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High-temperature calcination was used to modify garnet media. Brunauer–Emmett–Teller (BET) measurements, X-ray diffractometer (XRD), scanning electron microscopy (SEM), zeta potential analysis, and a static adsorption experiment on humic acid removal were carried out to compare unmodified garnet and traditional quartz sand. Fitting adsorption isotherm of the media before and after modification was conducted to determine the adsorption type, and a dynamic filtration experiment was performed to treat micro-polluted water. Results of the characterization analysis and the static adsorption experiment revealed that, compared with the smooth surface of unmodified garnet, the surface of modified garnet media was covered with Fe2O3, which showed a rough concave-convex structure with a specific area that was 2.44 times larger than that of unmodified garnet. The removal efficiency of organic matter after modification increased from 2.5–4.5% to 51.7–63.1%, and the adsorption capacity increased 11–24 times. The adsorption type of the modified garnet media belongs to the Langmuir and Freundlich adsorption mode, while that of the original media belongs to the Freundlich adsorption mode. Results of the dynamic filtration experiment revealed that the effect of modified garnet media on turbidity, CODMn, and UV254 removal was better than that of unmodified garnet and traditional quartz sand.

In this study, the adsorption capacities of peanut shell activated carbon samples prepared using three types of peanut shell as raw material were compared. The effects of activation state, carbonization temperature, carbonization time, adsorption time during decolorization, and dosage on the performance of the peanut shell activated carbon samples were investigated. The performance of the modified peanut shell (activated carbon) on the decolorization of reactive brilliant blue X-BR and the adsorption kinetics were evaluated systematically. Among the three types of peanut shell activated carbon, the activated carbon that was first activated by phosphoric acid and then carbonized at 450°C for 3 h displayed the best performance, with an optimum dosage of 4 g l−1 and an optimum adsorption time of 2 h. The pseudo-second-order kinetics equation and the intraparticle diffusion equation could well describe the adsorption behavior of the activated carbon prepared by phosphoric acid activation. Intraparticle diffusion was not the only factor affecting the adsorption rate of the activated carbon on reactive brilliant blue X-BR. [ABSTRACT FROM AUTHOR]

Reduced adipogenesis is a prominent characteristic of aging adipose tissue and is closely tied to the development of metabolic disorders associated with aging. Epigenetic modification plays a crucial role in the aging process, yet the role of N 6 -methyladenosine (m 6 A), the most prevalent RNA modification, in regulating adipose tissue aging remains uncertain. Our study found that levels of m 6 A and its recognition protein, heterogeneous nuclear ribonucleoprotein C (HNRNPC), decrease in adipose tissue as individuals age. Lower levels of HNRNPC were also linked to reduced adipogenesis during aging. Through loss and gain of function experiments with HNRNPC, we established a positive correlation between HNRNPC and adipogenesis in vitro. Hnrnpc-APKO mice displayed decreased adipogenesis, increased insulin resistance, elevated expression of aging-related and inflammation-related genes, decreased lipogenesis-related genes, and other metabolic disorders compared to their littermates. Additionally, we discovered that HNRNPC facilitated the stability of lymphocyte cytosolic protein 1 (Lcp1) mRNA by binding to the m 6 A motif of LCP1. Overexpression of LCP1 mitigated the inhibition of adipogenesis caused by decreased HNRNPC through modulation of cytoskeletal remodeling. Finally, our findings demonstrate that anti-aging treatments could enhance HNRNPC levels. In conclusion, HNRNPC is positively associated with reduced adipogenesis during aging, and increacing HNRNPC levels through anti-aging treatments highlights its potential as a therapeutic target for addressing metabolic imbalances in adipose tissue related to aging.