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After surrounding rock is disturbed by some damage form a loosen circle in surrounding rocks of a roadway, in order to solving the range of loosen circle, mechanical mechanism of loosen circle was discussed on the basis of damage mechanics and loosen circle radius calculation formula proposed. This work has some certain reference for roadway support design.

In this paper use the shield construction of Dalian subway 202 bid section as an example, carried out the monitoring measurement of surface subsidence and crown surface subsidence during the shield construction, detailed analysis the monitoring data, explored the characteristics and distribution of surrounding rock and surface deformation of large cross section shield construction. Construction transverse deformation has a relationship with lateral position and the tunnel excavation length. The closer from shield machine working face, the closer to the center line of the tunnel, the greater impact is. The research results have reference value for the future similar engineering design and construction.

To investigate the expressions of caspase-8, receptor interacting protein (RIP) and nuclear factor (NF)-kappaBp65 in oral lichen planus (OLP) and their relationship with cell apoptosis.Immunohistochemical technique with SP method was used to detect the expressions of caspase-8, RIP and NF-kappaBp65 in 30 OLP cases and 15 normal oral mucosa specimens. Terminal deoxynucleotidyl transferase-mediated nucleotide shift enzyme (TdT) mediated d-UTP end labeling (TUNEL) was used for detecting the cell apoptotic index (AI) in 15 OLP cases and 5 nomal oral mucosa specimens.Compared with the control group, the AI of epithelial cells (6.76 +/- 2.32) increased and the AI of lymphocytes (1.75 +/- 0.74)decreased in OLP (P0.01). The positive rate of caspase-8, RIP and NF-kappaBp65 of epithelial cells were 97% (29/30), 87% (26/30) and 93% (28/30) respectively, significantly higher in OLP than in normal control (P0.05). The positive rate of caspase-8, RIP and NF-kappaBp65 of lymphocytes were 100% (30/30, 90% (27/30) and 80% (24/30) respectively, significantly higher in OLP than in normal control (P0.01). A positive correlation was also observed between NF-kappaBp65 expression of lymphocytes and AI of epithelial cells.Accelerated apoptosis of the keratinocytes and inhibition of lymphocyte apoptosis may coexist and contribute to the formation and progression of OLP. The over expression of caspase-8, RIP and NF-kappaBp65 in OLP may play a role in the pathogenesis of OLP.

To detect the expressions of receptor-interacting protein (RIP) and caspase-8 and investigate their roles in oral squamous cell carcinoma (OSCC) and oral precancerous lesions.SABC immunohistochemical methods were used to detect the expressions of RIP and caspase-8 in 22 specimens of OSCC, 14 specimens of oral lichen planus (OLP), 14 specimens of oral leukoplakia (OLK) and 10 specimens of normal oral mucosa (NOM).The rate of weak or negative expression of RIP in normal mucosa was 50% (5/10). The rates of weak and positive expression of RIP in OLP, OLK and OSCC were 75% (36/50), and the rate of positive and strong expression of RIP was 63.7% (14/22) in OSCC, significantly higher that in the others groups (P0.05). The rates of weak, positive and strong positive expression of caspase-8 in NOM, OLP, OLK and OSCC were 80% (8/10), 100% (14/14), 85.7% (12/14), and 100% (22/22), respectively.Both RIP and caspase-8 may play important roles in the occurrence and progression of OSCC and oral precancerous lesions.

In this paper, landfill leachates and vacuum technique were investigated. Conditions for the removal and reclaim of high content ammonia from landfill leachates were studied by vacuum method; the device made on the spot was used to find the optimal experimental procedures. While the operating time was 1.5 hours, the temperature was of 50degC, a vacuum degree was 1.5 m water column, and the highest removal rate for ammonia could be obtained, but the primary ammonia contents of landfill leachates could hardly influence on the efficiency of ammonia removal. In despite of the same condition , adsorption of ammonia by injector was better than by vacuum pump ,that the methods of adsorption are very important for the reclaim of ammonia was demonstrated by the tests. In the work , both the characteristics without adjusting the pH value of 8.5 , and the reclaiming of ammonia, distinguished from others by special quality.

To observe the clinical efficacy of Huangqi Fuzheng Decoction (HQFZD) in treating recurrent genital herpes (RGH) and its influence on related cytokines in peripheral blood.Eighty-four patients with RGH were randomly assigned to 3 groups, the treated group treated with HQFZD (31 cases), the control group A (25 cases) treated with Aciclovir, and the control group B (28 cases) treated with Aciclovir plus interferon. The course of treatment was 3 weeks for all. The relapse rate was estimated at 6 months after treatment, and levels of IL-4, IL-10, IL-12 and IL-18 in all patients were detected before and after treatment using double-sandwich ELISA.All patients were cured after treatment. The relapse rate in the treated group and the control group B was lower than that in the control group A (P0.01) but insignificant difference was shown between the former two groups. Before treatment, patients' serum levels of IL-4 and IL-10 were significantly higher while those of IL-12 and IL-18 were lower than the normal range (P0.01). The abnormal change aforementioned reversed after treatment in the treated group and the control group B (P0.05 or P0.01), showing a superior effect to that in the control group A (P0.01).HQFZD can reduce the relapse rate of RGH without obvious adverse reaction, and it could also enhance the immunity of the patients.