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Background and Objective Surgery is the treatment of choice for growth hormone (GH)-secreting pituitary adenoma. The remission of random GH depends on various factors. We aimed to evaluate the predictors related to remission of random GH following surgical treatment. Methods We collected the data retrospectively from the chart review from a single unit of neurosurgery. The diagnostic criteria for remission were a random GH < 1 ng/mL or nadir GH < 0.4 ng/mL after an oral glucose tolerance test. Results Data from a total of 110 (females 62 [56.4%]) patients were available for follow-up and were analyzed. The mean age was 36.5 years (14–69 years). Vision impairments were seen in 39 (35.5%) patients. The mean duration of symptoms before surgery was 34 months. The mean volume of the tumor was 7.2 mL (0.44–109.8 mL). Knosp grade 3 and 4 tumors were seen in 41.5% of cases. The mean preoperative random GH level was 68.9 ng/mL. Transsphenoidal surgery was done in 107 (97.3%) cases. The gross total resection could be done in 36 (32.7%) cases. At 3 months, 25 (26%) patients had a biochemical remission. In univariable analysis, lower Knosp grade, preoperative GH level < 40 ng/mL, gross total resection, and male gender were associated with remission at 3 months. In regression analysis, preoperative GH and male gender were related to remission at 3 months. Conclusion The preoperative GH level < 40 ng/mL is associated with higher chances of remission after surgery for GH-secreting pituitary adenoma. [ABSTRACT FROM AUTHOR]

Byline: Ujwal. Yeole, Vikas. Singh, Prakash. Shetty, Aliasgar. Moiyadi Background and Introduction: Intraoperative ultrasound imaging can be a multi-dimensional tool with various applications, including localization, resection control, and biopsy of [...]

Byline: Ujwal. Yeole, Shantala. Hegde, Mohit. Gothwal, A. Prabhuraj, Sampath. Somanna, K. Thennarasu, Arivazhagan. Arimappamagan Purpose: The health-related quality of life (HRQoL) is an important endpoint in modern clinical practice [...]

Byline: Ujwal. Yeole, Dhaval. Gohil, Dhaval. Shukla, Suparna. Bhardawaj Background and Introduction: Intraoperative neuromonitoring for eloquent cortical lesions is irreplaceable in present-day neurosurgery. Objective: We report a novel technique of [...]

This study evaluated the effect of Position-Specific Physiotherapy Training on Agility, Speed endurance, and Balance in Indian Football Players. Around 70 football players were approached of which 48 gave consent to participate, and further 30 players sufficing inclusion criteria were recruited. They were divided into three groups, Forwards (Group A, n = 10), Defenders (Group B, n = 10), and Control (Group C, n = 10), according to their On-field Position. These participants underwent Position Specific Physiotherapy Training for 4 weeks. Significant improvement was noted in the Agility of Group A (p ≤ 0.001) and Group B (p ≤ 0.001) as compared to Group C (p = 0.071). Speed Endurance improved for Group A (p ≤0.001) and Group B (p ≤ 0.001) as compared to Group C (p = 0.111). Fatigue Index of Group A (p ≤ 0.001) and Group B (p ≤ 0.001) improved significantly as compared to Group C (p = 0.383). The Balance of Group A (p = 0.0063) and Group B (p = 0.0019) improved significantly as compared to Group C (p = 0.0632). Position-Specific Physiotherapy Training was found to be effective in improving Agility, Speed endurance, and Balance ability of the Indian Football Players. [ABSTRACT FROM AUTHOR]

Byline: Ujwal. Yeole, Bhaskara. Malla, A. Arivazhagan, Abhinith. Shashidhar, Harsh. Deora, Ravindranadh. Mundalamuri, K. Raghvendra, Rose. Bharath, Sanjib. Sinha Sir, The commonest cause of spontaneous subarachnoid hemorrhage (SAH) is an [...]

Introduction  Gamma Knife radiosurgery (GKRS) is an effective treatment for benign vestibular schwannomas (VSs). The established cutoffs have recently been challenged, as recent literature expanded the horizon of GKRS to larger tumors. Even though microsurgery remains the primary option for large VS, GKRS can provide reasonable tumor control and is more likely to avoid cranial neuropathies associated with open surgery. Methods  We analyzed patients with VS with volume exceeding 10 cm 3 who underwent GKRS at our center from January 2006 to December 2016. Clinicoradiological and radiosurgical data were collected from medical records for statistical analysis. Follow-up was performed every 6 months with a clinical assessment along with magnetic resonance imaging (MRI) of the brain and audiometric evaluation in patients with serviceable hearing. Results  The study included 34 patients (18 males and 16 females) with an average age of 45.5 years. The mean tumor volume was 10.9 cm 3 (standard deviation [SD], ± 0.83), with a median tumor dose of 12 Gy (interquartile range, 11.5–12) and a mean follow-up of 34.7 months (SD, ± 23.8). Tumor response was graded as regression in 50%, stable in 44.1%, and increase or GKRS failure in 2 cases (5.8%). Treatment failure was noted in five cases (14.7%), requiring microsurgical excision and a ventriculoperitoneal shunt post-GKRS. The tumor control rate for the cohort is 85.3%, with a facial preservation rate of 96% (24/25) and hearing loss in all (5/5), while three patients developed new-onset hypoesthesia. We noted that gait ataxia and involvement of cranial nerve V or VII at initial presentation were associated with GKRS failure in univariate analysis. Conclusion  Microsurgery should remain the first-choice treatment option for large VSs. GKRS is a viable alternative with good tumor control and improved or stabilized cranial neuropathies with a low complication rate. [ABSTRACT FROM AUTHOR]

Byline: Ujwal. Yeole, Ankita. Chand, Biplab. Nandi, Pravin. Gawali, Roshan. Adkitte Purpose: To find out the current physiotherapy practices in Intensive Care Unit (ICU) across Maharashtra. Materials and Methods: Study [...]

Background: As Basketball requires high level conditioning abilities, it is necessary to have the arm and leg explosive power and agility to be derived at desired level. To achieve this derivation we have postulated the Dynamic Neuromuscular exercise training program for Basketball players. This could be useful to enhance their performance by improving their abilities. Aim: To study Effect of Dynamic Neuromuscular Exercise Training on Explosive arm strength and agility in Basketball Players. Setting and Design: Ethical approval was obtained from Institutional ethical committee. Subjects were selected by convenient sampling method. The players were evaluated for Agility and explosive arm stregth. A survey among 68 players was done among which 60 patients participated based on inclusion criteria which were divided into two groups. Methods and Material: Experimental group (Group A, n=30) received Dynamic Neuromuscular Exercise Training Program for 4 days/week for 6 weeks whereas control group (Group B, n=30) received the conventional exercises. Pre and post treatment analysis was recorded using Illinois agility test and Medicine ball throw test. Statistical Analysis: Data was subjected to Shapro-Wilk test which showed data does not pass normality test hence parametric pair and un-paired t test were performed to analyse the data within the groups. Result: Between group comparisons; group A (n=30, mean age= 21.37±2.12) showed extremely significant (p<0.0001), improvement in Medicine ball throw test in pre (5.80±0.88) to post intervention (8.15±0.80) than group B(n=25, mean age=22.9±2.41) in pre (5.9±1.01) to post intervention (6.35±0.97). As well the Illinois agility test showed significant improvement (p<0.0001) in group A (pre= 21.9±2.9 to post=17.85±1.6) than group B (pre=23.35±2.07to post=22.67±2.10).Conclusion: Study concluded that there is significant effect of Dynamic Neuromuscular training on explosive arm strength and agility in basketball players. [ABSTRACT FROM AUTHOR]

BACKGROUND: The judo is the dynamic, high-intensity intermittent sport which needs advanced skills and military science excellence for fulfillment. Throughout the judo combat, strength and muscle power are associated with performance and judo-throw potency; therefore, the study aims to analyze the effect of physiotherapy exercises on grip strength, aerobic performance, and muscular endurance in Indian judo players. MATERIALS AND METHODS: An experimental study design was used. The study participants were divided into two groups: Group A (n = 15) received physiotherapy exercises of grip strength training, muscular endurance training, and aerobic training for 3 days/week for 6 weeks and Group B (n = 15) received the conventional exercise program. Pre- and posttreatment analysis was recorded and statistically analyzed. RESULTS: A total of thirty players were recruited for the study. The grip strength of Group A improved from 13.98 to 19.28 (0.0001) for the dominant hand and from 10.66 to 16.26 (0.0001) for nondominant hand as compared to Group B from 12.92 to 13.59 (0.270) for the dominant hand and from 10.45 to 11.34 (0.135) for nondominant hand. The muscular endurance for sit-ups and push-ups of Group A improved from 10.2 to 17.2 (0.0001) and 13.47 to 19.93 (0.0001), respectively, as compared to Group B whose values were 9–10.13 (0.091) and 11.67–12.53 (0.155), respectively. The aerobic performance of Group A improved from 40.91 to 47.31 (0.0001) as compared to Group B from 39.26 to 40.16 (0.222). CONCLUSION: Physiotherapy exercises are effective for improvement in grip strength, aerobic performance, and muscular endurance among Indian judo players. [ABSTRACT FROM AUTHOR]

Background: Diabetes mellitus, a chronic noncommunicable disease, is associated with long-term damage of multiple organ system with its long-term complications and significantly impacts upon the quality of life (QoL) of affected patients. Methods: A survey was carried out on 245 patients during thirty sessions of diabetes outpatient department at multispecialty hospitals, among which 228 patients agreed for the participation. A final survey was carried on 200 patients, whereas 28 patients did not fit into the criteria. Further evaluation was carried out using the World Health Organization QoL-BREF questionnaire in Hindi, English, and Marathi versions. The mean score and total score of domains were calculated to check the QoL of the patients. Results: Almost 72% of the participants mentioned good QoL in physical domain with 18% mentioning average QoL. Around 35% mentioned excellent QoL in psychological domain with 46% mentioning good QoL. Around 55% mentioned good QoL in social domain. Majority of participants mentioned good (23%) to excellent (71%) QoL in environmental domain. The physical domain demonstrated a mean score of 66.6 ± 9.303 (min 44, max 94). The psychological domain demonstrated the mean score of 70.9, ±15.558, (min 5, max 94). The social domain demonstrated the mean score of 75.96, ±15.245, (min 31, max 100). The environmental domain demonstrated the mean score of 82.19, ±13.211, (min 31, max 100). Conclusion: Overall patients mentioned average-to-good QoL in physical, psychological, and social domain, and a majority of patients had good QoL in environmental domain. [ABSTRACT FROM AUTHOR]

Background :Badminton is a popular worldwide sport that requires fast and powerful shots and agile footwork. It is one of the fastest racket sports in the world. [1]The agility and vertical jump are important motor skills to hit a shuttlecock at different positions around the court. Objectives: To see the effect of plyometric training on jumping performance and agilityin badminton players.Methodology: 30 participants, both male and female were included in this study. All participants were tested for agility and vertical jump before and after 6-weeks plyometric training period. Agility performance was assessed using Agility T-Test and vertical jump height was assessed using vertical jump test. The participants performed plyometric training thrice a week, for 6 weeks.Results:The data was collected and statistically analysed using paired t test.The study concluded that there was an increase in vertical jump height(40.37±7.690cm) and agility (11.74±1.366sec) post plyometric training with significant p value (<0.0001).Conclusion:Our results show that six weeks plyometric training improved jumping performance and agility in badminton players. [ABSTRACT FROM AUTHOR]

Background: Dancing involves high as well as moderate impact activities, interplay between aesthetic and physical demands which collectively increases intra-abdominal pressure responsible for stress urinary incontinence in female dancers. Practicing Kegel's and Behavioural Intervention therapy can minimize severity of problem. Objectives: To find out effectiveness of Kegel's exercises, Behavioural intervention therapy and combination of both on stress urinary incontinence in female dancers using IIQ and Pad test Methodology: Permission was taken from institutional ethical committee. 90 female dancers were assessed using QUID and dancers having stress urinary incontinence aged 18-25 years; practicing since 5 years were selected. Pre intervention evaluation was followed by Kegel's exercise for Group A, behavioral intervention therapy for Group B and combination of Kegel's exercise along with behavioral intervention therapy for Group C. Post intervention assessment was carried out. Results: Data was statistically analyzed using Wilcoxon test for within the groups and among the groups by using Kruskal-wallis test. IIQ for group A pre-intervention mean was 5.5± 1.45 and post intervention mean was 4.7±1.04 with p <0.00048, For group B pre-intervention mean was 5.8 ± 1.27 and post 5.1± 1.27 with p<0.003 and For group C pre-intervention mean was 5.9±1.18 and post intervention mean was 4.4±0.85 with p<0.0001 which is very significant, while comparing group A B and C IIQ post values p<0.08812 which is not significant. Pad test for group A preintervention mean7.3±1.78 was and post intervention mean was 6.4±1.4 with p<0.0001, For group B preintervention mean was7.5±1.48 and post intervention mean was 6.7±1.44 with p<0.0001, For group C preintervention mean was7.8±1.47 and post intervention mean was 6.2±1.21with p<0.0001 which is significant while comparing group A B and C Pad test post values p<0.08812 which is not significant. Conclusion: Our study concludes the effectiveness of various Physiotherapy interventions within the groups and all interventions being equally effective. [ABSTRACT FROM AUTHOR]

Background: Parkinson's disease is a chronic, progressive and neurodegenerative disorder. A range of motor and non-motor symptoms may cause postural instability and impaired functional mobility often leading to falls and decrease quality of life. Physical therapy with Music therapy may be promising intervention to improve gait and related activities in Parkinson's disease. Methodology: Permission was taken from institutional ethical committee. An experimental study was conducted on 30 individual selected on the basis of inclusion and exclusion criteria. Randomized allocation of the participants was done into experimental (Physical therapy with music therapy) and control (Conventional physical therapy) groups. Participants were evaluated pre and post intervention for gait using Dynamic gait index (DGI), balance using Time up and go (TUG) and quality of Life using Parkinson's disease quality of life 39 (PDQ 39) questionnaire. A six weeks intervention program was given to the patients for four times per week. Result: Data was analyzed using Shapiro-wilk test accordingly parametric or non- parametric test were performed. Between groups comparisons showed extremely significant (p<0.001) improvement on DGI (4±1.363), TUG test (2±0.92) and PDQ 39 questionnaire (45.07±10.62) in experimental group as compare to DGI (2.33±1.496), TUG test (0.933±0.70) and PDQ 39 questionnaire (42.53±10.56) in control group. Conclusion: The study concluded that physical therapy with Music therapy is effective in improving gait, balance and quality of Life in patients with Parkinson's disease. [ABSTRACT FROM AUTHOR]

Background: The patient's awareness about diabetes, its complications, role of lifestyle modifications can establish patient specific goals. This study was done to determine the level of awareness regarding Diabetes mellitus, its complications and Glycemic control. Methods: A survey was carried out on 245 diabetic patients visiting Medicine OPDs at affiliated hospitals in Pune to determine the level of awareness of Diabetes Mellitus and Glycemic control amongst patients with Type 2 Diabetes. A predesigned and validated questionnaire was administered which was further modified post pilot study. Results: Total 200 patients with mean age of 53±6.66 years (84 males and 116 females), mean duration of diabetes 8.20±8.057 years and mean HbA1C 7.11±0.95 % were interviewed for the level of awareness of Diabetes Mellitus and Glycemic control. Around 62% people perceived diabetes to be a life lasting disorder whereas 24% considered it to be a life threatening and a non-treatable disorder. Almost 77% completely agreed that Glycemic control is important with 71% completely agreed that daily exercise with a particular exercise regime and lifestyle modification proves advantageous. Around 63% completely agreed that a proper diet plan should be followed by diabetics and they should not skip meals. Conclusion: Majority of diabetes patients had awareness about diabetes, its complications, role of exercises and diet in glycemic control. [ABSTRACT FROM AUTHOR]

Background: Taekwondo is a technique of unarmed self-defense that involves skillful application of techniques which include punching, jumping, kicks, blocks and dodges. Beside speed, response to the opponent's actions along with good balance appear to be key elements for victory. Hence a good balance is required for excellent performance with minimal injuries Method: A total of 60 players were selected based on inclusion and exclusion criteria. The aim and objectives of the study were explained to them and their written consent was taken. Balance was assessed using single legged stance test and community balance and mobility scale. The players were divided into two groups of 30 players each. A four week intervention program consisting of dynamic postural control activities was given to the players in group Athrice a week for four consecutive weeks and those in group B received conventional exercises including stretching and drilling. The pre and post values were recorded on 1st and 12th day respectively and the data obtained was statistically analyzed. Results:The average CBM scale score before intervention were 74/96 in group A and 72/96 in group B. These were improved to an average of 91.2/96 and 80.32/96 in group A and group B respectively after intervention showing a value of p<0.0001. Also, significant improvement is seen in single legged stance test scores in group A as compared to group B. Conclusion: Dynamic postural control activities are effective in improving the balance thereby improving the performance in amateur Indian Taekwondo players. [ABSTRACT FROM AUTHOR]

Background- In patients with diabetes upper extremity impairments are common. Diabetes patient are more prone to diabetic hand. Aim- To study the effect of hand exercises on hand grip strength and manual dexterity in patients with Diabetic hand .Objectives- To study the effect of hand exercises on hand grip strength in patients with Diabetic hand using Modified sphygmomanometer test. To study the effect of hand exercises dexterity in patients with Diabetic hand using grip ability scale. To study the effect of hand function in patients with Diabetic hand using Michigan hand outcomes questionnaire (MHQ) and Duruoz Hand Index. Setting and design - In this study 15 individual participated having diabetic hand which was selected randomly. Modified sphygmomanometer test was performed on patient to check grip strength. Grip ability scale was performed on patient to check manual dexterity. Hand function was check using Michigan hand outcomes questionnaire (MHQ) and Duruoz Hand Index. The effect of hand exercise on hand grip strength and manual dexterity in patients with diabetic hand was analysied. Result- Total 15 individual participated with age mean 58±13.519 and duration of diabetes with mean 11±6.448. Modified sphygmomanometer test result improved from 28.13±3.044 to 32.47±2.875(p=0.001). Grip ability test result improved from 23.13±3.523 to 18.67±1.345(p=0.001). Michigan hand outcome questionnaire result improved from 53.29±10.19 to 71.34±5.036(p=0.001). Duruoz Hand Index result improved from 31.67±11.2 to13.47±4.596(0.001).Conclusion- There is significant effect of hand exercises on hand grip strength and manual dexterity in patient with diabetic hand. [ABSTRACT FROM AUTHOR]

Background: Tennis Elbow is the most common overuse syndrome in the elbow. It is a tendinopathy injury involving the extensor muscles of the forearm. The lateral epicondylitis is characterized by pain and tenderness at the lateral epicondyle of the humerus as there is non-specific inflammation at the origin of the extensor muscles of forearm. As there is pain and inflammation, the grip strength in decreased and hand function is affected. But there are few research done on intervention regarding same. Hence a comparative study was carried on 60 patient, 30 subjects were grouped in Group A which were given functional task exercises and Group B was given Conventional therapy. The stastical analysis showed that out of 30 subjects, mean age of group A patients was 25±6.23 and mean age of group B patients was 27.2±4.8. Grip strength in between Group A (63.5± 14.2) and Group B (60.4± 12.9) with p value 0.04, Patient rated tennis elbow evaluation scale in between Group A (44.1± 6.8) and Group B (43.8±10.6) with p value 0.002 and Michigan hand outcome measures in between Group A (62.5±14.4) and Group B (54.3±14.7) with p value 0.0005. Hence the study concluded that there is significant effect of Functional Task Exercises on Grip strength and Hand function in lateral epicondylitis. [ABSTRACT FROM AUTHOR]

Background: Diastasis recti is a separation of rectus abdominis muscles in the midline at the linea alba. Diastasis recti may occur in pregnancy as a result of hormonal effects on the connective tissue and the biomechanical changes of pregnancy.The kinesio taping results shows increased fluid flow through an injured area, better control over muscle contractions, reduced pain, and ultimately faster healing. Methodology: Permission was taken from institutional ethical committee. Subjects were selected by convenient sampling method. Patients were evaluated pre and post for diastasis recti using finger-width test and for disability assessed by using modified oswestry disability index. Result: The analyzed data showed that it was not a normal distribution using shapro -Wilk test hence Non parametric test-Wilcoxon sign rank test was performed to analyze the data within the groups. Diastasis recti of group A above umbilicus level pre-intervention mean was 3.040+0.4643 and post-intervention mean was 0.2350+0.3986. At umbilicus level pre-intervention mean was 3.100+0.3482 and post-intervention mean was 0.2950+0.4026and below umbilicus level pre-intervention mean was 2.435+0.4802 and post-intervention mean was 0.035+0.1466. In group B above umbilicus level pre-intervention mean was 2.965+0.5088 and post-intervention mean was 0.365+0.4542. At umbilicus level pre-intervention mean was 3.215+0.4988 and post-intervention mean was 0.4100+0.4626 and below umbilicus level pre-intervention mean was 2.115+0.5461 and post-intervention mean was 0.1350+0.3397. Comparison between the groups was done using Mann-Whitney U Test above umbilicus p value is 0.0059 which is very significant, at umbilicus p value is 0.9072 which is not significant, below umbilicus p value is 0.1124 which is not significant. Conclusion: Our study shows that kinesio taping with exercise shows greater effect on diastasis recti than only exercises in post-partum women. [ABSTRACT FROM AUTHOR]

Background: Cancer patients undergone chemotherapy or radiotherapy reports cancer-related fatigue(CRF), which impairs their aerobic capacity and quality of life (QOL). Aim: To study the effect of physiotherapeutic exercises on fatigue and quality of life in cancer patients. Setting and Design: Ethical approval was obtained from Institutional ethical committee. The cancer patients visiting affiliated cancer rehabilitation centers at Alandi were assessed by oncologist and referred for physiotherapy. The patients were evaluated for fatigue and quality of life (Total 64 patients). Patient satisfying inclusion criteria and who willing to participate in study were recruited and further randomly allotted in two groups using Random sampling method. Methods and Material: Experimental group (Group A, n=25) received home based aerobic exercise program for 3 days/week for 4 weeks whereas control group (Group B, n=25) received the individually tailored walking program. Pre and post treatment analysis was recorded using Modified Fatigue Impact Scale and SF-36 Questionnaire. Statistical Analysis: The Analysed Data showed normal distribution using Shapro-Wilk test, hence parametric Whitney Rank Sum Test was performed to analyse the data within the groups. Result: Total 50 patients participated in study. Between group comparisons; group A (n=25, mean age= 44.40±9.92) showed extremely significant (p<0.0001), improvement in Modified Fatigue Impact Scale (MFIS) in pre (44.56 ± 9.36) to post intervention (35.16±7.526) than group B(n=25, mean age=51.76±13.47) in pre (44.24 ±8.57) to post intervention (50.68±7.034).As well Quality of life of cancer patients underwent treatment has been significantly improved (p<0.0001) in group A (pre= 62 to post=67.52) than group B (pre=.63.94 to post=63.08). Conclusion: It is concluded that aerobic training showed greater impact on fatigue and quality of life in cancer patients. [ABSTRACT FROM AUTHOR]

Background: Diabetic patients are considered to be more prone to develop cognitive dysfunction and further leading to dementia, hence systematic assessment and identification of risk factors plays a key role. Aim and objectives: To study cognitive impairments and its associated risk factors among patients with diabetes mellitus . Settings and Design: A hospital-based Multicentre cross-sectional study was conducted. Methods and Material: In this study 245 individual medically diagnosed to have diabetes mellitus were recruited according to inclusion and exclusion criteria. Demographic data included age gender and duration of diabetes smoking, BMI, Family history of diabetes and Hypertension HbA1c was noted. Cognitive assessment was done using Modified Mini Mental Scale (3MS). Data was collected and subjected to statistical analysis. Results: The result shows about 22% had moderate cognitive impairment and associated risk factors can be medications, age, glycaemic control, Hypertension, family history. There is no correlation of Cognition and duration since diagnosed to be diabetic and BSL whereas weak linear relationships exist between cognition and Age and HbA1c and strong linear relationship between cognition and BMI in Patients with diabetes. Conclusions: Diabetic patients do exhibit Mild cognitive dysfunction with various associated risk factors. [ABSTRACT FROM AUTHOR]