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3. Study and scaling-up of multi-tip pulsed-corona air discharges for degradation of paracetamol.

Author

Iya-Sou, Djakaou, Merbahi, Nofel, Bouajila, Jalloul, and Yousfi, Mohammed

Subjects
CORONA discharge, THERMAL plasmas, PLASMA flow, REACTIVE oxygen species, LIQUID surfaces
Abstract

This study investigates the paracetamol removal efficiency by multi-tip pulsed corona discharges, highlighting the conditions avoiding mutual effects between two consecutive streamer branching discharges generated by each tip. The results show that the production of reactive oxygen and nitrogen species (RONS) in the liquid phase and the efficiency of paracetamol removal are influenced by the distance between two contiguous tips due to the mutual effects for small inter-tip distances between 4 mm and 8 mm in the case of a fixed inter-electrode distance of 5 mm (i.e. distance between the tip summit and the water surface). Beyond an inter-tip distance of 12 mm (over twice the gap distance), the mutual effects of branching discharges were no longer observed since the field lines did not overlap, making the production and absorption of liquid-phase species more efficient. Furthermore, RONS production was almost linear when moving from one to four tip electrodes: [H2O2]1tip: 0.52 mg l–1 versus [H2O2]4tips: 1.99 mg l–1, a ratio of 3.82. Optimum values were reached for an inter-tip distance of 16 mm. In this case, the enhancement factor in this reactor configuration is the surface integration between the plasma and the liquid surface to be treated. Furthermore, the results show a quasi-exponential increase in the percentage of paracetamol degradation as a function of the number of electrodes, from 4% with a mono-tip configuration to over 78% for a treatment with a four tip one. [ABSTRACT FROM AUTHOR]

Published
2025
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5. Effect of Tip Distribution on Plasma Energy Efficiency in Pulsed Multitip-Plane Corona Discharge at Atmospheric Pressure in Dry and Humid Air

Author

Saber, Karim, Abahazem, Alyen, Merbahi, Nofel, Yousfi, Mohammed, and Guedah, Hasna

Abstract

This study uses an electrical discharge model. It examines how intertip distance affects energy delivered to a reactor tip-plane configuration. The results are validated against previous experimental measurements. Increasing the intertip distance from 5 to 20 mm in dry air results in a proportional increase in delivered energy. The study also evaluates discharge energy, which is useful energy. It shows a loss of energy at 5 mm, but useful energy at 20 mm. Analysis of energy efficiency for different distances shows a significant improvement, varying from 45% to 88%. A subsequent study in humid air shows that no energy is lost beyond 15 mm. The study also looks at how the tip number affects the reactor’s energy delivery. It found that energy delivery increased with the number of tips. However, efficiencies decreased due to mutual effects between tips. As a result, plasma energy efficiency decreased by up to 35% despite the increase in the tip number. These results stress the key role of the threshold distance. It is vital for better energy efficiency and full coverage of target surfaces.

Published
2025
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11. List of Contributors

Author

Adachi, Tetsuo, primary, Akimoto, Yoshihiro, additional, Antoni, Vanni, additional, Bogaerts, Annemie, additional, Eto, Ko, additional, Goto, Osamu, additional, Hamaguchi, Satoshi, additional, Hirata, Takamichi, additional, Hori, Masaru, additional, Ichinose, Masao, additional, Iida, Machiko, additional, Ikeda, Jun-ichiro, additional, Ikehara, Sanae, additional, Ikehara, Yuzuru, additional, Ikuse, Kazumasa, additional, Ishikawa, Kenji, additional, Jawaid, Paras, additional, Jinno, Masafumi, additional, Kajiwara, Takehito, additional, Kajiyama, Hiroaki, additional, Kaneko, Hiroki, additional, Kaneko, Toshiro, additional, Kanetaka, Hiroyasu, additional, Kanzaki, Makoto, additional, Kataoka, Yosky, additional, Kato, Masashi, additional, Kawakami, Hayato, additional, Kikkawa, Fumitaka, additional, Kim, Jaeho, additional, Kitazaki, Satoshi, additional, Kiyama, Satoru, additional, Kobayashi, Chihiro, additional, Kodera, Yasuhiro, additional, Koga, Kazunori, additional, Kondo, Takashi, additional, Kong, Michael G., additional, Koshino, Kazuhiro, additional, Kurita, Hirofumi, additional, Laroussi, Mounir, additional, Miyamoto, Kenji, additional, Mizuno, Akira, additional, Mizuno, Masaaki, additional, Mori, Akira, additional, Motomura, Hideki, additional, Nakamura, Kae, additional, Nakamura, Maki, additional, Nakanishi, Hayao, additional, Nakatsu, Yoshimichi, additional, Nishihara, Shoko, additional, Noguchi, Kyo, additional, Ohno, Mizuki, additional, Omata, Yasuhiro, additional, Ono, Ryo, additional, Okazaki, Yasumasa, additional, Oyane, Ayako, additional, Peng, Yang, additional, Rehman, Mati Ur, additional, Reuter, Stephan, additional, Sakakita, Hajime, additional, Sasaki, Shota, additional, Sato, Awoi, additional, Sato, Takehiko, additional, Satoh, Susumu, additional, Seto, Yasuyuki, additional, Setsuhara, Yuichi, additional, Shimizu, Nobuyuki, additional, Shimizu, Tetsuji, additional, Shiratani, Masaharu, additional, Short, Robert D., additional, Sivakumar, Thillaiampalam, additional, Szili, Endre J., additional, Tabuchi, Yoshiaki, additional, Tachikawa, Masanori, additional, Takano, Noriko, additional, Takashima, Kazunori, additional, Takashima, Keisuke, additional, Takeda, Keigo, additional, Takenaka, Kosuke, additional, Tamura, Yasuhisa, additional, Tanaka, Akiyo, additional, Tanaka, Hiromasa, additional, Tasaka, Ryoko, additional, Temma, Takashi, additional, Terasaki, Hiroko, additional, Tero, Ryugo, additional, Toyokuni, Shinya, additional, Uchida, Giichiro, additional, Uchida, Satoshi, additional, Uchiyama, Hidefumi, additional, Ueda, Masashi, additional, Urayama, Takuya, additional, Utsumi, Fumi, additional, Watanabe, Shunji, additional, Yajima, Ichiro, additional, Yamada, Hiromasa, additional, Yamada, Suguru, additional, Yamagami, Daiki, additional, Yamaguchi, Takashi, additional, Yamanishi, Yoko, additional, Yamato, Masanori, additional, Yasuda, Hachiro, additional, Yokoyama, Naoaki, additional, Yousfi, Mohammed, additional, and Zimmermann, Julia, additional

Published
2019
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15. ESSENTIAL OIL FROM AERIAL PARTS OF RHETINOLEPIS LONADIOIDES (COSS.): EXTRACTION, CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY

Author

Missoum Mansour, Gherib Mohammed, Ziane Mohammed, Ben Braïek Olfa, Yousfi Mohammed, and Amrouche Abdel Ilah

Subjects
Plant Science
Abstract

In this study, the chemical composition and antimicrobial activity of the essential oil (EO) from aerial parts of Rhetinolepis lonadioides collected from southwestern Algeria were assessed. The EO was obtained by hydrodistillation and analyzed by GC/MS. In total, thirty-two compounds were identified representing 80.00% of the total of the EO, withβ-Pinene (41.85%) being the major monoterpenes. Phenanthroquinone (10.39%) and Ethanone, 1-[1,1'-biphenyl]-4-yl- (2.66%) were the main oxygenated monoterpenes, and the diterpene hydrocarbons were mainly represented by m-Camphorene (5.43%). Six EO samples of R. lionadioides collected in location exhibited similar chemical composition evidencing a chemical homogeneity. The agar disc diffusion method showed that R. lonadioides EO was effective against Bacillus cereus, Pseudomonas aeruginosa, and Staphylococcus aureus with diameters of inhibition ranging from 17±2.65 to 12.33±1.13 mm, and the minimum inhibitory concentration (MIC) values were between 4 and 10 µL /mL. The lowest MIC values (4.0 µL/mL) were measured for Bacillus cereus.

Published
2022
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16. Laser-induced fluorescence measurements of spatially resolved OH densities in a helium plasma jet interacting with three different targets in the open air

Author

Cosimi, Julien, Marchal, Frederic, Merbahi, Nofel, Eichwald, Olivier, Gardou, Jean-Pierre, Yousfi, Mohammed, Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Institut Pierre-Simon-Laplace (IPSL (FR_636)), École normale supérieure - Paris (ENS-PSL), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-École polytechnique (X)-Centre National d'Études Spatiales [Toulouse] (CNES)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

Subjects
[SPI]Engineering Sciences [physics]
Abstract

International audience; Abstract The presented research work is devoted to the measurements of the absolute densities of ground state OH radicals in an atmospheric pressure helium plasma jet launched in free air onto three different targets. The OH density is measured by using laser induced fluorescence (LIF). The plasma is generated inside a glass tube by a dielectric barrier discharge powered by a mono-polar pulsed high voltage. Estimation of the absolute density is based on a quantitative analysis of the spectral and temporal component of the LIF signal and does not require any assumption on the densities of colliding species. Based on this analysis, the spatially-resolved density distributions of OH radicals are determined in front of three different target (metallic, dielectric, and ultra-pure water) placed in the open air at 2 cm from the exit of the glass tube. In order to also investigate the temporal behaviour of the OH densities, and the influence of the gas flow rate and of the amplitude of the voltage-pulse, planar LIF (pLIF) has been performed investigating the fluorescence signal (i) during the intervals of the discharge pulses, (ii) for various gas flow rates, and (iii) as a function of the amplitude of the voltage pulse. In the free jet configuration without a target, the OH densities were determined to be in the order of 1019 m-3, whereas they increased up to a factor of 10 in contact with a target. The spatial distributions were also influenced by the dielectric properties of the target: in the case of the metallic target, the maximum of the OH density was found to be in the center between the exit of the glass tube and the target, whereas in the case of the dielectric target, the maximum was found to be close to the surface of the target. In the case of ultra-pure water, the densities were equally distributed between the exit of the glass tube and the target. With this work, the influence of a target on the production of OH radicals was demonstrated, which enables the optimisation of the plasma parameters for an efficient production of OH radicals in front of a target with various dielectric properties.

Published
2023
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18. Modeling of the $\mathrm{N}_2^+$ ion in cold helium plasma II: transport properties of $\mathrm{N}_2^+$ in helium

Author

Paláček, Stanilas, Beseda, Martin, Kalus, René, Benhenni, Malika, Gadéa, Florent, Leininger, Thierry, Yousfi, Mohammed, IT4Innovations - National Supercomputing Center [Ostrava], Technical University of Ostrava [Ostrava] (VSB), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Groupe Méthodes et outils de la chimie quantique (LCPQ) (GMO), Laboratoire de Chimie et Physique Quantiques Laboratoire (LCPQ), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Fédération de recherche « Matière et interactions » (FeRMI), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), and Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
Abstract

A detailed modeling of N$_2^+$ transport properties in helium gas has been performed by employing Monte Carlo calculations based on ab initio collision cross-sections reported by our group in a preceding paper (S Paláček et al 2022 Plasma Sources Sci. Technol. 31 105004). A broad range of the reduced electric field ($E/N$) is considered to provide data directly usable in macroscopic modeling of processes in cold helium plasmas. The N$_2^+$ mobility in helium gas at room temperature (T = 300 K), the characteristic energies of its longitudinal and transversal diffusion, and the rate constant of the N$_2^+$ dissociation induced by collisions with helium atoms have been calculated. The effect of the N$_2^+$ initial rotational-vibrational excitation is investigated as well as the effect of the rotational alignment of the N$_2^+$ molecule. A direct comparison with N$_2^+$/He mobility experimental data is performed as well as indirect tests of theoretical estimates of the characteristic diffusion energies by comparing the latter with pseudo-experimental data obtained from mobility experiments via an inverse-method approach

Published
2023
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20. Numerical Analysis of a 3D Unit Cell Model for Soft Soil Reinforced with Different Granular Columns.

Author

Yousfi, Mohammed Amin, Guettala, Salim, Debbabi, Imad Eddine, and Douara, Taha-Hocine

Subjects
*REINFORCED soils, *UNIT cell, *STONE columns, *CONSTRUCTION & demolition debris, *NUMERICAL analysis
Abstract

Recycled aggregates have been increasingly considered in recent years, owing to the limited supply of natural aggregates coupled with the corresponding carbon footprint. Recycled aggregates are aggregates prepared from construction and demolition waste. Their use aims to reduce energy consumption and contributes to reducing waste harmful to the environment. This study is based on a number of numerical tests using the finite element method of PLAXIS 3D software with the elastic-perfectly plastic behavior model and the Mohr flow criterion for all materials. A unit cell model of soft soil treated with three types of granular columns was loaded to failure: ordinary stone columns (OSCs), sand-fiber mix (SFM) and recycled aggregate porous concrete pile (RAPP). An extensive parametric study was conducted to investigate the effect of column type, friction angle, elasticity modulus, column length and geotextile effective stiffness on the behavior of soft soils. The results of numerical tests indicated that the bearing capacity of the recycled aggregate columns is three times greater than that of columns of natural aggregates. The findings of this research are given in the form of load-settlement graphs, which made it possible to release recommendations to carry out works using this technique. [ABSTRACT FROM AUTHOR]

Published
2023
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22. A Numerical Simulation of a Low-Temperature Argon Plasma Jet

Author

YOUSFI, Mohammed, Barkaoui, Ghada, Halima, Ahlem Ben, Jomaa, Neil, Charrada, Kamel, LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Institute of Engineering Studies of Monastir, Institute of Engineering Studies of Monastir, University of Monastir, and Étude des Milieux Ionisés et Réactifs, 5019 Monastir, Tunisia.

Subjects
[PHYS]Physics [physics], Nuclear and High Energy Physics, Argon, Materials science, Atmospheric pressure, Computer simulation, Field (physics), Multiphysics, chemistry.chemical_element, Plasma, Mechanics, Dielectric barrier discharge, Condensed Matter Physics, 7. Clean energy, 01 natural sciences, 010305 fluids & plasmas, [SPI]Engineering Sciences [physics], chemistry, Physics::Plasma Physics, Electric field, 0103 physical sciences, ComputingMilieux_MISCELLANEOUS
Abstract

A plasma jet at atmospheric pressure using a dielectric barrier discharge (DBD) can be very useful in the biomedical field. In this article, a numerical simulation of such plasma jet operating in argon gas and launched in the open air was developed using COMSOL Multiphysics software. Three coupled models are considered in this study. A hydrodynamic investigation is conducted and the dilution of argon in air is considered an initial value in the plasma model. An electrostatic study is developed in order to preview the initial electric field. Finally, a plasma study is carried out and discussed in terms of electron density, electric field distribution, and plasma length. This study is validated by comparing the results to those measured in a similar system in the literature. The results are in good agreement with the literature and correspond to the physics of the plasma jet.

Published
2021
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23. Ab initio approaches for N 2 + and N 2 + / He ions towards modeling of the N 2 + ion in cold helium plasma

Author

Beseda, Martin, Paláček, S., Gadéa, Florent, Leininger, Thierry, Kalus, René, Benhenni, Malika, Yousfi, Mohammed, IT4Innovations - National Supercomputing Center [Ostrava], Technical University of Ostrava [Ostrava] (VSB), Faculty of Electrical Engineering and Computer Science, Groupe Méthodes et outils de la chimie quantique (LCPQ) (GMO), Laboratoire de Chimie et Physique Quantiques Laboratoire (LCPQ), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Fédération de recherche « Matière et interactions » (FeRMI), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), and Université de Toulouse (UT)

Subjects
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
Abstract

International audience

Published
2022
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25. Treatment of Correlated Errors in Structural Equation Models

Author

Hmimou Amal, Hachimi Hanaa, El Kettani Yousfi Mohammed, Hmimou Soumaia, Iaousse M'barek, and El Hadri Zouhair

Subjects
Correlation, Matrix (mathematics), Iterative method, Covariance matrix, Computation, Applied mathematics, Covariance, Structural equation modeling, Mathematics, Data modeling
Abstract

Structural Equation Models allow assessing the conformity of a theoretical model to some given data. The fundamental hypothesis of the covariance-based approach is that the covariance matrix of the model variables can be generated by the model. This matrix is called the implied covariance matrix. Several methods are used for its computation. However, it depends on many assumptions that may sometimes be unrealistic. In this paper, we assess the assumption of the correlation of the error terms and we proposed a correction to the iterative method for the computation of the implied covariance matrix. Theoretical, as well as numerical illustrations, are given to show the advantage of the corrected method.

Published
2021
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27. Atmospheric pressure dielectric barrier discharges under unipolar and bipolar HV excitation in view of chemical reactivity in afterglow conditions

Author

Panousis, Emanuel, Merbahi, Nofel, C1ement, Franck, Ricard, Andre, Yousfi, Mohammed, Papageorghiou, Leberis, Loiseau, Jean-Francis, Eichwald, Olivier, Held, Bernard, and Spyrou, Nicolas

Subjects
Atmospheric pressure -- Research, Plasma (Ionized gases) -- Properties, Plasma (Ionized gases) -- Measurement, Electric discharges -- Research, Electric discharges through gases -- Research, Chemical reaction, Rate of -- Research, Business, Chemistry, Electronics, Electronics and electrical industries
Abstract

This paper deals with atmospheric pressure DBDs driven under unipolar and bipolar pulsed excitation, in a context of chemical reactivity in flowing afterglow conditions. The resulting discharges in air and nitrogen are examined via electrical and optical diagnostics. Then, their yield in the production of active species (ozone for the air afterglow--atomic Nitrogen and [N.sub.2](A) metastables for the [N.sub.2] afterglow) is compared. An effort is made to illustrate the key discharge parameters that are likely to influence the concentrations of neutral active species in afterglow conditions. Index Terms--Atmospheric pressure plasmas, dielectric barrier discharge, electrical discharges, nonthermal reactive plasmas, plasma devices, plasma measurements.

Published
2009

28. Electron swarm coefficients in C[O.sub.2]-[N.sub.2] and C[O.sub.2]-[O.sub.2] mixtures

Author

Yousfi, Mohammed, de Urquijo, Jaime, Juarez, Antonio, Basurto, Eduardo, and Hernandez-Avila, Jose Luis

Subjects
Atmospheric gases -- Properties, Mixtures -- Properties, Carbon dioxide -- Properties, Oxygen -- Properties, Nitrogen -- Properties, Collisions (Physics) -- Research, Diffusion -- Research, Electron transport -- Research, Ionization -- Methods, Plasma (Ionized gases) -- Properties, Plasma (Ionized gases) -- Usage, Business, Chemistry, Electronics, Electronics and electrical industries
Abstract

The electron swarm coefficients (i.e., drift velocity, longitudinal diffusion coefficient, and effective ionization coefficient) have been measured using a time-resolved pulsed Townsend technique in [O.sub.2], [N.sub.2], and C[O.sub.2] and their mixtures C[O.sub.2]-[N.sub.2] and C[O.sub.2]-[O.sub.2], with C[O.sub.2] shares of 20%, 50%, and 80%. Simultaneously, these swarm data have been calculated from an adequate multiterm solution of the Boltzmann equation, using previously validated sets of electron-molecule collision cross sections. We have found good agreement between measurements and calculations, both for the pure gases and mixtures, particularly for the case of the calculated mean electron drift velocity [W.sub.m], which takes into account the effects of longitudinal diffusion and effective ionization. An effort has been placed in covering as high an E/N range as possible (0.01 Td up to 1000 Td) on specific electron swarm data such as transverse and longitudinal characteristic energies, which are also needed for a better understanding of the electrohydrodynamic and kinetic behavior of nonthermal atmospheric pressure electrical discharges. Index Terms--Atmospheric gas mixtures, attachment, basic swarm data, Boltzmann equation solution, collision cross sections, diffusion, electron swarm coefficients, electron transport, ionization, nonthermal plasma applications, time-resolved measurements.

Published
2009

30. Pulsed electric field as a key element to overcome plasma activated liquids limited cytotoxicity in 3D spheroids 8th International

Author

Griseti, Elena, Kolosnjaj-Tabi, Jelena, Gibot, Laure, Rols, Marie-Pierre, Merbahi, Nofel, Yousfi, Mohammed, Golzio, Muriel, Merbahi, Nofel, Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Interactions moléculaires et réactivité chimique et photochimique (IMRCP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Fluides, Energie, Réacteurs, Matériaux et Transferts (FERMAT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), IDeAS - Interfaces Dynamiques et Assemblages Stimulables (IDeAS), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie de Toulouse (ICT), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), and Université de Toulouse (UT)

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], [SPI.PLASMA]Engineering Sciences [physics]/Plasmas, [SPI.PLASMA] Engineering Sciences [physics]/Plasmas
Abstract

International audience

Published
2021

36. Critical analysis on two-dimensional point-to-plane streamer simulations using the finite element and finite volume methods

Author

Ducasse, Olivier, Papageorghiou, Liberis, Eichwald, Olivier, Spyrou, Nicolas, and Yousfi, Mohammed

Subjects
Finite element method -- Usage, Algorithms -- Usage, Plasma physics -- Research, Algorithm, Business, Chemistry, Electronics, Electronics and electrical industries
Abstract

Two different categories of high-order numerical methods are adopted for the electro-hydrodynamic modeling of the streamer: the finite-element method (FEM) with flux-corrected-transport (FCT) technique and the finite-volume method (FVM) with monotonic upwind-centered scheme for conservation-law (MUSCL) algorithm. Specific numerical tests on the transport equation are used to investigate the efficiency of the two methods to propagate sharp density gradients in stationary uniform and nonuniform velocity fields. The streamer simulations are performed in a positive point-to-plane electrodes filled with air at room temperature and atmospheric pressure. The influence of the numerical schemes on the 2-D streamer modeling is analyzed. Both FVM-MUSCL and FEM-FCT accurately describe the streamer propagation and the morphology of the discharge channel, thereby giving similar axial and radial density profiles. Furthermore, the computational cost is higher for the FEM-FCT solver as compared to the FVM-MUSCL one, which is at least twice as fast. However, the unstructured-grid approach adopted by FEM-FCT proves to be very efficient in describing nonuniform geometries. Index Terms--Finite-element method (FEM), finite-volume method (FVM), flux-corrected-transport (FCT) technique, high-order schemes, monotonic upwind-centered scheme for conservation-law (MUSCL) algorithm, Poisson equation, streamer discharge in air, transport equations, 2-D electro-hydrodynamic model.

Published
2007

39. Influence of electron beam spectra on internal electrostatic discharge in Dielectrics

Author

gouriou, tristan, Ribière, Maxime, Eichwald, Olivier, YOUSFI, Mohammed, LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), and SARRETTE, Jean-Philippe

Subjects
[SPI.PLASMA]Engineering Sciences [physics]/Plasmas, [SPI.PLASMA] Engineering Sciences [physics]/Plasmas, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

40. Relaxation of electronic excitations in Kr2+ ions in cold krypton plasma

Author

Van de Steen, Cyril, Benhenni, Malika, Kalus, René, Ćosić, Rajko, Gadéa, Florent, YOUSFI, Mohammed, LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Technical University of Ostrava [Ostrava] (VSB), IT4Innovations - National Supercomputing Center [Ostrava], Modélisation, Agrégats, Dynamique (LCPQ) (MAD), Laboratoire de Chimie et Physique Quantiques (LCPQ), Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées

Subjects
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, [PHYS.PHYS.PHYS-ATOM-PH]Physics [physics]/Physics [physics]/Atomic Physics [physics.atom-ph], [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], [SPI.FLUID]Engineering Sciences [physics]/Reactive fluid environment, [SPI.PLASMA]Engineering Sciences [physics]/Plasmas, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], ComputingMilieux_MISCELLANEOUS
Abstract

International audience; Reaction rate constants have been calculated for electronic transitions in Kr + 2 ions and for their decay as induced by collisions with krypton atoms and/or spontaneous radiation processes. The rate constants have then been used in a series of modelings of electronic relaxation in the ions in cold krypton plasmas with the main focus on relaxation times and final states. It has been shown that the collision-induced (non-radiative) relaxation is much faster than the radiative one and completely dominates with typical relaxation times ranging between nanoseconds and microseconds. The relaxation always ends up in the Kr + 2 electronic ground state, high electronic excitations survive for longer times than lower excitations due to spin-orbit coupling effects.

Published
2019
Full Text
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41. Experimental and numerical investigations of air plasmas induced by multi-MeV pulsed X-ray from low to atmospheric pressures.

Author

Maulois, Mélissa, Ribière, Maxime, Eichwald, Olivier, Yousfi, Mohammed, Pouzalgues, Romain, Garrigues, Alain, Delbos, Christophe, and Aza€ıs, Bruno

Subjects
AERODYNAMICS, PHOTOLUMINESCENCE, PLASMA gases, ATMOSPHERIC pressure, STATIC pressure
Abstract

This research work is devoted to the experimental and theoretical analysis of air plasmas induced by multi-MeV pulsed X-ray for a large pressure range of humid air background gas varying from 20 mbar to atmospheric pressure. The time evolution of the electron density of the air plasma is determined by electromagnetic wave absorption measurements. The measurements have uncertainties of about 630%, taking into account the precision of the dose measurement and also the shot to shot fluctuations of the generator. The experimental electron density is obtained by comparing the measurements of the transmitted microwave signals to the calculated ones. The calculations need the knowledge of the time evolution of the electron mean energy, which is determined by a chemical kinetic model based on a reaction scheme involving 39 species interacting following 265 reactions. During the X-ray pulse, a good agreement is obtained between time evolution of the electron density obtained from absorption measurements and calculations based on the kinetic model. The relative deviation on the maximum electron density and the corresponding plasma frequency is always lower than 10%. The maximum electron density varies from 4×1011 to 3.5×1013 cm-3 between 30 mbar to atmospheric pressure, while the peak of the electron mean energy decreases from 5.64 eV to 4.27 eV in the same pressure range. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
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42. Simulation of 3D Streamer branching using High Performance Computing

Author

Ducasse, Olivier, Plewa, Joseph-Marie, Eichwald, Olivier, Dessante, Philippe, Jacobs, Carolyn, Renon, Nicolas, YOUSFI, Mohammed, Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Laboratoire Génie électrique et électronique de Paris (GeePs), Université Paris-Sud - Paris 11 (UP11)-CentraleSupélec-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Université Pierre et Marie Curie - Paris 6 (UPMC)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Centre Interuniversitaire de Calcul de Toulouse (CICT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Centre d'élaboration de matériaux et d'études structurales (CEMES), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Space Applications Services [Belgium], Calcul en Midi-Pyrénée (CALMIP), and Université de Toulouse (UT)-Université de Toulouse (UT)-PRES Université de Toulouse-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP)

Subjects
[PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], [SPI.PLASMA]Engineering Sciences [physics]/Plasmas, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

44. Plasma Activated Medium (PAM) Effect on Human Colorectal Cancer and Investigation of Cell Death Mechanisms

Author

Chauvin, Julie, Gibot, L., Vicendo, P., Merbahi, Nofel, Rols, M. -P., Yousfi, Mohammed, Golzio, M., Ecole Polytechnique de l'Université d'Orléans, Université d'Orléans (UO), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Interactions moléculaires et réactivité chimique et photochimique (IMRCP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Fluides, Energie, Réacteurs, Matériaux et Transferts (FERMAT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), IDeAS - Interfaces Dynamiques et Assemblages Stimulables (IDeAS), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie de Toulouse (ICT), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Institut de pharmacologie et de biologie structurale (IPBS), and Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SPI.PLASMA]Engineering Sciences [physics]/Plasmas
Abstract

International audience

Published
2018

45. Investigation of the cytotoxicity of Plasma Activated Medium by the quantification of free radical species generated by low-temperature plasma jet in liquid media

Author

Chauvin, Julie, Judée, Florian, Merbahi, Nofel, Vicendo, P., Yousfi, Mohammed, LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Interactions moléculaires et réactivité chimique et photochimique (IMRCP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Fluides, Energie, Réacteurs, Matériaux et Transferts (FERMAT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), IDeAS - Interfaces Dynamiques et Assemblages Stimulables (IDeAS), and Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie de Toulouse (ICT)

Subjects
[SPI.PLASMA]Engineering Sciences [physics]/Plasmas
Abstract

International audience

Published
2018

46. Experimental and numerical characterizations of the current and magnetic fields produced by electrostatic discharge within dielectrics generated by 6 MeV electrons

Author

Gouriou, Tristan, Ribiere, M., Aubert, D., Assaillit, G., Delbos, C., Garrigues, A., Eichwald, Olivier, Yousfi, Mohammed, LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Epidémiosurveillance de protozooses à transmission alimentaire et vectorielle (ESCAPE), Université de Reims Champagne-Ardenne (URCA)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Centre Hospitalier Universitaire de Reims (CHU Reims), Science des Procédés Céramiques et de Traitements de Surface (SPCTS), Université de Limoges (UNILIM)-Ecole Nationale Supérieure de Céramique Industrielle (ENSCI)-Institut des Procédés Appliqués aux Matériaux (IPAM), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Génétique Cellulaire (LGC), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), and Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3)

Subjects
[SPI.PLASMA]Engineering Sciences [physics]/Plasmas
Abstract

International audience

Published
2018

47. Stimulation of germination and growth of Arabidopsis thaliana using low temperature plasmas and plasma activated waters

Author

Bafoil, Maxime, Yousfi, Mohammed, Dunand, C., Merbahi, Nofel, Eichwald, Olivier, Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Laboratoire de Recherche en Sciences Végétales (LRSV), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Biologie du Cancer et de l'Infection (BCI ), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Department Obstetrics and Gynaecology, Grenoble Hospital, Grenoble, France, and Université Grenoble Alpes [2016-2019] (UGA [2016-2019])

Subjects
[SPI.PLASMA]Engineering Sciences [physics]/Plasmas
Abstract

International audience

Published
2018

48. Investigation of effect of Plasma Activated Medium on FaDu (Head & Neck Cancer) MultiCellular Tumor Spheroids

Author

Merbahi, Nofel, Chauvin, Julie, Vicendo, P., Gibot, L., Yousfi, Mohammed, Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Interactions moléculaires et réactivité chimique et photochimique (IMRCP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Fluides, Energie, Réacteurs, Matériaux et Transferts (FERMAT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), IDeAS - Interfaces Dynamiques et Assemblages Stimulables (IDeAS), and Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie de Toulouse (ICT)

Subjects
[SPI.PLASMA]Engineering Sciences [physics]/Plasmas
Abstract

International audience

Published
2018

49. Analysis of reactive oxygen and nitrogen species generated in three liquid media by low temperature helium plasma jet

Author

Chauvin, Julie, Judée, Florian, Vicendo, Patricia, Griseti, Elena, Kolosnjaj-Tabi, Jelena, Gibot, Laure, Fourquaux, Isabelle, Rols, Marie-Pierre, YOUSFI, Mohammed, Merbahi, Nofel, Golzio, Muriel, Ecole Polytechnique de l'Université d'Orléans, Université d'Orléans (UO), Plasmas Réactifs Hors Equilibre (LAPLACE-PRHE), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Interactions moléculaires et réactivité chimique et photochimique (IMRCP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Fluides, Energie, Réacteurs, Matériaux et Transferts (FERMAT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), IDeAS - Interfaces Dynamiques et Assemblages Stimulables (IDeAS), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie de Toulouse (ICT), Mechanics surfaces and materials processing (MSMP), Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Institut de pharmacologie et de biologie structurale (IPBS), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Centre de Microscopie Électronique Appliquée à la Biologie (CMEAB), Toulouse Réseau Imagerie-Genotoul ( TRI-Genotoul), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse]-Toulouse Réseau Imagerie-Genotoul ( TRI-Genotoul), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
0301 basic medicine, Radical, Science, chemistry.chemical_element, Photochemistry, 01 natural sciences, Oxygen, Article, 03 medical and health sciences, chemistry.chemical_compound, [SPI]Engineering Sciences [physics], 0103 physical sciences, [CHIM]Chemical Sciences, Hydrogen peroxide, ComputingMilieux_MISCELLANEOUS, 010302 applied physics, Multidisciplinary, Aqueous solution, Superoxide, Singlet oxygen, Tryptophan, 030104 developmental biology, chemistry, Biochemistry, Medicine, Hydroxyl radical
Abstract

In order to identify aqueous species formed in Plasma activated media (PAM), quantitative investigations of reactive oxygen and nitrogen species (ROS, RNS) were performed and compared to Milli-Q water and culture media without and with Fetal Calf Serum. Electron paramagnetic resonance, fluorometric and colorimetric analysis were used to identify and quantify free radicals generated by helium plasma jet in these liquids. Results clearly show the formation of ROS such as hydroxyl radical, superoxide anion radical and singlet oxygen in order of the micromolar range of concentrations. Nitric oxide, hydrogen peroxide and nitrite-nitrate anions (in range of several hundred micromolars) are the major species observed in PAM. The composition of the medium has a major impact on the pH of the solution during plasma treatment, on the stability of the different RONS that are produced and on their reactivity with biomolecules. To emphasize the interactions of plasma with a complex medium, amino acid degradation by means of mass spectrometry was also investigated using methionine, tyrosine, tryptophan and arginine. All of these components such as long lifetime RONS and oxidized biological compounds may contribute to the cytotoxic effect of PAM. This study provides mechanistic insights into the mechanisms involved in cell death after treatment with PAM.

Published
2017
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