132 results on '"Yoo, Jakyung"'
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2. Data from A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy
3. Supplementary Table 1 from A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy
4. Computer-aided identification of new histone deacetylase 6 selective inhibitor with anti-sepsis activity
5. Discovery and development of DNA methyltransferase inhibitors using in silico approaches
6. List of Contributors
7. The Road Ahead of the Epi-Informatics Field
8. List of Contributors
9. DNA Methyltransferase Inhibitors for Cancer Therapy
10. Synthesis and biological evaluation of 4(5)-(6-methylpyridin-2-yl)imidazoles and -pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors
11. Structure–activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase
12. Discovery of a novel CDK7 inhibitor YPN-005 in small cell lung cancer
13. Docking of a novel DNA methyltransferase inhibitor identified from high-throughput screening: insights to unveil inhibitors in chemical databases
14. Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase
15. Computer-guided discovery of epigenetics drugs: molecular modeling and identification of inhibitors of DNMT1
16. Molecular Modeling of Inhibitors of Human DNA Methyltransferase with a Crystal Structure
17. Discovery and Optimization of Inhibitors of DNA Methyltransferase as Novel Drugs for Cancer Therapy
18. CASE Plots for the Chemotype-Based Activity and Selectivity Analysis: A CASE Study of Cyclooxygenase Inhibitors
19. Abstract 4849: YPN-005, an oral CDK7 inhibitor, shows a significant antitumor activity in Myc amplified solid tumors and MCL-1 overexpressed blood cancer
20. Methylsulfonylpyrazolyl oxadiazoles and thiadiazoles as potent, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity
21. Abstract 2697: YPN005, an oral CDK7 inhibitor, exhibits a significant antitumor activity in Myc-driven cancers
22. Chapter 15 - The Road Ahead of the Epi-Informatics Field
23. Chemoinformatic Approaches for Inhibitors of DNA Methyltransferases: Comprehensive Characterization of Screening Libraries
24. Dehydroevodiamine•HCl Protects Against Memory Impairment and Cerebral Amyloid-β Production in Tg2576 Mice by Acting as a β-Secretase Inhibitor
25. The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of l,d-Carboxypeptidase
26. Discovery and Optimization of Inhibitors of DNA Methyltransferase as Novel Drugs for Cancer Therapy
27. Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases
28. Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents
29. Antiviral activity of novel 2′-fluoro-6′-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants
30. Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents.
31. Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking
32. Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and Partial Agonists
33. Molecular Modeling Studies of the Novel Inhibitors of DNA Methyltransferases SGI-1027 and CBC12: Implications for the Mechanism of Inhibition of DNMTs
34. Molecular Modeling and Virtual Screening of DNA Methyltransferase Inhibitors
35. Towards the Chemoinformatic-Based Identification of DNA Methyltransferase Inhibitors: 2D- and 3D-Similarity Profile of Screening Libraries
36. Corrigendum to “Antiviral activity of novel 2′-fluoro-6′-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants” [Bioorg. Med. Chem. Lett. 21 (2011) 6328–6331]
37. Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors
38. Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies
39. Chemoinformatic Approaches for Inhibitors of DNA Methyltransferases: Comprehensive Characterization of Screening Libraries
40. ChemInform Abstract: Concise Syntheses of (+)‐Macrosphelides A and B: Studies on the Macro‐Ring Closure Strategy.
41. Computer-Aided Identification of Ligands for GPCR Anti-Obesity Targets
42. 3D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors
43. Concise Syntheses of (+)-Macrosphelides A and B: Studies on the Macro-Ring Closure Strategy
44. A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy
45. Biarylpyrazolyl Oxadiazole as Potent, Selective, Orally Bioavailable Cannabinoid-1 Receptor Antagonists for the Treatment of Obesity
46. Crystal structure of UDP‐N‐acetylglucosamine enolpyruvyl transferase fromHaemophilus influenzaein complex with UDP‐N‐acetylglucosamine and fosfomycin
47. Synthesis and Biological Evaluation of 4(5)-(6-Alkylpyridin-2-yl)imidazoles as Transforming Growth Factor-β Type 1 Receptor Kinase Inhibitors
48. Synthesis and Biological Evaluation of 3-(4-Substituted-phenyl)-N-hydroxy-2-propenamides, a New Class of Histone Deacetylase Inhibitors
49. Rational Design of an Indolebutanoic Acid Derivative as a Novel Aldose Reductase Inhibitor Based on Docking and 3D QSAR Studies of Phenethylamine Derivatives
50. Synthesis and Anti-Renal FibrosisActivity of ConformationallyLocked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosidesas A3Adenosine Receptor Antagonists and Partial Agonists.
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