189 results on '"Zaugg, Judith B"'
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2. Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension
3. Basis of gene-specific transcription regulation by the Integrator complex
4. MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention
5. The remission status of AML patients after allo-HCT is associated with a distinct single-cell bone marrow T-cell signature
6. Convolutional networks for supervised mining of molecular patterns within cellular context
7. APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation
8. Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition
9. Genome-wide quantification of transcription factor binding at single-DNA-molecule resolution using methyl-transferase footprinting
10. Enhancers in disease: molecular basis and emerging treatment strategies
11. Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease
12. HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling
13. Landscape of cohesin-mediated chromatin loops in the human genome
14. Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy
15. Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML
16. PB1790: LOOKING ‘BENEATH’ THE SURFACE: PROTEOMICS AND GLYCIPROTEOMICS REVEAL NOVEL TARGETS FOR CAR-T CELL THERAPIES IN ACUTE MYELOID LEUKEMIA (AML)
17. P1206: A SINGLE-CELL MULTI-OMIC AND SPATIAL ATLAS OF NODAL B CELL NON-HODGKIN LYMPHOMAS REVEALS PLASTICITY IN B CELL MATURATION AS A DRIVER OF INTRATUMOR HETEROGENEITY
18. P1218: A REPROGRAMMING OF THE LYMPH NODE MICROENVIRONMENT UNDERLIES LOSS OF COMPARTMENTALISATION IN AGGRESSIVE LYMPHOMAS
19. Histone H3.3 lysine 9 and 27 control repressive chromatin states at cryptic cis-regulatory elements and bivalent promoters in mouse embryonic stem cells
20. GRaNIE and GRaNPA : inference and evaluation of enhancer‐mediated gene regulatory networks
21. Structure meets function: How chromatin organisation conveys functionality
22. Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension
23. Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions
24. The impact of rare variation on gene expression across tissues
25. Dynamic landscape and regulation of RNA editing in mammals
26. Landscape of X chromosome inactivation across human tissues
27. Operation of a TCA cycle subnetwork in the mammalian nucleus
28. Drug-microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL
29. Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline
30. Operation of a TCA cycle subnetwork in the mammalian nucleus
31. Comparative chromatin accessibility upon BDNF stimulation delineates neuronal regulatory elements
32. Drug‐microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL
33. Genetic effects on gene expression across human tissues
34. Extensive Variation in Chromatin States Across Humans
35. Influence of the bleaching interval on the luminosity of long-term discolored enamel-dentin discs
36. Gene Loops Enhance Transcriptional Directionality
37. CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia
38. GRaNIE and GRaNPA: Inference and evaluation of enhancer-mediated gene regulatory networks applied to study macrophages
39. Enhancer-priming in ageing human bone marrow mesenchymal stromal cells contributes to immune traits
40. Transcription factors: Bridge between cell signaling and gene regulation
41. Combinatorial drug-microenvironment interaction mapping reveals cell-extrinsic drug resistance mechanisms and clinically relevant patient subgroups in CLL
42. Donor cell memory confers a metastable state of directly converted cells
43. MYT1Lhaploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention
44. Comparative chromatin accessibility upon BDNF-induced neuronal activity delineates neuronal regulatory elements
45. Role of histone modifications and early termination in pervasive transcription and antisense-mediated gene silencing in yeast
46. Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis
47. Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Foetal Liver and Bone Marrow Haematopoiesis
48. Operation of a TCA cycle subnetwork in the mammalian nucleus
49. Predictive features of gene expression variation reveal mechanistic link with differential expression
50. APOBEC2 is a Transcriptional Repressor required for proper Myoblast Differentiation
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