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22 results on '"Yun, Dongyuan"'

1. Digital ray: enhancing cataractous fundus images using style transfer generative adversarial networks to improve retinopathy detection

Author

Liu, Lixue, primary, Hong, Jiaming, additional, Wu, Yuxuan, additional, Liu, Shaopeng, additional, Wang, Kai, additional, Li, Mingyuan, additional, Zhao, Lanqin, additional, Liu, Zhenzhen, additional, Li, Longhui, additional, Cui, Tingxin, additional, Tsui, Ching-Kit, additional, Xu, Fabao, additional, Hu, Weiling, additional, Yun, Dongyuan, additional, Chen, Xi, additional, Shang, Yuanjun, additional, Bi, Shaowei, additional, Wei, Xiaoyue, additional, Lai, Yunxi, additional, Lin, Duoru, additional, Fu, Zhe, additional, Deng, Yaru, additional, Cai, Kaimin, additional, Xie, Yi, additional, Cao, Zizheng, additional, Wang, Dongni, additional, Zhang, Xulin, additional, Dongye, Meimei, additional, Lin, Haotian, additional, and Wu, Xiaohang, additional

Published
2024
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2. Shaping school for childhood myopia: the association between floor area ratio of school environment and myopia in China

Author

Zeng, Danqi, Yang, Yahan, Tang, Yang, Zhao, Lanqin, Wang, Xun, Yun, Dongyuan, Chen, Wenben, Shang, Yuanjun, Xu, Andi, Liao, Huipeng, Zhang, Xingying, Lin, Duoru, and Lin, Haotian

Abstract

AimTo investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset.MethodsThis prospective cohort study recruited 136 753 children aged 6–10 years from 108 schools in Shenzhen, China at baseline (2016–2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR was objectively evaluated using geographical information system technology. Mixed-effects logistic regression models were constructed to examine the association of FAR with a 2-year cumulative incidence of myopia among individuals without baseline myopia; multiple linear regression model, with a 2-year cumulative incidence rate of myopia at each school.ResultsOf 101 624 non-myopic children (56.3% boys; mean (SE) age, 7.657±1.182 years) included in the study, 26 391 (26.0%) of them developed myopia after 2 years. In the individual-level analysis adjusting for demographic, socioeconomic and greenness factors, an IQR in FAR was associated with a decreased risk of 2-year myopia incidence (OR 0.898, 95% CI 0.866 to 0.932, p<0.001). Similar findings were observed in the analysis additionally adjusted for genetic and behavioural factors (OR 0.821, 95% CI 0.766 to 0.880, p<0.001). In the school-level, an IQR increase in FAR was found to be associated with a 2.0% reduction in the 2-year incidence rate of myopia (95% CI 1.3% to 2.6%, p<0.001).ConclusionsExposure to higher FAR was associated with a decreased myopia incidence, providing insights into myopia prevention through school built environments in China.

Published
2025
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4. An artificial intelligence and blockchain technology-based data management framework for multicenter randomized controlled trials

Author

Yun, Dongyuan, Wu, Xiaohang, Chen, Xi, Yang, Yahan, Shang, Yuanjun, Liu, Shaopeng, Gunasekeran, Dinesh Visva, Lin, Duoru, Liu, Lixue, Zhao, Lanqin, Chen, Wenben, Chen, Jingjing, Jin, Ling, Wu, Yuxuan, Hong, Jiaming, Hu, Weiling, Lin, Zhenzhe, Cheung, Carol Y., Chen, Xiang, Xie, Peichen, Liu, Zhenzhen, Ding, Changhai, Yu-Wai-Man, Patrick, Yu, Keming, Ting, Daniel Shu Wei, Liu, Yizhi, Zheng, Zibin, Zhao, Gansen, Xia, Zhihua, Wong, Tien Yin, and Lin, Haotian

Published
2025
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7. Deep Learning Performance of Ultra-Widefield Fundus Imaging for Screening Retinal Lesions in Rural Locales

Author

Cui, Tingxin, primary, Lin, Duoru, additional, Yu, Shanshan, additional, Zhao, Xinyu, additional, Lin, Zhenzhe, additional, Zhao, Lanqin, additional, Xu, Fabao, additional, Yun, Dongyuan, additional, Pang, Jianyu, additional, Li, Ruiyang, additional, Xie, Liqiong, additional, Zhu, Pengzhi, additional, Huang, Yuzhe, additional, Huang, Hongxin, additional, Hu, Changming, additional, Huang, Wenyong, additional, Liang, Xiaoling, additional, and Lin, Haotian, additional

Published
2023
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8. DeepFundus: A flow-cytometry-like image quality classifier for boosting the whole life cycle of medical artificial intelligence

Author

Liu, Lixue, primary, Wu, Xiaohang, additional, Lin, Duoru, additional, Zhao, Lanqin, additional, Li, Mingyuan, additional, Yun, Dongyuan, additional, Lin, Zhenzhe, additional, Pang, Jianyu, additional, Li, Longhui, additional, Wu, Yuxuan, additional, Lai, Weiyi, additional, Xiao, Wei, additional, Shang, Yuanjun, additional, Feng, Weibo, additional, Tan, Xiao, additional, Li, Qiang, additional, Liu, Shenzhen, additional, Lin, Xinxin, additional, Sun, Jiaxin, additional, Zhao, Yiqi, additional, Yang, Ximei, additional, Ye, Qinying, additional, Zhong, Yuesi, additional, Huang, Xi, additional, He, Yuan, additional, Fu, Ziwei, additional, Xiang, Yi, additional, Zhang, Li, additional, Zhao, Mingwei, additional, Qu, Jinfeng, additional, Xu, Fan, additional, Lu, Peng, additional, Li, Jianqiao, additional, Xu, Fabao, additional, Wei, Wenbin, additional, Dong, Li, additional, Dai, Guangzheng, additional, He, Xingru, additional, Yan, Wentao, additional, Zhu, Qiaolin, additional, Lu, Linna, additional, Zhang, Jiaying, additional, Zhou, Wei, additional, Meng, Xiangda, additional, Li, Shiying, additional, Shen, Mei, additional, Jiang, Qin, additional, Chen, Nan, additional, Zhou, Xingtao, additional, Li, Meiyan, additional, Wang, Yan, additional, Zou, Haohan, additional, Zhong, Hua, additional, Yang, Wenyan, additional, Shou, Wulin, additional, Zhong, Xingwu, additional, Yang, Zhenduo, additional, Ding, Lin, additional, Hu, Yongcheng, additional, Tan, Gang, additional, He, Wanji, additional, Zhao, Xin, additional, Chen, Yuzhong, additional, Liu, Yizhi, additional, and Lin, Haotian, additional

Published
2023
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9. Optical coherence tomography angiography for the characterisation of retinal microvasculature alterations in pregnant patients with anaemia: a nested case‐control study

Author

Wu, Yuxuan, Wang, Dongyu, Wu, Xiaohang, Shen, Lixia, Zhao, Lanqin, Wang, Wei, Xiao, Hui, Wang, Xun, Liu, Lixue, Lin, Zhenzhe, Yang, Jingyuan, Lin, Xiaohong, Yun, Dongyuan, Iao, Wai Cheng, Wu, Yi, Xu, Miaohong, Song, Kexin, Xu, Zemeihong, Huang, Yihong, Shi, Shaole, Zhang, Mo, Zhou, Junling, Yang, Zhuofan, Wang, Zilian, and Lin, Haotian

Abstract

AimsTo characterise retinal microvascular alterations in the eyes of pregnant patients with anaemia (PA) and to compare the alterations with those in healthy controls (HC) using optical coherence tomography angiography (OCTA).MethodsThis nested case‐control study included singleton PA and HC from the Eye Health in Pregnancy Study. Fovea avascular zone (FAZ) metrics, perfusion density (PD) in the superficial capillary plexus, deep capillary plexus and flow deficit (FD) density in the choriocapillaris (CC) were quantified using FIJI software. Linear regressions were conducted to evaluate the differences in OCTA metrics between PA and HC. Subgroup analyses were performed based on comparisons between PA diagnosed in the early or late trimester and HC.ResultsIn total, 99 eyes of 99 PA and 184 eyes of 184 HC were analysed. PA had a significantly reduced FAZ perimeter (βcoefficient=−0.310, p<0.001), area (βcoefficient=−0.121, p=0.001) and increased circularity (βcoefficient=0.037, p<0.001) compared with HC. Furthermore, higher PD in the central (βcoefficient=0.327, p=0.001) and outer (βcoefficient=0.349, p=0.007) regions were observed in PA. PA diagnosed in the first trimester had more extensive central FD (βcoefficient=4.199, p=0.003) in the CC, indicating impaired perfusion in the CC.ConclusionIt was found that anaemia during pregnancy was associated with macular microvascular abnormalities, which differed in PA as pregnancy progressed. The results suggest that quantitative OCTA metrics may be useful for risk evaluation before clinical diagnosis.Trial registration numbers2021KYPJ098 and ChiCTR2100049850.

Published
2024
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10. Optical coherence tomography angiography for the characterisation of retinal microvasculature alterations in pregnant patients with anaemia: a nested case‒control study

Author

Wu, Yuxuan, primary, Wang, Dongyu, additional, Wu, Xiaohang, additional, Shen, Lixia, additional, Zhao, Lanqin, additional, Wang, Wei, additional, Xiao, Hui, additional, Wang, Xun, additional, Liu, Lixue, additional, Lin, Zhenzhe, additional, Yang, Jingyuan, additional, Lin, Xiaohong, additional, Yun, Dongyuan, additional, Iao, Wai Cheng, additional, Wu, Yi, additional, Xu, Miaohong, additional, Song, Kexin, additional, Xu, Zemeihong, additional, Huang, Yihong, additional, Shi, Shaole, additional, Zhang, Mo, additional, Zhou, Junling, additional, Yang, Zhuofan, additional, Wang, Zilian, additional, and Lin, Haotian, additional

Published
2022
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11. Spatial Technology Assessment of Green Space Exposure and Myopia

Author

Yang, Yahan, Chen, Wenben, Xu, Andi, Zhao, Lanqin, Ding, Xiaohu, Li, Jiawei, Zhu, Yi, Chen, Chuan, Long, Erping, Liu, Zhenzhen, Wang, Xun, Li, Xuelong, Zhang, Xingying, Jiang, Zhiyu, He, Huagui, Wang, Guojun, Jin, Ling, Liao, Huipeng, Yun, Dongyuan, Yu-Wai-Man, Patrick, Yan, Pisong, Wang, Ruixin, Li, Zhongwen, Xie, Yi, Liu, Yuantao, Wang, Xiaodan, Zhang, Qingling, Wang, Jiantao, Nie, Danyao, Zhang, Shaochong, Ting, Daniel Shu Wei, Wong, Tien Yin, He, Mingguang, Liu, Yizhi, Morgan, Ian George, and Lin, Haotian

Published
2022
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12. Effectiveness of an Ophthalmic Hospital-Based Virtual Service during the COVID-19 Pandemic

Author

Wu, Xiaohang, Chen, Jingjing, Yun, Dongyuan, Yuan, Meng, Liu, Zhenzhen, Yan, Pisong, Sim, Dawn A., Zhu, Yi, Chen, Chuan, Hu, Weiling, Wu, Zijian, Lin, Huaide, Wang, Yandong, Wu, Yanling, Chen, Mingfei, Zhang, Caoxian, Zheng, Yongxin, Liu, Xialin, Zhong, Xingwu, Diao, Hongxing, Wei Ting, Daniel Shu, Gunasekeran, Dinesh Visva, Li, Yongqiang, Zhang, Jie, Cai, Yaobin, Lao, Zhihao, Liu, Yizhi, Wong, Tien Yin, Lin, Xiaofeng, and Lin, Haotian

Published
2021
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13. Blockchain Technology for Ophthalmology: Coming of Age?

Author

Ng, Wei Yan, primary, Tan, Tien-En, additional, Xiao, Zhe, additional, Movva, Prasanth V.H., additional, Foo, Fuji S.S., additional, Yun, Dongyuan, additional, Chen, Wenben, additional, Wong, Tien Yin, additional, Lin, Hao Tian, additional, and Ting, Daniel S.W., additional

Published
2021
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14. Effectiveness of an ophthalmic hospital-based virtual service during COVID-19

Author

Wu, Xiaohang, Chen, Jingjing, Yun, Dongyuan, Yuan, Meng, Liu, Zhenzhen, Yan, Pisong, Sim, Dawn A., Zhu, Yi, Chen, Chuan, Hu, Weiling, Wu, Zijian, Lin, Huaide, Wang, Yandong, Wu, Yanling, Chen, Mingfei, Zhang, Caoxian, Zheng, Yongxin, Liu, Xialin, Zhong, Xingwu, Diao, Hongxing, Wei Ting, Daniel Shu, Gunasekeran, Dinesh Visva, Li, Yongqiang, Zhang, Jie, Cai, Yaobin, Lao, Zhihao, Liu, Yizhi, Wong, Tien Yin, Lin, Xiaofeng, and Lin, Haotian

Subjects
Adult, Male, China, Adolescent, Eye Diseases, SARS-CoV-2, COVID-19, Middle Aged, Hospitals, Special, Telemedicine, Ophthalmology, Young Adult, Treatment Outcome, Humans, Female, Delivery of Health Care, Physical Examination, Reports
Abstract

The management of ophthalmic diseases in the virtual hospital can be implemented and is complementary to those of on-site F2F clinics. Virtual clinical service may be a useful model in the post-COVID-19 pandemic “new normal”.

Published
2020

15. Associations Between Regional Environment and Cornea-Related Morphology of the Eye in Young Adults: A Large-Scale Multicenter Cross-Sectional Study

Author

Ma, Jiaonan, primary, Zhao, Lanqin, additional, Yang, Yahan, additional, Yun, Dongyuan, additional, Yu-Wai-Man, Patrick, additional, Zhu, Yi, additional, Chen, Chuan, additional, Li, Ji-Peng Olivia, additional, Li, Mengdi, additional, Zhang, Yan, additional, Cui, Tingxin, additional, Meng, Xiangbing, additional, Zhang, Lin, additional, Zhang, Jiamei, additional, Song, Yi, additional, Lei, Yulin, additional, Liu, Jianguo, additional, Huangfu, Xiaojin, additional, Jiang, Li, additional, Cai, Jinfeng, additional, Wu, Huiying, additional, Shang, Liqiang, additional, Wen, Dan, additional, Yi, Xianglong, additional, Li, Xin, additional, Xiao, Jing, additional, He, Rui, additional, Yang, Yang, additional, Yang, Jun, additional, Cheng, George P. M., additional, Bai, Ji, additional, Zhong, Xingwu, additional, Guo, Hua, additional, Yan, Pisong, additional, Wang, Yan, additional, and Lin, Haotian, additional

Published
2021
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18. Development and Evaluation of a Deep Learning System for Screening Retinal Hemorrhage Based on Ultra-Widefield Fundus Images

Author

Li, Zhongwen, primary, Guo, Chong, additional, Nie, Danyao, additional, Lin, Duoru, additional, Zhu, Yi, additional, Chen, Chuan, additional, Xiang, Yifan, additional, Xu, Fabao, additional, Jin, Chenjin, additional, Zhang, Xiayin, additional, Yang, Yahan, additional, Zhang, Kai, additional, Zhao, Lanqin, additional, Zhang, Ping, additional, Han, Yu, additional, Yun, Dongyuan, additional, Wu, Xiaohang, additional, Yan, Pisong, additional, and Lin, Haotian, additional

Published
2020
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19. Implementation, Characteristics, and Effectiveness of an Ophthalmic Hospital-Based Virtual Clinical Service in China During COVID-19

Author

Wu, Xiaohang, primary, Chen, Jingjing, additional, Yun, Dongyuan, additional, Yuan, Meng, additional, Liu, Zhenzhen, additional, Yan, Pisong, additional, Zhu, Yi, additional, Chen, Chuan, additional, Hu, Weiling, additional, Wu, Zijian, additional, Lin, Huaide, additional, Wang, Yandong, additional, Wu, Yanling, additional, Chen, Mingfei, additional, Zhang, Caoxian, additional, Zheng, Yongxin, additional, Liu, Xialin, additional, Zhong, Xingwu, additional, Diao, Hongxing, additional, Ting, Daniel Shu Wei, additional, Visva Gunasekeran, Dinesh, additional, Li, Yongqiang, additional, Zhang, Jie, additional, Cai, Yaobin, additional, Lao, Zhihao, additional, Liu, Yizhi, additional, Wong, Tien Yin, additional, Lin, Haotian, additional, and Lin, Xiaofeng, additional

Published
2020
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21. Shaping school for childhood myopia: the association between floor area ratio of school environment and myopia in China.

Author

Zeng D, Yang Y, Tang Y, Zhao L, Wang X, Yun D, Chen W, Shang Y, Xu A, Liao H, Zhang X, Lin D, and Lin H

Subjects
Humans, Male, Child, Female, China epidemiology, Prospective Studies, Incidence, Risk Factors, Follow-Up Studies, Myopia epidemiology, Schools, Refraction, Ocular physiology
Abstract

Aim: To investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset., Methods: This prospective cohort study recruited 136 753 children aged 6-10 years from 108 schools in Shenzhen, China at baseline (2016-2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR was objectively evaluated using geographical information system technology. Mixed-effects logistic regression models were constructed to examine the association of FAR with a 2-year cumulative incidence of myopia among individuals without baseline myopia; multiple linear regression model, with a 2-year cumulative incidence rate of myopia at each school., Results: Of 101 624 non-myopic children (56.3% boys; mean (SE) age, 7.657±1.182 years) included in the study, 26 391 (26.0%) of them developed myopia after 2 years. In the individual-level analysis adjusting for demographic, socioeconomic and greenness factors, an IQR in FAR was associated with a decreased risk of 2-year myopia incidence (OR 0.898, 95% CI 0.866 to 0.932, p<0.001). Similar findings were observed in the analysis additionally adjusted for genetic and behavioural factors (OR 0.821, 95% CI 0.766 to 0.880, p<0.001). In the school-level, an IQR increase in FAR was found to be associated with a 2.0% reduction in the 2-year incidence rate of myopia (95% CI 1.3% to 2.6%, p<0.001)., Conclusions: Exposure to higher FAR was associated with a decreased myopia incidence, providing insights into myopia prevention through school built environments in China., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.)

Published
2024
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22. Optical coherence tomography angiography for the characterisation of retinal microvasculature alterations in pregnant patients with anaemia: a nested case‒control study.

Author

Wu Y, Wang D, Wu X, Shen L, Zhao L, Wang W, Xiao H, Wang X, Liu L, Lin Z, Yang J, Lin X, Yun D, Iao WC, Wu Y, Xu M, Song K, Xu Z, Huang Y, Shi S, Zhang M, Zhou J, Yang Z, Wang Z, and Lin H

Subjects
Humans, Pregnancy, Female, Case-Control Studies, Fluorescein Angiography methods, Microvessels diagnostic imaging, Retinal Vessels diagnostic imaging, Tomography, Optical Coherence methods
Abstract

Aims: To characterise retinal microvascular alterations in the eyes of pregnant patients with anaemia (PA) and to compare the alterations with those in healthy controls (HC) using optical coherence tomography angiography (OCTA)., Methods: This nested case‒control study included singleton PA and HC from the Eye Health in Pregnancy Study. Fovea avascular zone (FAZ) metrics, perfusion density (PD) in the superficial capillary plexus, deep capillary plexus and flow deficit (FD) density in the choriocapillaris (CC) were quantified using FIJI software. Linear regressions were conducted to evaluate the differences in OCTA metrics between PA and HC. Subgroup analyses were performed based on comparisons between PA diagnosed in the early or late trimester and HC., Results: In total, 99 eyes of 99 PA and 184 eyes of 184 HC were analysed. PA had a significantly reduced FAZ perimeter ( β coefficient=-0.310, p<0.001), area ( β coefficient=-0.121, p=0.001) and increased circularity ( β coefficient=0.037, p<0.001) compared with HC. Furthermore, higher PD in the central ( β coefficient=0.327, p=0.001) and outer ( β coefficient=0.349, p=0.007) regions were observed in PA. PA diagnosed in the first trimester had more extensive central FD ( β coefficient=4.199, p=0.003) in the CC, indicating impaired perfusion in the CC., Conclusion: It was found that anaemia during pregnancy was associated with macular microvascular abnormalities, which differed in PA as pregnancy progressed. The results suggest that quantitative OCTA metrics may be useful for risk evaluation before clinical diagnosis., Trial Registration Numbers: 2021KYPJ098 and ChiCTR2100049850., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2023
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