3,347 results on '"You, L."'
Search Results
2. Comparison of Mixed Reality-Assisted Spinal Puncture with Landmark-Guided Spinal Puncture by Novice Practitioners: A Pilot Study
- Author
-
Gao L, Xu Y, Zhang X, Jiang Z, Wu J, Dong Y, Li M, Jin L, Qiu J, You L, Qin C, and Gu W
- Subjects
augmented reality ,computer simulation ,mixed reality ,spinal puncture ,Medicine (General) ,R5-920 - Abstract
Lei Gao,1,2,* Yidi Xu,1,2,* Xixue Zhang,1,2 Zhaoshun Jiang,1,2 Jiajun Wu,1,2 Yanjun Dong,1,2 Ming Li,3 Liang Jin,3 Jianjian Qiu,4 Lijue You,5 Chunhui Qin,6 Weidong Gu1,2 1Department of Anaesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, People’s Republic of China; 3Department of Radiology, Huadong Hospital affiliated to Fudan University, Shanghai, People’s Republic of China; 4Department of Radiation Oncology, Huadong Hospital affiliated to Fudan University, Shanghai, People’s Republic of China; 5Department of Computer Center, Huadong Hospital affiliated to Fudan University, Shanghai, People’s Republic of China; 6Department of Pain Management, Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weidong Gu, Email hdmz0800@163.comBackground: Performing spinal anaesthesia in elderly patients with ligament calcification or hyperostosis is challenging for novice practitioners. This pilot study aimed to compare the effectiveness of mixed reality-assisted spinal puncture (MRasp) with that of landmark-guided spinal puncture (LGsp) by novice practitioners in elderly patients.Methods: In this pilot study, 36 patients (aged ≥ 65 years) scheduled for elective surgery under spinal anaesthesia by anaesthesiology residents were included. Patients were randomly assigned to the MRasp group (n = 18) or the LGsp group (n = 18). The outcomes included the number of needle insertion attempts, redirection attempts, passes, the rate of successful first-attempt needle insertion, the rate of successful first needle pass, the spinal puncture time, the total procedure time, and the incidence of perioperative complications.Results: The median number of needle insertion attempts was significantly fewer in the MRasp group than in the LGsp group (1.0 vs 2.0, P = 0.023). The proportion of patients with successful first-attempt needle insertion was 72.2% in the MRasp group and 44.4% in the LGsp group (P = 0.176). The incidence of perioperative complications did not significantly differ between the two groups.Conclusion: This pilot study found that novice practitioners made significantly fewer needle insertion attempts in the MRasp group compared to the LGsp group when performing spinal anaesthesia on elderly patients. A future randomized controlled trial (RCT) is warranted to validate its effectiveness.Trial Registration: This trial was registered at https://www.chictr.org.cn/showproj.html?proj=178960 (ChiCTR-IPR-2300068520). Public title: Mixed reality-assisted versus landmark-guided spinal puncture in elderly patients: a randomized controlled pilot study. Principal investigator: Lei Gao. The registration date was February 22, 2023. The date of the first participant enrolment was February 27, 2023.Plain Language Summary: We developed virtual spine-presenting technology and patented optimal trajectory design technology to assist in spinal puncture and reported that the median number of needle insertion attempts was significantly fewer in the mixed reality-assisted spinal puncture group than in the landmark-guided spinal puncture group.Keywords: augmented reality, computer simulation, mixed reality, spinal puncture
- Published
- 2024
3. Human Equilibrative Nucleoside Transporter 1: Novel Biomarker and Prognostic Indicator for Patients with Gemcitabine-Treated Pancreatic Cancer
- Author
-
Xiao J, Zhao F, Luo W, Yang G, Wang Y, Qiu J, Liu Y, You L, Zheng L, and Zhang T
- Subjects
pancreatic cancer ,human equilibrative nucleoside transporter 1 (hent1) ,gemcitabine chemoresistance ,prognostic indicator ,survival improvement ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Jianchun Xiao,1,* Fangyu Zhao,1,* Wenhao Luo,1,* Gang Yang,1 Yicheng Wang,1 Jiangdong Qiu,1 Yueze Liu,1 Lei You,1 Lianfang Zheng,2 Taiping Zhang1,3 1Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China; 2Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China; 3Clinical Immunology Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China*These authors contributed equally to this workCorrespondence: Taiping Zhang, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China, Email zhangtaiping@pumch.cnAim: This article aimed to find appropriate pancreatic cancer (PC) patients to treat with Gemcitabine with better survival outcomes by detecting hENT1 levels.Methods: We collected surgical pathological tissues from PC patients who received radical surgery in our hospital from September 2004 to December 2014. A total of 375 PC tissues and paired adjacent nontumor tissues were employed for the construction of 4 tissue microarrays (TMAs). The quality of the 4 TMAs was examined by HE staining. We performed immunohistochemistry analysis to evaluate hENT1 expression in the TMAs. Moreover, we detected hENT1 expression level and proved the role of hENT1 in cell proliferation, drug resistance, migration and invasion in vivo and vitro.Results: The results indicated that low hENT1 expression indicated a significantly poor outcome in PC patients, including shortened DFS (21.6± 2.8 months versus 36.9± 4.0 months, p< 0.001) and OS (33.6± 3.9 versus 39.6± 3.9, p=0.004). Meanwhile, patients in stage I/II of TNM stage had a longer OS (40.2± 3.4 versus 15.4± 1.7, p=0.002) and DFS (31.0± 3.1 versus 12.4± 1.9, p=0.016) than patients in stage III/IV. Patients in M0 stage had a longer OS (39.7± 3.4 versus 16.2± 1.9, p=0.026) and DFS(30.7± 3.0 versus 11.8± 2.2, p=0.031) than patients in M1 stage, and patients with tumors not invading the capsule had a better DFS than those with tumor invasion into the capsule (30.8± 3.0 versus 12.6± 2.3, p=0.053). Patients with preoperative CA19-9 values ≤ 467 U/mL have longer DFS than that of patients who had preoperative CA19-9 values > 467 U/mL (37.9± 4.1 versus 22.9± 4.0, p=0.04). In the subgroup analysis, a high hENT1 expression level was related to a longer OS(39.4± 4.0 versus 31.5± 3.9, p=0.001) and DFS(35.7± 4.0 versus 20.6± 2.7; p< 0.0001) in the Gemcitabine subgroup.Conclusion: PC patients with high hENT1 expression have a better survival outcomes when receiving Gemcitabine. hENT1 expression can be a great prognostic indicator for PC patients to receive Gemcitabine treatment.Keywords: pancreatic cancer, human equilibrative nucleoside transporter 1, hENT1, gemcitabine chemoresistance, prognostic indicator, survival improvement
- Published
- 2024
4. Pharmacokinetics, Bioavailability, and Tissue Distribution of the Kirsten Rat Sarcoma Inhibitor Adagrasib in Rats Using UPLC-MS/MS
- Author
-
Lei P, Shen W, Tang H, You L, Chen G, Tang Y, and Lu W
- Subjects
adagrasib ,uplc-ms/ms ,pharmacokinetics ,tissue distribution ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Pan Lei,1,2 Wanying Shen,2 Huijuan Tang,2 Li You,2 Guoyi Chen,2 Yijun Tang,1 Wei Lu3 1Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China; 2Hubei Hongshan Laboratory, College of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People’s Republic of China; 3Department of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, People’s Republic of ChinaCorrespondence: Yijun Tang, Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China, Email tyj_799@taihehospital.com Wei Lu, Department of Pharmacy, Taihe Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China, Email luwei0903@taihehospital.comPurpose: Adagrasib is a selective and reversible inhibitor of KRAS G12C, which significantly delays the progression of solid tumors. However, the absorption, distribution, metabolism, and excretion of adagrasib in vivo are unclear. This study explores the absorption and distribution of adagrasib in vivo.Methods: An ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry (UPLC-MS/MS) method was established for the determination of adagrasib in the rat plasma and tissue. Sprague-Dawley rats were intravenous administrated (5 mg/kg) and oral administrated (30 mg/kg) with adagrasib, and the plasma concentration of adagrasib was determined. After single oral administration of adagrasib (30 mg/kg), the heart, liver, spleen, lung, kidney, intestine, and pancreas were excised. The organs were homogenized with saline solution, and the concentration of adagrasib in tissues was determined.Results: The intra- and inter-day accuracy were from 84.90% to 113.47%, and the precision was within ± 15%. The matrix effect and recovery were within ± 15%. The maximum plasma concentration (Cmax) of adagrasib was 677.45 ± 58.72 ng/mL. The elimination half-life time (t1/2) was 3.50 ± 0.21 h after oral administration and 2.08 ± 0.54 h after intravenous administration. The oral bioavailability was 50.72%. The highest concentrations of adagrasib in liver was 5047.80 ± 676.48 ng/g at 2 h after administration, and it was still detectable at 24 hours after administration.Conclusion: Adagrasib was slowly absorbed and cleared rapidly, and it was also widely distributed in vivo. This study provides a potential reference for adagrasib in clinical studies.Keywords: adagrasib, UPLC-MS/MS, pharmacokinetics, tissue distribution
- Published
- 2024
5. The Effect of Group Identity on Chinese College Students’ Social Mindfulness: Testing a Moderated Mediation Model
- Author
-
Guo X and You L
- Subjects
group identity ,social mindfulness ,empathy ,awe ,Psychology ,BF1-990 ,Industrial psychology ,HF5548.7-5548.85 - Abstract
Xinyi Guo, Lin You Center for Collaborative Innovation of Civilization Practice in New Era, Jiangxi Normal University, Nanchang, Jiangxi, People’s Republic of ChinaCorrespondence: Lin You, Center for Collaborative innovation of Civilization Practice in New Era, Jiangxi Normal University, Nanchang, Jiangxi, 330022, People’s Republic of China, Tel +86 791-88122985, Email 18137809001@163.comPurpose: The current study examined the effect of group identity on social mindfulness, how awe mediates this effect, and lastly how empathy may moderate the various indirect pathway.Methods: A total of 2041 Chinese college students were recruited from different universities or colleges to complete the questionnaire including group identity scale, awe scale, empathy scale and social mindfulness scale. This study was conducted using random and convenient sampling, as well as SPSS and its plugin PROCESS as a statistical tool.Results: The present study showed that group identity was positively associated with awe and social mindfulness. Awe was positively associated with social mindfulness. Empathy further moderated the relationship between group identity and awe, awe and social mindfulness, as well as group identity and social mindfulness.Conclusion: The findings of this study shed light on a correlation between group identity and social mindfulness. Furthermore, this study emphasizes the practical importance of intervening in the empathy level of students who have poor empathy in order to increase their social mindfulness.Keywords: group identity, social mindfulness, empathy, awe
- Published
- 2024
6. Central Sensitization in Patients with Chronic Pain Secondary to Carpal Tunnel Syndrome and Determinants
- Author
-
Feng B, Gong C, You L, Lin Y, Wang Y, and Ip WY
- Subjects
central sensitization ,chronic pain ,carpal tunnel syndrome ,determinants ,Medicine (General) ,R5-920 - Abstract
Beibei Feng,1– 4,* Chen Gong,1,3,4,* Longfei You,1,3,4,* Yangyang Lin,1,3,4 Yafei Wang,1,3,4 Wing Yuk Ip,2 Yuling Wang1,3,4 1Department of Rehabilitation Medicine, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Department of Orthopaedics & Traumatology, the University of Hong Kong, Hong Kong, Special Administrative Regions, People’s Republic of China; 3Guangdong Provincial Clinical Research Center for Rehabilitation Medicine, Guangzhou, People’s Republic of China; 4Biomedical Innovation Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuling Wang, Department of Rehabilitation Medicine, the Sixth Affiliated Hospital, Sun Yat-sen University, No. 26, Yuancun 2nd Cross Road, Guangzhou, 510655, People’s Republic of China, Tel + 86-20-38476737, Fax +86-20-38254221, Email wangyul@mail.sysu.edu.cn Wing Yuk Ip, Department of Orthopaedics & Traumatology, the University of Hong Kong, Hong Kong, Special Administrative Regions, People’s Republic of China, Tel +852-22554581, Fax +852-28174392, Email wyip@hku.hkPurpose: Central sensitization (CS) is commonly seen in chronic pain disorders, including neuropathic pain. However, there exist inconsistencies concerning the presence of CS in chronic pain secondary to carpal tunnel syndrome (CTS). CS and neuropathic pain manifestations in CTS remain not well established. Therefore, this study aims to investigate the CS and pain profiles in patients with CTS and to explore the potential determinants associated with CS.Patients and Methods: Patients with suspected CTS symptoms lasting 3 months or above and healthy controls were enrolled. History, physical examinations, and nerve conduction studies were employed to confirm the diagnosis and severity of median nerve dysfunction. The central sensitization inventory (CSI) was used to screen CS. Other outcomes included neuropathic pain, CTS-specific symptom severity and functions, emotion, and health-related quality of life. Between-group comparisons were conducted in terms of the CS presence. Logistic regression analysis was performed to identify determinants associated with CS.Results: Over 60% of participants with CTS were found with clinical CS, significantly higher than that in the control group. More than 70% of the CTS participants were identified to have possible or very likely neuropathic pain components. In addition, one-fourth of CTS cases had depression or anxiety. Anxiety was associated with an increased risk of developing CS in CTS (adjusted OR=1.31, 95% CI 1.08– 1.59), whereas higher self-perceived general health rating was negatively associated with the presence of CS (adjusted OR=0.92, 95% CI 0.88– 0.97) in the multivariate adjusted regression model.Conclusion: CS is prevalent in patients with CTS. Predominant neuropathic pain characteristics were uncovered in CTS patients as well as comorbid psychological distress. Significant association was found between anxiety and CS presence. Self-perceived general health was inversely related to CS. Further research is warranted to explore the mechanisms of anxiety and central pain processing in painful entrapment neuropathy.Keywords: central sensitization, chronic pain, carpal tunnel syndrome, determinants
- Published
- 2023
7. An Analytical Study into Effects of Anisotropic Fibers on Thermomechanical Stresses in Unidirectional Composites
- Author
-
You, L. H.
- Subjects
Materials of engineering and construction. Mechanics of materials ,TA401-492 - Published
- 2002
- Full Text
- View/download PDF
8. Quantum interference between independent solid-state single-photon sources separated by 300 km fiber
- Author
-
You, Xiang, Zheng, Ming-Yang, Chen, Si, Liu, Run-Ze, Qin, Jian, Xu, M. -C., Ge, Z. -X., Chung, T. -H., Qiao, Y. -K., Jiang, Y. -F., Zhong, H. -S., Chen, M. -C., Wang, H., He, Y. -M., Xie, X. -P., Li, H., You, L. -X., Schneider, C., Yin, J., Chen, T. -Y., Benyoucef, M., Huo, Yong-Heng, Hoefling, S., Zhang, Qiang, Lu, Chao-Yang, and Pan, Jian-Wei
- Subjects
Quantum Physics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
In the quest to realize a scalable quantum network, semiconductor quantum dots (QDs) offer distinct advantages including high single-photon efficiency and indistinguishability, high repetition rate (tens of GHz with Purcell enhancement), interconnectivity with spin qubits, and a scalable on-chip platform. However, in the past two decades, the visibility of quantum interference between independent QDs rarely went beyond the classical limit of 50$\%$ and the distances were limited from a few meters to kilometers. Here, we report quantum interference between two single photons from independent QDs separated by 302 km optical fiber. The single photons are generated from resonantly driven single QDs deterministically coupled to microcavities. Quantum frequency conversions are used to eliminate the QD inhomogeneity and shift the emission wavelength to the telecommunication band. The observed interference visibility is 0.67$\pm$0.02 (0.93$\pm$0.04) without (with) temporal filtering. Feasible improvements can further extend the distance to 600 km. Our work represents a key step to long-distance solid-state quantum networks., Comment: 14 pages, 5 figures
- Published
- 2021
9. The impacts of exposure to risk factors during youth on the increasing global trend of early-onset pancreatic cancer
- Author
-
Cai, J., Lu, B., Chen, H., Lu, M., Zhang, Y., Luo, C., You, L., Dai, M., and Zhao, Y.
- Published
- 2024
- Full Text
- View/download PDF
10. Effect of temperature on corrosion fatigue behavior of Inconel Alloy 690TT steam generator tube
- Author
-
Li, Z.H., Lu, Y.H., You, L., Zhang, X.F., Wang, L., Tian, D.H., Zhang, W.D., and Shoji, T.
- Published
- 2024
- Full Text
- View/download PDF
11. Single-photon distributed free-space spectroscopy
- Author
-
Yu, S., Zhang, Z., Xia, H., Dou, X., Li, M., Wei, T., Wang, L., Jiang, P., Wu, Y., Zhang, C., You, L., Hu, Y., Wu, T., Zhao, L., Shangguan, M., Tao, L., and Qiu, J.
- Subjects
Physics - Atmospheric and Oceanic Physics ,Physics - Optics - Abstract
Spectroscopy is a well-established nonintrusive tool that has played an important role in identifying substances and quantifying their compositions, from quantum descriptions to chemical and biomedical diagnostics. Challenges exist in accurate measurements in dynamic environments, especially for understanding chemical reactions in arbitrary free-space. We develop a distributed free-space spectroscopy realized by a comb-referenced frequency-scanning single-photon lidar, providing multidimensional (time-range-spectrum) remote sensing. A continuous field experiment over 72 hours is deployed to obtain the spectra of multiple molecules (CO2 and HDO) in free-space over 6 km, with a range resolution of 60 m and a time resolution of 10 min over a spectrum span of 30 GHz. The CO2 and HDO concentrations are retrieved from the spectra acquired. This distributed free-space spectroscopy holds much promise for increasing knowledge of atmospheric environments and chemistry research, especially for complex molecular spectra evolution in any location over large areas., Comment: 5 pages, 5 figures
- Published
- 2020
12. Electroacupuncture Pretreatment at Zusanli (ST36) Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice by Reducing Oxidative Stress via Activating Vagus Nerve-Dependent Nrf2 Pathway
- Author
-
Jiang H, Shang Z, You L, Zhang J, Jiao J, Qian Y, Lin J, Wang F, Gao Y, Kong X, and Sun X
- Subjects
inflammation ,liver ,proteomics ,Pathology ,RB1-214 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Haochen Jiang,1,2,* Zhi Shang,2,* Liping You,1,2,* Jinghao Zhang,1 Junzhe Jiao,2 Yihan Qian,2 Jiacheng Lin,2 Fang Wang,2 Yueqiu Gao,1 Xiaoni Kong,2 Xuehua Sun1 1Department of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Central Laboratory, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuehua Sun, Department of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China, Email susan_sxh@shutcm.edu.cn Xiaoni Kong, Central Laboratory, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China, Email xiaonikong@shutcm.edu.cnBackground and Purpose: Current pharmacological approaches to prevent hepatic ischemia/reperfusion injury (IRI) are limited. To mitigate hepatic injury, more research is needed to improve the understanding of hepatic IRI. Depending on traditional Chinese medicine (TCM) theory, acupuncture therapy has been used for the treatment of ischemic diseases with good efficacy. However, the efficacy and mechanism of acupuncture for hepatic IRI are still unclear.Methods: Blood provided to the left and middle lobe of mice livers was blocked with a non-invasive clamp and then the clamps were removed for reperfusion to establish a liver IRI model. Quantitative proteomics approach was used to evaluate the impact of EA pretreatment on liver tissue proteome in the IRI group. Serum biochemistry was used to detect liver injury, inflammation, and oxidative stress levels. H&E staining and TUNEL staining were used to detect hepatocyte injury and apoptosis. Immunohistochemistry and ELISA were used to detect the degree of inflammatory cell infiltration and the level of inflammation. The anti-inflammatory and antioxidant capacities were detected by Quantitative RT-PCR and Western blotting.Results: We found that EA at Zusanli (ST36) has a protective effect on hepatic IRI in mice by alleviating oxidative stress, hepatocyte death, and inflammation response. Nuclear factor E2-related factor 2 (Nrf2) as a crucial target was regulated by EA and was then successfully validated. The Nrf2 inhibitor ML385 and cervical vagotomy eliminated the protective effect in the EA treatment group.Conclusion: This study firstly demonstrated that EA pretreatment at ST36 significantly ameliorates hepatic IRI in mice by inhibiting oxidative stress via activating the Nrf2 signal pathway, which was vagus nerve-dependent.Keywords: inflammation, liver, proteomics
- Published
- 2023
13. Single-photon linear polarimeter based on a superconducting nanowire array
- Author
-
Sun, X. Q., Zhang, W. J., Zhang, C. J., You, L. X., Xu, G. Z., Huang, J., Li, H., Wang, Z., and Xie, X. M.
- Subjects
Physics - Applied Physics - Abstract
Superconducting nanowire single-photon detectors (SNSPDs) have attracted remarkable interest for visible and near infrared single-photon detection, owing to their outstanding performance. Conventional SNSPDs are generally used as binary photon-counting detector. Another important characteristic of light, i.e., polarization, has not been resolved using standalone SNSPDs. In this work, we simulated, fabricated, and characterized a linear polarimeter based on a four-pixel NbN superconducting nanowire array, capable of resolving the polarization state of linearly polarized light at the single-photon level. The detector array design is based on a division of focal plane sensor, in which the orientation of each nanowire division (pixel) is offset by 45 degree. Each single nanowire pixel operates as a combination of photon detector and almost linear polarization filter, with an average polarization extinction ratio of approximately 10. The total system detection efficiency with four pixels is approximately 1% at a total dark count rate of 680 cps, when the detector array is free-space coupled and illuminated with 1550 nm photons. The Stokes parameters are extracted from polarization measurements of the four pixels. The mean errors of the measured AoP and DoLP were about -3 degree and 0.12, respectively. Our results indicate that it is possible to develop a scalable polarization polarimeter or imager based on a superconducting nanowire array. This detector array may find promising application in single-photon polarization detection and imaging., Comment: 31 pages,10 figures
- Published
- 2020
14. Boson sampling with 20 input photons in 60-mode interferometers at $10^{14}$ state spaces
- Author
-
Wang, Hui, Qin, Jian, Ding, Xing, Chen, Ming-Cheng, Chen, Si, You, Xiang, He, Yu-Ming, Jiang, Xiao, Wang, Z., You, L., Renema, J. J., Hoefling, Sven, Lu, Chao-Yang, and Pan, Jian-Wei
- Subjects
Quantum Physics ,Condensed Matter - Mesoscale and Nanoscale Physics ,Physics - Optics - Abstract
Quantum computing experiments are moving into a new realm of increasing size and complexity, with the short-term goal of demonstrating an advantage over classical computers. Boson sampling is a promising platform for such a goal, however, the number of involved single photons was up to five so far, limiting these small-scale implementations to a proof-of-principle stage. Here, we develop solid-state sources of highly efficient, pure and indistinguishable single photons, and 3D integration of ultra-low-loss optical circuits. We perform an experiment with 20 single photons fed into a 60-mode interferometer, and, in its output, sample over Hilbert spaces with a size of $10^{14}$ $-$over ten orders of magnitude larger than all previous experiments. The results are validated against distinguishable samplers and uniform samplers with a confidence level of 99.9%., Comment: 23 pages, 14 figures
- Published
- 2019
- Full Text
- View/download PDF
15. The interfacial spin modulation of graphene on Fe(111)
- Author
-
Hong, J., Hwang, H. -N., NDiaye, A. T., Liang, J., Chen, G., Park, Y., Singh, L. T., Jung, Y. G., Yang, J. -H., Jeong, J. -I., Schmid, A. K., Arenholz, E., Yang, H., Bokor, J., Hwang, C. -C., and You, L.
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
When Fe, which is a typical ferromagnet using d- or f-orbital states, is combined with 2D materials such as graphene, it offers many opportunities for spintronics. The origin of 2D magnetism is from magnetic insulating behaviors, which could result in magnetic excitations and also proximity effects. However, the phenomena were only observed at extremely low temperatures. Fe and graphene interfaces could control spin structures in which they show a unique atomic spin modulation and magnetic coupling through the interface. Another reason for covering graphene on Fe is to prevent oxidation under ambient conditions. We investigated the engineering of spin configurations by growing monolayer graphene on an Fe(111) single crystal surface and observed the presence of sharply branched, 3D tree-like domain structures. Magnetization by a sweeping magnetic field (m-H) revealed that the interface showed canted magnetization in the in-plane (IP) orientation. Moreover, graphene could completely prevent the oxidation of the Fe surface. The results indicate possible control of the spin structures at the atomic scale and the interface phenomena in the 2D structure. The study introduces a new approach for room temperature 2D magnetism., Comment: 22 pages, 4 figures
- Published
- 2018
16. 12-photon entanglement and scalable scattershot boson sampling with optimal entangled-photon pairs from parametric down-conversion
- Author
-
Zhong, Han-Sen, Li, Yuan, Li, Wei, Peng, Li-Chao, Su, Zu-En, Hu, Yi, He, Yu-Ming, Ding, Xing, Zhang, W. -J., Li, Hao, Zhang, L., Wang, Z., You, L. -X., Wang, Xi-Lin, Jiang, Xiao, Li, Li, Chen, Yu-Ao, Liu, Nai-Le, Lu, Chao-Yang, and Pan, Jian-Wei
- Subjects
Quantum Physics ,Physics - Optics - Abstract
Entangled photon sources with simultaneously near-unity heralding efficiency and indistinguishability are the fundamental elements for scalable photonic quantum technologies. We design and realize a degenerate entangled-photon source from an ultrafast pulsed laser pumped spontaneous parametric down-conversion (SPDC), which show simultaneously ~97% heralding efficiency and ~96% indistinguishability between independent single photons. Such a high-efficiency and frequency-uncorrelated SPDC source allows generation of the first 12-photon genuine entanglement with a state fidelity of 0.572(24). We further demonstrate a blueprint of scalable scattershot boson sampling using 12 SPDC sources and a 12*12-modes interferometer for three-, four-, and five-boson sampling, which yields count rates more than four orders of magnitudes higher than all previous SPDC experiments. Our work immediately enables high-efficiency implementations of multiplexing, scattershot boson sampling, and heralded creation of remotely entangled photons, opening up a promising pathway to scalable photonic quantum technologies., Comment: 17 pages, 5 figures. the make-SPDC-great-again paper
- Published
- 2018
- Full Text
- View/download PDF
17. Risk factors for gingival invagination: A retrospective study
- Author
-
Han, M., primary, Li, S. H., additional, Yao, Y., additional, Zhao, Yijiao, additional, You, L. P., additional, Zheng, Q., additional, and Xu, X. M., additional
- Published
- 2024
- Full Text
- View/download PDF
18. Decoy-state quantum key distribution over long-distance optical fiber
- Author
-
Guarda, Giulia, primary, Ribezzo, Domenico, additional, Salvoni, Daniela, additional, Bruscino, Ciro, additional, Ercolano, Pasquale, additional, Ejrnaes, Mikkel, additional, Parlato, Loredana, additional, Zhang, C., additional, Li, H., additional, You, L., additional, Vagniluca, Ilaria, additional, De Lazzari, Claudia, additional, Occhipinti, Tommaso, additional, Pepe, Giovanni P., additional, Zavatta, Alessandro, additional, and Bacco, Davide, additional
- Published
- 2024
- Full Text
- View/download PDF
19. Vitamin D Supplementation Is Associated with a Reduction in Self-Reported Falls among Older Adults with Previous Fall History — Feasibility Study
- Author
-
Anton, Stephen D., Mankowski, R. T., Qiu, P., You, L., Bensadon, B. A., Audino, E. J., Custodero, C., Lee, J. H., Hincapie, J., McLaren, C., Leeuwenburgh, C., and Ganesh, S. P.
- Published
- 2022
- Full Text
- View/download PDF
20. Spin-orbit-coupled Bose-Einstein condensates of rotating polar molecules
- Author
-
Deng, Y., You, L., and Yi, S.
- Subjects
Condensed Matter - Quantum Gases - Abstract
An experimental proposal for realizing spin-orbit (SO) coupling of pseudospin-1 in the ground manifold $^1\Sigma(\upsilon=0)$ of (bosonic) bialkali polar molecules is presented. The three spin components are composed of the ground rotational state and two substates from the first excited rotational level. Using hyperfine resolved Raman processes through two select excited states resonantly coupled by a microwave, an effective coupling between the spin tensor and linear momentum is realized. The properties of Bose-Einstein condensates for such SO-coupled molecules exhibiting dipolar interactions are further explored. In addition to the SO-coupling-induced stripe structures, the singly and doubly quantized vortex phases are found to appear, implicating exciting opportunities for exploring novel quantum physics using SO-coupled rotating polar molecules with dipolar interactions., Comment: 8 pages,5 figures
- Published
- 2018
- Full Text
- View/download PDF
21. Challenging local realism with human choices
- Author
-
The BIG Bell Test Collaboration, Abellán, C., Acín, A., Alarcón, A., Alibart, O., Andersen, C. K., Andreoli, F., Beckert, A., Beduini, F. A., Bendersky, A., Bentivegna, M., Bierhorst, P., Burchardt, D., Cabello, A., Cariñe, J., Carrasco, S., Carvacho, G., Cavalcanti, D., Chaves, R., Cortés-Vega, J., Cuevas, A., Delgado, A., de Riedmatten, H., Eichler, C., Farrera, P., Fuenzalida, J., García-Matos, M., Garthoff, R., Gasparinetti, S., Gerrits, T., Jouneghani, F. Ghafari, Glancy, S., Gómez, E. S., González, P., Guan, J. -Y., Handsteiner, J., Heinsoo, J., Heinze, G., Hirschmann, A., Jiménez, O., Kaiser, F., Knill, E., Knoll, L. T., Krinner, S., Kurpiers, P., Larotonda, M. A., Larsson, J. -Å., Lenhard, A., Li, H., Li, M. -H., Lima, G., Liu, B., Liu, Y., Grande, I. H. López, Lunghi, T., Ma, X., Magaña-Loaiza, O. S., Magnard, P., Magnoni, A., Martí-Prieto, M., Martínez, D., Mataloni, P., Mattar, A., Mazzera, M., Mirin, R. P., Mitchell, M. W., Nam, S., Oppliger, M., Pan, J. -W., Patel, R. B., Pryde, G. J., Rauch, D., Redeker, K., Rieländer, D., Ringbauer, M., Roberson, T., Rosenfeld, W., Salathé, Y., Santodonato, L., Sauder, G., Scheidl, T., Schmiegelow, C. T., Sciarrino, F., Seri, A., Shalm, L. K., Shi, S. -C., Slussarenko, S., Stevens, M. J., Tanzilli, S., Toledo, F., Tura, J., Ursin, R., Vergyris, P., Verma, V. B., Walter, T., Wallraff, A., Wang, Z., Weinfurter, H., Weston, M. M., White, A. G., Wu, C., Xavier, G. B., You, L., Yuan, X., Zeilinger, A., Zhang, Q., Zhang, W., and Zhong, J.
- Subjects
Quantum Physics - Abstract
A Bell test is a randomized trial that compares experimental observations against the philosophical worldview of local realism. A Bell test requires spatially distributed entanglement, fast and high-efficiency detection and unpredictable measurement settings. Although technology can satisfy the first two of these requirements, the use of physical devices to choose settings in a Bell test involves making assumptions about the physics that one aims to test. Bell himself noted this weakness in using physical setting choices and argued that human `free will' could be used rigorously to ensure unpredictability in Bell tests. Here we report a set of local-realism tests using human choices, which avoids assumptions about predictability in physics. We recruited about 100,000 human participants to play an online video game that incentivizes fast, sustained input of unpredictable selections and illustrates Bell-test methodology. The participants generated 97,347,490 binary choices, which were directed via a scalable web platform to 12 laboratories on five continents, where 13 experiments tested local realism using photons, single atoms, atomic ensembles, and superconducting devices. Over a 12-hour period on 30 November 2016, participants worldwide provided a sustained data flow of over 1,000 bits per second to the experiments, which used different human-generated data to choose each measurement setting. The observed correlations strongly contradict local realism and other realistic positions in bipartite and tripartite scenarios. Project outcomes include closing the `freedom-of-choice loophole' (the possibility that the setting choices are influenced by `hidden variables' to correlate with the particle properties), the utilization of video-game methods for rapid collection of human generated randomness, and the use of networking techniques for global participation in experimental science., Comment: This version includes minor changes resulting from reviewer and editorial input. Abstract shortened to fit within arXiv limits
- Published
- 2018
- Full Text
- View/download PDF
22. Tailoring precipitation/properties and related mechanisms for a high-strength aluminum alloy plate via low-temperature retrogression and re-aging processes
- Author
-
Hou, L.G., Yu, H., Wang, Y.W., You, L., He, Z.B., Wu, C.M., Eskin, D.G., Katgerman, L., Zhuang, L.Z., and Zhang, J.S.
- Published
- 2022
- Full Text
- View/download PDF
23. Tunable topological phases with fermionic atoms in a one-dimensional flux lattice
- Author
-
Deng, Y., Lü, R., and You, L.
- Subjects
Condensed Matter - Quantum Gases - Abstract
We present a simple scheme for implementing a one-dimensional (1D) magnetic-flux lattice of ultracold fermionic spin-$1/2$ atoms. The resulting tight-binding model supports gapped and gapless topological phases, and chiral currents for Meissner and vortex phases. Its single-particle spectra exhibit topological flat bands at small flux, and the flatness sensitively depends on hopping strength. An effective $p$-wave interaction arises in a $s$-wave paired superfluid. Treating atomic internal states as forming a synthetic dimension and balancing the interplay of magnetic flux and Zeeman field, our model describes a tunable topological Fermi superfluid, which paves the way towards experimental explorations of non-Abelian topological matter in 1D atomic quantum gases., Comment: 6 pages, 4 figures
- Published
- 2017
- Full Text
- View/download PDF
24. Shape transformation and self-alignment of Fe-based nanoparticles
- Author
-
Hong, J, Luo, Q, Jung, D, Je, SG, Kim, Y, Im, MY, Hwang, CC, Khizroev, S, Chung, S, and You, L
- Subjects
Bioengineering ,Nanotechnology ,Generic Health Relevance - Abstract
New types of functional material structures will emerge if the shape and properties are controlled in three-dimensional nanodevices. Possible applications of these would be nanoelectronics and medical systems. Magnetic nanoparticles (MNPs) are especially important in electronics such as magnetic storage, sensors, and spintronics. Also, in those that are used as magnetic resonance imaging contrasts, and tissue specific therapeutic agents, as well as in the labeling and sorting of cells, drug delivery, separation of biochemical products, and in other medical applications. Most of these applications require MNPs to be chemically stable, uniform in size, and controllable in terms of their magnetic properties and shape. In this paper three new functions of iron (Fe)-based nanoparticles are reported: shape transformation, oxidation prevention, and self-alignment. The shape of the Fe nanoparticles could be controlled by changing their oxidation states and properties by using a nanocarbon coating. Full field X-ray microscopy using synchrotron radiation revealed controllable magnetic properties of MNPs at the L3 edge which depended on the oxidation states. Then, inkjet printing was successfully performed to deposit a uniform layer of MNPs by the size.
- Published
- 2019
25. Clinical Efficacy of the Chinese Herbal Medicine Shumian Capsule for Insomnia: A Randomized, Double-Blind, Placebo-Controlled Trial
- Author
-
Chen S, Xu Z, Li Y, Wang T, Yue Y, Hou Z, You L, Lu N, Yin Y, Liu X, Tan L, Ji H, Shi Y, Xin X, Jiang W, and Yuan Y
- Subjects
chinese herbal medicine ,shumian capsule ,insomnia ,polysomnography ,clinical trial ,randomized and double-blind method ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Suzhen Chen,1,2 Zhi Xu,1,2 Yinghui Li,1,2 Tianyu Wang,1,2 Yingying Yue,1,2 Zhenghua Hou,1,2 Linlin You,1,2 Na Lu,1,2 Yingying Yin,1,2 Xiaoyun Liu,1,2 Liangliang Tan,1,2 Houcheng Ji,3 Yaoran Shi,1,2 Xiaoyun Xin,1,2 Wenhao Jiang,1,2 Yonggui Yuan1,2 1Department of Psychosomatics and Psychiatry, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, People’s Republic of China; 2Institute of Psychosomatics, School of Medicine, Southeast University, Nanjing, People’s Republic of China; 3Department of Psychiatry, The Second People’s Hospital of Jiangning District, Nanjing, People’s Republic of ChinaCorrespondence: Yonggui Yuan, Department of Psychosomatics and Psychiatry, ZhongDa Hospital, School of Medicine, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, 210009, People’s Republic of China, Tel +86-25-83285124, Email yygylh2000@sina.comPurpose: Shumian capsule (SMC) is a patent Chinese herbal medicine that can soothe the liver and relieves depression, quiet the spirit. Here, we aimed to investigate the efficacy of SMC for treating insomnia using both scales and polysomnography (PSG).Patients and Methods: A randomized, double-blind, placebo-controlled trial was performed. Twenty-six insomnia patients randomly received SMC (n = 11) or placebo (n = 15) for four weeks. Pittsburgh Sleep Quality Inventory (PSQI), Insomnia Severity Index (ISI), 9-items Patient Health Questionnaire (PHQ-9), 7-items Generalized Anxiety Disorder (GAD-7), 17-item Hamilton Depression Rating Scale (HAMD-17), and Hamilton Anxiety Rating Scale (HAMA) were applied at the baseline and the 2nd, 4th week after treatment. Treatment Emergent Symptom Scale was used to assess adverse reactions. We used PSG to record and analyze sleep features at baseline and after four weeks.Results: PSQI, ISI, PHQ-9, HAMD-17, and HAMA scores decreased significantly after SMC treatment. Also, the total sleep time, rapid-eye-movement (REM) sleep latency, stage 2 sleep, deep sleep, REM sleep, and sleep efficiency improved significantly after SMC treatment. In the placebo group, the only significant change was the decrease of PHQ-9 at week-2. Furthermore, both SMC and placebo reported no adverse events.Conclusion: SMC could safely improve sleep quality with depression and anxiety remission in insomnia patients.Keywords: Chinese herbal medicine, shumian capsule, insomnia, polysomnography, clinical trial, randomized and double-blind method
- Published
- 2022
26. Heat shocks, maize yields, and child height in Tanzania
- Author
-
Block, S., Haile, B., You, L., and Headey, D.
- Published
- 2022
- Full Text
- View/download PDF
27. NbN superconducting nanowire single photon detector with efficiency over 90% at 1550 nm wavelength operational at compact cryocooler temperature
- Author
-
Zhang, W. J., You, L. X., Li, H., Huang, J., Lv, C. L., Zhang, L., Liu, X. Y., Wu, J. J., Wang, Z., and Xie, X. M.
- Subjects
Condensed Matter - Superconductivity ,Physics - Optics ,Quantum Physics - Abstract
The fast development of superconducting nanowire single photon detector (SNSPD) in the past decade has enabled many advances in quantum information technology. The best system detection efficiency (SDE) record at 1550 nm wavelength was 93% obtained from SNSPD made of amorphous WSi which usually operated at sub-kelvin temperatures. We first demonstrate SNSPD made of polycrystalline NbN with SDE of 90.2% for 1550 nm wavelength at 2.1K, accessible with a compact cryocooler. The SDE saturated to 92.1% when the temperature was lowered to 1.8K. The results lighten the practical and high performance SNSPD to quantum information and other high-end applications., Comment: 24 pages, 14 figures, 2 tables
- Published
- 2016
- Full Text
- View/download PDF
28. 3D multilevel spin transfer torque devices
- Author
-
Hong, J, Stone, M, Navarrete, B, Luongo, K, Zheng, Q, Yuan, Z, Xia, K, Xu, N, Bokor, J, You, L, and Khizroev, S
- Subjects
Affordable and Clean Energy ,Physical Sciences ,Engineering ,Technology ,Applied Physics - Abstract
Spin-transfer torque magnetic tunneling junction devices capable of a multilevel three-dimensional (3D) information processing are studied in the sub-20-nm size range. The devices are built using He+ and Ne+ focused ion beam etching. It has been demonstrated that due to their extreme scalability and energy efficiency, these devices can significantly reduce the device footprint compared to the modern CMOS approaches and add advanced features in a 3D stack with a sub-20-nm size using a spin polarized current.
- Published
- 2018
29. Electrically reversible cracks in an intermetallic film controlled by an electric field.
- Author
-
Liu, ZQ, Liu, JH, Biegalski, MD, Hu, J-M, Shang, SL, Ji, Y, Wang, JM, Hsu, SL, Wong, AT, Cordill, MJ, Gludovatz, B, Marker, C, Yan, H, Feng, ZX, You, L, Lin, MW, Ward, TZ, Liu, ZK, Jiang, CB, Chen, LQ, Ritchie, RO, Christen, HM, and Ramesh, R
- Abstract
Cracks in solid-state materials are typically irreversible. Here we report electrically reversible opening and closing of nanoscale cracks in an intermetallic thin film grown on a ferroelectric substrate driven by a small electric field (~0.83 kV/cm). Accordingly, a nonvolatile colossal electroresistance on-off ratio of more than 108 is measured across the cracks in the intermetallic film at room temperature. Cracks are easily formed with low-frequency voltage cycling and remain stable when the device is operated at high frequency, which offers intriguing potential for next-generation high-frequency memory applications. Moreover, endurance testing demonstrates that the opening and closing of such cracks can reach over 107 cycles under 10-μs pulses, without catastrophic failure of the film.
- Published
- 2018
30. A Low-Cost, High-Efficient and Robust-Mechanical Aerogel Made of Melamine Sponge and Carbon Black for Solar Interfacial Water Evaporation
- Author
-
Zheng, Fengang, primary, Shuai, Shunxu, additional, Yuan, Chengrun, additional, Fang, Liang, additional, Weng, Yuyan, additional, and You, L., additional
- Published
- 2024
- Full Text
- View/download PDF
31. High Performance Superconducting Nanowire Single Photon Detectors for QKD Applications
- Author
-
Bruscino, C., primary, Ercolano, P., additional, Salvoni, D., additional, Di Giancamillo, M., additional, Zhang, C., additional, Ejrnaes, M., additional, Li, H., additional, You, L., additional, Parlato, L., additional, Martinelli, M., additional, and Pepe, G. P., additional
- Published
- 2024
- Full Text
- View/download PDF
32. Worldwide cancer statistics of adolescents and young adults in 2019: a systematic analysis of the Global Burden of Disease Study 2019
- Author
-
You, L., Lv, Z., Li, C., Ye, W., Zhou, Y., Jin, J., and Han, Q.
- Published
- 2021
- Full Text
- View/download PDF
33. Succession of phytoplankton functional groups and driving variables in a young canyon reservoir
- Author
-
Liao, N., Li, H., You, L.-H., Chen, M., Zhang, L.-L., An, R.-D., Li, J., and Zhang, Y.-W.
- Published
- 2021
- Full Text
- View/download PDF
34. Harmonic trap resonance enhanced synthetic atomic spin-orbit coupling
- Author
-
Wu, Ling-Na, Luo, Xin-Yu, Xu, Zhi-Fang, Ueda, Masahito, Wang, Ruquan, and You, L.
- Subjects
Condensed Matter - Quantum Gases - Abstract
Spin-orbit coupling (SOC) plays an essential role in many exotic and interesting phenomena in condensed matter physics. In neutral-atom-based quantum simulations, synthetic SOC constitutes a key enabling element. The strength of SOC realized so far is limited by various reasons or constraints. This work reports tunable SOC synthesized with a gradient magnetic field (GMF) for atoms in a harmonic trap. Nearly ten-fold enhancement is observed when the GMF is modulated near the harmonic-trap resonance in comparison with free-space atoms. A theory is developed that well explains the experimental results. Our work offers a clear physical insight into and analytical understanding of how to tune the strength of atomic SOC synthesized with GMF using harmonic trap resonance., Comment: 5 pages, 1 figure
- Published
- 2016
- Full Text
- View/download PDF
35. Exotic Topological States with Raman-Induced Spin-Orbit Coupling
- Author
-
Deng, Y., Shi, T., Hu, H., You, L., and Yi, S.
- Subjects
Condensed Matter - Quantum Gases - Abstract
We propose a simple experimental scheme to realize simultaneously the one-dimensional spin-orbit coupling and the staggered spin-flip in ultracold pseudospin-$1/2$ atomic Fermi gases trapped in square optical lattices. In the absence of interspecies interactions, the system supports gapped Chern insulators and gapless topological semimetal states. By turning on the $s$-wave interactions, a rich variety of gapped and gapless inhomogeneous topological superfluids can emerge. In particular, a gapped topological Fulde-Ferrell superfluid, in which the chiral edge states at opposite boundaries possess the same chirality, is predicted., Comment: 11 pages, 6 figures
- Published
- 2016
- Full Text
- View/download PDF
36. Persistent atomic spin squeezing at the Heisenberg limit
- Author
-
Wu, Ling-Na, Tey, Meng Khoon, and You, L.
- Subjects
Quantum Physics - Abstract
Two well-known mechanisms, one-axis twisting (OAT) and two-axis countertwisting (TACT), generate spinsqueezed states dynamically. The latter provides better spin squeezing (SS) but has not been demonstrated as the form of its interaction does not occur naturally in known physical systems. Several proposals for realizing effective TACT transformed from OAT require stringent experimental conditions in order to overcome the resulting nonstationary (oscillating) SS and continuously varying mean spin directions. This work presents a simple scheme that solves both problems by freezing SS at an optimal point and realizing effectively persistent SS by inhibiting further squeezing dynamics. Explicit procedures are outlined for persistent SS of the TACT limit. Protocols based on our scheme favorably relax experimental demands, which significantly brighten the prospects for realizing TACT.
- Published
- 2016
- Full Text
- View/download PDF
37. Transport through a quantum dot coupled to two Majorana bound states
- Author
-
Zeng, Qi-Bo, Chen, Shu, You, L., and Lv, Rong
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
We investigate electron transport inside a ring system composed of a quantum dot (QD) coupled to two Majorana bound states confined at the ends of a one-dimensional topological superconductor nanowire. By tuning the magnetic flux threading through the ring, the model system we consider can be switched into states with or without zero-energy modes when the nanowire is in its topological phase. We find that the Fano profile in the conductance spectrum due to the interference between bound and continuum states exhibits markedly different features for these two different situations, which consequently can be used to detect the Majorana zero-energy mode. Most interestingly, as a periodic function of magnetic flux, the conductance shows $2\pi$ periodicity when the two Majorana bound states are nonoverlapping (as in an infinitely long nanowire) but displays $4\pi$ periodicity when the overlapping becomes nonzero (as in a finite length nanowire). We map the model system into a QD--Kitaev ring in the Majorana fermion representation and affirm these different characteristics by checking the energy spectrum., Comment: 8 pages, 8 figures
- Published
- 2015
- Full Text
- View/download PDF
38. Superconducting nanowire single-photon detectors at a wavelength of 940 nm
- Author
-
Zhang, W. J., Li, H., You, L. X., He, Y. H., Zhang, L., Liu, X. Y., Yang, X. Y., Wu, J. J., Guo, Q., Chen, S. J., Wang, Z., and Xie, X. M.
- Subjects
Condensed Matter - Superconductivity ,Physics - Optics ,Quantum Physics - Abstract
We develop single-photon detectors comprising single-mode fiber-coupled superconducting nanowires, with high system detection efficiencies at a wavelength of 940 nm. The detector comprises a 6.5-nm-thick, 110-nm-wide NbN nanowire meander fabricated onto a Si substrate with a distributed Bragg reflector for enhancing the optical absorptance. We demonstrate that, via the design of a low filling factor (1/3) and active area ({\Phi} = 10 {\mu}m), the system reaches a detection efficiency of ~60% with a dark count rate of 10 Hz, a recovery time <12 ns, and a timing jitter of ~50 ps., Comment: 12 pages, 3 figures
- Published
- 2015
39. Few-photon imaging at 1550 nm using a low-timing-jitter superconducting nanowire single-photon detector
- Author
-
Zhou, H., He, Y., You, L., Chen, S., Zhang, W., Wu, J., Wang, Z., and Xie, X.
- Subjects
Physics - Optics ,Condensed Matter - Superconductivity ,Physics - Instrumentation and Detectors - Abstract
We demonstrated a laser depth imaging system based on the time-correlated single-photon counting technique, which was incorporated with a low-jitter superconducting nanowire single-photon detector (SNSPD), operated at the wavelength of 1550 nm. A sub-picosecond time-bin width was chosen for photon counting, resulting in a discrete noise of less than one/two counts for each time bin under indoor/outdoor daylight conditions, with a collection time of 50 ms. Because of the low-jitter SNSPD, the target signal histogram was significantly distinguishable, even for a fairly low retro-reflected photon flux. The depth information was determined directly by the highest bin counts, instead of using any data fitting combined with complex algorithms. Millimeter resolution depth imaging of a low-signature object was obtained, and more accurate data than that produced by the traditional Gaussian fitting method was generated. Combined with the intensity of the return photons, three-dimensional reconstruction overlaid with reflectivity data was realized., Comment: 7 pages, 9 figures
- Published
- 2015
- Full Text
- View/download PDF
40. Statistical analysis of the temporal single-photon response of superconducting nanowire single photon detection
- Author
-
He, Y. -H., Chao-Lin, L., Zhang, W. -J., Zhang, L., Wu, J. -J., Chen, S. -J., You, L. -X., and Wang, Z.
- Subjects
Condensed Matter - Superconductivity ,Physics - Instrumentation and Detectors ,Physics - Optics - Abstract
Counting rate is a key parameter of superconducting nanowire single photon detectors (SNSPD) and is determined by the current recovery time of an SNSPD after a detection event. We propose a new method to study the transient detection efficiency (DE) and pulse amplitude during the current recovery process by statistically analyzing the single photon response of an SNSPD under photon illumination with a high repetition rate. The transient DE results match well with the DEs deduced from the static current dependence of DE combined with the waveform of a single-photon detection event. This proves that the static measurement results can be used to analyze the transient current recovery process after a detection event. The results are relevant for understanding the current recovery process of SNSPDs after a detection event and for determining the counting rate of SNSPDs., Comment: 11 pages,4 figures
- Published
- 2015
41. Room-temperature antiferromagnetic memory resistor
- Author
-
Marti, X., Fina, I., Frontera, C., Liu, Jian, Wadley, P., He, Q., Paull, R. J., Clarkson, J. D., Kudrnovský, J., Turek, I., Kuneš, J., Yi, D., Chu, J. -H., Nelson, C. T., You, L., Arenholz, E., Salahuddin, S., Fontcuberta, J., Jungwirth, T., and Ramesh, R.
- Subjects
Condensed Matter - Materials Science - Abstract
The bistability of ordered spin states in ferromagnets (FMs) provides the magnetic memory functionality. Traditionally, the macroscopic moment of ordered spins in FMs is utilized to write information on magnetic media by a weak external magnetic field, and the FM stray field is used for reading. However, the latest generation of magnetic random access memories demonstrates a new efficient approach in which magnetic fields are replaced by electrical means for reading and writing. This concept may eventually leave the sensitivity of FMs to magnetic fields as a mere weakness for retention and the FM stray fields as a mere obstacle for high-density memory integration. In this paper we report a room-temperature bistable antiferromagnetic (AFM) memory which produces negligible stray fields and is inert in strong magnetic fields. We use a resistor made of an FeRh AFM whose transition to a FM order 100 degrees above room-temperature, allows us to magnetically set different collective directions of Fe moments. Upon cooling to room-temperature, the AFM order sets in with the direction the AFM moments pre-determined by the field and moment direction in the high temperature FM state. For electrical reading, we use an antiferromagnetic analogue of the anisotropic magnetoresistance (AMR). We report microscopic theory modeling which confirms that this archetypical spintronic effect discovered more than 150 years ago in FMs, can be equally present in AFMs. Our work demonstrates the feasibility to realize room-temperature spintronic memories with AFMs which greatly expands the magnetic materials base for these devices and offers properties which are unparalleled in FMs.
- Published
- 2015
- Full Text
- View/download PDF
42. Tunable spin-orbit coupling synthesized with a modulating gradient magnetic field
- Author
-
Luo, Xinyu, Wu, Lingna, Chen, Jiyao, Guan, Qing, Gao, Kuiyi, Xu, Zhi-Fang, You, L., and Wang, Ruquan
- Subjects
Condensed Matter - Quantum Gases - Abstract
We report the observation of tunable spin-orbit coupling (SOC) for ultracold $^{87}$Rb atoms in hyperfine spin-1 states. Different from most earlier experiments where atomic SOC of pseudo-spin-1/2 are synthesized with Raman coupling lasers, the scheme we demonstrate employs a gradient magnetic field (GMF) with ground state atoms and is immune to atomic spontaneous emission. The effect of the SOC is confirmed through the studies of: 1) the collective dipole oscillation of an atomic condensate in a harmonic trap after the synthesized SOC is abruptly turned on; and 2) the minimum energy state at a finite adiabatically adjusted momentum when the SOC strength is slowly ramped up. The coherence properties of the spinor condensates remain very good after interacting with modulating GMFs, which prompts the enthusiastic claim that our work provides a new repertoire for synthesized gauge fields aimed at quantum simulation studies with cold atoms., Comment: 8 pages, 5 figures
- Published
- 2015
- Full Text
- View/download PDF
43. Intermediate-level doping strategy to simultaneously optimize power factor and phonon thermal conductivity for improving thermoelectric figure of merit
- Author
-
Ren, W., Song, Q., Zhu, H., Mao, J., You, L., Gamage, G.A., Zhou, J., Zhou, T., Jiang, J., Wang, C., Luo, J., Wu, J., Wang, Z., Chen, G., and Ren, Z.
- Published
- 2020
- Full Text
- View/download PDF
44. INFLUENCE OF ADDITIONAL STRESS CAUSED BY MINING SUBSIDENCE ON BLAST FURNACE IN METALLURGICAL MINING AREA.
- Author
-
FU, W. L. and YOU, L. W.
- Subjects
- *
MINE subsidences , *MINES & mineral resources , *BLAST effect , *DEFORMATION of surfaces , *BLAST furnaces , *UNDERGROUND areas - Abstract
Underground goaf in metallurgical mining area leads to surface subsidence and has destructive effect on blast furnace. This paper studies the influence of underground goaf on blast furnace.The overlying strata and surface subsidence due to the formed gob area after the underground mining led to a different degree of destruction to blast furnace. Hence, blast furnace was modeled to theoretically analyze the additional stress applied to blast furnace body and foundation when withstanding the surface deformation. On this basis, the anti-deformation structure was designed to analyze the influences of Class I - IN surface deformation on the setting of Blast furnace body unit [ABSTRACT FROM AUTHOR]
- Published
- 2024
45. Effect of Fluid Exposure on Mechanical Properties of Organic-Rich Shale and Field Applications
- Author
-
Lin, C., Kang, Y. L., You, L. J., Yan, X. P., Chen, Q., Wu, Wei, Series Editor, Qu, Zhan, editor, and Lin, Jia'en, editor
- Published
- 2019
- Full Text
- View/download PDF
46. Magnetic fingerprint of interfacial coupling between CoFe and nanoscale ferroelectric domain walls
- Author
-
Zhang, Q, Murray, P, You, L, Wan, C, Zhang, X, Li, W, Khan, U, Wang, J, Liu, K, and Han, X
- Subjects
cond-mat.mtrl-sci ,cond-mat.mes-hall ,Applied Physics ,Engineering ,Physical Sciences ,Technology - Abstract
Magnetoelectric coupling in ferromagnetic/multiferroic systems is often manifested in the exchange bias effect, which may have combined contributions from multiple sources, such as domain walls, chemical defects, or strain. In this study we magnetically "fingerprint" the coupling behavior of CoFe grown on epitaxial BiFeO3 (BFO) thin films by magnetometry and the first-order-reversal-curves (FORC). The contribution to exchange bias from 71°, 109° and charged ferroelectric domain walls (DWs) was elucidated by the FORC distribution. CoFe samples grown on BFO with 71° DWs only exhibit an enhancement of the coercivity, but little exchange bias. Samples grown on BFO with 109° DWs and mosaic DWs exhibit a much larger exchange bias, with the main enhancement attributed to 109° and charged DWs. Based on the Malozemoff random field model, a varying-anisotropy model is proposed to account for the exchange bias enhancement. This work sheds light on the relationship between the exchange bias effect of the CoFe/BFO heterointerface and the ferroelectric DWs, and provides a path for multiferroic device analysis and design.
- Published
- 2016
47. Channel Acquisition for Massive MIMO-OFDM With Adjustable Phase Shift Pilots
- Author
-
You, L, Gao, X, Swindlehurst, AL, and Zhong, W
- Subjects
Adjustable phase shift pilots ,channel acquisition ,channel estimation ,channel prediction ,massive MIMO-OFDM ,pilot phase shift scheduling ,cs.IT ,math.IT ,MD Multidisciplinary ,Networking & Telecommunications - Abstract
We propose adjustable phase shift pilots (APSPs) for channel acquisition in wideband massive multiple-input multiple-output (MIMO) systems employing orthogonal frequency division multiplexing (OFDM) to reduce the pilot overhead. Based on a physically motivated channel model, we first establish a relationship between channel space-frequency correlations and the channel power angle-delay spectrum in the massive antenna array regime, which reveals the channel sparsity in massive MIMO-OFDM. With this channel model, we then investigate channel acquisition, including channel estimation and channel prediction, for massive MIMO-OFDM with APSPs. We show that channel acquisition performance in terms of sum mean square error can be minimized if the user terminals' channel power distributions in the angle-delay domain can be made nonoverlapping with proper pilot phase shift scheduling. A simplified pilot phase shift scheduling algorithm is developed based on this optimal channel acquisition condition. The performance of APSPs is investigated for both one symbol and multiple symbol data models. Simulations demonstrate that the proposed APSP approach can provide substantial performance gains in terms of achievable spectral efficiency over the conventional phase shift orthogonal pilot approach in typical mobility scenarios.
- Published
- 2016
48. DIAGNOSING THE UNCOMMON: BULLOUS PEMPHIGOID PRESENTING AS ECZEMATOUS DERMATITIS AND SEVERE PRURITIS
- Author
-
You, L., primary, Kwah, J., additional, Cohen, J., additional, and Wong, K., additional
- Published
- 2023
- Full Text
- View/download PDF
49. B-384 Genetic Variations Predict Severe Immunotherapy-related Adverse Events for PD-1/PD-L1 Inhibitors
- Author
-
Xin, Z, primary, You, L, additional, Na, F, additional, Li, J, additional, Chen, M, additional, Song, J, additional, Bai, L, additional, Chen, J, additional, Zhou, J, additional, and Ying, B, additional
- Published
- 2023
- Full Text
- View/download PDF
50. Generating an effective magnetic lattice for cold atoms
- Author
-
Luo, Xinyu, Wu, Lingna, Chen, Jiyao, Lu, Rong, Wang, Ruquan, and You, L.
- Subjects
Condensed Matter - Quantum Gases - Abstract
We present a general scheme for synthesizing a spatially periodic magnetic field, or a magnetic lattice (ML), for ultracold atoms using pulsed gradient magnetic fields. Both the period and the depth of the artificial ML can be tuned, immune to atomic spontaneous emission often encountered in optical lattices. The effective Hamiltonian for our 2-dimensional ML has not been discussed previously in condensed matter physics. Its band structures show interesting features which can support topologically nontrivial phases. The technical requirements for implementing our protocol are readily available in today's cold atom experiments. Realization of our proposal will significantly expand the repertoire for quantum simulation with ultracold atoms., Comment: 8 pages, 6 figures
- Published
- 2014
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.