Search

Your search keyword '"Yip, Kenneth W."' showing total 139 results
Start Over Author "Yip, Kenneth W."
139 results on '"Yip, Kenneth W."'

3. Radiomic Biomarkers to Refine Risk Models for Distant Metastasis in HPV-related Oropharyngeal Carcinoma

Author

Kwan, Jennifer Yin Yee, Su, Jie, Huang, Shao Hui, Ghoraie, Laleh S., Xu, Wei, Chan, Biu, Yip, Kenneth W., Giuliani, Meredith, Bayley, Andrew, Kim, John, Hope, Andrew J., Ringash, Jolie, Cho, John, McNiven, Andrea, Hansen, Aaron, Goldstein, David, de Almeida, John R., Aerts, Hugo J., Waldron, John N., Haibe-Kains, Benjamin, O'Sullivan, Brian, Bratman, Scott V., and Liu, Fei-Fei

Published
2018
Full Text
View/download PDF

21. Additional file 3 of MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma

Author

Pierre-Antoine Bissey, Teng, Mona, Law, Jacqueline H., Shi, Wei, Bruce, Jeff P., Petit, Valentin, Tsao, Sai W., Yip, Kenneth W., and Liu, Fei-Fei

Abstract

Additional file 3: Figure S3. (A) Relative SOX4 and SOX2 expression assessed by qRT-PCR in NP69 cells stably overexpressing SOX4. (B) Relative SOX2 expression assessed by qRT-PCR in C666–1 cells stably expressing pre-miR-34c. (C, D, and E) Cell viability was measured by ATPlite assay 72 h after cisplatin treatment: (C) Stable C666–1-anti-miR-34c (or control) cells. (D) Stable NP69-pre-miR-34c (or control) cells. (E) Stable NP460-pre-miR-34c (or control) cells. (F) Effect of SB431542 on C666–1 cell viability measured by ATPlite at 72 h. The data are represented as the mean ± SEM of at least three independent experiments. * P

Published
2020
Full Text
View/download PDF

22. Additional file 1 of MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma

Author

Pierre-Antoine Bissey, Teng, Mona, Law, Jacqueline H., Shi, Wei, Bruce, Jeff P., Petit, Valentin, Tsao, Sai W., Yip, Kenneth W., and Liu, Fei-Fei

Subjects
stomatognathic diseases, otorhinolaryngologic diseases
Abstract

Additional file 1: Figure S1. (A) Relative miR-34c expression assessed by qRT-PCR in C666–1 cells treated with SB431542 (10 or 20 μM) for 72 h compared to untreated cells (UT). (B and C) Relative expression of putative miR-34c targets assessed by qRT-PCR in NP69, NP460, and C666–1 cells, normalized to C666–1 cells. (B) Genes that are highly expressed in C666–1 (NPC) cells vs. NP69 and NP460 (normal nasopharyngeal) cells. (C) Genes with no significant differences in expression between C666–1 cells and NP69/NP460. Note that MARCKS and PML expression were significant only between C666–1 and NP460 cells. The data are represented as the mean ± SEM of at least three independent experiments. * P

Published
2020
Full Text
View/download PDF

23. Additional file 2 of MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma

Author

Pierre-Antoine Bissey, Teng, Mona, Law, Jacqueline H., Shi, Wei, Bruce, Jeff P., Petit, Valentin, Tsao, Sai W., Yip, Kenneth W., and Liu, Fei-Fei

Abstract

Additional file 2: Figure S2. (A) Relative expression of putative miR-34c target genes after transient transfection with pre-miR-34c (20 or 50 nM; 72 h after transfection) in C666–1 cells. (B) Relative expression of putative miR-34c target genes after SB431542 treatment (10 or 20 μM; 72 h) in C666–1 cells. (C to J) Relative expression of significantly dysregulated genes (ARID5A, BIK, LITAF, NFKBIA, SOX4, BAX, and PML) as assessed by qRT-PCR. (C) Gene expression after transient transfection with pre-miR-34c (20 or 50 nM) in NP69 cells. (D) Gene expression after transient transfection with pre-miR-34c (20 or 50 nM) in NP460 cells. (E) Gene expression of NP69-anti-miR-34c stable cells. (F) Gene expression of NP69-pre-miR-34c stable cells. (G) Gene expression of NP460-anti-miR-34c stable cells. (H) Gene expression of NP460-pre-miR-34c stable cells. (I) Gene expression of C666–1-anti-miR-34c stable cells. (J) Gene expression of C666–1-pre-miR-34c stable cells. The data are represented as the mean ± SEM of at least three independent experiments. * P

Published
2020
Full Text
View/download PDF

27. 85: The Role of Cytokine Signaling in the Reversal of Chronic Lymphedema

Author

Kwan, Jennifer Yin Yee, primary, Xu, Wenxi, additional, Sandhu, Vandana, additional, Demidov, Valentin, additional, Shi, Willa, additional, Vitkin, Alex, additional, Jones, Jennifer, additional, Williams, Justin, additional, Haykal, Siba, additional, Haibe-Kains, Benjamin, additional, Brooks, David G., additional, Yip, Kenneth W., additional, and Liu, Fei-Fei, additional

Published
2020
Full Text
View/download PDF

31. Inflammatory Biomarkers, Hematopoietic Stem Cells, and Symptoms in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy

Author

Shi, Wei, primary, Misra, Shagun, additional, Li, Madeline, additional, Su, Jie, additional, Chong, Lisa P, additional, McCuske, Megan, additional, Williams, Justin, additional, Xu, Wei, additional, Ghoraie, Laleh S, additional, Sutherland, D Robert, additional, Han, Kathy, additional, Minden, Mark D, additional, Bratman, Scott V, additional, Yip, Kenneth W, additional, and Liu, Fei-Fei, additional

Published
2020
Full Text
View/download PDF

40. MiR-449a promotes breast cancer progression by targeting CRIP2

Author

Shi, Wei, primary, Bruce, Jeff, additional, Lee, Matthew, additional, Yue, Shijun, additional, Rowe, Matthew, additional, Pintilie, Melania, additional, Kogo, Ryunosuke, additional, Bissey, Pierre-Antoine, additional, Fyles, Anthony, additional, Yip, Kenneth W., additional, and Liu, Fei-Fei, additional

Published
2016
Full Text
View/download PDF

41. Abstract 5297: Chromosomal instability as a prognostic marker in cervical cancer

Author

How, Christine, primary, Bruce, Jeff, additional, So, Jonathan, additional, Pintilie, Melania, additional, Haibe-Kains, Benjamin, additional, Hui, Angela, additional, Clarke, Blaise, additional, Hedley, David, additional, Hill, Richard, additional, Milosevic, Michael, additional, Fyles, Anthony, additional, Yip, Kenneth W., additional, and Liu, Fei-Fei, additional

Published
2015
Full Text
View/download PDF

49. A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase

Author

Yip, Kenneth W., primary, Zhang, Zhan, additional, Sakemura-Nakatsugawa, Noriko, additional, Huang, Jui-Wen, additional, Vu, Nhu Mai, additional, Chiang, Yi-Kun, additional, Lin, Chih-Lung, additional, Kwan, Jennifer Y. Y., additional, Yue, Shijun, additional, Jitkova, Yulia, additional, To, Terence, additional, Zahedi, Payam, additional, Pai, Emil F., additional, Schimmer, Aaron D., additional, Lovell, Jonathan F., additional, Sessler, Jonathan L., additional, and Liu, Fei-Fei, additional

Published
2014
Full Text
View/download PDF

50. HPV Associated Head and Neck Cancer.

Author

Spence, Tara, Bruce, Jeff, Yip, Kenneth W., and Fei-Fei Liu

Subjects
CARCINOGENESIS, BIOMARKERS, EPITHELIAL cells, HEAD tumors, NECK tumors, PAPILLOMAVIRUS diseases, PAPILLOMAVIRUSES, PROGNOSIS, RNA, SQUAMOUS cell carcinoma, NEOPLASTIC cell transformation, OROPHARYNGEAL cancer, DISEASE complications
Abstract

Head and neck cancers (HNCs) are a highly heterogeneous group of tumours that are associated with diverse clinical outcomes. Recent evidence has demonstrated that human papillomavirus (HPV) is involved in up to 25% of HNCs; particularly in the oropharyngeal carcinoma (OPC) subtype where it can account for up to 60% of such cases. HPVs are double-stranded DNA viruses that infect epithelial cells; numerous HPV subtypes, including 16,18, 31, 33, and 35, drive epithelial cell transformation and tumourigenesis. HPV positive (HPV+) HNC represents a distinct molecular and clinical entity from HPV negative (HPV-) disease; the biological basis for which remains to be fully elucidated. HPV positivity is strongly correlated with a significantly superior outcome; indicating that such tumours should have a distinct management approach. This review focuses on the recent scientific and clinical investigation of HPV+ HNC. In particular, we discuss the importance of molecular and clinical evidence for defining the role of HPV in HNC, and the clinical impact of HPV status as a biomarker for HNC. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results