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2 results on '"Yeping Wei"'

1. Endometrial large cell neuroendocrine carcinoma: A case report and literature review

Author

Feng Yang, Shoujun Liang, Chuanzhong Liu, Yeping Wei, and Liying Zhang

Subjects
Large cell neuroendocrine carcinoma, Endometrium, Immunohistochemistry, Gynecology and obstetrics, RG1-991, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Endometrial large cell neuroendocrine carcinoma (LCNEC) is a highly malignant tumor that presents with neuroendocrine function. It is difficult to diagnose at an early stage. Moreover, the diagnosis depends on the pathological and immunohistochemical findings. It is also prone to distant metastasis, but is difficult to treat and shows poor prognosis. Presently, there exists no unified treatment plan, and the prognosis of this disease is also poor. We reported here an analysis and literature review of a case of endometrial LCNEC to facilitate the comprehension of this disease and provide help toward clinical diagnosis and treatment.

Published
2024
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2. Characterization and anti-allergic effect of a polysaccharide from the flower buds of Lonicera japonica

Author

Jing Tian, Huilian Che, Yeping Wei, Shu-yun Zheng, and Da Ha

Subjects
Chromatography, Gas, Polymers and Plastics, Stereochemistry, Prednisolone, Anti-Inflammatory Agents, Administration, Oral, Flowers, Picryl Chloride, Polysaccharide, Immunoglobulin E, Methylation, Picryl chloride, chemistry.chemical_compound, Mice, In vivo, Polysaccharides, Anti-Allergic Agents, Materials Chemistry, medicine, Animals, Allergic contact dermatitis, Caprifoliaceae, chemistry.chemical_classification, Mice, Inbred ICR, biology, Tumor Necrosis Factor-alpha, Organic Chemistry, Body Weight, Biological activity, Ear, medicine.disease, biology.organism_classification, Molecular biology, Molecular Weight, stomatognathic diseases, Lonicera, chemistry, Dermatitis, Allergic Contact, biology.protein, Female, Histamine
Abstract

A water-soluble polysaccharide (LJP-1), with a molecular weight of 1.8×10(5) Da, was isolated from the flower buds of Lonicera japonica. Gas chromatography (GC) analysis showed that the LJP-1 was mainly composed of d-glucose and a small amount of d-arabinose. On the basis of methylation analysis, LJP-1 had the backbone chain mainly consisting of 1,6-linked Glc and 1,3,6-linked Glc, which was terminated with 1-linked Ara residues at the O-3 position of 1,3,6-linked Glc in a relative molar ratio of 2.9:1:0.9. The anti-allergic effect of LJP-1 was evaluated on allergic contact dermatitis (ACD) induced by picryl chloride (PC) in mouse ear. Similar to prednisolone, orally administrated LJP-1 (20, 40 and 80 mg/kg) potently inhibited the PC-induced ACD, leading to substantial reductions in ear thickness, serum level of IgE and histamine, as well as tissue TNF-α. These results demonstrate that treatment with LJP-1 may be effective for preventing the development of PC-induced ACD.

Published
2012

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