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160 results on '"Zhang, Qiuqin"'

15. Effects of Low-Light Stress on Physiological Characteristics of Fruits of Different Muskmelon Varieties.

Author

GENG Xinli, YAO Jun, ZHENG Heyun, XIE Bing, ZHANG Qiuqin, ZHANG Cuihuan, REN Xiaopu, Wang Libin, and QIAN Chunlu

Subjects
MUSKMELON, PHYSIOLOGICAL stress, CAROTENOIDS, CAROTENES, FRUIT, FRUIT development, CARBOHYDRATES, SUCROSE
Abstract

Copyright of Guangdong Agricultural Sciences is the property of South China Agricultural University, Guangdong Academy of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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18. Protective effects and mechanism of Paecilomyces cicadaeTJJ1213 intracellular polysaccharide against H2O2‐induced PC12 cells damage.

Author

Tian, Juanjuan, Xu, Qing, Wang, Xiaomeng, Zhang, Xueliang, Chen, Xiaohong, Rui, Xin, Zhang, Qiuqin, Dong, Mingsheng, and Li, Wei

Subjects
PAECILOMYCES, POLYSACCHARIDES, REACTIVE oxygen species, LACTATE dehydrogenase, OXIDATIVE stress, CICADAS
Abstract

Oxidative stress is a key process in the development of neurodegenerative diseases. More attention is needed to screen natural antioxidants and explore pharmacological mechanisms. Natural product polysaccharides with no toxic side effects have powerful antioxidant activity. Two purified intracellular polysaccharide fractions (IPS1 and IPS2) from Paecilomyces cicadae TJJ1213 was isolated. Then, a model of H2O2‐induced oxidative stress in PC12 cells was established to investigate the neuroprotective role of IPS and elucidate the potential protection mechanism. Results showed that IPS1 and IPS2 reduced reactive oxygen species (ROS) production, inhibited the leakage of lactate dehydrogenase (LDH) and Ca2+ and attenuated the expression of apoptotic proteins. In addition, western blots displayed that IPS1 and IPS2 significantly inhibited mitophagy induced by H2O2 in PC12 cells via PINK/Parkin pathway. Therefore, IPS1 and IPS2 deserved further investigation as protective agents against neurodegenerative diseases. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Exopolysaccharide (LHEPS-1) from Lactobacillus helveticus MB2-1 Induced Apoptosis and G2/M Arrest in Human Liver Cancer HepG-2 Cells.

Author

Xiaomeng Wang, Ji, Juan, Rui, Xin, Chen, Xiaohong, Jiang, Mei, Zhang, Qiuqin, Dong, Mingsheng, and Li, Wei

Subjects
LIVER cancer, CANCER cells, LACTOBACILLUS, REACTIVE oxygen species, APOPTOSIS
Abstract

The aim of this study was to investigate the antitumor activity of exopolysaccharide (EPS) isolated from Lactobacillus helveticus MB2-1. Crude EPS from L. helveticus MB2-1 (LHEPS) was divided into three fractions (LHEPS-1, LHEPS-2, and LHEPS-3). Compared with LHEPS-2 and LHEPS-3, LHEPS-1 exhibited stronger growth inhibition against HepG-2 cells. Thus, the antitumor mechanism of LHEPS-1 with 100 and 600 μg/mL on the HepG-2 cells was evaluated, and we found that LHEPS-1 could enhance the release of lactate dehydrogenase (LDH) in cell culture medium and the amount of reactive oxygen species (ROS). Morphological analysis was performed and indicated that LHEPS-1 could promote HepG-2 cell apoptosis. Additionally, flow cytometric analysis showed that LHEPS-1 exerted a stimulatory effect on apoptosis of HepG-2 cells and induced the cell-cycle arrest at the G2/M phase. Moreover, caspase-3 and caspase-9 could be activated by LHEPS-1, and the results indicated that the induction of caspase-3 and caspase-9 activities may be involved in LHEPS-1-induced apoptosis. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Artificial simulated saliva, gastric and intestinal digestion and fermentation in vitroby human gut microbiota of intrapolysaccharide from Paecilomyces cicadaeTJJ1213

Author

Tian, Juanjuan, Wang, Xiaomeng, Zhang, Xueliang, Chen, Xiaohong, Dong, Mingsheng, Rui, Xin, Zhang, Qiuqin, Jiang, Mei, and Li, Wei

Abstract

In this study, the in vitrodigestion and fermentation of two intra-polysaccharide fractions (IPS1 and IPS2) from Paecilomyces cicadaeTJJ1213 were investigated. The constituent monosaccharides of IPS1 and IPS2 were not changed after simulated saliva, gastric and small intestinal digestion. However, they can be hydrolyzed and utilized by gut microbiota, and short-chain fatty acids (SCFAs) level were increased after IPS1and IPS2 treatments. Furthermore, 16S rRNA sequencing analysis of fermentation samples were performed. Alpha-diversity, beta-diversity and taxonomic composition differences analysis revealed that IPS1 and IPS2 promoted the proliferation of beneficial bacteria and modulated the overall structure of gut microbiota. Taxonomic comparison analysis found that IPS1 increased the relative abundances of beneficial bacteria including Megamonas, Bifidobacteriumand Lactobacillus, while IPS2 could increase the abundance of Bacteroides, Parabacteroidesand Phascolarctobacterium.In addition, they can also decrease the levels of pathogenic bacteria containing Escherichia-Shigella, Klebsiellaand Fusobacterium. These results indicated that IPS from P. cicadaeTJJ1213 could be used as potential candidates for new functional foods.

Published
2023
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33. Isolation, purification, characterization and immunostimulatory activity of an exopolysaccharide produced by Lactobacillus pentosus LZ-R-17 isolated from Tibetan kefir

Author

You, Xiu, primary, Yang, Lin, additional, Zhao, Xiaojuan, additional, Ma, Kai, additional, Chen, Xiaohong, additional, Zhang, Changliang, additional, Wang, Guangxian, additional, Dong, Mingsheng, additional, Rui, Xin, additional, Zhang, Qiuqin, additional, and Li, Wei, additional

Published
2020
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34. Influences of drying methods on the structural, physicochemical and antioxidant properties of exopolysaccharide from Lactobacillus helveticus MB2-1

Author

Xiao, Luyao, primary, Li, Yingying, additional, Tian, Juanjuan, additional, Zhou, Jianzhong, additional, Xu, Qian, additional, Feng, Li, additional, Rui, Xin, additional, Fan, Xia, additional, Zhang, Qiuqin, additional, Chen, Xiaohong, additional, Dong, Mingsheng, additional, and Li, Wei, additional

Published
2020
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