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1. Epidemiological Surveillance Reveals the Rise and Establishment of the Omicron SARS-CoV-2 Variant in Brazil

Author

Silva, Joice do Prado, primary, Lima, Aline Brito de, additional, Alvim, Luige Biciati, additional, Malta, Frederico Scott Varella, additional, Mendonça, Cristiane Pinheiro Toscano Brito, additional, Carvalho, André Henrique Barbosa de, additional, Rios, Jéssica Silqueira Hickson, additional, Fonseca, Paula Luize Camargos, additional, Queiroz, Daniel Costa, additional, Santos, Luíza Campos Guerra de Araújo e, additional, Ferreira, Alessandro Clayton de Souza, additional, Souza, Renan Pedra de, additional, Aguiar, Renato Santana de, additional, and Zauli, Danielle Alves Gomes, additional

Published
2023
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2. The Omicron Lineages BA.1 and BA.2 (Betacoronavirus SARS-CoV-2) Have Repeatedly Entered Brazil through a Single Dispersal Hub

Author

Lamarca, Alessandra P., primary, Souza, Ueric José Borges de, additional, Moreira, Filipe Romero Rebello, additional, Almeida, Luiz G. P. de, additional, Menezes, Mariane Talon de, additional, Souza, Adrieli Barboza de, additional, Ferreira, Alessandro Clayton de Souza, additional, Gerber, Alexandra L., additional, Lima, Aline B. de, additional, Guimarães, Ana Paula de C., additional, Cavalcanti, Andréa Cony, additional, Silva, Aryel B. Paz e, additional, Lima, Bruna Israel, additional, Lobato, Cirley, additional, Silva, Cristiane Gomes Da, additional, Mendonça, Cristiane P. T. B., additional, Queiroz, Daniel Costa, additional, Zauli, Danielle Alves Gomes, additional, Menezes, Diego, additional, Possebon, Fábio Sossai, additional, Cardoso, Franciano Dias Pereira, additional, Malta, Frederico Scott Varella, additional, Braga-Paz, Isabela, additional, Silva, Joice do Prado, additional, Ferreira, Jorge Gomes Goulart, additional, Galvão, Jucimária Dantas, additional, Souza, Leandro Magalhães de, additional, Ferreira, Leonardo, additional, Possuelo, Lia Gonçalves, additional, Cavalcante, Liliane Tavares de Faria, additional, Alvim, Luige B., additional, Souza, Luiz Fellype Alves de, additional, Santos, Luiza C. G. de Araújo E, additional, Dias, Rillery Calixto, additional, Souza, Rutilene Barbosa, additional, Castro, Thaís Regina y, additional, Valim, Andréia Rosane de Moura, additional, Campos, Fabrício Souza, additional, Araujo, João Pessoa, additional, Trindade, Priscila de Arruda, additional, Aguiar, Renato S., additional, Michael Delai, Robson, additional, and Vasconcelos, Ana Tereza R de, additional

Published
2023
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3. Dynamics of Early Establishment of SARS-CoV-2 VOC Omicron Lineages in Minas Gerais, Brazil

Author

de Menezes, Mariane Talon, primary, Moreira, Filipe Romero Rebello, additional, Whittaker, Charles, additional, Santos, Franciele Martins, additional, Queiroz, Daniel Costa, additional, Geddes, Victor, additional, Fonseca, Paula Luize Camargos, additional, de Jesus, Jaqueline Góes, additional, Mendes-Oliveira, Franciane, additional, Reis-Souza, Valquíria, additional, Santos, Bibiana, additional, Zauli, Danielle Alves Gomes, additional, de Lima, Aline Brito, additional, de Brito Mendonça, Cristiane, additional, Alvim, Luige Biciati, additional, do Prado Silva, Joice, additional, Malta, Frederico Scott Varella, additional, de Souza Ferreira, Alessandro Clayton, additional, Faria, Nuno R., additional, Sabino, Ester Cerdeira, additional, and Aguiar, Renato Santana, additional

Published
2023
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5. Monitoring the Establishment of VOC Gamma in Minas Gerais, Brazil: A Retrospective Epidemiological and Genomic Surveillance Study

Author

Alves, Hugo José, primary, de Araújo, João Locke Ferreira, additional, Fonseca, Paula Luize Camargos, additional, Moreira, Filipe Romero Rebello, additional, Bonfim, Diego Menezes, additional, Queiroz, Daniel Costa, additional, Miguita, Lucyene, additional, de Souza, Rafael Marques, additional, Geddes, Victor Emmanuel Viana, additional, Costa, Walyson Coelho, additional, Oliveira, Jaqueline Silva de, additional, Medeiros, Eva Lídia Arcoverde, additional, Souza, Carolina Senra Alves de, additional, Saliba, Juliana Wilke, additional, Menezes, André Luiz, additional, Oliveira, Eneida Santos de, additional, Adelino, Talita Emile Ribeiro, additional, Guimaraes, Natalia Rocha, additional, Ribeiro, Adriana Aparecida, additional, Moreira, Rennan Garcias, additional, Zauli, Danielle Alves Gomes, additional, Silva, Joice do Prado, additional, Malta, Frederico Scott Varella, additional, Ferreira, Alessandro Clayton de Souza, additional, Silva, Ana Valesca Fernandes Gilson, additional, Alfenas-Zerbini, Poliane, additional, Souza, Flavia Oliveira de, additional, Sabino, Adriano de Paula, additional, Xavier, Laura do Amaral, additional, Carobin, Natália Virtude, additional, Carvalho, Alex Fiorini de, additional, Lourenço, Karine Lima, additional, Teixeira, Santuza Maria Ribeiro, additional, Fernandes, Ana Paula Salles Moura, additional, Fonseca, Flavio Guimarães da, additional, Abrahão, Jônatas Santos, additional, Iani, Felipe Campos de Melo, additional, Rodrigues, Rodrigo Araújo Lima, additional, Souza, Renan Pedra de, additional, and Aguiar, Renato Santana, additional

Published
2022
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6. MICROBIAL CONTENT RECOVERED FROM DIABETIC FOOT INFECTIONS: A CROSS-SECTIONAL STUDY IN BRAZIL / CONTEÚDO MICROBIANO RECUPERADO EM INFECÇÕES DE PÉ DIABÉTICO: UM ESTUDO TRANSVERSAL NO BRASIL

Author

Francisco, Renata Barreto, primary, Vieira, Cristina Dutra, additional, Farias, Luiz de Macêdo, additional, Souza, Antônio Eustáquio de, additional, Castro, Bruno Lima de, additional, Braga, Renato Rivail Rodrigues, additional, Zauli, Danielle Alves Gomes, additional, Carvalho, Maria Auxiliadora Roque de, additional, and Santos, Simone Gonçalves dos, additional

Published
2020
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7. Inflammatory and Pro-resolving Mediators in Frontotemporal Dementia and Alzheimer’s Disease

Author

Fraga, Vanêssa Gomes, primary, Magalhães, Carolina Antunes, additional, Loures, Cristina de Mello Gomide, additional, de Souza, Leonardo Cruz, additional, Guimarães, Henrique Cerqueira, additional, Zauli, Danielle Alves Gomes, additional, Carvalho, Maria das Graças, additional, Ferreira, Cláudia Natália, additional, Caramelli, Paulo, additional, de Sousa, Lirlândia Pires, additional, and Gomes, Karina Braga, additional

Published
2019
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8. Sexually Transmitted Infections Detected by Multiplex Real Time PCR in Asymptomatic Women and Association with Cervical Intraepithelial Neoplasia

Author

Lima, Luiza de Miranda, additional, Hoelzle, Carolina René, additional, Simões, Renata Toscano, additional, Lima, Maria Inês de Miranda, additional, Fradico, Jordana Rodrigues Barbosa, additional, Mateo, Elvis Cristian Cueva, additional, Zauli, Danielle Alves Gomes, additional, and Melo, Victor Hugo, additional

Published
2018
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10. Divergent cerebrospinal fluid cytokine network induced by non-viral and different viral infections on the central nervous system

Author

Bastos, Michele Souza, primary, Coelho-dos-Reis, Jordana Grazziela, additional, Zauli, Danielle Alves Gomes, additional, Naveca, Felipe Gomes, additional, Monte, Rossicleia Lins, additional, Pimentel, João Paulo, additional, Macário, Valéria Munique Kramer, additional, da Silva, Natália Lessa, additional, Peruhype-Magalhães, Vanessa, additional, Pascoal-Xavier, Marcelo Antônio, additional, Guimaraes, Allyson, additional, Carvalho, Andréa Teixeira, additional, Malheiro, Adriana, additional, Martins-Filho, Olindo Assis, additional, and Mourão, Maria Paula Gomes, additional

Published
2015
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12. Callithrix penicillata: A feasible experimental model for dengue virus infection

Author

Ferreira, Milene Silveira, primary, de Castro, Paulo Henrique Gomes, additional, Silva, Gilmara Abreu, additional, Casseb, Samir Mansur Moraes, additional, Dias Júnior, Antônio Gregório, additional, Rodrigues, Sueli Guerreiros, additional, Azevedo, Raimunda do Socorro da Silva, additional, Silva, Matheus Fernandes Costa e, additional, Zauli, Danielle Alves Gomes, additional, Araújo, Márcio Sobreira Silva, additional, Béla, Samantha Ribeiro, additional, Teixeira-Carvalho, Andréa, additional, Martins-Filho, Olindo Assis, additional, and Vasconcelos, Pedro Fernando da Costa, additional

Published
2014
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13. Gene expression profile of cytokines and chemokines in skin lesions from Brazilian Indians with localized cutaneous leishmaniasis

Author

Costa-Silva, Matheus Fernandes, primary, Gomes, Luciana Inácia, additional, Martins-Filho, Olindo Assis, additional, Rodrigues-Silva, Renata, additional, Freire, Janaína de Moura, additional, Quaresma, Patrícia Flávia, additional, Pascoal-Xavier, Marcelo Antônio, additional, Mendes, Tiago Antônio de Oliveira, additional, Serakides, Rogéria, additional, Zauli, Danielle Alves Gomes, additional, Campi-Azevedo, Ana Carolina, additional, Melo, Maria Norma, additional, Gontijo, Célia Maria Ferreira, additional, Peruhype-Magalhães, Vanessa, additional, and Teixeira-Carvalho, Andréa, additional

Published
2014
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14. Impact of Mitomycin C on the mRNA Expression Signatures of Immunological Biomarkers in Eosinophilic Nasal Polyposis

Author

de Castro, Mirian Cabral Moreira, primary, Rocha-Silva, Fabiana, additional, Gomes, Luciana Inácia, additional, Zauli, Danielle Alves Gomes, additional, Mourão, Marina de Moraes, additional, de Castro, Mariana Moreira, additional, Guimarães, Roberto Eustáquio Santos, additional, Teixeira-Carvalho, Andrea, additional, and Martins-Filho, Olindo Assis, additional

Published
2013
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15. Distribution, detection of enterotoxigenic strains and antimicrobial drug susceptibility patterns of Bacteroides fragilis group in diarrheic and non-diarrheic feces from Brazilian infants

Author

Ferreira, Débora Paula, primary, Silva, Vânia Lúcia, additional, Guimarães, Danielle Aparecida, additional, Coelho, Cíntia Marques, additional, Zauli, Danielle Alves Gomes, additional, Farias, Luiz Macêdo, additional, Carvalho, Maria Auxiliadora Roque, additional, and Diniz, Claudio Galuppo, additional

Published
2010
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16. Ocorrência de Escherichia coli comensal e diarreiogênica na microbiota fecal de crianças com e sem diarréia aguda e seu perfil de susceptibilidade a antimicrobianos

Author

Garcia, Patrícia Guedes, Diniz, Cláudio Galuppo, Silva, Vânia Lúcia da, Oliveira, Murilo Gomes, and Zauli, Danielle Alves Gomes

Subjects
Acute diarrhea, Diarréia aguda, CIENCIAS DA SAUDE [CNPQ], Microbiota fecal, Drug resistance, Fecal microbiota, E. coli, Resistência a drogas
Abstract

Diarréia aguda é um problema de saúde pública, causa importante de morbidade e mortalidade, sobretudo, em países em desenvolvimento. A etiologia das doenças diarréicas é variada e entre os patógenos bacterianos destacam-se as linhagens diarreiogênicas ou patotipos de Escherichia coli. Foi investigada a ocorrência de E. coli comensal ou diarreiogênica em 141 amostras fecais de crianças de zero até cinco anos de idade de origem comunitária em Juiz de Fora, MG. Dos espécimes, 84 foram provenientes de doadores com manifestação clínica de diarréia aguda (CD) e 57 de doadores clinicamente saudáveis, sem diarréia (SD). Após identificação e caracterização microbiana, foi determinado o seu perfil de susceptibilidade a antimicrobianos. As linhagens bacterianas foram identificadas fenotípica e genotipicamente por métodos bioquímicos clássicos e moleculares, respectivamente, e a caracterização dos patotipos de interesse no trato gastrintestinal foi feita por metodologia molecular. O perfil de susceptibilidade a antimicrobianos foi determinado pelo método de Kirby-Bauer, segundo recomendações do CLSI (2007). Considerando-se todo o grupo amostral, 136 linhagens de E. coli foram recuperadas de fezes CD (36,8% diarreiogências) e 84 de fezes SD (30,9% diarreiogênicas). A confirmação da identificação bioquímica por metodologia molecular mostrou uma correlação de 97,3% entre as duas metodologias. E. coli enteroagregativa (EAEC) foi o patotipo mais freqüentemente recuperado no grupo CD (16,2%) e o único isolado no grupo SD (30,9%). E. coli enteropatogênica (EPEC) atípica foi o segundo patotipo mais isolado no grupo CD (10,3%), seguido de E. coli produtora de toxina Shiga (STEC) (7,4%) e E. coli enterotoxigênica (ETEC) (2,9%). Nenhuma linhagem de EPEC típica e E. coli enteroinvasiva (EIEC) foi recuperada. A investigação do perfil de susceptibilidade aos antimicrobianos demonstra elevada resistência a fármacos, como ampicilina, tetraciclina e sulfametoxazol-trimetoprim, enquanto que resistência intermediária foi observada contra a ampicilina/sulbactam, cefalotina, tetraciclina e amicacina e gentamicina. Os antimicrobianos mais eficazes foram ceftazidima, ceftriaxona, imipenem e piperacilina/tazobactan, para os quais não foi verificada resistência bacteriana. A diferenciação entre os patotipos de E. coli é de grande importância, uma vez que estes microrganismos estão implicados em diarréias agudas em crianças e, quase sempre, necessitarão de tratamento medicamentoso. De maneira geral, nossos resultados indicam a relevância da participação de agentes bacterianos diarreiogênicos na gênese da diarréia aguda na infância, em crianças de 0 a 5 anos. A alta resistência a antimicrobianos observada em nosso trabalho suscita uma ampla discussão sobre uso indiscriminado/indevido de antibióticos e os riscos inerentes da automedicação. Acute diarrhea is a public health problem, important cause of morbidity and mortality, especially in developing countries. The etiology is varied and considering the bacterial pathogens, the diarrheagenic Escherichia coli pathotypes are among the most important. In this study we have investigated the occurrence of commensal or diarrheagenic E. coli in 141 fecal samples from children of zero to five years of age in Juiz de Fora, MG. Of the specimens, 84 were obtained from clinically injured donors with acute diarrhea (CD) and 57 from clinically healthy donors without diarrhea (SD). After microbial identification and characterization the bacterial antimicrobial susceptibility patterns were determined. The bacterial strains were phenotipically and genotipically indentified by conventional biochemical methods and molecular approach, respectively. The E. coli pathotypes were also genetically characterized by molecular methodology. The antimicrobial susceptibility patterns were determined by the Kirby-Bauer method, according to the CLSI guidelines (2007). Considering all fecal specimens, 136 E. coli strains were isolated and identified (36.8%, CD) and 84 (30.9%, SD). Confirmation of identification by molecular approach showed 97,3% of correlation between the two methodologies. Enteroaggregative E. coli (EAEC) was the most frequently recovered pathotype identified in the acute diarrhea group (16.2%) whereas the only recovered pathotype identified in the feces from healthy donors (30.9%). Enteropathogenic E. coli (EPEC) was the second most isolated pathotype group (10.3%), followed by STEC (7.4%) and ETEC (2.9%). No typical EPEC or EIEC strains were recovered. The antimicrobial susceptibility patterns shown high antimicrobial resistance rates against ampicillin, tetracycline, and sulfamethoxazole-trimethoprim. Intermediary resistance was observed against ampicillin/sulbactam, cefalotin, tetracycline, amikacin and gentamicin. The most effective antimicrobials were ceftazidime ceftriaxone, imipenem and piperacillin/tazobactam, for which no bacterial resistance was observed. The differentiation between the diarrheagenic E. coli pathotypes is of great importance, since they are involved in acute diarrheal diseases in children and, almost often will require antimicrobial chemotherapy. Overall, our results may indicate the importance of the bacterial agents in the etiology of diarrheic diseases in childhood, mainly considering children of 0 to 5 years. The high antimicrobial resistance observed in our study raises a broad discussion on the indiscriminate or improper use of antimicrobials, besides the risks of self-medication.

Published
2009

17. Oropouche virus genomic surveillance in Brazil.

Author

Moreira FRR, Dutra JVR, de Carvalho AHB, Reis CR, Rios JSH, Ribeiro MO, Arruda MB, Alvarez P, Souza RP, Voloch C, Zauli DAG, and Aguiar RS

Abstract

Competing Interests: We declare no competing interests. All new Oropouche virus genome sequences were deposited on NCBI GenBank under accessions PQ066768 to PQ066785. We acknowledge all authors who submitted Oropouche virus genome sequences to National Center for Biotechnology Information GenBank, making this and other genomic epidemiology efforts possible. A complete list of data contributors is available in the appendix. Editorial note: The Lancet Group takes a neutral position with respect to territorial claims in published maps and institutional affiliations.

Published
2024
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18. Gram-negative intestinal indigenous microbiota from two Siluriform fishes in a tropical reservoir.

Author

Duarte S, e Silva FC, Zauli DA, Nicoli JR, and Araújo FG

Subjects
Animals, Bacterial Load, Bacteriological Techniques, Brazil, Seasons, Tropical Climate, Biodiversity, Catfishes microbiology, Gram-Negative Bacteria classification, Gram-Negative Bacteria isolation & purification, Intestines microbiology
Abstract

The Gram-negative intestinal microbiota of Hypostomus auroguttatus and Pimelodus maculatus, a detritivorous and an omnivorous fish species, respectively, were compared between fishes from the reservoir and the stretch of the river below the dam of the Funil hydroelectric plant, Rio de Janeiro, Brazil. Four selective culture media were used under aerobic and two under anaerobic conditions. The omnivorous species had microbiota with higher population levels compared to the detritivorous species. The number of morphotypes and population levels of total bacteria, vibrio and Bacteroides tended to be higher in summer and autumn in the reservoir, and not different in the river. The number of morphotypes of enterobacteria and total bacteria were higher in the lotic environment compared with the lentic one. The bacteria Aeromonas hydrophila and Plesiomonas shigelloides and the obligate anaerobic Fusobacterium mortiferum were the most frequently identified microorganisms in the intestine of both H. auroguttatus and P. maculatus. Both season and habitat influenced the Gram-negative intestinal microbiota of H. auroguttatus and P. maculatus. Environmental factors influenced the Gram-negative intestinal microbiota of both species with possible impact on the interrelationship between the fishes and their digestive ecosystem, although the gut microbiota composition of fishes may result from host-specific selective pressures within the gut.

Published
2015
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