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14 results on '"Zhang, Xi-qi"'

7. Water and mass transport in low-dimensional confined structures

Author

Wen Li-Ping, Zhang Xi-Qi, and Jiang Lei

Subjects
Water flow, Graphene, General Physics and Astronomy, Surface forces apparatus, Carbon nanotube, Fluid transport, 01 natural sciences, law.invention, Surface tension, Contact angle, Chemical physics, law, 0103 physical sciences, Wetting, 010306 general physics
Abstract

Water and mass transport in low-dimensional confined structures is of great importance in solving many challenging problems in interface chemistry and fluid mechanics,and presents versatile applications including mass transport,catalysis,chemical reaction,and nanofabrication.Recent achievements of water and mass transport in low-dimensional confined structures are summarized.Water flow confined in nanochannels with different wettability reveals the viscosity in the interface region increases as the contact angle decreases,whereas the flow capacity of confined water increases as the contact angle increases.Small difference in the nanochannel size has a big effect on the confined water flow,especially for nanochannels with a diameter smaller than 10 nm.The phenomena of ultrafast mass transport are universal in the nanochannels with smaller diameter (

Published
2019

14. [Slow-release recombinant human bone morphogenetic protein-2 suppresses chromium wear particle-induced osteolysis in rats].

Author

Li G, Li Q, Lin LJ, Duan X, and Zhang XQ

Subjects
Animals, Bone Resorption prevention & control, Chromium chemistry, Delayed-Action Preparations, Disease Models, Animal, Female, Male, Osteolysis etiology, Particle Size, Rats, Rats, Sprague-Dawley, Recombinant Proteins pharmacology, Skull, Arthroplasty, Replacement adverse effects, Bone Morphogenetic Protein 2 pharmacology, Bone Transplantation, Chromium adverse effects, Osteolysis prevention & control, Transforming Growth Factor beta pharmacology
Abstract

Objective: To observe the effect of a slow-release recombinant human bone morphogenetic protein-2 (rhBMP-2) formulation on the expressions of receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) in a murine air pouch model of bone implantation., Methods: A cranial bone allograft was implanted in the air pouch induced on the back of the recipients. The rat models were then randomized into 5 groups, including a blank control group, chromium particle group, and 3 rhBMP-2 groups receiving 50, 100 or 200 µg/L slow-release rhBMP-2 in addition to chromium particles. Three weeks later, the expressions of RANKL and OPG in the air pouch was detected using Western blotting and RT-PCR, and the positively stained area for osteoclasts in the bone graft was determined with TRAP staining for drug effect assessment., Results: RANKL and OPG expressions were found in the air pouches in all the 5 groups. RANKL and OPG protein and mRNA expressions, RANKL/OPG ratio and osteoclast staining area in the bone graft were the highest in chromium particle group (P<0.05), but were significantly decreased by treatment with the slow-release rhBMP-2 formulation (P<0.05); the measurements showed no significant differences between the blank control group and 200 µg/L rhBMP-2 group (P>0.05)., Conclusion: Chromium particles can cause osteolysis by increasing the RANKL/OPG ratio in rats, and intervention with slow-release rhBMP-2 can significantly promote bone formation and suppress bone resorption by decreasing RANKL/OPG ratio.

Published
2012

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