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1. Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, random ised controlled trial.

Author

Yung-Jue Bang, Young-Woo Kim, Han-Kwang Yang, Hyun Cheol Chung, Young-Kyu Park, Kyung Hee Lee, Keun-Wook Lee, Yong Ho Kim, Sang-Ik Noh, Joe Yong Cho, Young Joe Mok, Yeul Hong Kim, Jiafu Ji, Ta-Sen Yeh, Button, Peter, Sirzén, Florin, and Sung Hoon Noh

Subjects
*ADJUVANT treatment of cancer, *OXALIPLATIN, *GERMFREE life, *SURVIVAL analysis (Biometry), *GASTRECTOMY, *STOMACH cancer patients
Abstract

The article presents a study which examines the effect of adjuvant chemotherapy with capecitabine plus oxaliplatin in the disease-free survival following D2 gastrectomy. The study randomly subjected stage II-IIIB gastric cancer patients, who undergone curative D2 gastrectomy, to adjuvant chemotherapy with oral capecitabine and intravenous oxaliplatin treatment or surgery only. Result shows that chemotherapy patients have 74% of 3 year disease-free survival, while surgery only patients show 59%.

Published
2012
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