1. Predictors of Methicillin-resistant Staphylococcus aureus infection in children with acute osteomyelitis
- Author
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Kang Wang, Chen Wang, Hua Zhu, Yan Zou, Yanhua Feng, Fang Zhang, Yi Qu, and Yiren Tian
- Subjects
Acute hematogenous osteomyelitis ,Pediatrics ,Septic arthritis ,Panton–Valentine leucocidin ,RJ1-570 - Abstract
Abstract Background This study aims to identify risk factors associated with Methicillin-resistant Staphylococcus aureus (MRSA) infection in children diagnosed with acute osteomyelitis (AO) and to elucidate the laboratory characteristics of these MRSA-infected children to enhance early targeted therapeutic interventions. Methods We conducted a retrospective analysis involving 123 children with acute osteomyelitis treated at our hospital. Upon admission, we measured white blood cell (WBC) counts, C-reactive protein (CRP) levels, erythrocyte sedimentation rates (ESR), and platelet counts. Patients were categorized into two groups: the non-MRSA group (n = 73) and the MRSA group (n = 50), with values assigned as follows (non-MRSA group = 0, MRSA group = 1). Results The MRSA group had a significantly higher average age compared to the non-MRSA group (P 10.95 × 10^9/L, CRP > 49.56 µg/mL, age > 3.5 years, and the absence of suppurative arthritis suggests a heightened risk of MRSA infection.
- Published
- 2024
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