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In order to detect an indicator of the onset of pubertal spurt, the DHEAS serie levels were correlated with age, weight, height, skeletal maturity stage (Hägg and Taranger) and sexual maturity (Tanner and, Prader). 33 patients; 18 males and 15 females, between 8 and 12 years old were studied. Healthy children in Tanner I sexual maturity stage was the research criteria for inclusion. The data were taken every six months during three years (2000-2002). The behavior of the anthropometric variables of the general population was published in a previous paper. In the group of males, we did not found any significant correlation between the seric levels of DHEAS with the studied variables, except for the weight at the beginning of the study. In the female group, a correlation was found with the ulnar sesamoid although not in the long term, and with the weight in the middle of the study. However, none of these associations and correlations confirmed our initial hypothesis because the correlations found were considerate such as isolated facts. RESUMEN: Con el fin de detectar un indicador del inicio del brote puberal se correlacionaron los niveles séricos de DHEAS con la edad, el peso, la talla, el estadio de desarrollo esquelético (Hägg y Taranger) y el de la maduración sexual (Tanner y orquidiometría de Prader). Se estudiaron 33 pacientes, 18 de sexo masculino y 15 de sexo femenino, entre los 8 y los 11 años de edad; el criterio de inclusión fue el de niños sanos con un estadio de maduración sexual de Tanner I. La toma de muestras se realizó cada seis meses durante tres años (2000-2002). El comportamiento de las variables antropométricas de la población general se publicó en el artículo de IGF-1 previo. En el grupo de niños no se observó ninguna correlación significativa entre el nivel de DHEAS con ninguna variable, excepto para el peso al inicio del estudio. En el grupo de niñas, la correlación se dio con el sesamoideo, aunque no fue a largo plazo y con el peso en la mitad del estudio. Sin embargo, ninguna de estas asociaciones y correlaciones confirma nuestra hipótesis inicial, ya que todas estas asociaciones fueron aisladas.

The objective of this study was to determine which of the methods used to establish the skeletal maturation is better related with the maturity of the patient, and for that reason is more practical and applicable to the clinical practice. The relationship between three different methods for evaluating the skeletal maturation through the hand-wrist film (Taranger and Hägg, Greulich and Pyle, and Fishman) and the sexual maturity (Tanner and Prader) was searched. A total of 33 patients were studied: 18 male and 15 female, between 8 and 13 years. Healthy children in Tanner I sexual maturity stage was the research criterion for inclusion. The 100% of both samples (masculine and feminine) were located in the F stage of skeletal development. Data were taken every six months during the course of three years (2000- 2002). In the male population there were no associations between the skeletal maturation evaluated according to Greulich and Pyle´s method, and Fishman´s method with the sexual maturity. On the other hand, an association was found between Taranger and Hägg´s method and the sexual maturity (sesamoid-general Tanner during the fourth sample and the middle phalanx of the third finger- right testicular volume during the same sample, as happened with the middle phalanx with both testicular volumes during de fifth sample). In the female population there were statistically significant associations between Fishman´s method and the sexual maturity during the second and sixth samples; also between Greulich and Pyle´s evaluation and the sexual maturity during the sixth sample. There was also an association between Taranger and Hägg´s method in the second, third and sixth samples (sesamoid-Tanner, middle phalanx-Tanner and sesamoid-Tanner respectively).