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10 results on '"Zarkadas, Anastasios"'

2. A Brief Overview of Cholinergic and Phosphodiesterase-5 Inhibitors in Diabetic Bladder Dysfunction.

Author

Kallinikas, Georgios, Haronis, Georgios, Kallinika, Eirini, Kozyrakis, Diomidis, Rodinos, Evangelos, Filios, Athanasios, Filios, Panagiotis, Mityliniou, Despoina, Safioleas, Konstantinos, Zarkadas, Anastasios, Bozios, Dimitrios, Karmogiannis, Athanasios, Konstantinopoulos, Vasileios, Konomi, Anna Maria, Ektesabi, Amin M., and Tsoporis, James N.

Abstract

Diabetic bladder dysfunction (DBD) comprises a wide spectrum of lower urinary tract symptoms that impact diabetic patients' lives, including urinary frequency, urgency, incontinence, and incomplete bladder emptying. To relieve symptoms, anticholinergics have been widely prescribed and are considered an effective treatment. There is increasing evidence that diabetic patients may benefit from the use of phosphodiesterase 5 (PDE5) inhibitors. This narrative review aims to provide a brief overview of the pathophysiology of DBD along with a focus on cholinergic and phosphodiesterase inhibitors as therapies that benefit DBD. An examination of the literature suggests compelling avenues of research and underscores critical gaps in understanding the mechanisms underlying DBD. New tools and models, especially rodent models, are required to further elucidate the mechanisms of action of current therapies in the treatment of DBS. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Renal artery infarction in the SARS-Cov-2 era: A systematic review of case reports

Author

Kozyrakis, Diomidis, primary, Kallinikas, Georgios, additional, Zarkadas, Anastasios, additional, Bozios, Dimitris, additional, Konstantinopoulos, Vasileios, additional, Charonis, Georgios, additional, Safioleas, Konstantinos, additional, Filios, Athanasios, additional, Rodinos, Evangelos, additional, Mytiliniou, Despoina, additional, Vlassopoulos, Gerasimos, additional, Gkerzelis, Ioannis, additional, and Filios, Panagiotis, additional

Published
2023
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5. Prognostic factors for the safety and efficacy of retrograde laser lithotripsy: Data from a contemporary series of 155 consecutive patients with single and multiple lithiasis of the urinary tract

Author

Kozyrakis, Diomidis, primary, Soukias, Georgios, additional, Karagiannis, Dimitrios, additional, Zarkadas, Anastasios, additional, Perikleous, Stefanos, additional, Chatzistamou, Styliani-Elissavet, additional, Katsaros, Ilias, additional, Skriapas, Konstantinos, additional, Lardas, Michael, additional, Mertziotis, Nikolaos, additional, and Kratiras, Zisis, additional

Published
2022
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8. Clinical Outcome and Prognostic Factors of Sepsis, Septic Shock and Prolonged Hospitalization, of Patients Presented with Acute Obstructive Pyelonephritis

Author

Kozyrakis, Diomidis, primary, Kratiras, Zisis, additional, Soukias, Georgios, additional, Chatzistamou, Styliani-Elissavet, additional, Zarkadas, Anastasios, additional, Perikleous, Stefanos, additional, Kateris, Dimitris, additional, Katsaros, Ilias, additional, Skriapas, Konstantinos, additional, and Karagiannis, Dimitrios, additional

Published
2020
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9. The Current Role of Osteoclast Inhibitors in Patients with Prostate Cancer

Author

Kozyrakis, Diomidis, Paridis, Dionyssios, Perikleous, Stefanos, Malizos, Konstantinos, Zarkadas, Anastasios, and Tsagkalis, Antonios

Subjects
Article Subject
Abstract

Purpose. Prostate cancer (PCa) is one of the most frequently diagnosed malignancies worldwide. Hormonal deprivation therapy is a well-established treatment for locally advanced or metastatic diseases but exposes patients to the risk of osteoporosis and fragility fractures. Furthermore, the tropism of the PCa cells to osseous metastases increases the incidence of skeletal-related events (SREs). Methods. A nonsystematic review of the international literature was performed in respect to the use of osteoclast inhibitors zoledronic acid (ZA) and denosumab (DEN) in PCa patients. Results. DEN and ZA have proved their efficacy in preventing osteoporosis and bone mass loss in patients treated with hormonal therapy with no proven superiority of one agent over the other. However, the effectiveness in reducing fragility fractures has been proved only for DEN so far. In metastatic-free castrate-sensitive high-risk PCa patients, ZA has not shown any efficacy in preventing osseous metastasis, and evidence is lacking in favor or against the use of DEN. The use of osteoclasts inhibitors had no evident positive effect in overall and disease-specific survival in this group of patients. In advanced castrate-refractory malignancy, DEN has shown clinical superiority over ZA in preventing new SRE but not in overall survival. Conclusion. Superiority of DEN over ZA has been proved only in advanced castrate refractory disease in terms of preventing new SRE. In the rest of the cases, the selection of either agent should be based on the clinical condition of each patient and the cost of the treatment.

Published
2018
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10. How Effective Is Retrograde Semirigid and Flexible Ureteroscopic Lithotripsy for the Treatment of Large Ureteral Stones Equal of or Greater than 15 mm? Results from a Single Center

Author

Kozyrakis, Diomidis G., primary, Kratiras, Zisis K., additional, Perikleous, Stefanos K., additional, Zarkadas, Anastasios P., additional, Chatzistamoy, Styliani-Elissavet E., additional, Karagiannis, Dimitrios K., additional, and Solinis, Ioannis T., additional

Published
2019
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