBsAg and anti-HBs positive results according to gender, age, and vertical transmission. Anti-HBs-positive patients were divided into four groups according to their ages, and the groups were compared., Results: Out of 2713 patients, 1530 (56.4%) were male, and the mean age was 12.77 (0-20). Four patients (0.14%) were HBsAg positive, and the anti-HBs positivity rate was 61.22%. The difference was statistically significant when the anti-HBs positivity rate was compared between the age groups ( p <0.001). The highest anti-HBs positivity rate was found in the 0 to 5 age group., Conclusion: There has been a significant decrease in hepatitis B virus infection rates after introducing the hepatitis B vaccine into routine infant immunization programs. The widespread introduction of hepatitis B vaccination should be targeted in Turkey, considering its geographical and sociocultural diversity., Competing Interests: The authors declare no conflict of interest., (Copyright © 2024 Infectious Diseases and Clinical Microbiology.)
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- 2023
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12. Long-term effects of COVID-19 on lungs and the clinical relevance: a 6-month prospective cohort study.
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Tuncer G, Geyiktepe-Guclu C, Surme S, Canel-Karakus E, Erdogan H, Bayramlar OF, Belge C, Karahasanoglu R, Copur B, Yazla M, Zerdali E, Nakir IY, Yildirim N, Kar B, Bozkurt M, Karanalbant K, Atasoy B, Takak H, Simsek-Yavuz S, Turkay R, M Sonmez M, Sengoz G, and Pehlivanoglu F
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- Humans, Prospective Studies, Disease Progression, Laboratories, Lung diagnostic imaging, COVID-19
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Background: We aimed to explore the prevalence of prolonged symptoms, pulmonary impairments and residual disease on chest tomography (CT) in COVID-19 patients at 6 months after acute illness. Methods: In this prospective, single-center study, hospitalized patients with radiologically and laboratory-confirmed COVID-19 were included. Results: A high proportion of the 116 patients reported persistent symptoms (n = 54; 46.6%). On follow-up CT, 33 patients (28.4%) demonstrated residual disease. Multivariate analyses revealed that only neutrophil-to-lymphocyte ratio was an independent predictor for residual disease. Conclusion: Hospitalized patients with mild/moderate COVID-19 still had persistent symptoms and were prone to develop long-term pulmonary sequelae on chest CT. However, it did not have a significant effect on long-term pulmonary functions.
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- 2023
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13. Novel biomarker-based score (SAD-60) for predicting mortality in patients with COVID-19 pneumonia: a multicenter retrospective cohort of 1013 patients.
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Surme S, Tuncer G, Bayramlar OF, Copur B, Zerdali E, Nakir IY, Yazla M, Buyukyazgan A, Cinar AR, Kurekci Y, Alkan M, Ozdemir YE, Sengoz G, and Pehlivanoglu F
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- Aged, Albumins, Biomarkers, Female, Hospital Mortality, Humans, Male, Middle Aged, Prognosis, Retrospective Studies, SARS-CoV-2, Severity of Illness Index, COVID-19
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Background: The aim was to explore a novel risk score to predict mortality in hospitalized patients with COVID-19 pneumonia. Methods: This was a retrospective, multicenter study. Results: A total of 1013 patients with COVID-19 were included. The mean age was 60.5 ± 14.4 years, and 581 (57.4%) patients were male. In-hospital death occurred in 124 (12.2%) patients. Multivariate analysis revealed peripheral capillary oxygen saturation (SpO2), albumin, D-dimer and age as independent predictors. The mortality score model was given the acronym SAD-60, representing S pO2, A lbumin, D -dimer, age ≥60 years. The SAD-60 score (0.776) had the highest area under the curve compared with CURB-65 (0.753), NEWS2 (0.686) and qSOFA (0.628) scores. Conclusion: The SAD-60 score has a promising predictive capacity for mortality in hospitalized patients with COVID-19.
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- 2022
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14. Diagnostic Accuracy of Early Systolic Notching in Pulmonary Embolism.
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Aslaner MA, Karbek Akarca F, Aksu ŞH, Yazla M, Can Ö, Kuş G, Çelik A, Özkan S, İbze S, Yamanoğlu A, Yazıcı MM, Yürüktümen Ünal A, and Demircan A
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- Computed Tomography Angiography, Emergency Service, Hospital, Humans, Prospective Studies, Reproducibility of Results, Ultrasonography, Pulmonary Embolism diagnostic imaging
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Objective: Recently, a cardiac sonography finding, early systolic notching (ESN), was reported with high sensitivity and specificity for the diagnosis of pulmonary embolism (PE) in a limited population. The aim of this study was to determine the diagnostic accuracy of ESN finding for PE in emergency department (ED) patients., Method: This prospective multicenter study was conducted in 4 academic EDs. All patients who underwent computed tomography angiography for suspected PE were included in the study. After inclusion, cardiac ultrasound including the right ventricular outflow tract Doppler signal was performed. The diagnostic tests of ESN finding were used for PE and its subgroups., Results: In the study, 183 of 201 patients met the study criteria. Of all patients, 52.5% had PE (n = 96), and 19.7% (n = 36) had ESN finding. In all ED patients, the sensitivity of ESN for PE was 34% (95% CI 25-45), and the specificity was 97% (95% CI 90-99). In the subgroup analysis, the sensitivity of ESN for PE with high or intermediate-high risk was 69% (95% CI 49-85), and the specificity was 90% (95% CI 84-94). Inter-rater reliability for ESN finding between the cardiologist and emergency physician was strong with a kappa statistic of 0.87., Conclusion: The pulmonary Doppler flow of ESN was moderate to high specific but low sensitive for PE in all ED patients. In the subgroup analysis, this finding was moderate specific and low sensitive., (© 2021 American Institute of Ultrasound in Medicine.)
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- 2022
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15. Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients.
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Surme S, Tuncer G, Copur B, Zerdali E, Nakir IY, Yazla M, Bayramlar OF, Buyukyazgan A, Cinar ARK, Balli H, Kurekci Y, Pehlivanoglu F, and Sengoz G
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- Adolescent, Adult, Aged, Aged, 80 and over, Blood Cell Count, COVID-19 blood, COVID-19 diagnostic imaging, COVID-19 virology, Female, Humans, Male, Middle Aged, Radiography, Retrospective Studies, SARS-CoV-2 classification, SARS-CoV-2 genetics, SARS-CoV-2 isolation & purification, Thorax diagnostic imaging, Tomography, X-Ray Computed, Young Adult, COVID-19 diagnosis
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Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID-19 patients had higher percentages of close contact with a confirmed or probable case. In univariate analysis, the presence of myalgia and dyspnea, decreased leukocyte, neutrophil and platelet counts were best predictors for SARS-CoV-2 RT-PCR positivity. Multivariate analyses revealed that only platelet count was an independent predictor for SARS-CoV-2 RT-PCR positivity. Conclusion: Routine complete blood count may be helpful for distinguishing COVID-19 from other respiratory illnesses at an early stage, while PCR testing is unique for the diagnosis of COVID-19.
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- 2021
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16. Predictors of Intensive Care Unit Admission or Mortality in Patients with Coronavirus Disease 2019 Pneumonia in Istanbul, Turkey.
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Surme S, Buyukyazgan A, Bayramlar OF, Cinar AK, Copur B, Zerdali E, Tuncer G, Balli H, Nakir IY, Yazla M, Kurekci Y, Pehlivanoglu F, and Sengoz G
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- Adult, Aged, COVID-19 diagnosis, COVID-19 mortality, Female, Hospital Mortality, Humans, Male, Middle Aged, Prognosis, Retrospective Studies, Risk Factors, SARS-CoV-2, Turkey epidemiology, COVID-19 epidemiology, Hospitalization statistics & numerical data, Intensive Care Units statistics & numerical data
- Abstract
We aimed to determine the predictors of intensive care unit (ICU) admission or death in patients with coronavirus disease 2019 (COVID-19) pneumonia. This retrospective, single-center study included patients aged ≥18 years who were diagnosed with COVID-19 pneumonia (laboratory and radiologically confirmed) between March 9 and April 8, 2020. The composite endpoint was ICU admission or in-hospital mortality. Univariate and multivariate logistic regression analyses were performed to evaluate the factors associated with the composite endpoint. A total of 336 patients with COVID-19 pneumonia were evaluated. The median age was 54 years (interquartile range: 21), and 187 (55.7%) were men. Fifty-one (15.2%) patients were admitted to the ICU. In-hospital mortality occurred in 33 patients (9.8%). In the univariate analysis, 17 parameters were associated with the composite endpoint, and procalcitonin had the highest odds ratio (odds ratio [OR] = 36.568, confidence interval [CI] = 5.145-259.915). Our results revealed that body temperature (OR = 1.489, CI = 1.023-2.167, P = 0.037), peripheral capillary oxygen saturation (SpO2) (OR = 0.835, CI = 0.773-0.901, P < 0.001), and consolidation (> 25%) on chest computed tomography (OR = 3.170, CI = 1.218-8.252, P = 0.018) at admission were independent predictors. As a result, increased body temperature, decreased SpO2, a high level of procalcitonin, and degree of consolidation on chest computed tomography may predict a poor prognosis and have utility in the management of patients.
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- 2021
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17. National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19.
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Tuncer G, Surme S, Bayramlar OF, Karanalbant HK, Copur B, Yazla M, Zerdali E, Nakir IY, Cinar AR, Buyukyazgan A, Balli H, Kurekci Y, Simsek-Yavuz S, Sonmez MM, Sengoz G, and Pehlivanoglu F
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- Albumins metabolism, Hospital Mortality, Humans, Lymphocytes metabolism, Neutrophils metabolism, Odds Ratio, COVID-19 metabolism, Procalcitonin metabolism
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Aim: We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters during the first week of COVID-19. Materials & methods: All adult patients who were hospitalized for confirmed COVID-19 between 11 March and 11 May 2020 were retrospectively included. Results: Overall, 611 patients were included. Our results showed that NEWS2, procalcitonin, neutrophil/lymphocyte ratio and albumin at D0, D3, D5 and D7 were the best predictors for clinical deterioration defined as a composite of ICU admission during hospitalization or in-hospital death. Procalcitonin had the highest odds ratio for clinical deterioration on all days. Conclusion: This study provides a list of several laboratory parameters correlated with NEWS2 and potential predictors for clinical deterioration in patients with COVID-19.
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- 2021
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18. Comparison of standard prophylactic and preemptive therapeutic low molecular weight heparin treatments in hospitalized patients with COVID-19.
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Copur B, Surme S, Sayili U, Tuncer G, Zerdali E, Yazla M, Nakir IY, Buyukyazgan A, Kurt-Cinar AR, Balli H, Kurekci Y, Pehlivanoglu F, and Sengoz G
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- Heparin, Hospitalization, Humans, Male, Middle Aged, Retrospective Studies, Anticoagulants administration & dosage, COVID-19 therapy, Heparin, Low-Molecular-Weight administration & dosage
- Abstract
Ntroduction: Anticoagulant treatment approach in patients with COVID-19 is not well studied and not standardized. We aimed to compare the effects of standard prophylactic and pre-emptive therapeutic Low-Molecular-weight Heparin (LMWH) treatment approaches on mortality in patients with COVID-19., Patients and Methods: This retrospective and single-centre study includes patients aged ≥ 18 years, who were diagnosed with COVID-19 and treated with LMWH during the hospital stay. Therapeutic dose of LMWH was defined as 1 mg/kg subcutaneously twice daily and prophylactic dose of LMWH was defined as 40 mg subcutaneously once daily., Results: Among the 336 patients diagnosed with COVID-19 pneumonia, 115 patients, who received LMWH were included in the study. The mean age was 58.6 ± 13.3 and 58 (50.4 %) of the patients were male. Sixty-nine (60 %) of the patients were treated with prophylactic and 46 (40 %) therapeutic LMWH.In-hospital mortality was not different between patients treated therapeutic LMWH and prophylactic LMWH by the multivariate regression analysis (OR=2.187, 95% CI 0.484-9.880, p=0.309) and the propensity score modelling (OR=1.586, 95% CI 0.400-6.289, p=0.512.)CONCLUSION: Clinicians should consider the potential risks and benefits of standard prophylactic and pre-emptive therapeutic LMWH. Therefore, anticoagulant therapy should be individualized in patients with COVID-19 (Tab. 3, Ref. 28).
- Published
- 2021
- Full Text
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19. Trends in medical students' career choice of emergency medicine: A 14-year study.
- Author
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Bildik F, Aslaner MA, Kılıçaslan İ, Keleş A, Aksu ŞH, Yazla M, Karamercan MA, and Demircan A
- Abstract
Introduction: The long-term trends of medical students' choice for emergency medicine (EM) in Turkey are unclear. With this background, we aimed to determine the change in the rate of EM preferences of students over the years., Methods: This was a cross-sectional study originated from 6
th -year medical students' feedback forms, to examine trends of EM carrier preferences between 2005 and 2018 in a tertiary care academic emergency department. There are two main questions containing "would you choose EM as a specialty?" and "why?" as open-ended questions in the form. The answers to the open-ended question were classified as six main factors, which were perception of work, lifestyle, nature of work, personal job preference, mentorship/department experiences, and income., Results: During the study, 2957 forms (80.6% of 3668) were completed by 6th -year medical students. Of the students, 26.5% ( n = 784) responded "yes" to the question, which was "would you choose EM as a specialty?," 6.1% ( n = 181) responded "do not know," and 67.4% ( n = 1992) responded "no." In 2005, 15% of students stated that they would choose EM, while this rate increased to 29% in 2018 ( χ2 : 9.67; P trend = 0.003). Perception of work was the most common reason for "yes" (46.3%), "no" (46%), and "do not know" answers., Conclusion: The rate of EM choice of medical students doubled during the study, and approximately one in three students stated that they could choose EM as their future career in the past year. Perception of work was the main factor for choosing or rejecting to EM., Competing Interests: Conflicts of interest None declared., (Copyright: © 2020 Turkish Journal of Emergency Medicine.)- Published
- 2020
- Full Text
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