674 results on '"Zhang, Wei‐Jun"'
Search Results
2. 1002 km Twin-Field Quantum Key Distribution with Finite-Key Analysis
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Liu, Yang, Zhang, Wei-Jun, Jiang, Cong, Chen, Jiu-Peng, Ma, Di, Zhang, Chi, Pan, Wen-Xin, Dong, Hao, Xiong, Jia-Min, Zhang, Cheng-Jun, Li, Hao, Wang, Rui-Chun, Lu, Chao-Yang, Wu, Jun, Chen, Teng-Yun, You, Lixing, Wang, Xiang-Bin, Zhang, Qiang, and Pan, Jian-Wei
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Quantum Physics - Abstract
Quantum key distribution (QKD) holds the potential to establish secure keys over long distances. The distance of point-to-point QKD secure key distribution is primarily impeded by the transmission loss inherent to the channel. In the quest to realize a large-scale quantum network, increasing the QKD distance under current technology is of great research interest. Here we adopt the 3-intensity sending-or-not-sending twin-field QKD (TF-QKD) protocol with the actively-odd-parity-pairing method. The experiment demonstrates the feasibility of secure QKD over a 1002 km fibre channel considering the finite size effect. The secure key rate is $3.11\times10^{-12}$ per pulse at this distance. Furthermore, by optimizing parameters for shorter fiber distances, we conducted performance tests on key distribution for fiber lengths ranging from 202 km to 505 km. Notably, the secure key rate for the 202 km, the normal distance between major cities, reached 111.74 kbps., Comment: 18 pages, 3 figures
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- 2023
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3. Characterization of a Superconducting Microstrip Single-Photon Detector Shunted with an External Resistor
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Wang, Yu-Ze, Zhang, Wei-Jun, Xu, Guang-Zhao, Xiong, Jia-Min, Fan, Dong-Hui, Chen, Zhi-Gang, Zhang, Xing-Yu, Wang, Zhen, and You, Li-Xing
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Physics - Instrumentation and Detectors ,Physics - Applied Physics - Abstract
A superconducting microstrip single-photon detector (SMSPD) generally requires a shunt resistor to avoid latching, caused by its high current-carrying capacity and low kinetic inductance. Here, the effect of the shunt resistor on the behaviors of microbridge SMSPDs was investigated. We analyzed the change in equivalent switching current at different shunt resistances in two ways and determined the operating current range using intrinsic dark count rate (iDCR) curves. We observed that the reduction in shunt resistance can increase the operating current range, which helps to improve the internal detection efficiency (IDE) and reduce the iDCR. However, the reduction in the shunt resistance can reduce the pulse amplitude and increase the pulse decay time, which can degrade the timing jitter and count rate performance of the SMSPD. The trends of the experimental results can be qualitatively reproduced using a circuit model for an SMSPD with a shunt resistor, which provides useful information for the selection of shunt resistors. Furthermore, we report the improved detection performance of a helium-ion-irradiated SMSPD shunted with a small resistance of 5.2 {\Omega}. We observed a weak IDE saturation with a bias current at a wavelength up to 2000 nm and a nonlinear relation between detection current and photon energy., Comment: 13 pages, 8 figures, 1 table
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- 2023
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4. Millimeter-scale active area superconducting microstrip single-photon detector fabricated by ultraviolet photolithography
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Xu, Guang-Zhao, Zhang, Wei-Jun, You, Li-Xing, Wang, Yu-Ze, Xiong, Jia-Min, Fan, Dong-Hui, Wu, Ling, Yu, Hui-Qin, Li, Hao, and Wang, Zhen
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Physics - Instrumentation and Detectors ,Physics - Optics - Abstract
The effective and convenient detection of single photons via advanced detectors with a large active area is becoming significant for quantum and classical applications. This work demonstrates the fabrication of a superconducting microstrip single-photon detector (SMSPD) with a millimeter-scale active area via the use of ultraviolet (UV) photolithography. The performances of NbN SMSPDs with different active areas and strip widths are characterized. SMSPDs fabricated by UV photolithography and electron beam lithography with small active areas are also compared from the aspects of the switching current density and line edge roughness. Furthermore, an SMSPD with an active area of 1 mm * 1 mm is obtained via UV photolithography, and during operation at 0.85 K, it exhibits near-saturated internal detection efficiency at wavelengths up to 800 nm. At a wavelength of 1550 nm, the detector exhibits a system detection efficiency of ~5% (7%) and a timing jitter of 102 (144) ps, when illuminated with a light spot of ~18 (600) um in diameter, respectively., Comment: 13 pages, 5 figures, 1 table
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- 2023
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5. Fractal analysis of left ventricular trabeculae in post-STEMI: from acute to chronic phase
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Shi, Ruo-Yang, Wu, Rui, Ran, Jinjun, Tang, Lang-Lang, Wesemann, Luke, Hu, Jiani, Du, Liang, Zhang, Wei-Jun, Xu, Jian-Rong, Zhou, Yan, Zhao, Lei, Pu, Jun, and Wu, Lian-Ming
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- 2024
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6. Experimental Twin-Field Quantum Key Distribution Over 1000 km Fiber Distance
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Liu, Yang, Zhang, Wei-Jun, Jiang, Cong, Chen, Jiu-Peng, Zhang, Chi, Pan, Wen-Xin, Ma, Di, Dong, Hao, Xiong, Jia-Min, Zhang, Cheng-Jun, Li, Hao, Wang, Rui-Chun, Wu, Jun, Chen, Teng-Yun, You, Lixing, Wang, Xiang-Bin, Zhang, Qiang, and Pan, Jian-Wei
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Quantum Physics - Abstract
Quantum key distribution (QKD) aims to generate secure private keys shared by two remote parties. With its security being protected by principles of quantum mechanics, some technology challenges remain towards practical application of QKD. The major one is the distance limit, which is caused by the fact that a quantum signal cannot be amplified while the channel loss is exponential with the distance for photon transmission in optical fiber. Here using the 3-intensity sending-or-not-sending protocol with the actively-odd-parity-pairing method, we demonstrate a fiber-based twin-field QKD over 1002 km. In our experiment, we developed a dual-band phase estimation and ultra-low noise superconducting nanowire single-photon detectors to suppress the system noise to around 0.02 Hz. The secure key rate is $9.53\times10^{-12}$ per pulse through 1002 km fiber in the asymptotic regime, and $8.75\times10^{-12}$ per pulse at 952 km considering the finite size effect. Our work constitutes a critical step towards the future large-scale quantum network., Comment: 47 pages, 17 figures
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- 2023
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7. High-efficiency broadband fiber-to-chip coupler using a 3D nanoprinting microfiber
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Fan, Dong-Hui, Zhang, Xing-Yu, Zhang, Wei-Jun, Ma, Ruo-Yan, Xiong, Jia-Min, Wang, Yu-Ze, Chen, Zhi-Gang, Wang, Zhen, and You, Li-Xing
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Physics - Optics ,Physics - Applied Physics - Abstract
We propose a method for coupling a tapered optical fiber to an inverted tapered SiN waveguide by fabricating a microfiber using 3D nanoprinting lithography. The microfiber consists of three parts: a tapered cladding cap, an S-bend, and a straight part, all composed of high-refractive-index material. Light is adiabatically coupled from the tapered fiber to the printed microfiber through the cladding cap. The light is then transmitted through the S-bend and the straight part with low loss and is finally coupled to the waveguide through the evanescent field. In the simulation, our design can achieve a high coupling efficiency (TE mode) of ~97% at a wavelength of 1542 nm with a wide bandwidth of ~768 nm at the 1-dB cut-off criterion., Comment: 14 pages, 8 figures
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- 2023
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8. Solving Graph Problems Using Gaussian Boson Sampling
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Deng, Yu-Hao, Gong, Si-Qiu, Gu, Yi-Chao, Zhang, Zhi-Jiong, Liu, Hua-Liang, Su, Hao, Tang, Hao-Yang, Xu, Jia-Min, Jia, Meng-Hao, Chen, Ming-Cheng, Zhong, Han-Sen, Wang, Hui, Yan, Jiarong, Hu, Yi, Huang, Jia, Zhang, Wei-Jun, Li, Hao, Jiang, Xiao, You, Lixing, Wang, Zhen, Li, Li, Liu, Nai-Le, Lu, Chao-Yang, and Pan, Jian-Wei
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Quantum Physics - Abstract
Gaussian boson sampling (GBS) is not only a feasible protocol for demonstrating quantum computational advantage, but also mathematically associated with certain graph-related and quantum chemistry problems. In particular, it is proposed that the generated samples from the GBS could be harnessed to enhance the classical stochastic algorithms in searching some graph features. Here, we use Jiuzhang, a noisy intermediate-scale quantum computer, to solve graph problems. The samples are generated from a 144-mode fully-connected photonic processor, with photon-click up to 80 in the quantum computational advantage regime. We investigate the open question of whether the GBS enhancement over the classical stochastic algorithms persists -- and how it scales -- with an increasing system size on noisy quantum devices in the computationally interesting regime. We experimentally observe the presence of GBS enhancement with large photon-click number and a robustness of the enhancement under certain noise. Our work is a step toward testing real-world problems using the existing noisy intermediate-scale quantum computers, and hopes to stimulate the development of more efficient classical and quantum-inspired algorithms.
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- 2023
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9. Reducing current crowding in meander superconducting strip single-photon detectors by thickening bends
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Xiong, Jia-Min, Zhang, Wei-Jun, Xu, Guang-Zhao, You, Li-Xing, Zhang, Xing-Yu, Zhang, Lu, Zhang, Cheng-Jun, Fan, Dong-Hui, Wang, Yu-Ze, Li, Hao, and Wang, Zhen
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Physics - Applied Physics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
To facilitate high optical coupling efficiency and absorptance, the active area of a superconducting nano/microstrip single-photon detector (SNSPD/SMSPD) is often designed as a meander configuration with a high filling factor (e.g., >=0.5). However, the switching current (Isw) of SNSPD/SMSPD, at which the detector switches into the normal state, is significantly suppressed by a geometry-induced "current crowding effect", where there are sharp bends in the strip. Here we propose and experimentally verify an alternative method to reduce current crowding both in SNSPD and SMSPD by directly increasing the thickness of the bends through the deposition and lift-off of a secondary superconducting film. We measure and compare the performance of SNSPDs and SMSPDs with different filling factors and bend configurations, with or without thickened bends. Improvements for detectors were observed in detection efficiency, intrinsic dark count rate, and time jitter, owing to the enhanced Isw. Our method provides a promising way of optimizing SNSPD/SMSPD detection performance., Comment: 9 pages, 9 figures
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- 2021
10. Quantum key distribution over 658 km fiber with distributed vibration sensing
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Chen, Jiu-Peng, Zhang, Chi, Liu, Yang, Jiang, Cong, Zhao, Dong-Feng, Zhang, Wei-Jun, Chen, Fa-Xi, Li, Hao, You, Li-Xing, Wang, Zhen, Chen, Yang, Wang, Xiang-Bin, Zhang, Qiang, and Pan, Jian-Wei
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Quantum Physics - Abstract
Twin-field quantum key distribution (TF-QKD) promises ultra-long secure key distribution which surpasses the rate distance limit and can reduce the number of the trusted nodes in long-haul quantum network. Tremendous efforts have been made towards implementation of TF-QKD, among which, the secure key with finite size analysis can distribute more than 500 km in the lab and in the field. Here, we demonstrate the sending-or-not-sending TF-QKD experimentally, achieving a secure key distribution with finite size analysis over 658 km ultra-low-loss optical fiber, improve the secure distance record by around 100 km. Meanwhile, in a TF-QKD system, any phase fluctuation due to temperature variation and ambient variation during the channel must be recorded and compensated, and all these phase information can then be utilized to sense the channel vibration perturbations. With our QKD system, we recovered the external vibrational perturbations on the fiber generated by an artificial vibroseis and successfully located the perturbation position with a resolution better than 1 km. Our results not only set a new distance record of QKD, but also demonstrate that the redundant information of TF-QKD can be used for remote sensing of the channel vibration, which can find applications in earthquake detection and landslide monitoring besides secure communication., Comment: 20 pages, 4 figures and 1 table
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- 2021
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11. Restriction of vortex motion in superconducting NbN film via ion irradiation
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Xu, Wanting, Chen, Yangyang, Cai, Chuanbing, Zhu, Ping, Fan, Feng, Liu, Zhiyong, Hu, Qingyu, Lu, Wenlai, Zhang, Tongmin, Li, Jun, Zhou, Junjun, Li, Jinyu, Ying, Liliang, Zhang, Wei-Jun, You, Lixing, and Xie, Xiaoming
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- 2023
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12. Phase-Programmable Gaussian Boson Sampling Using Stimulated Squeezed Light
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Zhong, Han-Sen, Deng, Yu-Hao, Qin, Jian, Wang, Hui, Chen, Ming-Cheng, Peng, Li-Chao, Luo, Yi-Han, Wu, Dian, Gong, Si-Qiu, Su, Hao, Hu, Yi, Hu, Peng, Yang, Xiao-Yan, Zhang, Wei-Jun, Li, Hao, Li, Yuxuan, Jiang, Xiao, Gan, Lin, Yang, Guangwen, You, Lixing, Wang, Zhen, Li, Li, Liu, Nai-Le, Renema, Jelmer, Lu, Chao-Yang, and Pan, Jian-Wei
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Quantum Physics ,Physics - Optics - Abstract
The tantalizing promise of quantum computational speedup in solving certain problems has been strongly supported by recent experimental evidence from a high-fidelity 53-qubit superconducting processor1 and Gaussian boson sampling (GBS) with up to 76 detected photons. Analogous to the increasingly sophisticated Bell tests that continued to refute local hidden variable theories, quantum computational advantage tests are expected to provide increasingly compelling experimental evidence against the Extended Church-Turing thesis. In this direction, continued competition between upgraded quantum hardware and improved classical simulations is required. Here, we report a new GBS experiment that produces up to 113 detection events out of a 144-mode photonic circuit. We develop a new high-brightness and scalable quantum light source, exploring the idea of stimulated squeezed photons, which has simultaneously near-unity purity and efficiency. This GBS is programmable by tuning the phase of the input squeezed states. We demonstrate a new method to efficiently validate the samples by inferring from computationally friendly subsystems, which rules out hypotheses including distinguishable photons and thermal states. We show that our noisy GBS experiment passes the nonclassicality test using an inequality, and we reveal non-trivial genuine high-order correlation in the GBS samples, which are evidence of robustness against possible classical simulation schemes. The photonic quantum computer, Jiuzhang 2.0, yields a Hilbert space dimension up to $10^{43}$, and a sampling rate $10^{24}$ faster than using brute-force simulation on supercomputers., Comment: 23 pages, 6 figures. Comments are welcome
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- 2021
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13. Twin-Field Quantum Key Distribution over 511 km Optical Fiber Linking two Distant Metropolitans
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Chen, Jiu-Peng, Zhang, Chi, Liu, Yang, Jiang, Cong, Zhang, Wei-Jun, Han, Zhi-Yong, Ma, Shi-Zhao, Hu, Xiao-Long, Li, Yu-Huai, Liu, Hui, Zhou, Fei, Jiang, Hai-Feng, Chen, Teng-Yun, Li, Hao, You, Li-Xing, Wang, Zhen, Wang, Xiang-Bin, Zhang, Qiang, and Pan, Jian-Wei
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Quantum Physics - Abstract
The basic principle of quantum mechanics guarantee the unconditional security of quantum key distribution (QKD) at the cost of inability of amplification of quantum state. As a result, despite remarkable progress in worldwide metropolitan QKD networks over the past decades, long haul fiber QKD network without trustful relay has not been achieved yet. Here, through sending-or-not-sending (SNS) protocol, we complete a twin field QKD (TF-QKD) and distribute secure keys without any trusted repeater over a 511 km long haul fiber trunk linking two distant metropolitans. Our secure key rate is around 3 orders of magnitudes greater than what is expected if the previous QKD field test system over the same length were applied. The efficient quantum-state transmission and stable single-photon interference over such a long distance deployed fiber paves the way to large-scale fiber quantum networks., Comment: 32 pages, 8 figures
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- 2021
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14. Superconducting microstrip single-photon detector with system detection efficiency over 90% at 1550 nm
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Xu, Guang-Zhao, Zhang, Wei-Jun, You, Li-Xing, Xiong, Jia-Min, Sun, Xing-Qu, Huang, Hao, Ou, Xin, Pan, Yi-Ming, Lv, Chao-Lin, Li, Hao, Wang, Zhen, and Xie, Xiao-Ming
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Physics - Instrumentation and Detectors ,Physics - Optics - Abstract
Generally, a superconducting nanowire single-photon detector (SNSPD) is composed of wires with a typical width of ~100 nm. Recent studies have found that superconducting strips with a micrometer-scale width can also detect single photons. Compared with the SNSPD, the superconducting microstrip single-photon detector (SMSPD) has smaller kinetic inductance, higher working current, and lower requirement in fabrication accuracy, providing potential applications in the development of ultra-large active area detectors. However, the study on SMSPD is still in its infancy, and the realization of its high-performance and practical use remains an opening question. This study demonstrates a NbN SMSPD with a saturated system detection efficiency (SDE) of ~92.2% at a dark count rate of ~200 cps, a polarization sensitivity of ~1.03, and a minimum timing jitter of ~48 ps, at the telecom wavelength of 1550 nm when coupled with a single mode fiber and operated at 0.84 K. Furthermore, the detector's SDE is over 70% when operated at a 2.1-K closed-cycle cryocooler., Comment: 10 pages,7 figures, 2 tables
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- 2021
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15. A 16-channel fiber array-coupled superconducting single-photon detector array with average system detection efficiency over 60% at telecom wavelength
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Zhang, Wei-Jun, Xu, Guang-Zhao, You, Li-Xing, Zhang, Cheng-Jun, Huang, Hao, Ou, Xin, Sun, Xing-Qu, Xiong, Jia-Min, Li, Hao, Wang, Zhen, and Xie, Xiao-Ming
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Physics - Instrumentation and Detectors ,Physics - Optics ,Quantum Physics - Abstract
We report a compact, scalable, and high-performance superconducting nanowire single-photon detector (SNSPD) array by using a multichannel optical fiber array-coupled configuration. For single pixels with an active area of 18 um in diameter and illuminated at the telecom wavelength of 1550 nm, we achieved a pixel yield of 13/16 on one chip, an average system detection efficiency of 69% at a dark count rate of 160 cps, a minimum timing jitter of 74 ps, and a maximum count rate of ~40 Mcps. The optical crosstalk coefficient between adjacent channels is better than -60 dB. The performance of the fiber array-coupled detectors is comparable with a standalone detector coupled to a single fiber. Our method is promising for the development of scalable, high-performance, and high-yield SNSPDs., Comment: 8 pages, 12 figures (including Supplementary Material)
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- 2020
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16. Quantum computational advantage using photons
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Zhong, Han-Sen, Wang, Hui, Deng, Yu-Hao, Chen, Ming-Cheng, Peng, Li-Chao, Luo, Yi-Han, Qin, Jian, Wu, Dian, Ding, Xing, Hu, Yi, Hu, Peng, Yang, Xiao-Yan, Zhang, Wei-Jun, Li, Hao, Li, Yuxuan, Jiang, Xiao, Gan, Lin, Yang, Guangwen, You, Lixing, Wang, Zhen, Li, Li, Liu, Nai-Le, Lu, Chao-Yang, and Pan, Jian-Wei
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Quantum Physics ,Condensed Matter - Other Condensed Matter ,Physics - Optics - Abstract
Gaussian boson sampling exploits squeezed states to provide a highly efficient way to demonstrate quantum computational advantage. We perform experiments with 50 input single-mode squeezed states with high indistinguishability and squeezing parameters, which are fed into a 100-mode ultralow-loss interferometer with full connectivity and random transformation, and sampled using 100 high-efficiency single-photon detectors. The whole optical set-up is phase-locked to maintain a high coherence between the superposition of all photon number states. We observe up to 76 output photon-clicks, which yield an output state space dimension of $10^{30}$ and a sampling rate that is $10^{14}$ faster than using the state-of-the-art simulation strategy and supercomputers. The obtained samples are validated against various hypotheses including using thermal states, distinguishable photons, and uniform distribution., Comment: 23 pages, 5 figures, supplemental information not included but a link is provided. This work is dedicated to the people in the fight against the COVID-19 outbreak during which the final stage of this experiment was carried out
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- 2020
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17. High-speed measurement-device-independent quantum key distribution with integrated silicon photonics
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Wei, Kejin, Li, Wei, Tan, Hao, Li, Yang, Min, Hao, Zhang, Wei-Jun, Li, Hao, You, Lixing, Wang, Zhen, Jiang, Xiao, Chen, Teng-Yun, Liao, Sheng-Kai, Peng, Cheng-Zhi, Xu, Feihu, and Pan, Jian-Wei
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Quantum Physics - Abstract
Measurement-device-independent quantum key distribution (MDI-QKD) removes all detector side channels and enables secure QKD with an untrusted relay. It is suitable for building a star-type quantum access network, where the complicated and expensive measurement devices are placed in the central untrusted relay and each user requires only a low-cost transmitter, such as an integrated photonic chip. Here, we experimentally demonstrate a 1.25 GHz silicon photonic chip-based MDI-QKD system using polarization encoding. The photonic chip transmitters integrate the necessary encoding components for a standard QKD source. We implement random modulations of polarization states and decoy intensities, and demonstrate a finite-key secret rate of 31 bps over 36 dB channel loss (or 180 km standard fiber). This key rate is higher than state-of-the-art MDI-QKD experiments. The results show that silicon photonic chip-based MDI-QKD, benefiting from miniaturization, low-cost manufacture and compatibility with CMOS microelectronics, is a promising solution for future quantum secure networks., Comment: 30 pages, 12 figures
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- 2019
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18. Vacuum Ultraviolet Photoionization Mass Spectrometry and Its Wide Applications in Atmospheric Chemistry
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WEN Zuo-ying, GU Xue-jun, LIN Xiao-xiao, ZHANG Wei-jun, and TANG Xiao-feng
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vacuum ultraviolet (vuv) ,photoionization mass spectrometry (pims) ,atmospheric chemistry ,free radical ,aerosol ,Chemistry ,QD1-999 - Abstract
Atmosphere is a complex mixture system including various gaseous molecules and particulate matters as well as free radicals. The cases of atmospheric pollution often occur in urban or suburban areas during the evolution of industry, and have adverse influences on the human health and daily life. The origins of atmospheric pollution are complicated, which often comprise a series of chemical reactions involving abundant volatile organic compounds (VOCs), free radicals and aerosol particles. How to analyze these species operando is a hot, significant and challenging topic of atmospheric chemistry. In the past decades, benefiting from the rapid development of analytical techniques used in the atmospheric chemistry, abundant reaction mechanisms for the formation of pollutants have been proposed and revealed. However, due to the complexity of atmospheric chemistry, presently the formation mechanisms of atmospheric pollution are still very limited or coarse and deserve to be comprehensively investigated. As a widely used analytical technique, vacuum ultraviolet photoionization mass spectrometry (VUV-PIMS) can provide mass information of molecular ions benefiting from its “soft” ionization at the threshold ionization energy of molecules. Therefore, the obtained VUV photoionization mass spectra have the characters of no or less fragment ions and are easier to be assigned. Then the key chemical components involved in the atmospheric chemical reactions can be identified efficiently, which are very helpful to reveal the complex mechanisms of atmospheric chemical reactions. In this paper, the recent development of VUV-PIMS and its wide applications in atmospheric chemistry were summarized. Several kinds of VUV light sources, including VUV laser, synchrotron radiation, free electron laser and VUV discharge lamp, were presented. In combination with these advanced light sources, several kinds of VUV-PIMS setups were introduced and their advantages were discussed. In addition, the applications of VUVPIMS to analyze atmospheric VOCs, free radicals and their reactions, and the chemical compositions of aerosol particles were reviewed. Concretely, in the aspect to detect VOCs in laboratory or on site, several strategies to improve the sensitivity of detection, in particular the improvement of the photoionization source, were presented here in detail. The analysis of several elusive free radicals and their atmospheric oxidation reactions studied by VUVPIMS were described. Then, the utilization of VUV-PIMS to measure the chemical compositions of aerosols was introduced. Moreover, the perspectives of VUV-PIMS and its further applications in atmospheric chemistry were also discussed.
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- 2023
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19. Artificial intelligence aided precise detection of local recurrence on MRI for nasopharyngeal carcinoma: a multicenter cohort study
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OuYang, Pu-Yun, He, Yun, Guo, Jian-Gui, Liu, Jia-Ni, Wang, Zhi-Long, Li, Anwei, Li, Jiajian, Yang, Shan-Shan, Zhang, Xu, Fan, Wei, Wu, Yi-Shan, Liu, Zhi-Qiao, Zhang, Bao-Yu, Zhao, Ya-Nan, Gao, Ming-Yong, Zhang, Wei-Jun, Xie, Chuan-Miao, and Xie, Fang-Yun
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- 2023
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20. Entanglement of two quantum memories via fibers over dozens of kilometres
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Yu, Yong, Ma, Fei, Luo, Xi-Yu, Jing, Bo, Sun, Peng-Fei, Fang, Ren-Zhou, Yang, Chao-Wei, Liu, Hui, Zheng, Ming-Yang, Xie, Xiu-Ping, Zhang, Wei-Jun, You, Li-Xing, Wang, Zhen, Chen, Teng-Yun, Zhang, Qiang, Bao, Xiao-Hui, and Pan, Jian-Wei
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Quantum Physics - Abstract
Quantum internet will enable a number of revolutionary applications. It relies on entanglement of remote quantum memories over long distances. Despite enormous progresses so far, the maximal physical separation achieved between two nodes is 1.3 km, and challenges for long distance remain. Here we make a significant step forward by entangling two atomic ensembles in one lab via photon transmission through metropolitan-scale fibers. We use cavity enhancement to create bright atom-photon entanglement, and harness quantum frequency conversion to shift the atomic wavelength to telecom. We realize entanglement over 22 km field-deployed fibers via two-photon interference, and entanglement over 50 km coiled fibers via single-photon interference. Our experiment can be extended to physically separated nodes with similar distance as a functional segment for atomic quantum networks, thus paving the way towards establishing atomic entanglement over many nodes and over much longer distance.
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- 2019
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21. Extraction of Vanadium From Vanadium Slag Through a New Technique Route Including Na2O2-Briquetting Roasting Process
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Yue, Hong-Rui, Liu, Jian-Xing, Cheng, Gong-Jin, Xue, Xiang-Xin, and Zhang, Wei-Jun
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- 2022
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22. Free-space coupled, large-active-area superconducting microstrip single-photon detector for photon-counting time-of-flight imaging
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Wang, Yu-Ze, primary, Zhang, Wei-Jun, additional, Zhang, Xing-Yu, additional, Xu, Guang-Zhao, additional, Xiong, Jia-Min, additional, Chen, Zhi-Gang, additional, Hong, Yi-Yu, additional, Liu, Xiao-Yu, additional, Yuan, Pu-Sheng, additional, Wu, Ling, additional, Wang, Zhen, additional, and You, Li-Xing, additional
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- 2024
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23. Toward Scalable Boson Sampling with Photon Loss
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Wang, Hui, Li, Wei, Jiang, Xiao, He, Yu-Ming, Li, Yu-Huai, Ding, Xing, Chen, Ming-Cheng, Qin, Jian, Peng, Cheng-Zhi, Schneider, Christian, Kamp, Martin, Zhang, Wei-Jun, Li, Hao, You, Li-Xing, Wang, Zhen, Dowling, Jonathan P., Hofling, Sven, Lu, Chao-Yang, and Pan, Jian-Wei
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Quantum Physics - Abstract
Boson sampling is a well-defined task that is strongly believed to be intractable for classical computers, but can be efficiently solved by a specific quantum simulator. However, an outstanding problem for large-scale experimental boson sampling is the scalability. Here we report an experiment on boson sampling with photon loss, and demonstrate that boson sampling with a few photons lost can increase the sampling rate. Our experiment uses a quantum-dot-micropillar single-photon source demultiplexed into up to seven input ports of a 16*16 mode ultra-low-loss photonic circuit, and we detect three-, four- and five-fold coincidence counts. We implement and validate lossy boson sampling with one and two photons lost, and obtain sampling rates of 187 kHz, 13.6 kHz, and 0.78 kHz for five-, six- and seven-photon boson sampling with two photons lost, which is 9.4, 13.9, and 18.0 times faster than the standard boson sampling, respectively. Our experiment shows an approach to significantly enhance the sampling rate of multiphoton boson sampling., Comment: 10 pages, 12 figures, submitted
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- 2018
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24. Formation characteristics of CaTiO3 in the vicinity of the calcium ferrite/TiO2 interface
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Yue, Hong-Rui, Cheng, Gong-Jin, Liu, Jian-Xing, Xue, Xiang-Xin, and Zhang, Wei-Jun
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- 2022
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25. Field test of entanglement swapping over 100-km optical fiber with independent 1-GHz-clock sequential time-bin entangled photon-pair sources
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Sun, Qi-Chao, Jiang, Yang-Fan, Mao, Ya-li, You, Li-Xing, Zhang, Wei, Zhang, Wei-Jun, Jiang, Xiao, Chen, Teng-Yun, Li, Hao, Huang, Yi-Dong, Chen, Xian-Feng, Wang, Zhen, Fan, Jingyun, Zhang, Qiang, and Pan, Jian-Wei
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Quantum Physics - Abstract
Realizing long distance entanglement swapping with independent sources in the real-world condition is important for both future quantum network and fundamental study of quantum theory. Currently, demonstration over a few of tens kilometer underground optical fiber has been achieved. However, future applications demand entanglement swapping over longer distance with more complicated environment. We exploit two independent 1-GHz-clock sequential time-bin entangled photon-pair sources, develop several automatic stability controls, and successfully implement a field test of entanglement swapping over more than 100-km optical fiber link including coiled, underground and suspended optical fibers. Our result verifies the feasibility of such technologies for long distance quantum network and for many interesting quantum information experiments.
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- 2017
26. Experimental measurement-device-independent quantum digital signatures over a metropolitan network
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Yin, Hua-Lei, Wang, Wei-Long, Tang, Yan-Lin, Zhao, Qi, Liu, Hui, Sun, Xiang-Xiang, Zhang, Wei-Jun, Li, Hao, Puthoor, Ittoop Vergheese, You, Li-Xing, Andersson, Erika, Wang, Zhen, Liu, Yang, Jiang, Xiao, Ma, Xiongfeng, Zhang, Qiang, Curty, Marcos, Chen, Teng-Yun, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
Quantum digital signatures (QDS) provide a means for signing electronic communications with informationtheoretic security. However, all previous demonstrations of quantum digital signatures assume trusted measurement devices. This renders them vulnerable against detector side-channel attacks, just like quantum key distribution. Here, we exploit a measurement-device-independent (MDI) quantum network, over a 200-square-kilometer metropolitan area, to perform a field test of a three-party measurement-device-independent quantum digital signature (MDI-QDS) scheme that is secure against any detector side-channel attack. In so doing, we are able to successfully sign a binary message with a security level of about 1E-7. Remarkably, our work demonstrates the feasibility of MDI-QDS for practical applications., Comment: 5 pages, 1 figure, 2 tables, supplemental materials included as ancillary file
- Published
- 2017
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27. Diffusion Characteristics of Intermediate in Cr2O3/CaO System and Its Formation Mechanism
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Yue, Hong-Rui, Xue, Xiang-Xin, and Zhang, Wei-Jun
- Published
- 2021
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28. Mechanism of mingjing granules in treating wet age-related macular degeneration based on network pharmacology and experimental verification
- Author
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Li, Xiao-Yu, primary, Liang, Li-Na, additional, Zhang, Wei-Jun, additional, Gao, Yun, additional, and Chen, Qiang, additional
- Published
- 2024
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29. Experimental Quantum Digital Signature over 102 km
- Author
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Yin, Hua-Lei, Fu, Yao, Liu, Hui, Tang, Qi-Jie, Wang, Jian, You, Li-Xing, Zhang, Wei-Jun, Chen, Si-Jing, Wang, Zhen, Zhang, Qiang, Chen, Teng-Yun, Chen, Zeng-Bing, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
Quantum digital signature (QDS) is an approach to guarantee the nonrepudiation, unforgeability and transferability of a signature with the information-theoretical security. All previous experimental realizations of QDS relied on an unrealistic assumption of secure channels and the longest distance is only several kilometers. Here, we have experimentally demonstrated a recently proposed QDS protocol without any secure channel. Exploiting the decoy state modulation, we have successfully signed one bit message through up to 102 km optical fiber. Furthermore, we continuously run the system to sign the longer message "USTC" with 32 bit at the distance of 51 km. Our results pave the way towards the practical application of QDS., Comment: 5+5 page, 3 figures
- Published
- 2016
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30. Measurement device independent quantum key distribution over 404 km optical fibre
- Author
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Yin, Hua-Lei, Chen, Teng-Yun, Yu, Zong-Wen, Liu, Hui, You, Li-Xing, Zhou, Yi-Heng, Chen, Si-Jing, Mao, Yingqiu, Huang, Ming-Qi, Zhang, Wei-Jun, Chen, Hao, Li, Ming Jun, Nolan, Daniel, Zhou, Fei, Jiang, Xiao, Wang, Zhen, Zhang, Qiang, Wang, Xiang-Bin, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
Quantum key distribution (QKD) can provide unconditional secure communication between two distant parties. Although the significance of QKD is undisputed, its feasibility has been questioned because of certain limitations in the practical application of real-life QKD systems. It is a common belief the lack of perfect single-photon source and the existence of detection loss will handicap the feasibility of QKD by creating security loopholes and distance limitations. The measurement device independent QKD (MDIQKD) with decoy-state method removes the security threats from both the imperfect single-photon source and the detection loss. Lengthening the distance and improving the key rate of QKD with such a superior method is thus the central issue in the practical application of QKD. Here, we report the results of MDIQKD over 404 km of ultralow-loss optical fibre and 311 km of standard optical fibre by employing an optimized four-intensity decoy-state method. This record-breaking implementation of MDIQKD method not only provides a new distance record for both MDIQKD and all types of QKD systems, more significantly, it achieves a distance that the traditional BB84 QKD would not be able to achieve with the same detection devices even with ideal single-phone sources. For the first time, our work demonstrates that with the MDIQKD method, imperfect devices can achieve better results than what ideal sources could have achieved. This work represents a significant step towards proving and developing a feasible long-distance QKD., Comment: 15 pages, 3 figures
- Published
- 2016
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31. Observation of quantum fingerprinting beating the classical limit
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Guan, Jian-Yu, Xu, Feihu, Yin, Hua-Lei, Li, Yuan, Zhang, Wei-Jun, Chen, Si-Jing, Yang, Xiao-Yan, Li, Li, You, Li-Xing, Chen, Teng-Yun, Wang, Zhen, Zhang, Qiang, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
Quantum communication has historically been at the forefront of advancements, from fundamental tests of quantum physics to utilizing the quantum-mechanical properties of physical systems for practical applications. In the field of communication complexity, quantum communication allows the advantage of an exponential reduction in the information transmitted over classical communication to accomplish distributed computational tasks. However, to date, demonstrating this advantage in a practical setting continues to be a central challenge. Here, we report an experimental demonstration of a quantum fingerprinting protocol that for the first time surpasses the ultimate classical limit to transmitted information. Ultra-low noise superconducting single-photon detectors and a stable fibre-based Sagnac interferometer are used to implement a quantum fingerprinting system that is capable of transmitting less information than the classical proven lower bound over 20 km standard telecom fibre for input sizes of up to two Gbits. The results pave the way for experimentally exploring the advanced features of quantum communication and open a new window of opportunity for research in communication complexity and testing the foundations of physics., Comment: 19 pages, 4 figures
- Published
- 2016
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32. Comprehensive analysis of liquid-liquid phase separation-related genes in prediction of breast cancer prognosis
- Author
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Huang Yu-Qing, Li Peng-Ping, Sun Ke, Yin Ke-Xing, Zhang Wei-Jun, and Wang Zhen-Yu
- Subjects
liquid-liquid phase separation ,multi-gene risk-score ,prediction model ,breast cancer ,TCGA ,Genetics ,QH426-470 - Abstract
Objective: Liquid-liquid phase separation (LLPS) is a functional unit formed by specific molecules. It lacks a membrane and has been reported to play a crucial role in tumor drug resistance and growth by regulating gene expression and drug distribution. However, whether LLPS could be used to predict cancer prognosis was not clear. This study aimed to construct a prognostic model for breast cancer based on LLPS-correlated genes (LCGs).Methods: LCGs were identified using the PhaSepDB, gene expression profile and clinical characteristics of breast cancer were obtained from TCGA and cBioportal. The PanCancer Atlas (TCGA) cohort was used as the training cohort to construct the prognostic model, while the Nature 2012 and Nat Commun 2016 (TCGA) cohort and GEO data were used as test cohort to perform external verification. Data analysis was performed with R4.2.0 and SPSS20.0.Results: We identified 140 prognosis-related LCGs (pLCGs) (p< 0.01) in all cohorts, 240 pLCGs (p< 0.01) in the luminal cohort, and 28 pLCGs (p< 0.05) in the triple-negative breast cancer (TNBC) cohort. Twelve genes in all cohorts (training cohort: 5/10-year ROC values were 0.76 and 0.77; verification cohort: 5/10-year ROC values were 0.61 and 0.58), eight genes in the luminal cohort (training cohort: 5/10-year ROC values were 0.79 and 0.75; verification cohort: 5/10-year ROC values were 0.62 and 0.62), and four genes in the TNBC cohort (training cohort: 5/10-year ROC values were 0.73 and 0.79; verification cohort: 5/10-year ROC values were 0.55 and 0.54) were screened out to construct the prognostic prediction model. The 17-gene risk-score was constructed in all cohorts (1/3/5-year ROC values were 0.88, 0.83, and 0.81), and the 11-gene risk-score was constructed in the luminal cohort (1/3/5-year ROC values were 0.67, 0.85 and 0.84), and the six-gene risk-score was constructed in the TNBC cohort (1/3/5-year ROC value were 0.87, 0.88 and 0.81). Finally, the risk-score and clinical factors were applied to construct nomograms in all cohorts (1/3/5-year ROC values were 0.89, 0.79 and 0.75, C-index = 0.784), in the luminal cohort (1/3/5-year ROC values were 0.84, 0.83 and 0.85, C-index = 0.803), and in the TNBC cohort (1/3/5-year ROC values were 0.95, 0.84 and 0.77, C-index = 0.847).Discussion: This study explored the roles of LCGs in the prediction of breast cancer prognosis.
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- 2022
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33. Improved teaching-learning-based optimization for estimation of temperature-dependent radiative properties of semitransparent media
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Wei, Lin-Yang, Qi, Hong, Li, Guo-Jun, and Zhang, Wei-Jun
- Published
- 2021
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34. Reaction Mechanism of Calcium Vanadate Formation in V-slag/CaO Diffusion System
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Yue, Hong-Rui, Xue, Xiang-Xin, and Zhang, Wei-Jun
- Published
- 2021
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35. Understanding the Type II Corrosion Mechanism
- Author
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Zhang, Wei-Jun and Sharghi-Moshtaghin, Reza
- Published
- 2021
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36. Measurement-device-independent quantum key distribution over untrustful metropolitan network
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Tang, Yan-Lin, Yin, Hua-Lei, Zhao, Qi, Liu, Hui, Sun, Xiang-Xiang, Huang, Ming-Qi, Zhang, Wei-Jun, Chen, Si-Jing, Zhang, Lu, You, Li-Xing, Wang, Zhen, Liu, Yang, Lu, Chao-Yang, Jiang, Xiao, Ma, Xiongfeng, Zhang, Qiang, Chen, Teng-Yun, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
Quantum cryptography holds the promise to establish an information-theoretically secure global network. All field tests of metropolitan-scale quantum networks to date are based on trusted relays. The security critically relies on the accountability of the trusted relays, which will break down if the relay is dishonest or compromised. Here, we construct a measurement-device-independent quantum key distribution (MDIQKD) network in a star topology over a 200 square kilometers metropolitan area, which is secure against untrustful relays and against all detection attacks. In the field test, our system continuously runs through one week with a secure key rate ten times larger than previous result. Our results demonstrate that the MDIQKD network, combining the best of both worlds --- security and practicality, constitutes an appealing solution to secure metropolitan communications., Comment: 17 pages, 4 figures
- Published
- 2015
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37. Design and experimental tests of an active cooling system for a kind of in-vessel inspection manipulator
- Author
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Du, Liang, Zhang, Wei-Jun, and Yuan, Jian-Jun
- Published
- 2020
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38. Detection of Chemical Compositions of Ultrafine Nanoparticles by a Vacuum Ultraviolet Photoionization Nucleation Aerosol Mass Spectrometer
- Author
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WEN, Zuo-Ying, TANG, Xiao-Feng, WANG, Tao, GU, Xue-Jun, and ZHANG, Wei-Jun
- Published
- 2020
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39. A Vacuum Ultraviolet Photoionization Time-of-Flight Mass Spectrometer for Investigation of Free Radical Reaction
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WANG, Tao, TANG, Xiao-Feng, WEN, Zuo-Ying, ZHANG, Cui-Hong, and ZHANG, Wei-Jun
- Published
- 2020
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40. 1002 km twin-field quantum key distribution with finite-key analysis
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Liu, Yang, primary, Zhang, Wei-Jun, additional, Jiang, Cong, additional, Chen, Jiu-Peng, additional, Ma, Di, additional, Zhang, Chi, additional, Pan, Wen-Xin, additional, Dong, Hao, additional, Xiong, Jia-Min, additional, Zhang, Cheng-Jun, additional, Li, Hao, additional, Wang, Rui-Chun, additional, Lu, Chao-Yang, additional, Wu, Jun, additional, Chen, Teng-Yun, additional, You, Lixing, additional, Wang, Xiang-Bin, additional, Zhang, Qiang, additional, and Pan, Jian-Wei, additional
- Published
- 2023
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- View/download PDF
41. Field Test of Measurement-Device-Independent Quantum Key Distribution
- Author
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Tang, Yan-Lin, Yin, Hua-Lei, Chen, Si-Jing, Liu, Yang, Zhang, Wei-Jun, Jiang, Xiao, Zhang, Lu, Wang, Jian, You, Li-Xing, Guan, Jian-Yu, Yang, Dong-Xu, Wang, Zhen, Liang, Hao, Zhang, Zhen, Zhou, Nan, Ma, Xiongfeng, Chen, Teng-Yun, Zhang, Qiang, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
A main type of obstacles of practical applications of quantum key distribution (QKD) network is various attacks on detection. Measurement-device-independent QKD (MDIQKD) protocol is immune to all these attacks and thus a strong candidate for network security. Recently, several proof-of-principle demonstrations of MDIQKD have been performed. Although novel, those experiments are implemented in the laboratory with secure key rates less than 0.1 bps. Besides, they need manual calibration frequently to maintain the system performance. These aspects render these demonstrations far from practicability. Thus, justification is extremely crucial for practical deployment into the field environment. Here, by developing an automatic feedback MDIQKD system operated at a high clock rate, we perform a field test via deployed fiber network of 30 km total length, achieving a 16.9 bps secure key rate. The result lays the foundation for a global quantum network which can shield from all the detection-side attacks., Comment: 6 pages, 3 figures
- Published
- 2014
42. Measurement-device-independent quantum key distribution over 200 km
- Author
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Tang, Yan-Lin, Yin, Hua-Lei, Chen, Si-Jing, Liu, Yang, Zhang, Wei-Jun, Jiang, Xiao, Zhang, Lu, Wang, Jian, You, Li-Xing, Guan, Jian-Yu, Yang, Dong-Xu, Wang, Zhen, Liang, Hao, Zhang, Zhen, Zhou, Nan, Ma, Xiongfeng, Chen, Teng-Yun, Zhang, Qiang, and Pan, Jian-Wei
- Subjects
Quantum Physics - Abstract
Measurement-device-independent quantum key distribution (MDIQKD) protocol is immune to all attacks on detection and guarantees the information-theoretical security even with imperfect single photon detectors. Recently, several proof-of-principle demonstrations of MDIQKD have been achieved. Those experiments, although novel, are implemented through limited distance with a key rate less than 0.1 bps. Here, by developing a 75 MHz clock rate fully-automatic and highly-stable system, and superconducting nanowire single photon detectors with detection efficiencies more than 40%, we extend the secure transmission distance of MDIQKD to 200 km and achieve a secure key rate of three orders of magnitude higher. These results pave the way towards a quantum network with measurement-device-independent security., Comment: 5 pages, 2 figures
- Published
- 2014
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43. Synthesis and energy storage properties of N/O co-doped porous carbon nanoribbons
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KAN Kan, WANG Jue, FU Dong, SONG Mei-hui, ZHANG Wei-jun, and ZHANG Xiao-chen
- Subjects
heteroatom doped ,porous carbon ,carbon nanoribbon ,energy storage property ,super-capacitor ,Materials of engineering and construction. Mechanics of materials ,TA401-492 - Abstract
The N/O co-doped porous carbon nanoribbons (PCNR) have been prepared via a template polymerization synchronous chemical activation route. The PCNR samples were characterized by SEM, TEM, FTIR, Raman, XRD, BET and XPS. The results show that the PCNR presents a 3D connected ribbon structure. The surface of carbon nanoribbons is porous. The PCNR800 activated at 800 ℃ presents a large specific surface area of 2342 m2/g, high-level nitrogen atom doping of 10.75% and oxygen atom doping of 13.90%. As supercapacitor electrode materials, the typical PCNR800 sample exhibits excellent energy storage characteristics. The PCNR800 supercapacitor shows a high specific capacitance of 58.8 F/g (1.0 A/g). A high energy density of 73.3 Wh/kg at a power density of 1.5 kW/kg can be achieved. The specific capacitance of the supercapacitor was 96.5% of the initial specific capacitance and the columbic efficiency still remains above 99% after 5000 cycles.
- Published
- 2020
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44. Entanglement of two quantum memories via fibres over dozens of kilometres
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Yu, Yong, Ma, Fei, Luo, Xi-Yu, Jing, Bo, Sun, Peng-Fei, Fang, Ren-Zhou, Yang, Chao-Wei, Liu, Hui, Zheng, Ming-Yang, Xie, Xiu-Ping, Zhang, Wei-Jun, You, Li-Xing, Wang, Zhen, Chen, Teng-Yun, Zhang, Qiang, Bao, Xiao-Hui, and Pan, Jian-Wei
- Subjects
Quantum theory -- Research ,Fiber optics -- Usage ,Quantum computing -- Research ,Fiber optics ,Environmental issues ,Science and technology ,Zoology and wildlife conservation - Abstract
A quantum internet that connects remote quantum processors.sup.1,2 should enable a number of revolutionary applications such as distributed quantum computing. Its realization will rely on entanglement of remote quantum memories over long distances. Despite enormous progress.sup.3-12, at present the maximal physical separation achieved between two nodes is 1.3 kilometres.sup.10, and challenges for longer distances remain. Here we demonstrate entanglement of two atomic ensembles in one laboratory via photon transmission through city-scale optical fibres. The atomic ensembles function as quantum memories that store quantum states. We use cavity enhancement to efficiently create atom-photon entanglement.sup.13-15 and we use quantum frequency conversion.sup.16 to shift the atomic wavelength to telecommunications wavelengths. We realize entanglement over 22 kilometres of field-deployed fibres via two-photon interference.sup.17,18 and entanglement over 50 kilometres of coiled fibres via single-photon interference.sup.19. Our experiment could be extended to nodes physically separated by similar distances, which would thus form a functional segment of the atomic quantum network, paving the way towards establishing atomic entanglement over many nodes and over much longer distances. The entanglement of two atomic-ensemble quantum memories via optical fibres, enabled by the use of cavity enhancement and quantum frequency conversion, is demonstrated over dozens of kilometres., Author(s): Yong Yu [sup.1] [sup.2] [sup.3] , Fei Ma [sup.1] [sup.2] [sup.3] [sup.4] , Xi-Yu Luo [sup.1] [sup.2] [sup.3] , Bo Jing [sup.1] [sup.2] [sup.3] , Peng-Fei Sun [sup.1] [sup.2] [...]
- Published
- 2020
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45. CD39 expression defines exhausted CD4+ T cells associated with poor survival and immune evasion in human gastric cancer.
- Author
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Duan, Zhen‐quan, Li, Yu‐xian, Qiu, Yuan, Shen, Yang, Wang, Ying, Zhang, Yuan‐yuan, Zhu, Bao‐hang, Yu, Xiao‐hong, Tan, Xue‐ling, Chen, Weisan, Zhuang, Yuan, Cheng, Ping, Zhang, Wei‐jun, Zou, Quan‐ming, Ma, Dai‐yuan, and Peng, Liu‐sheng
- Subjects
T cells ,T helper cells ,REGULATORY T cells ,STOMACH cancer ,T-cell exhaustion - Abstract
Objectives: CD4+ T cell helper and regulatory function in human cancers has been well characterised. However, the definition of tumor‐infiltrating CD4+ T cell exhaustion and how it contributes to the immune response and disease progression in human gastric cancer (GC) remain largely unknown. Methods: A total of 128 GC patients were enrolled in the study. The expression of CD39 and PD‐1 on CD4+ T cells in the different samples was analysed by flow cytometry. GC‐infiltrating CD4+ T cell subpopulations based on CD39 expression were phenotypically and functionally assessed. The role of CD39 in the immune response of GC‐infiltrating T cells was investigated by inhibiting CD39 enzymatic activity. Results: In comparison with CD4+ T cells from the non‐tumor tissues, significantly more GC‐infiltrating CD4+ T cells expressed CD39. Most GC‐infiltrating CD39+CD4+ T cells exhibited CD45RA−CCR7− effector–memory phenotype expressing more exhaustion‐associated inhibitory molecules and transcription factors and produced less TNF‐α, IFN‐γ and cytolytic molecules than their CD39−CD4+ counterparts. Moreover, ex vivo inhibition of CD39 enzymatic activity enhanced their functional potential reflected by TNF‐α and IFN‐γ production. Finally, increased percentages of GC‐infiltrating CD39+CD4+ T cells were positively associated with disease progression and patients' poorer overall survival. Conclusion: Our study demonstrates that CD39 expression defines GC‐infiltrating CD4+ T cell exhaustion and their immunosuppressive function. Targeting CD39 may be a promising therapeutic strategy for treating GC patients. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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46. PGC-1α regulates critical period onset/closure, mediating cortical plasticity
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Zhang, Wei-Jun, primary, Shi, Hou-Zhen, additional, Guo, Mei-Na, additional, Xu, Long-Fei, additional, Zhai, Hong-Ru, additional, Liu, Zi-Zhong, additional, Zhu, Yong-Qiang, additional, Zhang, Wei-Ning, additional, and Wang, Jia, additional
- Published
- 2023
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- View/download PDF
47. Influence analysis of the furnace wall emissivity on heating process
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Yi, Zhi, Zhang, Wei-jun, Yang, Qiang-da, Li, Guo-jun, and Chen, Hai-geng
- Published
- 2018
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- View/download PDF
48. Design and qualification tests of a robotic joint module for tokamak in-vessel manipulator use
- Author
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Du, Liang, Feng, Jia-Bo, Wang, Hua, and Zhang, Wei-jun
- Published
- 2018
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- View/download PDF
49. Experimental Twin-Field Quantum Key Distribution over 1000 km Fiber Distance
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Liu, Yang, primary, Zhang, Wei-Jun, additional, Jiang, Cong, additional, Chen, Jiu-Peng, additional, Zhang, Chi, additional, Pan, Wen-Xin, additional, Ma, Di, additional, Dong, Hao, additional, Xiong, Jia-Min, additional, Zhang, Cheng-Jun, additional, Li, Hao, additional, Wang, Rui-Chun, additional, Wu, Jun, additional, Chen, Teng-Yun, additional, You, Lixing, additional, Wang, Xiang-Bin, additional, Zhang, Qiang, additional, and Pan, Jian-Wei, additional
- Published
- 2023
- Full Text
- View/download PDF
50. Solving Graph Problems Using Gaussian Boson Sampling
- Author
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Deng, Yu-Hao, primary, Gong, Si-Qiu, additional, Gu, Yi-Chao, additional, Zhang, Zhi-Jiong, additional, Liu, Hua-Liang, additional, Su, Hao, additional, Tang, Hao-Yang, additional, Xu, Jia-Min, additional, Jia, Meng-Hao, additional, Chen, Ming-Cheng, additional, Zhong, Han-Sen, additional, Wang, Hui, additional, Yan, Jiarong, additional, Hu, Yi, additional, Huang, Jia, additional, Zhang, Wei-Jun, additional, Li, Hao, additional, Jiang, Xiao, additional, You, Lixing, additional, Wang, Zhen, additional, Li, Li, additional, Liu, Nai-Le, additional, Lu, Chao-Yang, additional, and Pan, Jian-Wei, additional
- Published
- 2023
- Full Text
- View/download PDF
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