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Your search keyword '"Ye, Xiao-zhou"' showing total 3 results
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3 results on '"Ye, Xiao-zhou"'

2. Ecosystem stability and its relationship with biodiversity

Author

LI Zhou-Yuan, YE Xiao-Zhou, and Wang Shao-Peng

Subjects
Ecological stability, Ecology, Resistance (ecology), business.industry, Environmental resource management, Biodiversity, Environmental science, Plant Science, business, Resilience (network), Ecology, Evolution, Behavior and Systematics
Published
2021

3. [Synthesizing A beta(1-15) multiple antigen peptide vaccine by indirect conjugation and its immunological activity].

Author

Yang XS, Wang HQ, Yao ZB, Ye XZ, Wu JM, and Zou AG

Subjects
Amino Acid Sequence, Animals, Antibody Specificity, Chromatography, High Pressure Liquid, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, Mice, Mice, Inbred C57BL, Molecular Sequence Data, Peptides chemistry, Vaccines, Subunit chemistry, Peptides chemical synthesis, Peptides immunology, Vaccines, Subunit chemical synthesis, Vaccines, Subunit immunology
Abstract

Aim: To explore the method of synthesizing the A beta(1-15) multiple antigen peptide (MAP) vaccine and to identify its quality and the immunological activity., Methods: MAP A beta(1-15) was synthesized by indirect conjugation and analyzed by RP-HPLC,SDA-PAGE and amino acid analysis. Then, C57BL/6 mice were immunized with synthesized MAP A beta(1-15). The specific anti-A beta antibody in the sera of the immunized mice was identified by ELSA., Results: There was a high and wide peak wave in the RP-HPLC chromatogram. The 8 protein bands identified by SDA-PAGE was identical with 1 to 8 branch of MAP A beta(1-15). The amino acid sequence of synthesized MAP A beta(1-15) was almost similar with the standard. High titer of anti A beta antibody was obtained in the C57BL/6 mice immunized with MAP A beta(1-15)., Conclusion: MAP A beta(1-15) could be synthesized successfully by indirect conjugation and the synthesized MAP A beta(1-15) had satisfactory immune activity. But the purification of the synthesized complex remained to be a problem.

Published
2007

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