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15 results on '"Yue, Baohong"'

7. Additional file 1 of The reference ranges and characteristics of lymphocyte parameters and the correlation between lymphocyte parameters and routine health indicators in adults from China

Author

Liu, Wei, Xu, Jie, Pu, Qiyao, Lan, Mingwei, Zhang, Xiaolu, Gu, Yufeng, Wang, Ying, Zheng, Fan, Qian, Jingjing, Fan, Chunxue, Sui, Jun, Xu, Yanli, Zhang, Yongchen, Luo, Jing, Lin, Xiangyang, Shi, Shaorui, Wang, Liying, Sun, Chengming, Zhou, Maohua, Yue, Baohong, and Wang, Feng

Abstract

Additional file 1: Supplementary Table 1. The demographic, representative laboratory, and lymphocyte parameter results of the participants from 10 centers. Supplementary Figure 1. Correlation between CD3+CD4+ T cell number and age. Each symbol represents an individual donor. Supplementary Figure 2. Correlation between CD3+CD8+ T cell number and other routine indicators including RBC, HB, HDL, PLT, and GLU. Each symbol represents an individual donor. RBC, red blood cell; HB, hemoglobin; HDL, high density lipoprotein; PLT, platelet; GLU, glucose.

Published
2022
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15. [The expression and significance of eotaxin gene in nasal mucosa and CCR3 in bone marrow in model of allergic rhinitis].

Author

Zhou M, Dong M, Wu Y, Wang L, and Yue B

Subjects
Animals, Female, Rats, Rats, Sprague-Dawley, Rhinitis, Allergic, Perennial pathology, Bone Marrow metabolism, Chemokine CCL11 metabolism, Nasal Mucosa metabolism, Receptors, CCR3 metabolism, Rhinitis, Allergic, Perennial metabolism
Abstract

Objective: To study the expression and significance of Eotaxin gene in nasal mucosa and CCR3 in bone marrow in model of allergic rhinitis., Method: Twenty SD rats were randomly divided into allergic rhinitis (AR) group and normal control group. Ovalbumin (OVA) sensitized and challenged rats were used as the model of allergic rhinitis. The leucocytes in the smears of bone marrow and peripheral blood were counted, and the expression of CCR3 in bone marrow was detected by immunohistochemistry. The pathologic samples of nasal mucosa were stained with HE. The expression of Eotaxin mRNA in nasal mucosa was detected by in situ hybridization (ISH), and the expression of Eotaxin in nasal mucosa was detected by immunohistochemistry., Result: The ratio of eosinophils to white cells in bone marrow smears of AR group was significantly higher than that of normal control group (P < 0.01). The ratio of eosinophils to white cells in peripheral bloods mears of AR group was significantly higher than that of normal control group (P < 0.01). Eotaxin positive cell and the expression of Eotaxin mRNA in nasal mucosa of AR group were significantly higher than that of normal control group (P < 0.01). The expression of Eotaxin mRNA significantly positively correlated with the expression of Eotaxin (r = 0.804, P < 0.01). The number of Eotaxin positive cells in nasal mucosa was significantly positively correlated with the number of eosinophils in nasal mucosa of AR group (r = 0.795, P < 0.01). The ratio of CCR3 positive cells to white cells in bone marrow smears of AR group was significantly higher than that of normal control group (P < 0.01). The ratio of CCR3 positive cells to white cells was significantly positively correlated with the ratio of eosinophils to white cells in bone marrow smears of AR group (r = 0.736, P < 0.05)., Conclusion: The expression of Eotaxin and Eotaxin mRNA in nasal mucosa increased, and the expression of CCR3 in bone marrow increased in the model of allergic rhinitis. It supplies a cooperation between CCR3 and Eotaxin to allow rapid mobilization of a pool of bone marrow eosinophils followed by recruitment to the nasal mucosa.

Published
2006

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