Aerosol optical depth (AOD) provides useful information on particulate matter pollution at both regional and global levels. In this study, the long-term datasets of aerosols, meteorological parameters, and enhanced vegetation index (EVI) were used from September 2002 to December 2021 over Turkey. This study examined the spatiotemporal distribution of aerosols and their association with meteorological parameters (temperature (Temp), relative humidity (RH), wind speed (WS)), and EVI over Turkey from 2002 to 2021. Moreover, this study also performed a comparison of AOD retrieved from Aqua with other satellites (Terra, SeaWiFS, and MISR) and ground-based (AERONET) products. The higher mean seasonal AOD (> 0.3) was observed over Southeastern Anatolia Region due to the dust transport from the Saharan Desert and Arabian Peninsula. Moreover, AOD was positively correlated with Temp and WS in the east of Turkey, while negative correlations were observed in the coastal regions. The correlation between AOD and RH was also observed negative in most parts of Turkey. Furthermore, in the coastal region, the correlation between AOD and EVI was found to be positive, whereas a negative correlation was seen over less vegetative areas. The multi-seasonal AOD averages were calculated as 0.187, 0.183, 0.138, and 0.104 for the spring, summer, autumn, and winter seasons, respectively. The most important result of this study is the regional differences in AOD over Turkey. For new studies, AOD should be observed separately for coastal areas and the eastern part of Turkey., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)