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One of the important issues in today's society is drug addiction and drug abuse and the reasons related to it. This has been associated with a lot of factors that affect it; so, it seems that among these factors, family factors play a crucial role in creating tendency towards drugs. Hence the problem of the present study was to determine the influence of family factors (illiterate parents, divorce, parental addiction, family conflicts, lack of parental supervision, parental inattention to proper and reasonable demands of children, and wealth and prosperity of the family) in creating tendency toward industrial and traditional drugs among young people of Lorestan province. The present study was a retrospective study. The sample of the study were 200 young people, 100 of them chosen from addicted and 100 from normal population, which were recruited after being homogenized with the first group based on age, gender, education, and income. In this study, the causes of drug abuse tendency among young people questionnaire (Mohamadi, 1392) was used. MANOVA was also used in order to analyze the data. The results showed that addicted parents or the presence of addicts in families, family conflicts and lack of love in family relationships, lack of proper parental supervision, use of inappropriate parenting practices, and parental divorce and separation had significant effect on tendency toward drugs. The results also showed that the illiteracy of parents, parental negligenc, and household wealth has no significant effects on propensity to addiction. According to the research findings, it can be stated that family factors associated with child behavior have an important role in youth attitudes toward drugs.