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24 results on '"Zhang, Gengshen"'

2. 6D Pose Estimation Based on the Adaptive Weight of RGB-D Feature

Author

Zhang, Gengshen, Ning, Li, Feng, Liangbing, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Zhang, Yong, editor, Xu, Yicheng, editor, and Tian, Hui, editor

Published
2021
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7. Angiotensin II type 1 receptor deficiency protects against the impairment of blood–brain barrier in a mouse model of traumatic brain injury.

Author

Yang, Lijun, Chen, Zeshang, Wan, Xiangdong, Liu, Minghao, Wu, Jianliang, Chen, Yan, Zhang, Gengshen, and Fan, Zhenzeng

Subjects
BRAIN injuries, ANGIOTENSIN II, BLOOD-brain barrier, AMYLOID beta-protein precursor, AQUAPORINS
Abstract

Aquaporin 4 (AQP4), usually expressed at astrocytes end-feet, is a main component of the lymph-lymphatic system and promotes paravascular cerebrospinal fluid-interstitial fluid exchange. Moreover, angiotensin II type 1 (AT1) receptor affects amyloid β (Aβ) levels. This study aimed to detect the effect of AT1 receptor deficiency on the blood-brain barrier (BBB) of traumatic brain injury (TBI) mice and the effect on Aβ level and glial lymphatic circulation. TBI model was built using AT1 receptor knockout mice (AT1-KO) and C57BL/6 mice (wild type, WT). BBB integrity was detected by Evans blue extravasation. The expression of the astrocytic water channel AQP4 and astrocyte activation were evaluated with immunofluorescence. The expressions of amyloid precursor protein (APP), junction protein zonula occludens protein-1 (ZO-1) and occludin in mice brain were detected by Western blot (WB). Aβ levels were assayed by enzyme-linked immunosorbent assay (ELISA). AT1 receptor deficiency defended BBB integrity and rescued occludin and ZO-1 decrease in mice brain induced by TBI. AT1-KO mice had less increase of APP expression and Aβ 1–42, Aβ 1–40 levels compared to WT mice under TBI. Moreover, AT1 receptor deficiency was found to significantly inhibit AQP4 depolarization after TBI. T1 receptor deficiency attenuated TBI-induced impairments of BBB by rescuing tight junction proteins and inhibited AQP4 polarization, thus improving the function of glymphatic system to enhance interstitial Aβ clearance in TBI mice brain. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Evaluation of theTherapeutic Effect of the Hybrid Operation on Patients with Aneurysms Associated with Cerebral Arteriovenous Malformations with different Redekop Classifications

Author

Zhang Chao, Li Peng, Liu Ling, Liu Xiaosong, Zhang Gengshen, Zhao Lei, null Tangkai, Liu Xiaomeng, Wang Xiaoliang, and Wu Jianliang

Subjects
Intracranial Arteriovenous Malformations, Treatment Outcome, Rehabilitation, Humans, Surgery, Intracranial Aneurysm, Neurology (clinical), Cardiology and Cardiovascular Medicine, Embolization, Therapeutic, Intracranial Hemorrhages, Retrospective Studies
Abstract

Intracranial aneurysms associated with cerebral arteriovenous malformations (AVMs) are a rare condition in the clinic, and treatment is very difficult due to their particular anatomical features. We present our experience in the treatment of intracranial aneurysms with AVMs and evaluate the effectiveness and safety of endovascular treatment combined with microsurgical resection (the hybrid operation).This was a single-center retrospective study in our neurosurgical department from January 2015 to January 2021. We collected clinical data from 48 patients with intracranial aneurysms associated with AVMs and categorized them according to Redekop classifications according to the results of cerebral imaging examination to compare the therapeutic effects of endovascular embolization and the hybrid operation.Compared to nonaneurysmal AVMs, intracranial aneurysms with AVMs more often presented with intracranial hemorrhage (P0.05). Massive hematoma and severe neurological impairment were more often found in patients with intracranial aneurysms with AVMs (P0.05). For flow-related aneurysms, the hybrid surgery had a higher one-stage cure rate than endovascular embolization alone (P0.05). Both treatment methods had similar effects on intranidal aneurysms (P0.05). There were no significant differences in prognostic indicators between the two treatments. However, the recurrence rate of AVMs with proximal flow-related aneurysms was lower in patients who underwent the hybrid operation (P0.05).The hybrid operation was safe and effective for patients with intracranial aneurysms associated with AVMs. For flow-related aneurysms, the one-stage cure rate was higher and the recurrence rate was lower with the hybrid operation than with endovascular embolization alone.

Published
2021

16. The Effect of Intracranial Migration of Foley Balloon Catheter after Tumor Resection

Author

Zhang Gengshen, Fan Zhenzeng, Cui Junling, Yang Lijun, Wu Jianliang, Wu Tongmao, and Wang Feng

Subjects
medicine.medical_specialty, Foley, Intracranial tumor, business.industry, Tumor resection, Balloon catheter, Surgery, Resection, medicine.anatomical_structure, Bridging vein, Cortex (anatomy), medicine, medicine.symptom, business, Collapse (medical)
Abstract

The incidence of intracranial tumor is 5% of that of systemic tumor. Some of them are presented as large ones because of slow growth. The higher complications are challenging due to their potential behaviors after resection such as large residual cavity, cortex collapse and bridging vein rupture.

Published
2019

20. The Challenge of the Social Dimensions Under Globalization for Social Security in China

Author

Zhang Gengshen

Subjects
business.industry, Social change, International community, Legislation, International trade, Economic globalization, Labor relations, Social security, Globalization, Market economy, Social system, Economics, business, General Economics, Econometrics and Finance
Abstract

At this very moment, the international community is busy preparing for and fomenting sets of "social rules" that have at their core the formulation of fundamental labor standards to be recognized and implemented internationally. Preparations are also being made to link these rules to the World Trade Organization (WTO), so as to resolve the very serious social problems that economic globalization has brought, and to regulate competition in international trade. Since different countries around the world have different social systems and their economies are at different stages and levels of growth and development, the implementation of these "social rules" will have different types of impact on different nations. As China accelerates its participation in the process of globalization and, in particular, after it joins the WTO, it will very quickly be confronted with enormous pressure from these social rules. Labor legislation, as well as the state of employment and of labor relations in China will suffer a di...

Published
2001

23. A Novel Technology

Author

Yang, Lijun, primary, Wu, Jianliang, additional, Zhang, Gengshen, additional, Zhao, Zongmao, additional, Fan, Zhenzeng, additional, and Wang, Baozhi, additional

Published
2013
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24. A novel technology: percutaneous injection of fibrin glue as a treatment for frontal sinus cerebrospinal fluid rhinorrhea.

Author

Yang L, Wu J, Zhang G, Zhao Z, Fan Z, and Wang B

Subjects
Accidents, Traffic, Adult, Cerebrospinal Fluid Rhinorrhea diagnostic imaging, Craniotomy, Female, Frontal Sinus diagnostic imaging, Frontal Sinus surgery, Humans, Male, Middle Aged, Skull Fractures diagnostic imaging, Skull Fractures surgery, Tomography, X-Ray Computed, Treatment Outcome, Cerebrospinal Fluid Rhinorrhea etiology, Cerebrospinal Fluid Rhinorrhea surgery, Fibrin Tissue Adhesive therapeutic use, Frontal Sinus injuries, Skull Fractures complications
Abstract

In this study, we examined the effectiveness of percutaneous injected fibrin glue as a treatment for frontal sinus cerebrospinal fluid (CSF) rhinorrhea in a series of 4 cases. All 4 patients had fracture in the posterior wall of the frontal sinus. The anterior wall of the frontal sinus was punctured following high-resolution computed tomography imaging. In 3 out of 4 patients with defective skull due to prior frontal craniotomy, direct percutaneous puncture of the frontal sinus was used. Fibrin glue was injected to close the fistula and to seal the rhinorrhea. Surgery procedures lasted for 15-35 minutes (average 27.6 min). Rhinorrhea was stopped in all patients after the surgery, with no recurrence at a 10-month follow-up visit. In 1 case, the glue was expelled by coughing at 2 days after the surgery but was completely stopped with no recurrence after a second attempt. One patient with no recurrence at a 10-month follow-up died of tumor relapse at 12 months. In summary, fibrin glue could be used as a novel treatment for frontal sinus CSF rhinorrhea.

Published
2013
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