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The rapid advancement of high-tech technologies such as aerospace， electronic information， and biomedicine has required more demands on the properties of advanced ceramic materials. Single-characteristic structural or functional materials cannot meet the current requirements， so the high-performance composite ceramics with integrated structure and function have become global research objectives. Directionally solidified oxide eutectic composite ceramics are a class of structural and functional integrated composite materials developed in recent years for long-term service in ultra-high temperature oxidizing environments. They have characteristics such as high melting point， low density， excellent high-temperature strength， and high-temperature creep performance， while also possessing functional properties such as optics， electromagnetism， and biology. The latest development of directionally solidified structure-function integrated eutectic ceramics was reviewed， specifically focusing on Al2O3-based eutectic ceramic systems. The various preparation methods， technical principles， and growth characteristics associated with directionally solidified eutectic ceramics were summarized. Furthermore， the solidification microstructure and structural characteristics observed in a series of Al2O3-based eutectic ceramics were elaborated. The mechanical， optical， magnetic， and biological properties of composite ceramics and their influencing factors were analyzed， and their characteristics， advantages， and application scope were introduced. Finally， the review summarizes the challenges and key bottlenecks faced by directionally solidified eutectic composite ceramics in engineering applications and proposes the main directions for the development of eutectic composite ceramic materials in terms of forming technology innovation， comprehensive performance improvement， and the development of new systems.

Oxide eutectic ceramics have excellent high specific strength, high temperature resistance, corrosion resistance, oxidation and creep resistance, and so on, which are considered to be the promising materials to be used in ultra-high temperature oxidation, corrosion and other extreme environments. It shows great application prospects in the new generation of high thrust-to-weight ratio aero-engine for high-temperature hot-end structural components. Laser additive manufacturing technology has become one of the most promising cutting-edge technologies for the preparation of high-performance complex structural components in recent years. Crack defect is easy to occur in the process of laser rapid solidification of ceramics, which seriously affects the quality and performance of the oxide eutectic ceramics components. So, it has become a key factor restricting the engineering application. Two typical laser additive manufacturing technologies for ceramics including laser engineered net shaping and laser power bed fusion were briefly summarized. The crack morphology characteristics of different shaped components formed by the above two technologies were analyzed and compared. The formation mechanism of cracks in laser additive manufacturing of oxide ceramics was explored from the perspectives of microstructure characteristics, stress state. Further, a systematic summary was presented focusing on the improvement of microstructures and the reduction of thermal stress to inhibit crack formation through optimization of process parameters, compositional design, and outfield assistance. Finally, it is pointed out that the future development trends and breakthrough directions of oxide eutectic ceramics by laser additive manufacturing in terms of powder properties, forming primary and secondary factors, and forming technology research.

In this study, a new exploration of a classic problem in the field of music aesthetics was carried out through the research methods of cognitive neuroscience and the brain mechanism of the formation of artistic aesthetic value in piano performance based on the theory of multiple intelligences was analyzed. In terms of EEG signal preprocessing, an EEG signal preprocessing method based on baseline average was proposed. In terms of EEG feature extraction, a decision-level feature fusion method is proposed, which uses SVM as the base classifier to extract time-domain, frequency-domain and nonlinear features, respectively, train the base classifier, and integrate the output of multiple basic classifiers through decision fusion. A feature fusion method based on music and ERP was also proposed to predict the response of subjects after listening to a piano performance. Based on DS evidence theory, emotion recognition and classification were carried out using EEG and music features from the perspective of decision-making level fusion. The results showed that piano performance mainly activated the left inferior frontal gyrus, right precentral gyrus, left auxiliary motor area, right superior parietal gyrus, cerebellar Crus1 area, right lingual gyrus and left inferior occipital gyrus, with peak t values of 4.67, 4.8, 5.76, 5.16, 7.02, 7.12 and 8.3, respectively. The activation of auxiliary motor areas, cerebellum, inferior frontal gyrus and other areas indicates that the artistic beauty felt by listening to piano performance can enhance people’s creativity, and the activation of the right superior occipital gyrus can enhance people’s imagination.

Alzheimer’s disease is known as one of the “top ten killers in the world”. Due to lack of effective therapy at present， early pathological changes have captivated widespread attention. Axonal transport dysfunction has been reported as an early pathological feature of many neurodegenerative diseases. However， multiple factors can cause axonal transport dysfunction. In this article， the relationship between axonal transport dysfunction caused by kinesins， microtubules and mitochondria and Alzheimer’s disease was discussed， aiming to provide new ideas for the prevention and treatment of Alzheimer’s disease by in-depth study on axonal transport mechanism of neure.

Roxarsone (V) (Rox(V)) is an organoarsenical compound that poses significant risks to aquatic ecosystems and various diseases. Reducing trivalent 3-amino-4-hydroxyphenylarsonic acid (HAPA(III)) offers a competitive advantage; however, it leads to localized arsenic contamination, which can disrupt the soil microbiome and impede plant growth. Three genes, BsntrA, arsC2, and BsexpA, encoding nitroreductase, arsenate reductase, and MFS transporter, respectively, were identified in the Rox(V)-resistant strain Brevundimonas sp. M20. A three-step approach, including nitroreduction, As(V) reduction, and HAPA(III) secretion, which is responsible for roxarsone(V) resistance, was subsequently confirmed. Moreover, the flavonoid compound baicalin occupied the HAPA(III) delivery space and grabbed the R127 residues via stronger interactions. This steric hindrance prevented the transportation of HAPA(III) by BsexpA to the extracellular space. These results demonstrate a new Rox(V) reduction pathway, providing a potential efflux pump inhibitor to trap more toxins. Highlights: Rox(V) is reduced and secreted via a three-step approach in Brevundimonas sp. M2.0 Rox(V) is progressively reduced to HAPA(V) and HAPA(III) by the nitroreductases BsntrA and the arsenate reductase ArsC2. HAPA(III) is pumped out by the MFS transporter BsexpA. The flavonoid compound baicalin is a BsexpA inhibitor. [ABSTRACT FROM AUTHOR]

Bioimpedance analysis (BIA)–body composition monitoring (BCM) has been used to evaluate the hydration and nutritional status of adults and children on dialysis. However, its clinical application still has challenges, so further exploration is valuable. We used BIA-BCM to evaluate the hydration and nutritional status of children undergoing chronic peritoneal dialysis from 1 July 2021 to 31 December 2022 in the Children's Hospital of Fudan University to explore the clinical value of this method. A total of 84 children on chronic peritoneal dialysis (PD) were included. In the PD group, 16 (19.05%) and 31 (36.90%) had mild and severe overhydration (OH), respectively; 41.27% (26/63) had a low lean tissue index (LTI). In the PD group, patients with relative OH (Re-OH) > 5.6% had significantly higher systolic blood pressure (SBP) and SBP z score (SBPz). Patients with LTI > 12% had significantly higher body mass index (BMI) and BMI z score (BMIz). Canonical correlation analysis indicated a linear relationship (ρ = 0.708) between BIA-BCM hydration and the clinical hydration indicator and a linear relationship (ρ = 0.995) between the BIA-BCM nutritional indicator and the clinical nutritional indicator. A total of 56% of children on chronic peritoneal dialysis had OH, and 41% had a low LTI. In PD patients, SBP and SBPz were correlated with BIA-BCM Re-OH, and BMI and BMIz were correlated with BIA-BCM LTI. BIA-BCM indicators have good clinical value in evaluating hydration and nutrition. [ABSTRACT FROM AUTHOR]

The consensus in the literature is that fiscal decentralisation is a means to reduce corruption. For China, the attenuating effects of fiscal decentralisation are often enhanced by other factors. This paper argues that prior findings serve to facilitate the design of anti‐corruption measures but they do not address why individuals may engage in corruption. This is especially as individual evidence suggests that engaging in corruption is against professional ethos in China. This paper suggests that intergovernmental transfers and the relative level of economic development of where a public servant is serving influence the decision of whether to engage in corruption. Specifically, intergovernmental transfers and a higher level of local economic development directly affect the resources that a local administration has. In turn, this affects the extent to which one may realise their motivations for a career in the public sector. Empirical estimates for 1998–2013 serve to support the hypothesis. Points for practitioners: Fiscal decentralisation mitigates the prevalence of corruption in China in conjunction with other complimentary factors.But engaging in corruption is inconsistent with motivations for a public sector career which include engaging in work for society's greater benefit.Corruption may emerge because public servants feel that they may be unable to achieve their aims for joining the public sector because of local resource constraints.Empirical findings suggest that increased resources to local administrations from intergovernmental transfers and economic development may discourage public servants from deviating from their stated career motivations, that is, engaging in corruption. [ABSTRACT FROM AUTHOR]